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Image showing the global movement of lipids in a model planar membrane
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Posters win prizes at ion channels meetings

Maria Musgaard and Sonya Hanson from the Department’s Structural Bioinformatics and Computational Biochemistry Unit won poster prizes at the recent meeting in Oxford of OXION, the Ion Channels and Disease Initiative.

Capsaicin localisation (yellow sticks) in a lipid bilayer, predicted via equilibrium MD simulation, with a homology model of the  TRPV1 ion channel. The magenta spheres show the intracellular tyrosine crucial to the capsaicin-TRPV1 interaction

Capsaicin localisation (yellow sticks) in a lipid bilayer, predicted via equilibrium MD simulation, with a homology model of the TRPV1 ion channel. The magenta spheres show the intracellular tyrosine crucial to the capsaicin-TRPV1 interaction

Maria is a postdoc in the lab of Dr Phil Biggin. Sonya is a DPhil student on the NIH-Oxford-Cambridge Scholars program working in the labs of Professor Mark Sansom and Dr Simon Newstead in the Department, and Dr Kenton J. Swartz at the National Institute of Neurological Disorders and Stroke at the NIH in Bethesda, MD.

This was the 11th annual Ion Channels meeting of the OXION initiative that encompasses all aspects of ion channels, from the gene through to the clinic. It brings together research groups in Oxford, Cambridge, London and MRC Harwell. Phil Biggin and Mark Sansom are members of the consortium.

As well as talks and poster presentations by OXION groups, the programme included some international speakers. Maria’s poster, ‘Explaining the regulatory effect of monovalent ions on kainate receptors’ and Sonya’s, ‘Insights on the intramembrane capsaicin binding site of TRPV1 from molecular dynamics simulations in explicit lipid bilayers’, won two of the three poster prizes.

Maria's poster also won a prize at another meeting the week earlier. ‘Ion Channels in Health and Disease: a symposium to celebrate the 50th anniversary of the Nobel Prize awarded to Alan Hodgkin and Andrew Huxley’, was held in Cambridge on 16-17 September. It attracted national and international participants and many international speakers.

 

 

 

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