Department of Biochemistry University of Oxford Department of Biochemistry
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Anaphase bridges in fission yeast cells
Whitby lab
Lactose permease represented using bending cylinders in Bendix software
Caroline Dahl, Sansom lab
Epithelial cells in C. elegans showing a seam cell that failed to undergo cytokinesis
Serena Ding, Woollard lab
Collage of Drosophila third instar larva optic lobe
Lu Yang, Davis lab
First year Biochemistry students at a practical class
Image showing the global movement of lipids in a model planar membrane
Matthieu Chavent, Sansom lab
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Elena Seiradake awarded a Wellcome Trust Senior Research Fellowship

Dr Elena Seiradake

Dr Elena Seiradake

Dr Elena Seiradake has been awarded the prestigious Senior Research Fellowship by the Wellcome Trust, for her research into the role of adhesion G-protein coupled receptors (GPCRs) in brain development. Elena joined Biochemistry in 2014 as an independent group leader to study the structure and function of cell surface receptors in neural and vascular development. A major breakthrough in her laboratory revealed that the adhesion GPCR 'Latrophilin' forms large structured assemblies in the presence of two other cell surface receptors 'FLRT' and 'Unc5'. Depending on the cellular context, distinct super-complexes with unique functional properties are formed. Elena’s long-term aim is to understand the functions of distinct receptor-ligand complexes through a detailed knowledge of their structures and signalling properties during neural and vascular development of the brain.

Elena’s work will benefit from the state-of-the-art facilities at Biochemistry, such as the automated crystallisation facility, the Micron imaging facility and the recently acquired cryo-EM microscopes.

Further details of Elena’s recent work can be found at:

dx.doi.org/10.1038/ncomms11184

www.sciencedirect.com/science/article/pii/S0969212615000374

 

 

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