Department of Biochemistry University of Oxford Department of Biochemistry
University of Oxford
South Parks Road
Oxford OX1 3QU

Tel: +44 (0)1865 613200
Fax: +44 (0)1865 613201
Image showing the global movement of lipids in a model planar membrane
Matthieu Chavent, Sansom lab
Anaphase bridges in fission yeast cells
Whitby lab
Lactose permease represented using bending cylinders in Bendix software
Caroline Dahl, Sansom lab
Epithelial cells in C. elegans showing a seam cell that failed to undergo cytokinesis
Serena Ding, Woollard lab
Collage of Drosophila third instar larva optic lobe
Lu Yang, Davis lab
First year Biochemistry students at a practical class
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Wellcome Trust Studentships in Chromosome and Developmental Biology

Wellcome Trust D.Phil Programme in Chromosome & Developmental Biology
The Cell in Heredity and Development (MSDTC)
Wellcome Trust Studentships: 5 per annum

Programme Website

A four-year D.Phil. Programme in Chromosome & Developmental Biology, supported by the Wellcome Trust, will provide training in in a wide range of biochemical, genetic and cell biological approaches specifically tailored for research into chromosome and developmental biology. Students will have the opportunity to study how changes in the state of chromosomal proteins or RNAs specify changes in cell behaviour, how these changes arise and are propagated, how gametes are produced from germ cells, how the genome is propagated and maintained in the germline and in somatic cells, how chromosomes are recombined during meiosis, what factors determine whether chromosomes inherit the privilege of entering the germ line, patterns of cell division during embryogenesis, and finally whether different principles govern the duplication and segregation of prokaryotic and eukaryotic genomes. Students spend the first year learning a range of biochemical, genetic and cell biological techniques by undertaking short projects in different laboratories and by following taught courses. These elements are intended to expose students to possible thesis advisers and prepare them for their doctoral work. Students can then make an informed choice of their main thesis research project and submit a research proposal for years 2-4. Students are expected to submit their thesis by the end of year.

The Wellcome Trust provides generous funds covering research costs, Fees at the UK/EU Student rate and a living allowance no less than £19,919 p.a. provided good progress is made each year. Non-EU candidates must also apply for Clarendon and any other scholarships to fund the difference between Non-EU and EU fees for four years.

To Apply:

Please apply for course 003940 as instructed at, and provide supporting materials, to arrive no later than the closing date. A Statement of Study plans is required to be submitted by the closing date, no more than 1000 words and should describe up to 3 possible ongoing research areas which you would like to pursue with strong interest and enthusiasm. Your personal statement may briefly also refer to your research experience at least briefly; your research experiences should be elaborated further in your CV. No research proposal is required.

List of participating faculty in the Department of Biochemistry:

Dr Bungo Akiyoshi
Evolutionary cell biology of chromosome segregation
Prof Francis Barr
Spatial and temporal control of mitosis and cytokinesis
Prof Neil Brockdorff
Epigenetic mechanisms in X chromosome inactivation
Dr Martin Cohn
Maintenance of genome stability and DNA repair in human
Prof Ilan Davis
Elucidating the molecular mechanism of mRNA localization
Dr Rob Klose
Epigenetic regulation of chromatin function
Dr Nick Lakin
Detection, signalling and repair of DNA damage
Prof Louis Mehadevan
Chromatin modifications at inducible genes in mammalian cells
Prof Jane Mellor
14-3-3 proteins in growth and development
Prof Kim Nasmyth
Cohesin function during cell division and development
Dr Catherine Pears
Histone modification in development
Dr Lidia Vasilieva
Post-transcriptional regulation of gene expression in eukaryotes
Prof Matthew Whitby
Genetic recombination and DNA repair in eukaryotes
Dr Alison Woollard
Controlling stem cell proliferation in C. elegans

Please Contact

The Medical Sciences Doctoral Training Centre (MSDTC) Administrator
University of Oxford
Medical Sciences Graduate Studies Office
Level 3, John Radcliffe Hospital
Oxford OX3 9DU

Application Deadline: 9/1/2015 (12 noon midday UK GMT)











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