Department of Biochemistry University of Oxford Department of Biochemistry
University of Oxford
South Parks Road
Oxford OX1 3QU

Tel: +44 (0)1865 613200
Fax: +44 (0)1865 613201
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Wellcome Trust Studentships in Chromosome and Developmental Biology

Wellcome Trust D.Phil Programme in Chromosome & Developmental Biology
The Cell in Heredity and Development (MSDTC)
Wellcome Trust Studentships: 5 per annum

Programme Website

A four-year D.Phil. Programme in Chromosome & Developmental Biology, supported by the Wellcome Trust, will provide training in in a wide range of biochemical, genetic and cell biological approaches specifically tailored for research into chromosome and developmental biology. Students will have the opportunity to study how changes in the state of chromosomal proteins or RNAs specify changes in cell behaviour, how these changes arise and are propagated, how gametes are produced from germ cells, how the genome is propagated and maintained in the germline and in somatic cells, how chromosomes are recombined during meiosis, what factors determine whether chromosomes inherit the privilege of entering the germ line, patterns of cell division during embryogenesis, and finally whether different principles govern the duplication and segregation of prokaryotic and eukaryotic genomes. Students spend the first year learning a range of biochemical, genetic and cell biological techniques by undertaking short projects in different laboratories and by following taught courses. These elements are intended to expose students to possible thesis advisers and prepare them for their doctoral work. Students can then make an informed choice of their main thesis research project and submit a research proposal for years 2-4. Students are expected to submit their thesis by the end of year.

The Wellcome Trust provides generous funds covering research costs, Fees at the UK/EU Student rate and a living allowance no less than £19,919 p.a. provided good progress is made each year. Non-EU candidates must also apply for Clarendon and any other scholarships to fund the difference between Non-EU and EU fees for four years.

To Apply:

Please apply for course 003940 as instructed at, and provide supporting materials, to arrive no later than the closing date. A Statement of Study plans is required to be submitted by the closing date, no more than 1000 words and should describe up to 3 possible ongoing research areas which you would like to pursue with strong interest and enthusiasm. Your personal statement may briefly also refer to your research experience at least briefly; your research experiences should be elaborated further in your CV. No research proposal is required.

List of participating faculty in the Department of Biochemistry:


Prof Francis Barr

Spatial and temporal control of mitosis and cytokinesis

Prof Neil Brockdorff

Epigenetic mechanisms in X chromosome inactivation

Dr Martin Cohn

Maintenance of genome stability and DNA repair in human

Prof Ilan Davis

Elucidating the molecular mechanism of mRNA localization

Dr Rob Klose

Epigenetic regulation of chromatin function

Dr Nick Lakin

Detection, signalling and repair of DNA damage

Prof Louis Mehadevan

Chromatin modifications at inducible genes in mammalian cells

Dr Jane Mellor

14-3-3 proteins in growth and development

Prof Kim Nasmyth

Cohesin function during cell division and development

Dr Catherine Pears

Histone modification in development

Prof David Sherratt

Bacterial chromosome dynamics

Dr Lidia Vasilieva

Post-transcriptional regulation of gene expression in eukaryotes

Prof Matthew Whitby

Genetic recombination and DNA repair in eukaryotes

Dr Alison Woollard

Controlling stem cell proliferation in C. elegans


Please Contact

The Medical Sciences Doctoral Training Centre (MSDTC) Administrator
University of Oxford
Medical Sciences Graduate Studies Office
Level 3, John Radcliffe Hospital
Oxford OX3 9DU

Application Deadline: 10/1/2014






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