Department of Biochemistry University of Oxford Department of Biochemistry
University of Oxford
South Parks Road
Oxford OX1 3QU

Tel: +44 (0)1865 613200
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E. F. Garman and M. Weik
Radiation Damage in Macromolecular Crystallography
Protein Crystallography: Methods in Molecular Biology (2017) Volume 1607 (Ch. 20 pp. 467-489)
E. F. Garman and M. Weik
X-ray radiation damage to biological macromolecules: further insights
J. Synchrotron Rad. (2017) 24, 1-6.
C. S. Bury, I. Carmichael and E. F. Garman
OH cleavage from tyrosine: debunking a myth
J. Synchrotron Rad. (2017) 24, 7-18.
J. C. Brooks-Bartlett, R. A. Batters, C. S. Bury, E. D. Lowe, H. M. Ginn, A. Round and E. F. Garman
Development of tools to automate qu­antitative analysis of radiation damage in SAXS experiments
J. Synchrotron Rad. (2017) 24, 63-72.


A. C. W. Pike, E. F. Garman, T. Krojer, F. von Delft and E. P. Carpenter
An Overview of Heavy Atom Derivatization of Protein Crystals
Acta Cryst. D (2016) 72, 303-318.
S. Tsukui, F. Kimura, E. F. Garman, S. Baba, N. Mizuno, B. Mikami and T. Kimura
X-ray Crystal Structure Analysis of Magnetically Oriented Microcrystals of Lysozyme at 1.8 Å Resolution
J. Appl. Cryst. (2016) 49, 457-461.
C. S. Bury, J. E. McGeehan, A. A. Antson, I. Carmichael, M. Gerstel, M. B. Shevtsov and E. F. Garman
RNA protects a nucleoprotein complex against radiation damage
Acta Cryst. D (2016) 72, 648-657
E. F. Garman
Entry for Professor Dame Louise N. Johnson for the National Dictionary of Biography
OUP Jan (2016) 
C. S. Bury, I. Carmichael, J. E. McGeehan and E. F. Garman
Radiation damage within nucleoprotein complexes studied by macromolecular X-ray crystallography
Radiat. Phys. Chem. (2016) 128, 118-125


J. C. Brooks-Bartlett and E. F. Garman
The Nobel Science: 100 years of Crystallography
Interdisciplinary Science Reviews (2015) 72, 244-264.
M. Gerstel, C. M. Deane and E. F. Garman
Identifying and quantifying radiation damage at the atomic level
J. Synchrotron Rad. (2015) 22, 201-212.
E. F. Garman and M. Weik
Radiation Damage in Macromolecule Crystallography
Synchrotron Radiation News (2015) 28, 15-19.
C. Bury, E. F. Garman, H. M. Ginn, R. B. G. Ravelli, I. Carmichael, G. Kneale and J. E. McGeehan
Radiation damage to nucleoprotein complexes in macromolecular crystallography J. Synchrotron Rad. (2015) 22, 213-224.
E. F. Garman and M. Weik
Radiation damage to macromolecules: kill or cure?
J. Synchrotron Rad. (2015) 22, 195-200.
Elspeth F. Garman
Antiviral adhesion molecular mechanisms for influenza: W.G. Laver’s lifetime obsession.
Phil. Trans. R. Soc. B (2015)  London, Ser. B  370 2014003.


Shee Chien Yong, Pietro Roversi, James Lillington, Fernanda Rodriguez, Martin Krehenbrink, Oliver B. Zeldin, Elspeth F. Garman, Susan M. Lea, Ben C. Berks
A complex iron-calcium cofactor catalyzing phosphotransfer chemistry
Science (2014) 345 (6201): 1170-1173.
Geoffrey G. Hesketh, Inmaculada Pérez-Dorado, Lauren P. Jackson, Lena Wartosch, Ingmar B. Schäfer, Sally R. Gray, Airlie J. McCoy, Oliver B. Zeldin, Elspeth F. Garman, Michael E. Harbour, Philip R. Evans, Matthew N.J. Seaman, J. Paul Luzio, David J. Owen
VARP Is Recruited on to Endosomes by Direct Interaction with Retromer, Where Together They Function in Export to the Cell Surface
Developmental Cell (2014) 29, 591-606.

Open access. Available here

Elspeth F. Garman
Developments in X-ray Crystallographic Structure Determination of Biological Macromolecules
Science (2014) 34, 1102-1108
For link to the full text click here
For link to the full text as a pdf click here.


Oliver B. Zeldin, Sandor Brockhauser, John Bembridge, James M.Holton and Elspeth F. Garman
Predicting the X-ray lifetime of protein crystals
PNAS (2013), on-line 2/12/13 here:
Oliver B. Zeldin, Markus Gerstel and Elspeth Garman
RADDOSE-3D: time- and space-resolved modeling of dose in macromolecular crystallography
J. Appl. Cryst. (2013) 46, 1225-1230.
Kristin A.  Sutton, Paul Black, Kermit R.Mercer, Elspeth F. Garman, Robin L. Owen, Edward H. Snell and William A. Bernhard
Insights into the mechanism of X-ray induced disulfide bond cleavage in lysozyme crystals based on EPR, optical absorption, and X-ray diffraction studies
Acta Cryst. D (2013) 69, 2381-2394.
Elspeth F. Garman.
Radiation Damage in Macromolecular Crystallography: What Is It and Why Do We Care?
Methods for Biomolecular Crystallography NATO Science for Peace and Security Series A: Chemistry and Biology 2013, pp 69-77.
Areej Abuhammad, Edward D. Lowe, Michael A. McDonough, Patrick D. Shaw Stewart, Stefan A. Kolek, Edith Sim, Elspeth F. Garman.
Structure of arylamine N-acetyltransferase from M. tuberculosis determined by cross-seeding with homologous protein from M. marinum: Triumph over Adversity.
Acta Cryst. D (2013) 69, 1433-1446.
Oliver B. Zeldin, Markus Gerstel and Elspeth F. Garman
Optimizing the spatial distribution of dose in X-ray macromolecular crystallography
J. Synchrotron Rad. (2013) 20, 49-57.
Elizabeth G. Allan, Melissa C. Kander, Ian Carmichael and Elspeth F. Garman
To scavenge or not to scavenge, that is STILL the question
J. Synchrotron Rad. (2013) 20, 23-36.
Elspeth F. Garman and Martin Weik
Radiation damage to biological macromolecules: some answers and more questions
J. Synchrotron Rad. (2013) 20, 1-6.
Elspeth F. Garman and Oliver B. Zeldin
Elemental Analysis of Proteins by Proton Induced X-ray Emission (microPIXE)
Advancing Methods for Biomolecular Crystallography NATO Science for Peace and Security Series A: Chemistry and Biology 2013, pp 79-89.


Areej Abuhammad, Elizabeth Fullam, Edward D. Lowe, David Staunton, Akane Kawamura, Isaac M. Westwood, Sanjib Bhakta, Alun C. Garner, David L. Wilson, Peter T. Seden, Stephen G. Davies, Angela J. Russell, Elspeth F. Garman and Edith Sim
Piperidinols That Show Anti-Tubercular Activity as Inhibitors of Arylamine N-Acetyltransferase: An Essential Enzyme for Mycobacterial Survival Inside Macrophages
PLoS ONE 7(12): e52790.
Elspeth F Garman.
Radiation Damage
International Tables for Crystallography (2012) Volume F. (Ch. 10.3 pp. 256-261)
Eugenio De la Mora, Janet Lovett, Christopher Blanford, Elspeth F. Garman, Brenda Valderrama and Enrique Rudiño-Piñera.
Structural changes caused by radiation-induced reduction and radiolysis: the effect of X-ray absorbed dose in a fungal multicopper oxidase
Acta Cryst. (2012) D68, 564-577.
Henning O. Sørensen, Søren Schmidt, Jonathan P. Wright, Gavin B. M. Vaughan, Simone Techert, Elspeth F. Garman, Jette Oddershede, Jav Davaasambu, Karthik S. Paithankar, Carsten Gundlach and Henning F. Poulsen
Multigrain crystallography
Z. Kristallogr. (2012) 227, 63–78.


Karthik S. Paithankar, Henning O. Sørensen, Jonathan P. Wright, Søren Schmidt, Henning F. Poulsen and Elspeth F. Garman
Simultaneous X-ray diffraction from multiple single crystals of Macromolecules
Acta Cryst. (2011) D67, 608–618.
Elspeth F. Garman and M. Weik
Macromolecular crystallography radiation damage research: what's new?
J. Synchrotron Rad. (2011) 18, 313-317
Eugenio De la Mora, Ian Carmichael and Elspeth F. Garman
Effective scavenging at cryotemperatures: further increasing the dose tolerance of protein crystals.
J. Synchrotron Rad. (2011) 18, 346-357


Areej M. Abuhammad, Edward D. Lowe, Elizabeth Fullam, Martin Noble, Elspeth F. Garman and Edith Sim
Probing the architecture of the Mycobacterium marinum Arylamine N-Acetyltransferase active site
Protein and Cell (2010) 1(4) 384-392.
Elspeth F Garman, Arwen R Pearson and Clemens Vonrhein
Experimental Phasing and Radiation Damage
Acta Cryst. (2010) D66, Preface to Issue.
Elspeth F. Garman
Radiation damage in macromolecular crystallography: what is it and why should we care?
Acta Cryst. (2010) D66, 339-351.
Karthik S. Paithankar and Elspeth F. Garman
Know your dose: RADDOSE
Acta Cryst. (2010). D66, 381-388.


Robin L. Owen, James M. Holton, Clemens Schulze-Briese and Elspeth F. Garman.
Response to Krumrey's Comments on 'Determination of X-ray flux using silicon pin diodes by Robin L. Owen, James M. Holton, Clemens Schulze-Briese, & Elspeth F. Garman. Journal of Synchrotron Radiation (2009) 16, 143-151'.
J. Synchrotron Rad. (2009) 16, 691-692.
Elspeth F. Garman and Colin Nave
Radiation Damage in Protein Crystals Examined Under Various Conditions by Different Methods
J. Synchrotron Rad. (2009) 16, 129-132
Robin L. Owen, James M. Holton, Clemens Schulze-Briese, and Elspeth F. Garman
Determination of X-ray flux using silicon pin diodes
J. Synchrotron Rad. (2009) 16, 143-151
Karthik S. Paithankar, Robin Leslie Owen, Elspeth F. Garman
Absorbed dose calculations for macromolecular crystals: improvements to RADDOSE
J. Synchrotron Rad. (2009) 16, 152-162
John McGeehan, Raimond B.G. Ravelli, James W. Murray, Robin Leslie Owen, Florent Cipriani, Sean McSweeney, Martin Weik, Elspeth F. Garman
Colouring Cryo-Cooled Crystals: on-line microspectrophotometry
J. Synchrotron Rad. (2009) 16, 163-172
Adam I. Barker, Robert J. Southworth-Davies, Karthik S. Paithankar, Ian Carmichael and Elspeth F. Garman
Room temperature scavengers for MX: increased lifetimes and modified dose dependence of the intensity decay
J. Synchrotron Rad. (2009) 16, 205-216
Véronique Sauvé, Pietro Roversi, Kirstin J. Leath, Elspeth F. Garman, Robin Antrobus, Susan M. Lea, and Ben C. Berks
Mechanism for the Hydrolysis of a Sulfur-Sulfur Bond Based on the Crystal Structure of the Thiosulfohydrolase SoxB
J. Biol. Chem. (2009) 284, 21707-21718
Elspeth Garman
Crystal handling for cryogenic data collection
Crystallisation of Proteins: Techniques, strategies and Tips. A LaboratoryManual.
Editor Terese Bergfors. Publisher: International University Line, La Jolla, U.S.A. 1999
ISBN 0-9636817-5-3.


Simon C Willies, Michael N, Isupov, Elspeth F. Garman, Jennifer A. Littlechild
The binding of haem and zinc in the 1.9 Å X-ray structure of Escherichia coli bacterioferritin
Journal Biological Inorganic Chemistry (2009) e-pub 2008, 14(2), 201-207
Daniel J. Koslover, Anastasia J. Callaghan, MariaJose Marcaida, Elspeth F. Garman, Monika Martick, William G .Scott and Ben Luisi
The crystal structure of the Escherichia coli RNase apoprotein and a mechanism for RNA degradation.
Structure (2008) 16, 1238-1244
Richard J. Bingham, Enrique Rudiño-Piñera, Nicola A.G. Meenan, Ulrich Schwarz-Linek, Johan P. Turkenburg, Magnus Höök, Elspeth F. Garman and Jennifer R. Potts
Crystal structures of fibronectin-binding sites from Staphylococcus aureus FnBPA in complex with fibronectin domains.
Proc. Nat. Acad. Sci(2008) 105, 12254-12258
Elspeth Garman
Macromolecular cryo-crystallography
Evolving Methods for Macromolecular Crystallography: The Structural Path to the Understanding of the Mechanism of Action of CBRN Agents (NATO Science Series II: Mathematics, Physics and Chemistry)
Editors: Randy J. Read, Joel L. Sussman.Publisher: Springer, March 1, 2008
ISBN 1402063156.


Robert J. Southworth-Davies, Melissa A. Medina, Ian Carmichael and Elspeth F. Garman
Observation of Decreased Radiation Damage at Higher Dose Rates in Room Temperature Protein Crystallography
Structure (2007) 15, 1531-1541
Enrique Rudiño-Piñera, Raimond B.G. Ravelli, George M. Sheldrick, Max H. Nanao, Vladimir V. Korostelev, Joern M. Werner, Ulrich Schwarz-Linek, Jennifer R. Potts and Elspeth F. Garman
The solution and crystal structures of a module pair from the Staphylococcus aureus-binding site of human fibronectin - a tale with a twist
JMB (2007) 368, 833-844
Will A Stanley, Niko Pursiainen, Elspeth F Garman, Andre Juffer, Matthias Wilmanns and Petri Kursula
A previously unobserved conformation for the human Pex5p receptor suggests roles for intrinsic flexibility and rigid domain motions in ligand binding
BMC Structural Biology (2007) 7, 24-36
Elspeth F. Garman and Sean McSweeney
Progress in research into radiation damage in cryo-cooled macromolecular crystals
J. Synchrotron Rad. (2007) 14, 1-3
Robert J. Southworth-Davies and Elspeth F. Garman
Radioprotectant screening for cryocrystallography.
J. Synchrotron Rad. (2007) 14, 73-83
Elspeth Garman and Robert Sweet
X-ray data collection from macromolecular crystals
Methods in Molecular Biology.
Editor Sylvie Doublié.
The Humana Press, NJ, USA. pages 63-94 (2007)
Elspeth Garman and Robin Owen
Cryocrystallography: practice and optimisation.
Methods in Molecular Biology.
Editor Sylvie Doublié.
The Humana Press, NJ, USA. pages 1-18 (2007)
Debora Lucarelli, Santina Russo, Elspeth Garman, Wolfram Meyer-Klaucke and Ehmke Pohl
Crystal Structure and Function of the Zinc Uptake Regulator FurB from Mycobacterium tuberculosis
JBC (2007) 282, 9914-9922
Elspeth F. Garman
Macromolecular Cryo-crystallography
Editors R.J. Read and J.L. Sussman
Evolving Methods for Macromolecular Crystallography, 25-40. 2007.  Springer.
Robert J Southworth-Davies, Andy Scothern, Kirstin Leath, Geoff W.Grime and Elspeth Garman
The identification of a new contaminant-free sample support film for microPIXE analysis.
Proceedings of the 11th International Conference on Particle Induced X-ray Emission and its Analytical Applications ISBN 9789703251155 Eds. J.Miranda, J.L.Ruvalcaba-Sil and OG. De Lucio, Published by UNAM, Mexico 2007


Tobias Karlberg, Ulrika Schagerlöf, Oleksandr Gakh, Sungjo Park, Ulf Ryde, Martin Lindahl, Kirstin Leath, Elspeth Garman, Grazia Isaya and Salam Al-Karadaghi
The Structure of Frataxin Oligomers Reveal the Mechanism for the Delivery and Detoxification of Iron.
Structure (2006) 14, 1535-1546
Elspeth Garman
Tailor made drugs, if used wisely, will save lives
Commentary, London Evening Standard 24/2/06
Raimond B.G. Ravelli and Elspeth F. Garman
Radiation damage in macromolecular cryocrystallography
Current Opinion of Structural Biology (2006) 16, 624-629
Cyril Boyault, Benoit Gilquuin, Yu Zhang, Vladimir Rybin, Elspeth Garman, Wolfram Meyer-Klaucke, Patrick Matthias, Christoph Mueller, and Saadi Khochbin.
HDAC6-p97/VCP controlled polyubiquitin chain turover.
EMBO Journal (2006), 1-10.
James C Analytis, Arzhang Ardevan, Stephen J.Blundell, Robin Leslie Owen, Elspeth F .Garman, Chris Jeynes and Ben J.Powell.
The effect of irradiation-induced disorder on the conductivity and critical temperature of the organic superconductor .-(BEDT-TTF)2 Cu(SCN)2.
Phys Rev Letts. (2006) 96,177002.
Robin Leslie Owen, Enrique Rudiño-Piñera, Elspeth F. Garman.
Experimental determination of the radiation dose limit for cryocooled protein crystals.
PNAS (2006) 103, 4912-4917.
Elspeth Garman and Robin Leslie Owen.
Cryo-cooling and radiation damage in macromolecular crystallography.
Acta Cryst D (2006) 62, 32-47.


Elspeth F. Garman.
SARS proteomics reveals viral secrets.
Structure (2005) 11, 1582-1583.
A. Callaghan, Y. Redko, L. M. Murphy, G. Grossmann, D. Yates, E. Garman, L. L. Ileg, C. V. Robinson, M. F. Symmons, K. J. McDowall and B. Luisi.
"Zn-link": A metal-sharing interface that organizes the quaternarystructure and catalytic site of the endoribonuclease, RNase E.
Biochemistry. (2005) 44, 4667-4675.
Colin Nave and Elspeth Garman.
Towards an understanding of radiation damage in Cryo-cooled crystals.
JSR (2005), 12, 257-260.
James Murray, Enrique Rudiño-Piñera, Robin Owen, Martin Gringinge, Raimond Ravelli and Elspeth Garman.
Parameters affecting the X-ray dose absorbed by macromolecular crystals.
JSR (2005), 12, 268-275.
Robin Leslie Owen and Elspeth Garman.
A new method for predetermining the diffraction quality of protein crystals:using SOAP as a selection tool
Acta Cryst. D (2005) 61, 130-140.
Elspeth Garman and Geoff Grime.
Elemental analysis of proteins by microPIXE.
Progress in Biophysics and Molecular Biology. (2005) 89/2, 173-205.
Elspeth Garman and Graeme Laver.
The Structure, function and inhibition of influenza virus neuraminidase.
Chapter in 'Viral Membrane Proteins: Structure, Function and Drug Design.'
Edited by Wolfgang Fischer.
Kluwer Academic/Plenum Publishers. (2005) Pages 247-267


Robin Leslie Owen, Mice Pritchard and Elspeth Garman.
Temperature Characteristics of crystal storage devices in a CP100 dry shipping Dewar.
J. Appl. Cryst. (2004) 37, 1000-1003.
Enrique Rudiño-Piñera, Uli Schwarz-Linek, Jen Potts and Elspeth Garman
Twinned or not twinned, that is the question: crystallisation and preliminary crystallgraphic analysis of the 2F13F1 module pair of human fibronectin.
Acta D (2004) 60, 1341-1345.
James Murray, Elspeth Garman and Raimond Ravelli.
X-ray absorption by macromolecular crystals: the effects of wavelength andcrystal composition on absorbed dose.
J. Appl. Cryst. (2004) 37, 513-522.
Paul H. Backe, Raimond B.G. Ravelli, Elspeth Garman and Stephen Cusack.
Crystallisation, microPIXE and preliminary crystallographic ananlysis of thecomplex between the third KH domain of hnRNP K and single stranded DNA.
Acta D (2004) 60, 784-787
Elspeth Garman and Graeme Laver.
Controlling Influenza by Inhibiting the Virus's Neuraminidase.
Current Drug Targets (2004) 5
Florence Vincent, David Yates, Elspeth Garman, Gideon Davies and James Brannigan
The three-dimensional structure of the N-Acetylglucosamine-6-phosphate Decetylase, NagA, from Bacillus subtilis
Journal of Biological Chemistry 279, 4, 2809-2816
D. Yates, E.F. Garman, N. Gemmell, I. Gomez-Morilla, G.W. Grime.
Characterisation Of Thin Support Films For MicroPIXE Analysis Of Metals In iological Materials
Proceedings ofthe 10th International Conference on Particle Induced X-ray Emission and itsAnalytical Applications ISBN 9616303627
Ed. Milos Budnar, Publishedby Institute Josef Stefan, Ljubljana, Slovenia. 2004.pdf
G.W. Grime, I. Gomez-Morilla, D. Yates, E.F. Garman.
PIXE analysis of single atoms: measuring metal atom concentrations in protein molecules
In 'Proceedings ofthe 10th International Conference on Particle Induced X-ray Emission and itsAnalytical Applications' ISBN 9616303627
Ed. Milos Budnar, Publishedby Institute Josef Stefan, Ljubljana, Slovenia. 2004.pdf


Elspeth Garman.
'Cool crystals': Cryocrystallography and Radiation Damage.
Current Opinion of Structural Biology 9, 545-551.
Elspeth Garman and James Murray.
Heavy-atom derivatisation.
Acta Cryst. D 59, 1903-1913.
Ehmke Pohl, Jon C. Haller, Ana Mijovilovich, Wolfram Meyer-Klaucke, Elspeth Garman and Michael Vasil.
Architecture of a protein central to iron homeostatis: crystal structure and spectroscopic analysis of the ferric uptake regulator.
Molecular Microbiology 47 903-915.
Garman, E.F. and Doublie, S.
Cryocooling of Macromolecular Crystals: Optimisation Methods.
Methods in Enzymology (2003) 368, 188-216.
Eva Scheuring Vanamee, Pei-chung Hseih, Zhenyu Zhu, David Yates, Elspeth Garman, Shuang-yong Xu and Aneel Aggarwal.
Glucocorticoid-like Zn(Cys)4 Zn motifs in BslI restriction endonuclease.
J. Mol. Biol. 334, 595-603.


Murray, J.M. and Garman, E.F.
Investigation of Possible Free Radical Scavengers and Metrics for Radiation Damage in Protein Crystallography.
Journal of Synchrotron Radiation 9, 347-354.
O Neill, P., Stevens, D.L. and Garman, E.F.
Physical and chemical considerations of damage induced in protein crystals bysynchrotron radiation: a radiation chemical perspective.
Journal of Synchrotron Radiation 9, 329-332.
Elspeth Garman and Colin Nave.
Radiation damage to crystalline biological molecules: current view.
Journal of Synchrotron Radiation 9, 327-328.
Laver, W.G. and Garman, E.F.
Pandemic influenza: its origin and control.
Microbes and Infection 4,1309-1316.
Timothy M.McPhillips, Scott E.McPhillips, Hsiu Ju Chiu, Aina E.Cohen, Ashley M.Deacon, Paul J.Ellis, Elspeth Garman, Ana Gonzalez, NicholasK.Sauter, R.Paul Phizackerley, S. Michael Soltis and Peter Kuhn.
Blu-Ice and the Distribution Control System: software for data acquisition andinstrument control at macromolecular crystallography beamlines.
Journal of Synchrotron Radiation (2002) bf 9, 401-406.


James Nicholson, Colin Nave, Khalid Fayz, Barry Fell and Elspeth Garman.
Modelling heating effects in cryocooled protein crystals
Nuc.Instr, Meth in physics research A 467-468 1380-1383pdf
W.G.Laver and Elspeth Garman.
The Origin and Control of Pandemic Influenza.
Science 293, 1776-1777.pdf
Andrea Szilagyi, Minakshi Ghosh, Elspeth Garman, Maria Vas
MgADP and 3-Phospholglycerate in open confirmation: New insight into the roleof the nucleotide in domain closure.
J. Mol. Biol 306, 499-511pdf
Elspeth Garman.
Macromolecular Cryo-crystallography.
in Methods inMacromolecular Crystallography, D.Turk and L.Johnson (Eds) Nato Science Series.IOS Press 2001. Pages 15-25.


Norica Branza-Nichita, Gabriela Negroiu, Andrei Petrescu, Elspeth Garman, Fran Platt, Mark Wormald, Raymond Dwek, Stefana Petrescu
Mutations at critical N-Glycosolation sites reduce tyrosinase activity byaltering folding and quality control
JBC, 275, 8169-9175pdf
Mathew Bennett, Alexander Krah, Frank Wien, Elspeth Garman, Robert McKenna, Mark Sanderson, Stephen Neidle
A DNA-porphyrin minor groove complex at atomic resolution: The structuralconsequences of porphyrin ruffling
PNAS, 97, 9476-9481pdf
Arris, C.E., Boyle, F.T., Calvert, A.H., Curtin, N.J., Endicott, J.A., Garman E.F., Gibson, A.E., Golding, B.T., Grant, S., Griffin, R.J., Jesbury, P., Johnson, L.N., Lawrie, A.M., Newell, D.R., Noble, M.E., Sausville, E.A., Schultz, R., Yu,W.
Identification of novel purine and pyrimidine cyclin-dependant kinaseinhibitors with distinct molecular interactions and tumor cell growth inhibitorprofiles.
J.Med.Chem 43(15); 2797-2804.pdf
Peter Kuhn, Elspeth Garman, S Michael Soltis.
Limitations inMacromolecular Crystallography due to Radiation Damage.
Synchrotron Radiation Instrumentation. Proceedings of the 11th US National Conference,SLAC, 1999 Editors: P.\ Pianetta, John Arthur, Sean Brennan. ISBN1-56396-941-6. (2000) 215-218


Elspeth Garman.
Cool Data: Quantity and Quality.
Acta Cryst D. D55, 1641-1653.pdf
Elspeth Garman.
Leaving no element of doubt: analysis of proteins using microPIXE.
Structure 7, R291-299.pdf
Ed Mitchell, Peter Kuhn and Elspeth Garman.
Demystifying the Synchrotron Trip: a first time user's guide.
Structure, 7, R111-121.pdf
Geoffrey W. Grime, Eva Palsgard, Elspeth F Garman, Marta Ugarte,David Pottage and Paul Wyeth.
Recent Biomedical applications of the Oxford Scanning Proton Microprobe.
International Journal of PIXE (1999) 9 199-216.
Elspeth Garman.
Crystal handling for cryogenic data collection
Chapter 17. In second edition `Crystallisation of Proteins: Techniquesstrategies and Tips. A Laboratory Manual. Editor: Terese Bergfors. Publisher:International University Line, La Jolla, U.S.A. 1999. ISBN 0-9636817-5-3
Elspeth Garman.
Crystallisation for Cryocrystallography.
Chapter17. In `Crystallisation of Proteins: Techniques strategies and Tips. ALaboratory Manual. Publisher: International University Line, La Jolla, U.S.A.1999. ISBN 0-9636817-5-3


R.M. Esnouf, J. Ren, E.F. Garman, D.O'N.Somers, C.K. Ross, E.Y. Jones, D.K. Stammers and D.I. Stuart.
Continuous and Discontinuous Changes in the Unit Cell of HIV-1 Reverse Transcriptase Crystals on Dehydration. 
Acta Cryst. (1998) D54, 938-953.
Mary Gregoriou, Martin E.M. Noble, Kimberly A. Watson, Elspeth F. Garman, Thomas M. Krulle, Carmen de la Fuente, George W.J. Fleet, Nikos G. Oikonomakos, and Louise N. Johnson.
The structure of a glycogen phosphorylase glucopyranose spirohydantoin complex at 1.8\A resolution and 100 K: The role of the water structure and its contribution to binding. 
Protein Science (1998) 7, 915-927.


Elspeth Garman and Thomas Schneider.
Macromolecular Cryocrystallography.
J.Appl.Cryst. 30, 211-237.
Pamela A. Williams, Vilmos Fulop, Elspeth F. Garman, Neil F. W. Saunders, Stuart J. Ferguson and Janos Hadju.
Haem Ligand-Switching during catalysis in crystals of a nitrogen cycle Enzyme.
Nature (1997) 389, 406-412
Joseph Colacino, Nickolay Chirgadze, Elspeth Garman, K.Gopal Murti, Richard Loncharich, Angela Baxter, Kirk Staschke and W. Graeme Laver.
A single sequence change destabilises the influenza virus neuraminidase tetramer.
Virology (1997) 236, 66-75.
C.M. Nunn, E.F. Garman and S. Neidle. 
Crystal Structure of the DNA Decamer d(CGCAATTGCG) Complexed with the Minor Groove Binding Drug Netropsin.
Biochemistry (1997) 36, 4792-4799.
Johnson LN, Barford D, Owen DJ, Noble MEM, Garman EF
From phosphorylase to phosphorylase kinase.
Signal Transduction in Health and Disease. Corbin JD, Francis SH (eds) pp. 11-28


Elspeth Garman and Edward Mitchell.
Glycerol concentrations required for cryoprotection of 50 typical protein crystallisation solutions.
J.Appl. Cryst. 29, 584-587.
E.P.Mitchell, S.G.Withers, P.Emert, A.T.Vasella, E.F.Garman, N.G. Oikonomakos, and L.N. Johnson.
Ternary Complex Crystal Structures of Glycogen Phosphorylase with the Transition State Analogue Nojirimycin Tetrazole and Phosphate in the T and R States.
Biochemistry (1996) 35, 7341-7355.
Susan Crennell, Elspeth Garman, Graeme Laver, Eric Vimr and Garry Taylor.
The structures of Salmonella typhimurium LT2 neuraminidase and its complexes with three inhibitors at high resolution.
J. Mol. Biol. (1996) 259: 264-280.
Susan Crennell, Elspeth Garman, Graeme Laver, Eric Vimr and Garry Taylor.
The structures of Salmonella typhimurium LT2 neuraminidase and its complexes with three inhibitors at high resolution.
J. Mol. Biol. (1996) 259: 264-280.
E.F. Garman
Modern Methods for rapid X-ray diffraction data collection from crystals of macromolecules.
Ed. M.R. Sanderson. The Humana Press Inc., New Jersey, U.S.A.
Methods in Molecular Biology (1996) Volume 56, pp. 87-126 Physical Methods of Analysis.


N.Brown, M.E.M.Noble, J.A.Endicott, E.F.Garman, S.Wakatsuki, E.Mitchell, B.Rasmussen, T.Hunt and L.N.Johnson.
The structure of cyclin A contains a tandem duplication of a novel protein fold.
Structure (1995) 3, 1235-1247.
D.J.Owen, M.E.M.Noble, E.F.Garman, A.C.Papageorgiou and L.N.Johnson.
Two structures of the catalytic domain of phosphorylase kinase: an active protein kinase complexed with substrate analogue and product.
Structure (1995) 3, 467-482.
Jinshan Ren, Robert Esnouf, Elspeth Garman, Donald Somers, Carl Ross, Ian Kirby, James Keeling, Graham Darby, Yvonne Jones, David Stuart and David Stammers.
High Resolution Structures of HIV-1 RT from four RT-inhibitor complexes.
Nature Structural Biology. (1995) 2, 293-302.
J.A.Endicott, M.E.Noble, E.F.Garman, N.Brown, B.Rasmussen, P.Nurse and L.N.Johnson.
The crystal structure of P13 suc1, a p34cdc2-interacting cell cycle control protein.
EMBO Journal. (1995) 14 1004-1014.
D.J.Owen, A.C.Papageorgiou, E.F.Garman, M.E.M.Noble, and L.N.Johnson.
Expression, Purification and Crystallisation of Phosphorylase Kinase Catalytic Domain.
J. Mol. Biol. (1995) 246, 374-381.


Edward Mitchell and Elspeth Garman.
Flash Freezing of Protein crystals: Investigation of Mosaic Spread and Diffraction Limit with Variation of Cryoprotectant Concentration.
J.Appl. Cryst. 27, 1070-1074.
D.K.Stammers, D.O'N.Somers, C.K.Ross, I.Kirby, P.H.Ray, J.E.Wilson, M.Norman, J.S. Ren, R.M.Esnouf, E.F.Garman, E.Y.Jones and D.I.Stuart.
Crystals of HIV-1 Reverse Transcriptase Diffracting to 2.2Å Resolution.
J.Mol.Biol. (1994) 242, 586-588.
Susan Crennell, Elspeth Garman, Graeme Laver, Eric Vimr and Garry Taylor.
Crystal Structure of Vibrio cholerae neuraminidase reveals dual lectin-like domains in addition to the catalytic domain.
Structure (1994) 2:535-544.
Graeme Laver and Elspeth Garman.
'Flu Neuraminidase: the Virus' Achilles heel?
Science and Technology Now. Winter 1994/95. 6, 30-33.
Graeme Laver and Elspeth Garman.
'Flu Neuraminidase: the Virus' Achilles heel?
Today's Life Science (1994) 6, 40-47.
Elspeth F.Garman and W.G.Laver.
Why we keep catching the 'flu: The Origin and Control of Influenza Pandemics.
Science and Public AffairsWinter 1994. 44-48.


Susan Crennell, Elspeth Garman, Graeme Laver, Eric Vimr and Garry Taylor.
Crystal structure of a bacterial sialidase (from Salmonella typhimurium LT2) shows the same fold as an influenza neuraminidase.
Proc. Nat. Acad. Sci. (1993) 90, 9852-9856.
M.G.Pickford, E.F.Garman, E.Y.Jones and D.I.Stuart.
A design of crystal mounting cell that allows the controlled variation of humidity at the protein crystal during X-ray diffraction.
J.Appl.Cryst. (1993) 26, 465-466.
Garry Taylor, Elspeth Garman, Robert Webster, Takehiko Saito and Graeme Laver.
Crystallization and Preliminary X-ray Studies of Influenza Subtypes N5, N6, N8 and N9.
J.Mol.Biol. (1993) 230, 345-348.
E.Y.Jones, D.I.Stuart, E.F.Garman, R.Griest, D.C.Phillips, G.L.Taylor, O.Matsumoto, G.Darby, B.Larder, D.Lowe, K.Powell, D.Purifoy, C.K.Ross, D.Somers, M.Tisdale and D.K.Stammers.
The growth and characterization of crystals of immunodeficiency virus (HIV) reverse transcriptase.
Journal of Crystal Growth (1993) 126, 261-269.
Ewald Shroder, Christopher Phillips, Elspeth Garman, Karl Harlos and Catherine Crawford.
X-ray crystallographic structure of a papain-leupeptin complex.
FEBS (1993) 315, 38-42.
Ewald Shroder, Christopher Phillips, Elspeth Garman, Karl Harlos and Catherine Crawford.
X-ray crystallographic structure of a papain-leupeptin complex.
FEBS (1993) 315, 38-42.
Elspeth Garman.
Problematic data collections: give up or persist?
Data Collection and Processing, Proceedings of the CCP4 Study Weekend. DL/SCI/R34 (1993) 123-131.


Garry Taylor, Eric Vimr, Elspeth Garman, and Graeme Laver.
Purification, Crystallisation and Preliminary Crystallographic Study of Neuraminidase from Vibrio Cholerae and Salmonella Typhimurium LT2.
J. Mol. Biol. (1992) 226, 1287-1290.
David G.Brown, Mark R.Sanderson, Elspeth Garman and Stephen Neidle.
Crystal Structure of a Berenil-d(CGCAAATTTGCG) Complex; an example of Drug-DNA recognition based on Sequence-dependent structural features.
J. Mol. Biol. (1992) 226, 481-490.
Anne Cleasby, Elspeth Garman, Maarten R. Egmond and Max Batenburg.
Crystallization and Preliminary X-ray Study of a Lipase from Pseudomonas Glumae.
J.Mol.Biol. (1992) 224, 281-282.
R.W.Pickersgill, G.W.Harris and E.Garman.
Structure of Monoclinic Papain at 1.60Å Resolution.
Acta Cryst. (1992) B48, 59-67.


G.R.Clark, D.G.Brown, M.R.Sanderson, T.Chwalinski, S.Neidle, J.M.Veal, R.L.Jones, W.D.Wilson, G.Zon, E.Garman and D.I. Stuart.
Crystal and solution structures of the oligonucleotide d(ATGCGCAT)2: a combined X-ray and NMR study.
Nucleic Acid Research (1990) 18, 5521-5528.
David G.Brown, Mark R.Sanderson, Jane V.Skelly, Terence C.Jenkins, Tom Brown, Elspeth Garman, David I.Stuart, Stephen Neidle.
Crystal Structure of a Berenil-dodecanuleotide Complex: the Role of Water in Sequence Specific Ligand Binding.
EMBO Journal (1990) Vol. 9, 1329-1334.


D.K.Stammers, K.L.Powell, B.A.Larder, G.Darby, D.J.M.Purifoy, M.Tisdale, D.Lowe, D.I.Stuart, E.Y.Jones, G.Taylor, E.F.Garman, R.Greist and D.C.Phillips.
Structural Studies on HIV Reverse Transcriptase.
Ed. W.G.Laver and G.M.Air. 309-319.
Use of X-ray Crytallography in the Design of Antiviral Agents.  Proceedings of International Virology Conference,  Hawaii 1989.
J.V.Skelly, D.A.Suter, R.J.Knox, E.Garman, D.I.Stuart, M.R.Sanderson, J.J.Roberts and S.Neidle.
Preliminary Crystallographic Data for NAD(P)H Quinone Reductase Isolated from the Walker 256 Rat Carcinoma Cell Line.
J.Mol.Biol., (1989) 205, 623-624.

(Publications in the field of Nuclear Structure Physics can be found here)
























































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