Welcome to the Garman Group website
We are part of the Laboratory of Molecular Biophysics at the University of Oxford.
Our research focuses on developing methods for macromolecular crystallography (MX) to enable problems not previously accessible to structure solution to be tackled. This work currently includes studies on 100K and room temperature (RT) radiation damage and the analysis of liquid and crystalline samples by the tehnique of microPIXE (microbeam Proton Induced X-ray Emission). The group also solve protein structures, most recently of arylamine N-acetyltransferase from Mycobacterium tuberculosis.
For more information about the group please visit our "People" page here
Above is the cover of the special issue of the Journal of Synchrotron Radiation on X-ray Radiation Damage to Biological Crystalline Samples (March 2015). The image on the lower right shows the specific damage distribution (red and blue spheres) of the irradiated baterial protein-DNA complex CEsp1396I/DNA. The work and figure was produced by Charlie Bury.
Introduction to Crystallography
The British Crystallographic Association
The British Crystallographic Association (BCA) is the UK national association for crystallograpy. It's main aims are the promotion of crystallography in research and the education of young people and others in the methods, possibilities and achievements of crystallographic science. can visit the website here.
Special Issue of JSR - In March 2015 a special issue of the Journal of Synchrotron Radiation on X-ray Radiation Damage to Biological Crystalline Samples was published. This issue was edited by Elspeth and Martin Weik and features papers by Charlie Bury and Garman Group Alumnus Markus Gerstel.
Elspeth in puerto Rico - The BioXFEL conference took place in Puerto Rico this year and Elspeth was in attendance. She also managed to visit two crystallography students at the University of Puerto Rico.
Why Science? Why Maths? - Jonny took part in the event at Cheney School, delievering hands on crystallography activities and giving a presentation about mathematics in crystallography.
RADDOSE-3D source code released - The source code for RADDOSE-3D has now been publicly released and can be acessed on Github. Furthermore the release available on the raddo.se website has been updated with several improvments and fixes.
CCP4 Study Weekend - The Garman group attended the CCP4 study weekend which took place on the 7th -9th January on advances in experimental phasing.
Elspeth wins Humanitarian award - The Women's International Film and Television Showcase (WIFTS) has awarded Elspeth for her contributions to X-ray crystallography.
Presentation at the Royal Albert Hall - The Illuminating Atoms exhibition features photographs by Max Alexander showcasing the work of crystallographers. Elspeth featured at the event giving a talk about how crystallography has changed the world.
Publication in Science - Elspeth and Garman Group alumnus, Oliver Zeldin, are co-authors on a recent publication in Science.