Department of Biochemistry University of Oxford Department of Biochemistry
University of Oxford
South Parks Road
Oxford OX1 3QU

Tel: +44 (0)1865 613200
Fax: +44 (0)1865 613201
Anaphase bridges in fission yeast cells
Whitby lab
Lactose permease represented using bending cylinders in Bendix software
Caroline Dahl, Sansom lab
Epithelial cells in C. elegans showing a seam cell that failed to undergo cytokinesis
Serena Ding, Woollard lab
Collage of Drosophila third instar larva optic lobe
Lu Yang, Davis lab
First year Biochemistry students at a practical class
Image showing the global movement of lipids in a model planar membrane
Matthieu Chavent, Sansom lab
Bootstrap Slider

Postdoctoral Research Associate in the Functional Significance of Lipid Binding Properties of Human Notch Ligands

We are seeking to appoint a Postdoctoral Research Associate to investigate the functional role of lipid binding to canonical Notch ligands as a modulator of Notch signalling. This role will involve the expression in bacteria (and in vitro refolding) and mammalian cells (S2 and HEK) of Notch receptor and ligand proteins. You will use modern lipid/protein interaction methods to probe structure and function, as well as conventional liposome and signalling assays, and undertake biophysical analysis of protein/lipids using methods such as SPR, mass spectrometry, NMR and EM.

Applicants should possess, or expect to obtain soon, a PhD in Biochemistry, Cell Biology or a related area, with experience of working in the area of molecular and cellular characterisation of lipid binding proteins, particularly with respect to investigating lipid binding specificity. You will be familiar with recombinant protein expression and chromatography methods and have applied these methods in your research. Good written and oral communication skills are required, as you will need to keep detailed laboratory records to meet publication standards. You will be required to demonstrate competence and success in your thesis and/or postdoctoral work, and have the ability to work collaboratively and supportively in a laboratory environment, as well as contributing to supervision activities.

This full time fixed term post is funded by the MRC for up to 3 years in the first instance and is based at the Department of Biochemistry, South Parks Road, Oxford, OX1 3QU.

This position is graded on the University's Grade 7 scale, for which the salary range is £31,604 - £38,833 per annum. The actual starting salary offered will be based on qualifications and relevant skills acquired and will also be determined by the funding available.

For further general information, phone (01865) 613204, quoting reference 133226.

Applications for this vacancy are to be made online.

To apply for this role and for further details, including the job description and selection criteria,

please click on the link below:

The closing date for applications is 12.00 noon on Wednesday, 28th February 2018, with interviews for shortlisted candidates to be held as soon as possible thereafter.

The University of Oxford is a member of the Athena SWAN Charter and holds an institutional Bronze Athena SWAN award. The Department of Biochemistry is strongly committed to equality and valuing diversity and we operate a flexible working policy for all staff. The Department holds a departmental Silver Athena award in recognition of its efforts to introduce organisational and cultural practices that promote gender equality and create a better working environment for both men and women.

Committed to equality and valuing diversity.



Related Information

Share This