Alumni

Past and present: Many alumni and current members of the Garman group gather at Elspeth's birthday in September 2014. Back row from left to right: Robin Owen, Robert Southworth-Davies, Jonny Brooks-Bartlett, James Murray, Markus Gerstel. Front row from left to right Charlie Bury, Olga Kuznetsova, Elspeth Garman, Areej AbuHammad, Helen Ginn.

 

 

 

Jonathan Brooks-Bartlett (October 2013 - December 2016)

 Education: D. Phil student

Jonny's research focused on the development of computational methods to track and mathematically correct for detrimental global radiation damage effects when processing diffraction patterns that are collected during MX data collection. His research was not restricted to MX, and he also studied the effects of radiation damage in SAXS data collection, developing an open source python library 'CorMapAnalysis' to visualise the CorMap (Correlation Map) test results for SAXS data and extending the dose calculation software, RADDOSE-3D, for use in SAXS experiments.

 

Ben Gayther (June 2016 - September 2016)

 Education: Visiting BSc student (UCL)

Ben worked on implementing a photoelectron escape model into the current version of RADDOSE-3D. When incident X-ray photons interact with a crystal during crystallography experiments, each incident photon has the possibility of interacting via the photoelectric effect and producing a photoelectron. These photoelectrons are still able to move throughout the crystal even at cryo temperatures. In small crystals this effect can be used to reduce the overall radiation damage. If the photoelectron escapes out of the crystal, then the energy of this photon is deposited elsewhere and will therefore not contribute to the radiation dose in the crystal.

Shu Tsukui (March 2015 - August 2015)

Education: Visiting PhD student (Kyoto University)

Shu investigated the technique of magnetically orientating microcrystals in ultra-light curable resins to create MOMAs (magnetically orientated microcrystal arrays). His research indicated that a combination of MOMAs with conventional synchrotron beamlines could have valuable potential for crystal analyses of protein crystals that do not growto larger sizes.

Rebecca Batters (September 2014 - March 2014)

 Education: Part II student

Rebecca studied the effects of sodium nitrate as a scavenging cryoprotectant for X-ray crystallography experiments to see if it would reduce the structural damage caused by the X-rays during an X-ray crystallography experiment. Further to this Rebecca also studied the different scavenging effects of various scavenger species in small angle X-ray scattering (SAXS) experiments too.

Tom Dixon (September 2014 - March 2014)

 Education: Part II student

Tom's research was focussed on quantifying the specific radiation damage to protein molecules in X-ray crystallography experiments. In particular Tom continued work on the B-damage metric, a new metric to developed by Garman group alumnus Markus Gerstel. He adapted the metric to study progressive radiation damage between successive datasets on the same protein structure and also compared how different probing species affects the specific damage observed in protein structures.

Markus Gerstel (October 2011 - November 2014)

 Education: D. Phil student

Markus made many important contributions to the group during his time here. His research focus was on the specific structural damage that occurs to proteins during an X-ray crystallography experiment. He developed a new mtric called B-damage which allows crystallographers to evaluate the relative damage of each atom in the sample molecule taking into account variable factors such as how densely each atom is packed in the molecule. He also made significant contributions as one of the original authors of the groups dose calculation software RADDOSE-3D. Markus now works at Diamond Light Source and is involved improving data collection and analysis pipelines for crystallographic experiments.

Helen Ginn (March 2014 - December 2014)

 Education: Wellcome Trust project student

During her time in the group Helen Ginn made key developments in the groups open source dose calculation software RADDOSE-3D. In particular she wrote extensions so that simulations could be performed on crystals of arbitrary shapes, allow users to use PDB codes to define the content of their protein crystals, and translated legacy code into a single language. Helen is now working towards a D. Phil in Dave Stuart's lab developing new computational tools for processing data collected at X-ray free electron lasers (XFELs).

Oliver Starkey (Sept 2013 - March 2014)

 Education: Part II student

Whilst in the group, Oliver worked on Microbeam Proton-Induced X-ray Emission (MicroPIXE). MicroPIXE is a powerful technique that enables identification and quantification of heavy atoms in proteins by using an energetic proton beam to induce characteristic X-rays from these atoms. This complements X-ray crystallography, allowing different metal atoms to be distinguished and more accurately placed in electron density. The main aim of the project was to examine existing metalloproteins in order to validate and/or refine their PDB structures, armed with quantitative data of their metal content. Oliver made ashtonishing discoveries including some that showed that some protein structures that had been deposited in the PDB were deposited with the incorrect metal content.

Oliver B Zeldin 

Education: D. Phil student

 

 

 

Areej Abuhammed

Education: D.Phil student

 

 

 

John Bembridge

Education: Part II student

 

 

 

Young Choi

Education: Part II student

 

 

 

Robert Davies

Education: D.Phil student

 

 

 

 

 

 

Elisabeth Armstrong

Education: Part II student

 

 

 

 

 

 

Adam Barker

Education: Part II student

 

 

 

 

 

 

 

Professor John Fink

Education: BA, University of Iowa 

MS, PhD, University of Michigan

Sabbatical Visiting Maths Professor

 

 

 

 

 

 

 

Dr. Enrique Rudiño-Piñera

Education: BSc in Chemistry at Universidad La Salle-Mexico 

MSc in Biotechnology-UNAM-Mexico

PhD in Biochemical Sciences at UNAM-Mexico

 

 

 

 

 

 

Dr. James Murray

Education: BA Hons MSci in Natural Science, Emmanuel College Cambridge 

D.Phil in Molecular Biophysics at Worcester College Oxford.

 

 

 

Dr. Robin Owen

Education: MPhys in Physics at Keble College Oxford 

D.Phil in Physics at Keble College Oxford

 

 

 

 

 

 

Dr. Kirsten Leath

Education: MPhys in Physics at the University of St. Andrews 

D.Phil in Biochemistry at the University Oxford

 

 

 

Verane Achard

Education: University of Grenoble, France

 

 

 

 

 

 

 

Elodie Loisel

Education: University of Grenoble, France

 

 

 

 

 

Cécile Royal

Education: University of Grenoble, France

 

 

 

 

 

 

 

 

 

Part II Students

 

François-Xavier Gallat (2007) (summer student)

Tom McDonagh (2007) (summer student)

Andrew Gill (2006)

Melissa Medina (2006)

Verane Achard (2006) (summer student)

Elodie Loisel (2005) (summer student)

Andrew Reader (2005)

William Chao (2004) (summer student)

Cécile Royale (2004) (summer student)

Stephen Betts (2003)

Ben Hall (2002) (summer student)

David Yates (2002)

James Tichler (2002)

James Grimston (2000)

Petra Lukacik (1999)

Dimitri Karathanassis (1999) (summer student)

Paul Tunnah (1995)

 

 

 

 

 

 

 

 

 





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