Oxford University Biomembrane Structure Unit Section
The main research interests of the Watts's group focus on the study of the structure of small molecules when at their site of action in membrane-bound proteins whilst in their native, fully functional form in membranes. In addition, peptides which form channels in membranes are being studied to high resolution using solid state NMR methods. The potential for understanding how the membrane-bound targets for hormones, solutes and drugs function can be realised with this emerging technology.
The NMR Facility was opened in 1998, funded through investments by HEFCE and UK Research Councils with matching funds from instrument manufacturers. It is equipped as one of the major solid state biological NMR centres in the world and now has some of the most advanced instruments (at 200MHz, 400MHz, 500MHz and 800MHz) and support facilities anywhere world-wide for use in structural biology.