Oxford Glycobiology Institute
Institute Publications 1982-2019

OGI annual publication record

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The most recent papers, including some in press, are also available via ORA, the Oxford University Research Archive.

1982-1983-1984-1985-1986-1987-1988-1989-1990-1991-1992-1993-1994-1995-1996-1997-1998-1999-2000-2001-2002-2003-2004-2005-2006-2007-2008-2009-2010-2011-
2012-2013-2014-2015-2016-2017-2018-2019-2020-2021-2022-Bottom

    1982 - Top-Bottom

  1. Solution conformation of the biantennary N-linked oligosaccharide of human serotransferrin using 1H NMR nuclear Overhauser effect measurements.
    S.W. Homans, R.A. Dwek, D.L. Fernandes and T.W. Rademacher (1982) FEBS Letters, 150, 503-506. [Full text]

    1983 - Top-Bottom

  2. The localisation of effector sites on immunoglobulin.
    G. Burton, R.A. Dwek and J. Novotny (1983) in "Protein Conformation as an Immunological Signal", pp. 73-81, ed. F. Celada, V.N. Schumaker and E.E. Sercarz (Plenum Press, New York).
     
  3. Magnetic resonance studies on antibody combining sites.
    R.A. Dwek and R.J. Leatherbarrow (1983) Periodicum Biologorum (Zagreb), 85, Supp 2, 21-29.
     
  4. Structural and conformational analysis of immunoglobulin-derived N-linked oligosaccharides.
    T.W. Rademacher, S.W. Homans, D.L. Fernandes, R.A. Dwek, T. Mizuochi, T. Taniguchi and A. Kobata (1983) Biochem. Soc. Trans., 11, 132-134. [Full text]
     
  5. The use of two-dimensional correlated spectroscopy to obtain new assignments in the high-resolution 1H nuclear magnetic resonance spectrum of the biantennary complex oligosaccharide isolated from human serum transferrin by hydrazinolysis.
    S.W. Homans, R.A. Dwek, D.L. Fernandes and T.W. Rademacher (1983) Biochim. Biophys. Acta, 760, 256-261. [Full text]
     
  6. Neutron scattering studies of the isolated C1r2C1s2 subunit of first component of human complement in solution.
    J. Boyd, D.R. Burton, S.J. Perkins, C.L. Villiers, R.A. Dwek and G.J. Arlaud (1983) Proc. Natl. Acad. Sci. USA, 80, 3769-3773. [Full text]
     
  7. The effect of aglycosylation on the binding of mouse IgG to staphylococcal protein A.
    R.J. Leatherbarrow and R.A. Dwek (1983) FEBS Letters, 164, 227-230. [Full text]
     
  8. Solution conformation of biantennary complex type oligosaccharides: Determination of major conformers about the glycosidic linkages.
    S.W. Homans, R.A. Dwek, D.L. Fernandes and T.W. Rademacher (1983) FEBS Letters, 164, 231-235. [Full text]
     
  9. Structural, functional and conformational analysis of immunoglobulin G-derived asparagine-linked oligosaccharides.
    T.W. Rademacher and R.A. Dwek (1983) Progress in Immunology, 5, 95-112.

    1984 - Top-Bottom

  10. The analysis of coupling networks in a complex oligosaccharide mixture derived from the Fc region of rabbit immunoglobulin G using 1H-1H correlated NMR spectroscopy combined with double quantum NMR spectroscopy.
    S.W. Homans, R.A. Dwek, D.L. Fernandes and T.W. Rademacher (1984) Biochim. Biophys. Acta, 798, 78-83. [Full text]
     
  11. Binding of complement subcomponent C1q to Mouse IgG1, IgG2a and IgG2b: A novel C1q binding assay.
    R.J. Leatherbarrow and R.A. Dwek (1984) Mol. Immunol., 21, 321-327. [Full text]
     
  12. Structure-function relationship in immunoglobulins.
    R.A. Dwek, B.J. Sutton, S.J. Perkins and T.W. Rademacher (1984) Biochem. Soc. Symp., 49, 123-136.
     
  13. Neutron scattering studies of subcomponent C1q of first Component C1 of human complement and its association with subunit C1r2C1s2 within C1.
    S.J. Perkins, C.L. Villiers, G.J. Arlaud, J. Boyd, D.R. Burton, M.G. Colomb and R.A. Dwek (1984) J. Mol. Biol., 179, 547-557. [Full text]
     
  14. Multiple-step relayed correlation spectroscopy: Sequential resonance assignments in oligosaccharides.
    S.W. Homans, R.A. Dwek, D.L. Fernandes and T.W. Rademacher (1984) Proc. Natl. Acad. Sci. USA, 81, 6286-6289. [Full text]

    1985 - Top-Bottom

  15. Effector functions of a monoclonal aglycosylated Mouse IgG2a: Binding and activation of complement component C1 and interaction with human monocyte Fc receptor.
    R.J. Leatherbarrow, T.W. Rademacher, R.A. Dwek, J.M. Woof, A. Clark, D.R. Burton, N. Richardson and A. Feinstein (1985) Mol. Immunol., 22, 407-415. [Full text]
     
  16. Association of rheumatoid arthritis and primary osteoarthritis with changes in the glycosylation pattern of total serum IgG.
    R.B. Parekh, R.A. Dwek, B.J. Sutton, D.L. Fernandes, A. Leung, D. Stanworth, T.W. Rademacher, T. Mizuochi, T. Taniguchi, K. Matsuta, F. Takeuchi, Y. Nagano, T. Miyamoto and A. Kobata (1985) Nature, 316, 452-457. [Full text]
     
  17. Structures of the sugar chains of rabbit immunoglobulin G: Occurrence of asparagine-linked sugar chains in Fab fragment.
    T. Taniguchi, T. Mizuochi, M. Beale, R.A. Dwek, T.W. Rademacher and A. Kobata (1985) Biochemistry, 24, 5551-5557. [Full text]
     
  18. Immunoglobulin G as a glycoprotein.
    T.W. Rademacher, S.W. Homans, R.B. Parekh and R.A. Dwek (1985) Biochem. Soc. Symp., 51, 131-148.

    1986 - Top-Bottom

  19. Conformational transitions in N-linked oligosaccharides.
    S.W. Homans, R.A. Dwek, J. Boyd, M. Mahmoudian, W.G. Richards and T.W. Rademacher (1986) Biochemistry, 25, 6342-6350. [Full text]
     
  20. Synthesis of 2-Acetamido-1,5-imino-1,2,5-trideoxy-D-mannitol and of 2-Acetamido-1,5-imino-1,2,5-trideoxy-D-glucitol, a potent and specific inhibitor of a number of b-N-Acetylglucosamindases.
    G.W.J. Fleet, P.W. Smith, R.J. Nash, L.E. Fellows, R.B. Parekh and T.W. Rademacher (1986) Chemistry Letters, 7, 1051-1054. [Full text]

    1987 - Top-Bottom

  21. A method for the rapid assignment of 1H NMR spectra of oligosaccharides using homonuclear Hartmann-Hahn spectroscopy.
    S.W. Homans, R.A. Dwek, J. Boyd, N. Soffe and T.W. Rademacher (1987) Proc. Natl. Acad. Sci. USA, 84, 1202-1205. [Full text]
     
  22. Tissue-specific N-glycosylation, site-specific oligosaccharide patterns and lentil lectin recognition of rat Thy-1.
    R.B. Parekh, A.G.C. Tse, R.A. Dwek, A.F. Williams and T.W. Rademacher (1987) EMBO J., 6, 1233-1244. [Full text]
     
  23. The b1-2-D-xylose and a1-3-L-fucose substituted N-linked oligosaccharides from Erythrina cristagalli lectin. Isolation, characterization and comparison with other legume lectins.
    D.A. Ashford, R.A. Dwek, J.K. Welply, S. Amatayakul, S.W. Homans, H. Lis, G.N. Taylor, N. Sharon and T.W. Rademacher (1987) Eur. J. Biochem., 166, 311-320. [Full text]
     
  24. Identification of phosphorylated 3-deoxy-manno-octulosonic acid as a component of Haemophilus influenzae lipopolysaccharide.
    S.E. Zamze, M.A.J. Ferguson, E.R. Moxon, R.A. Dwek and T.W. Rademacher (1987) Biochem. J., 245, 583-587. [Full text]
     
  25. Structural studies on the glycophospholipid membrane anchor of Trypanosoma brucei variant surface glycoprotein.
    M.A.J. Ferguson, R.A. Dwek, S.W. Homans and T.W. Rademacher (1987) in "NATO/ASI. Volume: H11 Host-Parasite Cellular and Molecular Interaction in Protozoal Infections", pp. 19-28, ed. K.P. Chang and D. Snary.
     
  26. Tertiary structure in N-linked oligosaccharides.
    S.W. Homans, R.A. Dwek and T.W. Rademacher (1987) Biochemistry, 26, 6553-6560. [Full text]
     
  27. Structure and dynamics in oligomannose-type oligosaccharides.
    S.W. Homans, A. Pastore, R.A. Dwek and T.W. Rademacher (1987) Biochemistry, 26, 6649-6655. [Full text]
     
  28. Solution conformations of N-linked oligosaccharides.
    S.W. Homans, R.A. Dwek and T.W. Rademacher (1987) Biochemistry, 26, 6571-6578. [Full text]
     
  29. Structure of the major carbohydrate fragment of the Leishmania donovani lipophosphoglycan.
    S.J. Turco, S.R. Hull, P.A. Orlandi Jr, S.D. Shepherd, S.W. Homans, R.A. Dwek and T.W. Rademacher (1987) Biochemistry, 26, 6233-6238. [Full text]
     
  30. Oligosaccharide conformation.
    C.J. Edge, S.W. Homans, R.A. Dwek and T.W. Rademacher (1987) in "Fourth European Seminar and Exhibition on Computer-Aided Molecular Design" (IBC Technical Services Ltd).

    1988 - Top-Bottom

  31. The glycosylphosphatidylinositol membrane anchor of Trypanosoma brucei variant surface glycoprotein.
    M.A.J. Ferguson, S.W. Homans, R.A. Dwek and T.W. Rademacher (1988) Biochem. Soc. Trans., 16, 265-268. [Full text]
     
  32. Age-related galactoyslation of N-linked oligosaccharides of human serum IgG.
    R.B. Parekh, I.M. Roitt, D.A. Isenberg, R.A. Dwek and T.W. Rademacher (1988) J. Exp. Med., 167, 1731-1736. [Full text]
     
  33. Galactosylation of IgG associated oligosaccharides: Reduction in patients with adult and juvenile onset rheumatoid arthritis and relation to disease activity.
    R.B. Parekh, D.A. Isenberg, B.M. Ansell, I.M. Roitt, R.A. Dwek and T.W. Rademacher (1988) Lancet, 331, 966-969. [Full text]
     
  34. Glycosyl-phosphatidylinositol moiety that anchors Trypanosoma brucei variant surface glycoprotein to the membrane.
    M.A.J. Ferguson, S.W. Homans, R.A. Dwek and T.W. Rademacher (1988) Science, 239, 753-759. [Full text]
     
  35. Glycobiology.
    T.W. Rademacher, R.B. Parekh and R.A. Dwek (1988) Ann. Rev. Biochem., 57, 785-838. [Full text]
     
  36. Rheumatoid arthritis as a glycosylation disorder.
    R.B. Parekh, R.A. Dwek and T.W. Rademacher (1988) British Journal of Rheumatology, 27 (suppl II), 162-169. [Full text]
     
  37. Identification of a monoclonal antibody to abscission tissue that recognises xylose/fucose-containing N-linked oligosaccharides from higher plants.
    M.T. McManus, J. McKeating, D.S. Secher, D.J. Osborne, D.A. Ashford, R.A. Dwek and T.W. Rademacher (1988) Planta, 175, 506-512. [Full text]
     
  38. d-Lactams: Synthesis from D-glucose, and preliminary evaluation as a fucosidase inhibitor of L-Fuconic-d-lactam.
    G.W.J. Fleet, N.G. Ramsden, R.A. Dwek, T.W. Rademacher, L.E. Fellows, R.J. Nash, D.St.C. Green and B. Winchester (1988) J. Chem. Soc. Chem. Comm., issue 7, 483-485. [Full text]
     
  39. The role of IgG glycoforms in the pathogenesis of rheumatoid arthritis.
    T.W. Rademacher, R.B. Parekh, R.A. Dwek, D.A. Isenberg, G. Rook, J.S. Axford and I. Roitt (1988) Springer Seminars in Immunopathology, 10, 231-249. [Full text]
     
  40. Complete structure of the glycosylphosphatidylinositol membrane anchor of rat brain Thy-1 glycoprotein.
    S.W. Homans, M.A.J. Ferguson, R.A. Dwek, T.W. Rademacher, R. Anand and A.F. Williams (1988) Nature, 333, 269-272. [Full text]
     
  41. Characterisation of the cross-reacting determinant (CRD) of the glycosyl-phosphatidylinositol membrane anchor of Trypanosoma brucei variant surface glycoprotein.
    S.E. Zamze, M.A.J. Ferguson, R. Collins, R.A. Dwek and T.W. Rademacher (1988) Eur. J. Biochem., 176, 527-534. [Full text]
     
  42. Galactose residues in chronic inflammatory disease - reply.
    J.S. Axford, F.C. Hay, L. Mackenzie, D.A. Isenberg, P.M. Lydyard, I.M. Roitt, G. Rook, T.W. Rademacher, R.B. Parekh and R.A. Dwek (1988) Lancet, 331, 418. [Full text]
     
  43. Galactosylation of IgG associated oligosaccharides.
    D.A. Isenberg, J.S. Axford, P.M. Lydyard, F.C. Hay, G.W. Rook, I.M. Roitt, N. Sumar, R.B. Parekh, R.A. Dwek and T.W. Rademacher (1988) Lancet, 332, 288. [Full text]
     
  44. The role of antigen in autoimmune responses with special reference to changes in carbohydrate structure of IgG in rheumatoid arthritis.
    I.M. Roitt, R.A. Dwek, R.B. Parekh, T.W. Rademacher, A. Alavi, J.S. Axford, K.B. Bodman, A. Bond, A. Cooke, F.C. Hay, D.A. Isenberg, P.M. Lydyard, L. MacKenzie, G. Rook, M. Smith and N. Sumar (1988) J. Autoimmunity, 1, 499-506. [Full text]
     
  45. Changes in carbohydrate structure of IgG in rheumatoid arthritis.
    I.M. Roitt, R.A. Dwek, R.B. Parekh, T.W. Rademacher, A. Alavi, J.S. Axford, K.B. Bodman, A. Bond, A. Cooke, F.C. Hay, D.A. Isenberg, P.M. Lydyard, L. MacKenzie, G. Rook, M. Smith and N. Sumar (1988) Recenti Progressi in Medicini, 79, 314-317.
     
  46. The Thy-1 glycoprotein: a three-dimensional model.
    S.J. Perkins, A.F. WIlliams, T.W. Rademacher and R.A. Dwek (1988) TIBS, 13, 302-303. [Full text]
     
  47. Inhibition of HIV replication by amino-sugar derivatives.
    G.W.J. Fleet, A. Karpas, R.A. Dwek, L.E. Fellows, A.S. Tyms, S. Petursson, S.K. Namgoong, N.G. Ramsden, P.W. Smith, J.C. Son, F. Wilson, D.R. Witty, G.S. Jacob and T.W. Rademacher (1988) FEBS Letters, 237, 128-132. [Full text]
     
  48. Aminosugar derivatives as potential anti-human immunodeficiency virus agents.
    A. Karpas, G.W.J. Fleet, R.A. Dwek, S. Petursson, S.K. Namgoong, N.G. Ramsden, G.S. Jacob and T.W. Rademacher (1988) Proc. Natl. Acad. Sci. USA, 85, 9229-9233. [Full text]
     
  49. The role of oligosaccharides in modifying protein function.
    T.W. Rademacher and R.A. Dwek (1988) CIBA Foundation Symposia, 145, 241-256.

    1989 - Top-Bottom

  50. A comparative analysis of disease-associated changes in the galactosylation of serum IgG.
    R.B. Parekh, D.A. Isenberg, G. Rook, I. Roitt, R.A. Dwek and T.W. Rademacher (1989) J. Autoimmunity, 2, 101-114. [Full text]
     
  51. Solution structure of the glycosylphosphatidylinositol membrane anchor glycan of Trypanosoma brucei variant surface glycoprotein.
    S.W. Homans, C.J. Edge, M.A.J. Ferguson, R.A. Dwek and T.W. Rademacher (1989) Biochemistry, 28, 2881-2887. [Full text]
     
  52. Tissue specific O-linked glycosylation of the neural cell adhesion molecule (N-CAM).
    F.S. Walsh, R.B. Parekh, S.E. Moore, G. Dickson, C.H. Barton, H.J. Gower, R.A. Dwek and T.W. Rademacher (1989) Development, 105, 803-811. [Full text]
     
  53. Structure of the phosphosaccharide-inositol core of the Leishmania donovani lipophosphoglycan.
    S.J. Turco, P.A. Orlandi Jr, S.W. Homans, M.A.J. Ferguson, R.A. Dwek and T.W. Rademacher (1989) J. Biol. Chem., 264, 6711-6715. [Full text]
     
  54. Structure function studies on Leishmania surface membrane protein.
    R.W. Olafson, R.A. Dwek, T.W. Rademacher, K.P. Chang and M.A.J. Ferguson (1989) in "Leishmaniaisis: Current Status and New Strategies for Control", ed. D.T. Hart (Plenum Press, New York).
     
  55. N-glycosylation and the production of recombinant glycoproteins.
    R.B. Parekh, R.A. Dwek, C.J. Edge and T.W. Rademacher (1989) Trends in Biotechnology, 7, 117-122. [Full text]
     
  56. Short efficient synthesis of the a-L-Fucosidase inhibitor, deoxyfuconojirimycin [1-5-Dideoxy-1,5-imino-L-fucitol] from D-Lyxonolactone.
    G.W.J. Fleet, S. Petursson, A. Campbell, R.A. Mueller, J.R. Behling, K.A. Babiak, J.S. Ng and M.G. Scaros (1989) J. Chem. Soc. Perkin Trans. I, 665-666. [Full text]
     
  57. Cell-type-specific and site-specific N-glycosylation of type I and type II human tissue plasminogen activator.
    R.B. Parekh, R.A. Dwek, J.R. Thomas, T.W. Rademacher, G. Opdenakker, A.J. Wittwer, S.C. Howard, R. Nelson, N.R. Siegel, M.G. Jennings, N.K. Harakas and J. Feder (1989) Biochemistry, 28, 7644-7662. [Full text]
     
  58. Effects of N-glycosylation on in vitro activity of Bowes melanoma and human colon fibroblast-derived tissue plasminogen activator.
    A.J. Wittwer, S.C. Howard, L.S. Carr, N.K. Harakas, J. Feder, R.B. Parekh, P.M. Rudd, R.A. Dwek and T.W. Rademacher (1989) Biochemistry, 28, 7662-7669. [Full text]
     
  59. N-glycosylation and in vitro enzymatic activity of human recombinant tissue plasminogen activator expressed in chinese hamster ovary Cells and a murine cell line.
    R.B. Parekh, R.A. Dwek, P.M. Rudd, J.R. Thomas, T.W. Rademacher, T. Warren, T.C. Wun, B. Hebert, B. Reitz, M. Palmier, T. Ramabhadran and D.C. Tiemeier (1989) Biochemistry, 28, 7670-7679. [Full text]
     
  60. O-Linked oligosaccharides from human serum immunoglobulin A1.
    M.C. Field, R.A. Dwek and T.W. Rademacher (1989) Biochem. Soc. Trans., 17, 1034-1035. [Full text]
     
  61. A transient rise in agalactosyl IgG correlating with free interleukin 2 receptors, during episodes of erythema nodosum leprosum.
    E. Filley, A. Andreoli, J. Steele, M. Waters, D. Wagner, D. Nelson, K. Tung, T.W. Rademacher, R.A. Dwek and G.A.W. Rook (1989) Clin. Exp. Immunol., 76, 343-7 [Full text]

    1990 - Top-Bottom

  62. Extracting subspectra from overlapping regions. DOUBLE TOCSY.
    R. Bazzo, C.J. Edge, R.A. Dwek and T.W. Rademacher (1990) J. Magn. Reson., 86, 199-203. [Full text]
     
  63. Characterisation of the asparagine-linked oligosaccharides from Trypanosoma brucei type I variant surface glycoproteins.
    S.E. Zamze, E.W. Wooten, D.A. Ashford, M.A.J. Ferguson, R.A. Dwek and T.W. Rademacher (1990) Eur. J. Biochem., 187, 657-663. [Full text]
     
  64. 500-picosecond molecular dynamics in water of the Mana1-2Mana glycosidic linkage present in asn-linked oligomannose-type structures on glycoproteins.
    C.J. Edge, U.C. Singh, R. Bazzo, G.L. Taylor, R.A. Dwek and T.W. Rademacher (1990) Biochemistry, 29, 1971-1974. [Full text]
     
  65. Primary sequence dependence of conformation in oligomannose oligosaccharides.
    E.W. Wooten, R. Bazzo, C.J. Edge, S.E. Zamze, R.A. Dwek and T.W. Rademacher (1990) Eur. Biophys. J., 18, 139-148. [Full text]
     
  66. Glycolipid precursors for the membrane anchor of Trypanosoma brucei variant surface glycoproteins: I. Can structure of the phosphatidylinositol-specific phospholipase C sensitive and resistant glycolipids.
    S. Mayor, A.K. Menon, G.A.M. Cross, M.A.J. Ferguson, R.A. Dwek and T.W. Rademacher (1990) J. Biol. Chem., 265, 6164-6173. [Full text]
     
  67. Agalacostyl IgG, antibodies to heat shock proteins and acute rheumatic fever.
    G.M. Bahr, A.M. Yousof, H.A.M. Majeed, K. Behbehani, M. Lubani, R.B. Parekh, R.A. Dwek, T.W. Rademacher, D.B. Young, A. Mehlert, J. Steele and G.A.W. Rook (1990) Ann. Rheum. Dis., 49, 383-386. [Full text]
     
  68. Agalactosyl IgG in inflammatory bowel disease: Correlation with C-reactive protein.
    R. Dube, G.A.W. Rook, J. Steele, R. Brealey, R.A. Dwek, T.W. Rademacher and J. Lennard-Jones (1990) Gut, 31, 431-434. [Full text]
     
  69. Structure, biosynthesis and function of Glycosyl-phosphatidylinositols.
    J.R. Thomas, R.A. Dwek and T.W. Rademacher (1990) Biochemistry, 29, 5413-5422. [Full text]
     
  70. Two-domain structure of the native and reactive centre cleaved forms of C1 inhibitor of human complement by neutron scattering.
    S.J. Perkins, K.F. Smith, S. Amatayakul, D.A. Ashford, T.W. Rademacher, R.A. Dwek, P.J. Lachmann and R.A. Harrison (1990) J. Mol. Biol., 214, 751-763. [Full text]
     
  71. Analysis of glycosylation changes of IgG using lectins.
    N. Sumar, K.B. Bodman, T.W. Rademacher, R.A. Dwek, P.J. Williams, R.B. Parekh, C.J. Edge, G.A.W. Rook, D.A. Isenberg, F.C. Hay and I.M. Roitt (1990) J. Immunol. Meth., 131, 127-136. [Full text]
     
  72. Structures of the N-linked oligosaccharides of Gp63, the major surface glycoprotein, from Leishmania mexicana amazonensis.
    R.W. Olafson, J.E. Thomas, M.A.J. Ferguson, R.A. Dwek, M. Chaudhuri, K.P. Chang and T.W. Rademacher (1990) J. Biol. Chem., 265, 12240-12247. [Full text]
     
  73. Uncertainties in structural determinations of oligosaccharide conformation using measurements of nuclear Overhauser effects.
    E.W. Wooten, C.J. Edge, R. Bazzo, R.A. Dwek and T.W. Rademacher (1990) Carbohydr. Res., 203, 13-17. [Full text]
     
  74. Full simulation of ROESY, including the Hartmann-Hahn effects.
    R. Bazzo, C.J. Edge, M.R. Wormald, T.W. Rademacher and R.A. Dwek (1990) Chem. Phys. Lett., 174, 313-319. [Full text]
     
  75. The isolation by ligand-affinity chromatography of a novel form of a-L-fucosidase from almond.
    P. Scudder, D.C.A. Neville, T.D. Butters, G.W.J. Fleet, R.A. Dwek, T.W. Rademacher and G.S. Jacob (1990) J. Biol. Chem., 265, 16472-16477. [Full text]
     
  76. The significance of changes in IgG carbohydrate in rheumatoid arthritis and tuberculosis.
    I.M. Roitt, R.A. Dwek, R.B. Parekh, T.W. Rademacher, C. Warren, A. Alavi, J.S. Axford, K.B. Bodman, A. Bond, B. Colaco, A. Cooke, P. Delves, F.C. Hay, D.A. Isenberg, P.M. Lydyard, L. Mackenzie, G. Rook, M. Smith, N. Sumar and G. Tsoulfa (1990) in "Molecular Aspects of Immune Response and Infectious Diseases", ed. H. Kiyona, E. Jirillo and C. DeSimone (Raven Press, New York).

    1991 - Top-Bottom

  77. The role of oil and agalactosyl IgG in the induction of arthritis in rodent models.
    G. Rook, S. Thompson, M. Buckley, C. Elson, R. Brealey, C. Lambert, T. Whyte and T.W. Rademacher (1991) Eur. J. Immunol., 21, 1027-1032. [Full text]
     
  78. The conformational effects of N-glycosylation on the tailpiece from serum IgM.
    M.R. Wormald, E.W. Wooten, R. Bazzo, C.J. Edge, A. Feinstein, T.W. Rademacher and R.A. Dwek (1991) Eur. J. Biochem., 198, 131-139. [Full text]
     
  79. Dropping anchor with the Lipophosphoglycans.
    T.W. Rademacher, C.J. Edge and R.A. Dwek (1991) Current Biology, 1, 41-42. [Full text]
     
  80. Syncytiotrophoblast membrane glycoprotein components block lymphocyte proliferation by interfering with an early event in their activation.
    P.D. Arkwright and C.W.G. Redman (1991) in Cellular and Molecular Biology of the Materno-Fetal Relationship, 212, 227-235
     
  81. Cell surface oligosaccharides on Dictyostelium during development.
    S. Amatayakul-Chantler, M.A.J. Ferguson, R.A. Dwek, T.W. Rademacher, R.B. Parekh, I.E. Crandall and P.C. Newell (1991) J. Cell Science, 99, 485-495. [Full text]
     
  82. The glycosylation of glycoprotein lectins: Intra- and inter-genus variation in N-linked oligosaccharride expression.
    D.A. Ashford, R.A. Dwek, T.W. Rademacher, H. Lis and N. Sharon (1991) Carbohydr. Res., 213, 215-227. [Full text]
     
  83. Changes in IgG glycoform levels are associated with remission of arthritis during pregnancy.
    G.A.W. Rook, J. Steele, R. Brealey, A. Whyte, D.A. Isenberg, N. Sumar, J.L. Nelson, K.B. Bodman, A. Young, I.M. Roitt, P.J. Williams, I.G. Scragg, C.J. Edge, P.D. Arkwright, D.A. Ashford, M.R. Wormald, P.M. Rudd, C.W.G. Redman, R.A. Dwek and T.W. Rademacher (1991) J. Autoimmunity, 4, 779-794. [Full text]
     
  84. Abnormalities in the glycosylation of IgG in spouses of patients with rheumatoid arthritis. A family study.
    N. Sumar, C.B. Colaço, K.B. Bodman, R.B. Parekh, P.J. Williams, R.A. Dwek, T.W. Rademacher, D.A. Isenberg, A. Soltys, F.C. Hay and I.M. Roitt (1991) J. Autoimmunity, 4, 907-914. [Full text]
     
  85. Glycobiology: a Coming of Age.
    P.M. Rudd and R.A. Dwek (1991) Chemistry & Industry, 18, 660-663.
     
  86. Structural characterization of the asparagine-linked oligosaccharides from Trypanosoma brucei type II and type III variant surface glycoproteins.
    S.E. Zamze, D.A. Ashford, E.W. Wooten, T.W. Rademacher and R.A. Dwek (1991) J. Biol. Chem., 266, 20244-20261. [Full text]
     
  87. Characterisation of oligosaccharides from Drosophila melanogaster glycoproteins.
    P.J. Williams, M.R. Wormald, R.A. Dwek, T.W. Rademacher, G.F. Parker and D.R. Roberts (1991) Biochim. Biophys. Acta, 1075, 146-153. [Full text]
     
  88. Detection of the lipid-linked precursor oligosaccharide of N-linked protein glycosylation in Drosophila Melanogaster.
    G.F. Parker, P.J. Williams, T.D. Butters and D.R. Roberts (1991) FEBS Letters, 290, 58-60. [Full text]
     
  89. Diversification of the IgG molecule by oligosaccharides.
    P.M. Rudd, R.J. Leatherbarrow, T.W. Rademacher and R.A. Dwek (1991) Mol. Immunol., 28, 1369-1378. [Full text]
     
  90. Purification to homogeneity of Charonia Lampas a-fucosidase by using sequential ligand-affinity chromatography.
    T.D. Butters, P. Scudder, J. Rotsaert, S. Petursson, G.W.J. Fleet, F.W. Willenbrock and G.S. Jacob (1991) Biochem. J., 279, 189-195. [Full text]
     
  91. The solution conformation of the Lex group.
    M.R. Wormald, C.J. Edge and R.A. Dwek (1991) Biochem. Biophys. Res. Commun., 180, 1214-1221. [Full text]
     
  92. Glycosylation in parasitic protozoa of the Trypanosomatidae family.
    S. Zamze (1991) Glycoconj. J., 8, 443-447. [Full text]
     
  93. Analysis and isolation of human transferrin receptor using OKT-9 monoclonal antibody covalently crosslinked to magnetic beads.
    G.B. Karlsson and F.M. Platt (1991) Analytical Biochemistry, 199, 219-222. [Full text]
     
  94. Syncytiotrophoblast membrane protein glycosylation patterns in normal human pregnancy and changes with gestational age and parturition.
    P.D. Arkwright, C.W.G. Redman, P.J. Williams, R.A. Dwek and T.W. Rademacher (1991) Placenta, 12, 637-651. [Full text]
     
  95. Advances in Glycobiology. Introduction.
    R.A. Dwek and R.B. Parekh (1991) Semin. Cell Biology, 2, 271-272.
  96. Network theory of glycosylation - etiologic and pathogenic implications of changes in IgG glycoform levels in autoimmunity.
    T.W. Rademacher (1991) Semin. Cell Biology, 2, 327-337.
     

    1992 - Top-Bottom

  97. Glycoprotein glycosylation and the immuno-suppressive effects of human pregnancy serum.
    P.D. Arkwright, T.W. Rademacher, J. Marshall, R.A. Dwek and C. Redman (1992) J. Reproductive Immunology, 21, 97-102. [Full text]
     
  98. Glycosylation of interleukin-6 purified from human blood mononuclear cells.
    R.B. Parekh, R.A. Dwek, T.W. Rademacher, G. Opdenakker and J. van Damme (1992) Eur. J. Biochem., 203, 135-141. [Full text]
     
  99. Detection of Multisulphated N-Linked Glycans in the L2/HNK-1 Carbohydrate Epitope Expressing Neural Adhesion Molecule Po.
    M.C. Field, D.R. Wing, R.A. Dwek, T.W. Rademacher, B. Schmitz, E. Bollensen and M. Schachner (1992) J. Neurochem., 58, 993-1000. [Full text]
     
  100. The role of mass spectrometry in glycobiology.
    D.J. Harvey (1992) Glycoconj. J., 9, 1-12. [Full text]
     
  101. New Methods for Measurement of Long-Range Proton-Carbon Coupling Constants in Oligosaccharides.
    D. Uhrin, A. Mele, J. Boyd, M.R. Wormald and R.A. Dwek (1992) J. Magn. Reson., 97, 411-418. [Full text]
     
  102. The Separation and Analysis of the Glycoform Populations of Ribonuclease B using Capillary Electrophoresis.
    P.M. Rudd, E. Coghill and R.A. Dwek (1992) Glycoconj. J., 9, 86-91. [Full text]
     
  103. Glycobiology.
    T.W. Rademacher and R.A. Dwek (1992) in "Fundamentals of Medical Cell Biology, 3A. Chemistry of the Living Cell", pp. 257-312 (JAI Press Inc.).
     
  104. Comparative Glycosylation in Neural Adhesion Molecules.
    D.R. Wing, T.W. Rademacher, B. Schmitz, M. Schachner and R.A. Dwek (1992) Biochem. Soc. Trans., 20, 386-390. [Full text]
     
  105. Carbohydrate analysis.
    D.A. Ashford (1992) Curr. Op. Biotech., 3, 45-48. [Full text]
     
  106. Fast Sequencing of Oligosaccharides: The Reagent Array Analysis Method.
    C.J. Edge, T.W. Rademacher, M.R. Wormald, R.B. Parekh, T.D. Butters, D.R. Wing and R.A. Dwek (1992) Proc. Natl. Acad. Sci. USA, 89, 6338-6342. [Full text]
     
  107. Therapeutic Challenges. Does Glycobiology Have a Role?
    T.W. Rademacher (1992) Trends in Biotechnology, 10, 227-230. [Full text]
     
  108. Effects of glycosylation on protein conformation and amide proton exchange rates in RNase B.
    H.C. Joao, I.G. Scragg and R.A. Dwek (1992) FEBS Letters, 307, 343-346. [Full text]
     
  109. Fast sequencing of oligosaccharides using arrays of enzymes.
    C.J. Edge, R.B. Parekh, T.W. Rademacher, M.R. Wormald and R.A. Dwek (1992) Nature, 358, 693-694. [Full text]
     
  110. Modulation of cell-surface transferrin receptor by the imino sugar N-butyldeoxynojirimycin.
    F.M. Platt, G.B. Karlsson and G.S. Jacob (1992) Eur. J. Biochem., 208, 187-193. [Full text]
     
  111. Synthesis of 1-N-Glycyl-b-Oligosaccharide Derivatives: Reactivity of Lens Culinaris Lectin with a Fluorescent Labeled Streptavidin Pseudoglycoprotein and Immobilized Neoglycolipid.
    I.D. Manger, T.W. Rademacher and R.A. Dwek (1992) Biochemistry, 31, 10733-10740. [Full text]
     
  112. 1-N-glycyl-b-Oligosaccharide Derivatives as Stable Intermediates for the Formation of Glycoconjugate Probes.
    I.D. Manger, T.W. Rademacher and R.A. Dwek (1992) Biochemistry, 31, 10724-10732. [Full text] [Correction]
     
  113. The use of large-scale hydrazinolysis in the preparation of N-linked oligosaccharide libraries: application to brain tissue.
    D.R. Wing, M.C. Field, B. Schmitz, G. Thor, R.A. Dwek, M.S. Schachner and T.W. Rademacher (1992) Glycoconj. J., 9, 293-301. [Full text]
     
  114. CDNA Amino Acid and Carbohydrate Sequence of Barley Seed Specific Peroxidase BP1. A Low Activity Peroxidase of Extensive Post Transitional Processing.
    A. Johansson, S.K. Rasmussen , J.E. Harthill and K.G. Welinder (1992) Plant Molecular Biology, 18, 1151-1161. [Full text]
     
  115. Aminosugar attenuation of HIV infection.
    G.S. Jacob, P. Scudder, T.D. Butters, I. Jones and D.C. Tiemeier (1992) in "Natural Products as Antiviral Agents", pp. 137-152, ed. C.K.Chu and H.G. Cutler (Plenum Press, New York).

    1993 - Top-Bottom

  116. Pre-eclampsia is associated with an increase in trophoblast glycogen content and glycogen synthase activity, similar to that found in hydatidiform moles.
    P.D. Arkwright, T.W. Rademacher, R.A. Dwek and C.W.G. Redman (1993) J. Clin. Invest., 91, 2744-2753. [Full text]
     
  117. Recognition of complex carbohydrates by the macrophage mannose receptor.
    M.E. Taylor (1993) Biochem. Soc. Trans., 21, 468-473. [Full text]
     
  118. Effects on the imino-sugar N-butyldeoxynojirimycin on N-glycosylation of recombinant gp 120.
    G.B. Karlsson, T.D. Butters, R.A. Dwek and F.M. Platt (1993) J. Biol. Chem., 268, 570-576. [Full text]
     
  119. Quantitative aspects of the matrix-assisted laser desorption mass spectrometry of complex oligosaccharides.
    D.J. Harvey (1993) Rapid Commun. Mass Spectrom., 7, 614-619. [Full text]
     
  120. Site-specific glycosylation of recombinant rat and human soluble CD4 variants expressed in chinese hamster ovary cells.
    D.A. Ashford, C.D. Alafi, V.M. Gamble, D.J.G. MacKay , T.W. Rademacher, P.J. Williams, R.A. Dwek, A.N. Barclay, S.J. Davis, C. Somoza, H.A. Ward and A.F. Williams (1993) J. Biol. Chem., 268, 3260-3267. [Full text]
     
  121. PROTOCOL. Expression of soluble recombinant glycoproteins with predefined glycosylation: application to the crystallization of the T-cell glycoprotein CD2.
    S.J. Davis, M.J. Puklavec, D.A. Ashford, K. Harlos, E.Y. Jones, D.I. Stuart and A.F. Williams (1993) Protein Engineering, 6, 229-232. [Full text]
     
  122. Selective Inverse Correlation by Using Chemical-Shift-Selective Pulses.
    D. Uhrin, A. Mele and R.A. Dwek (1993) J. Magn. Reson. Series A, 101, 98-102. [Full text]
     
  123. The conformational effects of N-linked glycosylation.
    C.J. Edge, H.C. Joao, R.J. Woods and M.R. Wormald (1993) Biochem. Soc. Trans., 21, 452-455. [Full text]
     
  124. Applications of electrospray mass spectrometry to studies on the structural properties of ribonuclease A and ribonuclease B.
    P. Camilleri, N.J. Haskins, P.M. Rudd and M.R. Saunders (1993) Rapid Commun. Mass Spectrom., 7, 332-335. [Full text]
     
  125. Use of Hydrazine to Release Intact and Unreduced Form both N-and O-Linked Oligosaccharides from Glycoproteins.
    T. Patel, J. Bruce, A. Merry, C. Bigge, M.R. Wormald, A. Jaques and R.B. Parekh (1993) Biochemistry, 32, 679-693. [Full text]
     
  126. Molecular Characterization of Limulus polyphemus C-reactive Protein I. Sub-unit Composition.
    G.A. Tennent, P.J.G. Butler, T. Hutton, A.R. Woolfitt, D.J. Harvey, T.W. Rademacher and M.B. Pepys (1993) Eur. J. Biochem., 214, 91-97. [Full text]
     
  127. Molecular Characterization of Limulus polyphemus C-reactive Protein II. Asparagine-Linked Oligosaccharides.
    S. Amatayakul-Chantler, R.A. Dwek, G.A. Tennent, M.B. Pepys and T.W. Rademacher (1993) Eur. J. Biochem., 214, 99-110. [Full text]
     
  128. Synthetic Glycosylation of Peptides using Unprotected Disaccharide and Oligosaccharide Glycosylamines.
    S.Y.C. Wong, G.R. Guile, T.W. Rademacher and R.A. Dwek (1993) Glycoconj. J., 10, 227-234. [Full text]
     
  129. Analysis of Glycoprotein-Associated Oligosaccharides.
    R.A. Dwek, C.J. Edge, D.J. Harvey, M.R. Wormald and R.B. Parekh (1993) Ann. Rev. Biochem., 62, 65-100. [Full text]
     
  130. Comparative analysis of the N-glycans of rat, mouse and human Thy-1. Site-Specific Oligosaccharide Patterns of Neural Thy-1, a Member of the Immunoglobin Superfamily.
    T.W. Rademacher, R.B. Parekh, D.R. Wing, A.C. Willis, A.N. Barclay, R. Dalchau, J.W. Fabre, R.A. Dwek and A.F. Williams (1993) Glycobiology, 3, 339-348. [Full text]
     
  131. The systematic use of negative nuclear Overhauser constraints in the determination of oligosaccharide conformations: application to sialyl-Lewis X.
    M.R. Wormald and C.J. Edge (1993) Carbohydr. Res., 246, 337-344. [Full text]
     
  132. Abberant control of galactosyltransferase in peripheral B-lymphocytes and Epstein-Barr virus transformed B-lymphoblasts from rheumatoid arthritic patients.
    I.B.H. Wilson, F.M. Platt, D.A. Isenberg and T.W. Rademacher (1993) J. Rheumatology, 20, 1282-1287.
     
  133. Biology of Animal Lectins.
    K. Drickamer and M.E. Taylor (1993) Ann. Rev. Cell. Biol., 9, 237-264. [Full text]
     
  134. Glycosylation of CD-4 and Thy-1.
    R.A. Dwek, D.A. Ashford, C.J. Edge, R.B. Parekh, T.W. Rademacher, D.R. Wing, A.N. Barclay, S.J. Davis and A.F. Williams (1993) Phil. Trans. R. Soc. Lond. B, 342, 43-50. [Full text]
     
  135. Effects of Glycosylation on protein structure and dynamics in Ribonuclease B.
    H.C. Joao and R.A. Dwek (1993) Eur. J. Biochem., 218, 239-244. [Full text]
     
  136. Neural glycoproteins: do they provide specific clues for our understanding of glycan functions?
    D.R. Wing (1993) Glycoconj. J., 10, 189-194. [Full text]
     
  137. Concepts and Principles of Glycobiology.
    G. Opdenakker, P.M. Rudd, C.P. Ponting and R.A. Dwek (1993) FASEB J., 7, 1330-1337. [Full text]
     
  138. Analysis of carbohydrate protein interactions with synthetic N-linked neoglycoconjugate probes.
    S.Y.C. Wong, I.D. Manger, G.R. Guile, T.W. Rademacher and R.A. Dwek (1993) Biochem. J., 296, 817-825. [Full text]
     
  139. Expression of soluble recombinant glycoproteins with predefined glycosylation: application to the crystallization of the T-cell glycoprotein CD2.
    S.J. Davis, M.J. Puklavec, D.A. Ashford, K. Harlos, E.Y. Jones, D.I. Stuart and A.F. Williams (1993) Protein Engineering, 6, 229-232. [Full text]
     
  140. Synthesis of 1,5-Dideoxy-3-0 (a-D-mannopyranosyl)-1, 5-imino-D-mannitol and 1,5-Dideoxy-3-0 (a-D-glucopyranosyl)-1,5-imino-D-mannitol: Powerful Inhibitors of an endoMannosidase.
    H. Ardron, T.D. Butters, F.M. Platt, M.R. Wormald, R.A. Dwek, G.W.J. Fleet and G.S. Jacob (1993) Tetrahedron: Asymmetry, 4, 2011-2024. [Full text]
     
  141. Absence of the McLafferty rearrangement ions in the tandem mass spectra of carboxylic acid esters.
    D.J. Harvey (1993) Org. Mass Spectrom., 28, 287-288. [Full text]
     
  142. Glycoprotein specificity and diversity.
    D.R. Wing (1993) in "Glycobiology and the brain", pp. 97-121, ed. M. Nicolini and P.F. Zatta (Pergamon Press, Oxford).
     
  143. Carbohydrate-recognition proteins of macrophages and related cells.
    M.E. Taylor (1993) in "Blood Cell Biochemistry, volume 5", ed. M.A. Horton (Springer).

    1994 - Top-Bottom

  144. 9-Fluorenymethoxycarbonyl (Fmoc)-glycine coupling of b -glycosylamines for the fractionation of oligosaccharides and the formation of N-linked neoglycoconjugates.
    G. Arsequell, R.A. Dwek and S.Y.C. Wong (1994) Anal. Biochem., 216, 165-170. [Full text]
     
  145. Glycoforms modify the dynamic stability and functional activity of an enzyme.
    P.M. Rudd, H.C. Joao, E. Coghill, P. Fiten, M.R. Saunders, G. Opdenakker and R.A. Dwek (1994) Biochemistry, 33, 17-22. [Full text]
     
  146. Suppression of allogeneic reactivity in vitro by the syncytiotrophoblast membrane glycocalyx of the human term placenta is carbohydrate dependent.
    P.D. Arkwright, T.W. Rademacher, F. Boutignon, R.A. Dwek and C.W.G. Redman (1994) Glycobiology, 4, 39-47. [Full text]
     
  147. N-butyldeoxynojirimycin is a novel inhibitor of glycolipid biosynthesis.
    F.M. Platt, G.R. Neises, R.A. Dwek and T.D. Butters (1994) J. Biol. Chem., 269, 8362-8365. [Full text]
     
  148. Structural Analysis of the N-Glycans from Human IgA1. Comparison of normal human serum immunoglobulin A1 with that isolated from patients with rheumatoid arthritis.
    M.C. Field, S. Amatayakul-Chantler, T.W. Rademacher, P.M. Rudd and R.A. Dwek (1994) Biochem. J., 299, 261-275. [Full text]
     
  149. GLYCAM 93: A Generalized Parameter Set for Molecular Dynamics Simulations of Glycoproteins and Oligosaccharides. Application to the Structure and Dynamics of a Disaccharide Related to Oligomannose.
    R.J. Woods, C.J. Edge, M.R. Wormald and R.A. Dwek (1994) in "Complex Carbohydrates in Drug Research", Alfred Benzon Symposium, 36, pp. 15-26, ed. K. Bock and H. Clausen (Munksgaard, Copenhagen). [Full text]
     
  150. Concluding remarks - Complex carbohydrates in drug research: Structural and functional aspects.
    R.A. Dwek and R.V. Lemieux (1994) in "Complex Carbohydrates in Drug Research", Alfred Benzon Symposium, 36, pp. 447-451, ed. K. Bock and H. Clausen (Munksgaard, Copenhagen).
     
  151. The secretion of human hepatitis B virus is inhibited by the imino-sugar, N-butyledeoxynojirimycin.
    T.M. Block, X. Lu, F.M. Platt, G.R. Foster, W.H. Gerlich, B.S. Blumberg and R.A. Dwek (1994) Proc. Natl. Acad. Sci. USA, 91, 2235-2239. [Full text]
     
  152. One-Dimensional Inverse-Detected Methods for Measurement of Long-Range Proton-Carbon Coupling Constants. Application to Saccharides.
    D. Uhrin, A. Mele, K.E. Kover, J. Boyd and R.A. Dwek (1994) J. Magn. Reson. Series A, 108, 160-170. [Full text]
     
  153. Human Serum amyloid P component is an invariant constituent of amyloid deposits and has a uniquely homogoneous glycostructure.
    M.B. Pepys, T.W. Rademacher, S.A. Chantler, P.J. Williams, G.E. Noble, W.L. Hutchinson, P.N. Hawkins, S.R. Nelson, J.R. Gallimore, J. Herbert, T. Hutton and R.A. Dwek (1994) Proc. Natl. Acad. Sci. USA, 91, 5602-5606. [Full text]
     
  154. Binding of Sugar Ligands to Ca2+-Dependent Animal Lectins: I. Analysis of mannose binding by site-directed mutagenesis and NMR.
    S.T. Iobst, M.R. Wormald, R.A. Dwek and K. Drickamer (1994) J. Biol. Chem., 269, 15505-15511. [Full text]
     
  155. Synthetic Glycosylation of Proteins using N-Haloacetamido b-Saccharide Derivatives: Applications in site-specific glycosylation and solid-phase enzymatic oligosaccharide synthesis.
    S.Y.C. Wong, G.R. Guile, G. Arsequell and R.A. Dwek (1994) Biochem. J., 300, 843-850. [Full text]
     
  156. Binding of Sugar Ligands to Ca2+-Dependent Animal Lectins: II. Generation of high affinity galactose binding by site-directed mutagenesis.
    S.T. Iobst and K. Drickamer (1994) J. Biol. Chem., 269, 15512-15519. [Full text]
     
  157. The agalactosyl glycoform of IgG autoantibodies are pathogenic.
    T.W. Rademacher, P.J. Williams and R.A. Dwek (1994) Proc. Natl. Acad. Sci. USA, 91, 6123-6127. [Full text]
     
  158. Recognition of carbohydrate by MHC class I restricted, glycopeptide specific cytotoxic T lymphocytes. Brief Definitive Report.
    J.S. Haurum, G. Arsequell, A.C. Lellouch, S.Y.C. Wong, R.A. Dwek, A.J. McMichael and T. Elliott (1994) J. Exp. Med., 180, 739-744. [Full text]
     
  159. Protein surface oligosaccharides and protein function.
    R.J. Woods, C.J. Edge and R.A. Dwek (1994) Nature Structural Biology, 1, 499-501. [Full text]
     
  160. A human T Cell receptor recognises "O"- linked sugars from the hinge region of human IgA1 and IgD.
    P.M. Rudd, F. Fortune, T.P. Patel, R.B. Parekh, R.A. Dwek and T. Lehner (1994) Immunol., 83, 99-106. [Full text]
     
  161. Matrix-assisted laser desorption/ionisation mass spectrometry of on a magnetic sector instrument fitted with an array detector.
    R.S. Bordoli, K. Howes, R.G. Vickers, R.H. Bateman and D.J. Harvey (1994) Rapid Commun. Mass Spectrom., 8, 585-589. [Full text]
     
  162. Analytical and preparative separation of anionic oligosaccharides by weak anion exchange high performance liquid chromatography on an inert polymer column.
    G.R. Guile, S.Y.C. Wong and R.A. Dwek (1994) Anal. Biochem., 222, 231-235. [Full text]
     
  163. Building Blocks for Solid-Phase Glycopeptide Synthesis: 2-Acetamido-2-deoxy-b-D-glycosides of FmocSerOH and FmocThrOH.
    G. Arsequell, L. Krippner, S.Y.C. Wong and R.A. Dwek (1994) J. Chem. Soc. Chem. Comm., issue 20, 2383-2384. [Full text]
     
  164. N-Butyldeoxygalactonojirimycin Inhibits Glycolipid Biosynthesis but does not affect N-linked Oligosaccharide Processing.
    F.M. Platt, G.R. Neises, G.B. Karlsson, R.A. Dwek and T.D. Butters (1994) J. Biol. Chem., 269, 27108-27114. [Full text]
     
  165. Purification of a cellular form on b-N-acetylglucosaminidase from Streptococcus pneumoniae.
    V.A. Clark, F.W. Willenbrock, P. Scudder, J. Rotsaert, G.S. Jacob and T.D. Butters (1994) IJBC, 1, 151-158.
     
  166. Early Agalactosylation of IgG is associated with a more progressive disease course in patients with Rheumatoid Arthritis: Results of a follow-up study.
    D. van Zeben, G.A.W. Rook, J.M.W. Hazes, A.H. Zwinderman, Y. Zhang, S. Ghelani, T.W. Rademacher and F.C. Breedveld (1994) British Journal of Rheumatology, 33, 36-43. [Full text]
     
  167. Tri- and Tetra-peptides incorporating an a-amino acid at the anomeric position of mannofuranose.
    J.C. Estevez, R.J. Estevez, H. Ardron, M.R. Wormald, D. Brown and G.W.J. Fleet (1994) Tetrahedron Letters, 35, 8885-8888. [Full text]
     
  168. Spirocyclic peptides at the anomeric position of mannofuranose.
    J.C. Estevez, H. Ardron, M.R. Wormald, D. Brown and G.W.J. Fleet (1994) Tetrahedron Letters, 35, 8889-8890. [Full text]
     
  169. Casuarine: A very highly oxygenated pyrrolizidine alkaloid.
    R.J. Nash, P.I. Thomas, R.D. Waigh, G.W.J. Fleet, M.R. Wormald, P.M. de Q. Lilley and D.J. Watkin (1994) Tetrahedron Letters, 35, 7849-7852. [Full text]
     
  170. Core fucosylation in honeybee venom.
    D.R. Wing (1994) Glycobiology, 4, 548-549. [Full text]
     
  171. Characterization of Ligand Binding to a Carbohydrate-Recognition Domain of the Macrophage Mannose Receptor.
    N.P. Mullin, K.T. Hall and M.E. Taylor (1994) J. Biol. Chem., 269, 28405-28413. [Full text]
     
  172. Synthesis of oxygen-substituted N-alkyl 1-deoxynojirimycin derivatives: as a sugar a-glucosidase inhibitors showing antiviral (HIV-1) and immunosuppressive activity.
    L.A.G.M. van den Broek, D.J. Vermas, F.J. van Kemenade, M.C.C.A. Tan, F.T.M. Rotteveel, P. Zandberg, T.D. Butters, F. Miedema, H.L. Ploegh and C.A.A. van Boeckel (1994) Recueil des Travaux Vhimiques des Pays-Bas, 113, 507-516.
     
  173. Crystal Structure of the Mutant D52S Hen Egg White Lysozyme with an Oligosaccharide Product.
    A.T. Hadfield, D.J. Harvey, D.B. Archer, D.A. MacKenzie, D.J. Jeenes, S.E. Radford, G. Lowe, C.M. Dobson and L.N. Johnson (1994) J. Mol. Biol., 243, 856-872. [Full text]
     
  174. Examination of complex oligosaccharides by matrix-assisted laser desorption mass spectrometry on time-of-flight and magnetic sector instruments.
    D.J. Harvey, P.M. Rudd, R.H. Bateman, R.S. Bordoli, K. Howes, J.B. Hayes and R.G. Vickers (1994) Organic Mass Spectrometry, 29, 753-765. [Full text]
     
  175. The Role of Nonbonded Interactions in Determining the Solution Conformations of Oligosaccharides.
    R.J. Woods, B. Fraser-Reid, R.A. Dwek and C.J. Edge (1994) ACS Symp. Series, 569, 252-268.
     
  176. Matrix-assisted laser desorption/ionisation mass spectrometry of oligosaccharides.
    D.J. Harvey (1994) American Laboratory, 26, 22-28.
     
  177. Galactosylation of human IgG monoclonal anti-D produced by EBV-transformed B-lymphoblastoid cell lines is dependent on culture method and affects Fc receptor-mediated functional activity.
    B.M. Kumpell, T.W. Rademacher, G.A.W. Rook, P.J. Williams and I.B.H. Wilson (1994) Hum. Antibod. Hybridomas, 5, 143-152.
     
  178. The Potential of Trees as Sources of New Drugs and Pesticide.
    R.J. Nash, A.C. Longland and M.R. Wormald (1994) in "Agroforestry Systems for Degraded Lands, Vol 2", pp. 899-910, ed. P. Singh, P.S. Pathak and M.M. Roy (Oxford & IBH, New Delhi). [Full text]

    1995 - Top-Bottom

  179. Ligand Binding by the Immunoglobulin Superfamily recognition molecule CD2 Is glycosylation independent.
    S.J. Davis, E.A. Davies, A.N. Barclay, S. Daenke, D.L. Bodian, E.Y. Jones, D.I. Stuart, T.D. Butters, R.A. Dwek and A. van der Merwe (1995) J. Biol. Chem., 270, 369-375. [Full text]
     
  180. The Activation of Plasminogen Glycoforms by Type I, Type II and Type II Dimer of Human Tissue Plasminogen Activator.
    K. Mori, R.A. Dwek, A.K. Downing, G. Opdenakker and P.M. Rudd (1995) J. Biol. Chem., 270, 3261-3267. [Full text]
     
  181. Glycobiology: Towards Understanding the Function of Sugars.
    R.A. Dwek (1995) Biochem. Soc. Trans., 23, 1-25. [Full text]
     
  182. Glycosylation changes of IgG associated with rheumatoid arthritis can activate complement via the mannose-binding protein.
    R. Malhotra, M.R. Wormald, P.M. Rudd, P.B. Fischer, R.A. Dwek and R.B. Sim (1995) Nature Medicine, 1, 237-243. [Full text]
     
  183. Potent Inhibition of Glycogen Phosphorylase by a Spirohydantoin of Glucopyranose: First Pyranose Analogues of Hydantocidin.
    C.J.F. Bichard, E.P. Mitchell, M.R. Wormald, K.A. Watson, L.N. Johnson, S.E. Zographos, D.D. Koutra, N.G. Oikonomakos and G.W.J. Fleet (1995) Tetrahedron Letters, 36, 2145-2148. [Full text]
     
  184. Cloning and expression of the b-N-acetylglucosaminidase gene from Streptococcus pneumonia: generation of truncated enzymes with modified aglycon specificity.
    V.A. Clarke, N. Platt and T.D. Butters (1995) J. Biol. Chem., 270, 8805-8814. [Full text]
     
  185. The effects of variable glycosylation on the functional activities of ribonuclease, plasminogen and tissue plasminogen activator.
    P.M. Rudd, R.J. Woods, M.R. Wormald, G. Opdenakker, A.K. Downing, I.D. Campbell and R.A. Dwek (1995) Biochim. Biophys. Acta, 1248, 1-10. [Full text]
     
  186. Cells regulate the activities of cytokines by glycosylation.
    G. Opdenakker, P.M. Rudd, M.R. Wormald, R.A. Dwek and J. van Damme (1995) FASEB J., 9, 453-457. [Full text]
     
  187. Multiplicity of lectin - carbohydrate interactions.
    K. Drickamer (1995) Nature Structural Biology, 2, 437-439. [Full text]
     
  188. Lectin-carbohydrate interactions in disease. T-Cell recognition of IgA and IgD; mannose binding protein recognition of IgG0.
    P.M. Rudd, F. Fortune, T. Lehner, R.B. Parekh, T.P. Patel, M.R. Wormald, R. Malhotra, R. Sim and R.A. Dwek (1995) Adv. Exp. Med. Biol., 376, 147-151. [Full text]
     
  189. Synthesis of Major Histocompatibility Complex Class I Binding Glycopeptides.
    G. Arsequell, J.S. Haurum, T. Elliott, R.A. Dwek and A.C. Lellouch (1995) J. Chem. Soc. Perkin Trans I, 1739-1745. [Full text]
     
  190. Molecular Mechanical and Molecular Dynamical Simulations of Glycoproteins and Oligosaccharides. 1. GLYCAM-93 Parameter Development.
    R.J. Woods, R.A. Dwek, C.J. Edge and B. Fraser-Reid (1995) J. Phys. Chem., 99, 3832-3846. [Full text]
     
  191. The a-Glucosidase Inhibitor N-Butyldeoxynojirimycin Inhibits Human Immunodeficiency Virus Entry at the Post-CD4 Binding Level.
    P.B. Fischer, M. Collin, G.B. Karlsson, W. James, T.D. Butters, S.J. Davis, S. Gordon, R.A. Dwek and F.M. Platt (1995) J. Virology, 69, 5791-5797. [Full text]
     
  192. Determination of N-terminal myristoylation of proteins using a combined gas chromatographic/mass spectrometric assay of derived myristoyl glycine: Electron impact-induced fragmentation of acylglycine derivatives.
    R.A.J. McIlhinney and D.J. Harvey (1995) J. Mass Spectrom., 30, 900-910. [Full text]
     
  193. Matrix-assisted laser desorption/ionisation mass spectrometry of sphingo- and glycosphingo-lipids.
    D.J. Harvey (1995) J. Mass Spectrom., 30, 1311-1324. [Full text]
     
  194. Matrix-assisted laser desorption/ionization mass spectrometry of phospolipids.
    D.J. Harvey (1995) J. Mass Spectrom., 30, 1333-1346. [Full text]
     
  195. Glycobiology: More Functions for Oligosaccharides.
    R.A. Dwek (1995) Science, 269, 1234-1235. [Full text]
     
  196. Glycobiology: The Function of Sugar in the IgG Molecule.
    R.A. Dwek, A.C. Lellouch and M.R. Wormald (1995) J. Anat., 187, 279-292. [Full text]
     
  197. Spirodiketopiperazines at the anomeric position of mannopyranose: Novel N-Linked Glycopeptides incorporating an a-amino acid at the anomeric position of mannopyranose.
    J.C. Estevez, D.D. Long, M.R. Wormald, R.A. Dwek and G.W.J. Fleet (1995) Tetrahedron Letters, 36, 8287-8290. [Full text]
     
  198. Gas chromatography - mass spectrometry.
    D.J. Harvey (1995) in "Encyclopedia of Analytical Science", pp. 1811-1819 (Academic Press, London).
     
  199. Inhibitors of Glycosphingolipid Biosynthesis.
    F.M. Platt and T.D. Butters (1995) Trends in Glycoscience and Glycotechnology, 7, 495-511. [Full text]
     
  200. Comparison of fragmentation modes for the structural determination of complex oligosaccharides ionized by matrix-assisted laster desorption/ionization mass spectrometry.
    D.J. Harvey, T.J.P. Naven and B. Kuster (1995) Rapid Commun. Mass Spectrom., 9,1556-1561. [Full text]
     
  201. Peptide anchor residue glycosylation: effect on class I major histocompatibility complex binding and cytotoxic T lymphocyte recognition.
    J.S. Haurum, L. Tan, G. Arsequell, A.C. Lellouch, P.A.H. Moss, R.A. Dwek, A.J. McMichael and T. Elliott (1995) Eur. J. Immunol, 25, 3270-3276. [Full text]
     
  202. Evidence that N-linked glycosylation is necessary for hepatitis B virus secretion.
    X. Lu, A. Mehta, R.A. Dwek, T.D. Butters and T.M. Block (1995) Virology, 213, 660-665. [Full text]
     
  203. Selective placental transport of maternal IgG to the fetus.
    P.J. Williams, P.D. Arkwright, I.G. Scragg, C.J. Edge, M.R. Wormald, P.M. Rudd and T.W. Rademacher (1995) Placenta, 16, 749-756. [Full text]
     
  204. Editorial overview - Carbohydrates and glycoconjugates.
    K. Drickamer and R.A. Dwek (1995) Curr. Op. Struc. Biol., 5, 589-590. [Full text]
     
  205. Increasing diversity of animal lectin structures.
    K. Drickamer (1995) Curr. Op. Struc. Biol., 5, 612-616. [Full text]
     
  206. Glycoprotein analysis.
    T.D. Butters (1995) in “Molecular Biotechniques”, pp.491-502, ed. R. Rapley and J.M. Walker (Humana Press).

    1996 - Top-Bottom

  207. Synthesis of a-glucosidase I inhibitors showing antiviral (HIV-1) and immunosuppressive activity.
    L.A.G.M. van den Broek, M.W.P. Kat-Van Den Nieuwenhof, T.D. Butters and C.A.A. van Boeckel (1996) J. Pharm. Pharmacol., 48, 172-178.
     
  208. A galactopyranose analogue of hydantocidin.
    T.W. Brandstetter, M.R. Wormald, R.A. Dwek, T.D. Butters, F.M. Platt, K.E. Tsitsanou, S.E. Zographos, N.G. Oikonomakos and G.W.J. Fleet (1996) Tetrahedron: Asymmetry, 7, 157-170. [Full text]
     
  209. Effect of Serine O-Glycosylation on Cis-Trans Proline Isomerization.
    Y.L. Pao, M.R. Wormald, R.A. Dwek and A.C. Lellouch (1996) Biochem. Biophys. Res. Commun., 219, 157-162. [Full text]
     
  210. Site-specific glycosylation changes of human Immunoglobulin G in altered in four rheumatoid arthritis patients.
    A. Youings, S.C. Chang, R.A. Dwek and I.G. Scragg (1996) Biochem. J., 314, 621-630. [Full text]
     
  211. Glycobiology: Towards understanding the function of sugars.
    R.A. Dwek (1996) Chemical Reviews, 96, 683-720. [Full text]
     
  212. Matrix-assisted laser desorption/ionisation mass spectrometry of oligosaccharides and glycoconjugates.
    D.J. Harvey (1996) J. Chromatogr. A, 720, 429-446. [Full text]
     
  213. Mimics of L-Rhamnose: Analogues of rhamnopyranose containing a constituent a-amino acid at the anomeric position. A pyranose analogue of hydantocidin.
    J.C. Estevez, M.D. Smith, M.R. Wormald, G.S. Besra, P.J. Brennan and G.W.J. Fleet (1996) Tetrahedron: Asymmetry, 7, 391-394. [Full text]
     
  214. Cationic derivitization of oligosaccharides with Girard's T reagent for improved prerfomance in matrix-assisted laser desorption/ionization and electrospray mass spectrometry.
    T.J.P. Naven and D.J. Harvey (1996) Rapid Commun. Mass Spectrom., 10, 829-834. [Full text]
     
  215. The glycosylation of Bowes melanoma tissue plasminogen activator: lectin mapping, reaction with anti-L2/HNK-1 antibodies and the presence of sulphated/glucuronic acied containing glycans.
    A.J. Jacques, G. Opdenakker, T.W. Rademacher, R.A. Dwek and S.E. Zamze (1996) Biochem. J., 316, 427-437. [Full text]
     
  216. Effect of structure on the signal strength of oligosaccharides in matrix-assisted laser desorption/ionization mass spectrometry on time-of-flight and magnetic sector instruments.
    T.J.P. Naven and D.J. Harvey (1996) Rapid Commun. Mass Spectrom., 10, 1361-1366. [Full text]
     
  217. Megalin-mediated endocytosis of transcobalamin-vitamin-B12 complexes suggests a role of the receptor in vitamin-B12 homeostasis.
    S.K. Moestrup, H. Birns, P.B. Fischer, C.M. Petersen, P.J. Verroust, R.B. Sim, E.I. Christensen and E. Nexo (1996) Proc. Natl. Acad. Sci. USA, 93, 8612-8617. [Full text]
     
  218. The use of electrospray ionization MS to determine the structure of glycans in intact glycoproteins.
    R.W.A. Oliver, B.N. Green and D.J. Harvey (1996) Biochem. Soc. Trans., 24, 917-927. [Full text]
     
  219. Affinity and kinetic analysis of the bovine plasma C-type lectin collectin-43 (CL-43) interacting with mannan.
    U. Holmskov, P.B. Fischer, A. Rothmann and P. Hojrup (1996) FEBS Letters, 393, 314-316. [Full text]
     
  220. A rapid high resolution HPLC method for separating oligosaccharide mixtures and analysing sugar prints.
    G.R. Guile, P.M. Rudd, D.R. Wing, S.B. Prime and R.A. Dwek (1996) Anal. Biochem., 240, 210-226. [Full text]
     
  221. Identification of oligosacchrides by matrix-assisted laser desorption and electrospray mass spectrometry.
    D.J. Harvey, T.J.P. Naven and B. Kuster (1996) Biochem. Soc. Trans., 24, 905-912. [Full text]
     
  222. Identification of cleaved oligosaccharides by matrix-assisted laser desorption/ionization.
    D.J. Harvey (1996) in "Methods in Molecular Biology, Vol. 61", pp.243-253.
     
  223. N-Butyleoxynojirimycin mediated inhibition of HIV entry correlates with impairment of gp120 shedding and gp41 exposure.
    P.B. Fischer, G.B. Karlsson, R.A. Dwek and F.M. Platt (1996) J. Virology, 70, 7153-7160. [Full text]
     
  224. N-Butyldeoxynojirimycin-mediated inhibition of human immunodeficiency virus entry correlates with changes in antibody recognition of the V1/V2 region of gp120.
    P.B. Fischer, G.B. Karlsson, T.D. Butters, R.A. Dwek and F.M. Platt (1996) J. Virology, 70, 7143-7152. [Full text]
     
  225. Rapid approach for sequencing neutral oligosaccharides by exoglycosidase digestion and matrix-assisted laser desorption ionisation/time of flight Mass Spectrometry.
    B. Kuster, T.J.P. Naven and D.J. Harvey (1996) J. Mass Spectrom., 31, 1131-1140. [Full text]
     
  226. Stabilization of sialic acids in N-linked oligosaccharides and gangliosides for analysis by positive ion matrix-assisted laser desorption/ionization mass spectrometry.
    A.K. Powell and D.J. Harvey (1996) Rapid Commun. Mass Spectrom., 10, 1027-1032. [Full text]
     
  227. Effect of the reducing-terminal substituents on the high energy chemically induced decay/matrix-assisted laser desorption ionisation mass spectra of oligosaccharides.
    B. Kuster, T.J.P. Naven and D.J. Harvey (1996) Rapid Commun. Mass Spectrom., 10, 1645-1651. [Full text]
     
  228. Unusual uniformity of the N-linked oligosaccharides of HLA-A, -B and -C glycoproteins.
    L.D. Barber, T.P. Patel, L. Percival, J.E. Gumperz, L.L. Lanier, J.H. Phillips, C. Bigge, M.R. Wormald, R.B. Parekh and P. Parham (1996) J. Immunol., 156, 3275-3284. [Full text]
     
  229. The isolation from nicandra physalodes and identification of the 3-O-b-D-glucopyranoside of 1a,2b,3a,6a-tetrahydroxy-nor-tropane (Calystegine B1).
    R.C. Griffiths, A.A. Watson, K. Haruhisa, N. Asano, H.J. Sharp, M.G. Jones, M.R. Wormald, G.W.J. Fleet and R.J. Nash (1996) Tetrahedron Letters, 37, 3207-3208. [Full text]
     
  230. Structural analysis of monosaccharide recognition by rat liver mannose-binding protein.
    K.K.S. Ng, K. Drickamer and W.I. Weis (1996) J. Biol. Chem., 271, 663-674. [Full text]
     
  231. Selective sugar binding to the carbohydrate-recognition domain of rat hepatic and macrophage asialoglycoprotein receptors.
    S.T. Iobst and K. Drickamer (1996) J. Biol. Chem., 271, 6686-6693. [Full text]
     
  232. Introduction of selectin-like binding specificity into a homologous mannose-binding protein.
    O. Blanck, S.T. Iobst, C. Gabel and K. Drickamer (1996) J. Biol. Chem., 271, 7289-7292. [Full text]
     
  233. Differential ligand binding to two subunits of the rat liver asialoglycoprotein receptor.
    N.I. Ruiz and K. Drickamer (1996) Glycobiology, 6, 551-559. [Full text]
     
  234. Structural basis of lectin-carbohydrate recognition.
    W.I. Weis and K. Drickamer (1996) Ann. Rev. Biochem., 65, 441-473. [Full text]
     
  235. Ca2+-Dependent sugar recognition by animal lectins.
    K. Drickamer (1996) Biochem. Soc. Trans., 24, 146-150. [Full text]
     
  236. Breaking the curse of the AGEs.
    K. Drickamer (1996) Nature, 382, 211-212. [Full text]
     
  237. The identification of abnormal glycoforms of serum transferrin in carbohydrate deficient glycoprotein syndrome by capillary electrophoresis.
    O. Iourin, T.S. Mattu, G. Kier, B. Winchester, P.M. Rudd and R.A. Dwek (1996) Glycoconj. J., 13, 1031-1042. [Full text]
     
  238. Casuarine-6-a-D-glucoside from Casuarina equisetifolia and Eugenia jamolana.
    M.R. Wormald, R.J. Nash, A.A. Watson, B.B.K. Bhadoria, R. Langford, M. Sims and G.W.J. Fleet (1996) Carbohydrate Lett., 2, 169-174. [Full text]
     
  239. Oligosaccaride Release from Frozen and Paraffin-Wax-Embedded Archival Tissues.
    M.V. Dwek, S.A. Brooks, A.J. Streets, D.J. Harvey and A.J.C. Leathem (1996) Anal. Biochem., 242, 8-14. [Full text]
     
  240. Glycobiology, a quatum leap in carbohydrate chemistry.
    R.A. Dwek (1996) Quantum Leaps in Biochem., 2, 153-202.
     
  241. Matrix-assisted laser desorption mass spectrometry of on a magnetic sector instrument fitted with an array detector.
    R.S. Bordoli, K. Howes, R.G. Vickers, R.H. Bateman and D.J. Harvey (1996) NATO ASI Series C, 475, 51-60.
     
  242. From antibodies to glycobiology.
    R.A. Dwek (1996) in "Encyclopedia of Nuclear Magnetic Resonance. Volume 1", pp. 1-2, ed. D.M. Grant and R.K. Harris (John Wiley & Sons, Chichester).
     
  243. Haptens and antibodies.
    R.A. Dwek (1996) in "Encyclopedia of Nuclear Magnetic Resonance. Volume 4", pp. 2243-2249, ed. D.M. Grant and R.K. Harris (John Wiley & Sons, Chichester).

    1997 - Top-Bottom

  244. Conformation independent binding of monoglucosylated ribonuclease B to calnexin.
    A. Zapun, S.M. Petrescu, P.M. Rudd, R.A. Dwek, D.Y. Thomas and J.J.M. Bergeron (1997) Cell, 88, 29-38. [Full text]
     
  245. Variations in oligosaccharide-protein interactions in immunoglobulin G determine the site-specific glycosylation profiles and modulate the dynamic motion of the Fc oligosaccharides.
    M.R. Wormald, P.M. Rudd, D.J. Harvey, S.C. Chang, I.G. Scragg and R.A. Dwek (1997) Biochemistry, 36, 1370-1380. [Full text]
     
  246. High-energy collision-induced fragmentation of complex oligosaccharides ionized by matrix-assisted laser desorption/ionization mass spectrometry.
    D.J. Harvey, R.H. Bateman and M.R. Green (1997) J. Mass Spectrom., 32, 167-187. [Full text]
     
  247. The glycosylation of the influenza A virus haemagglutinin by mammalian cells - a site specific study.
    S.Y. Mir-Shekari, D.A. Ashford, D.J. Harvey, R.A. Dwek and I.T. Schulze (1997) J. Biol. Chem., 272, 4027-4036. [Full text]
     
  248. Glycosylation: Heterogeneity and the 3D Structure of Proteins.
    P.M. Rudd and R.A. Dwek (1997) Crit. Rev. Biochem. Mol. Biol., 32, 1-100. [Full text]
     
  249. Mechanism of Ca2+ and monosaccharide-binding to a c-type carbohydrate recognition domain of the macrophage mannose receptor.
    M.E. Taylor, P.G. Hitchen and N.P. Mullin (1997) J. Biol. Chem., 272, 5668-5681. [Full text]
     
  250. Hepatitis B virus (HBV) envelope glycoproteins vary drastically in their sensitivity to glycan processing: Evidence that a single N-linked glycosylation site on an HBV envelope protein is crucial for virus secretion - a potential therapeutic target.
    A. Mehta, X. Lu, T.M. Block, B.S. Blumberg and R.A. Dwek (1997) Proc. Natl. Acad. Sci. USA, 94, 1822-1827. [Full text]
     
  251. The glycosylation of the complement regulatory protein, human erythrocytes CD59.
    P.M. Rudd, B.P. Morgan, M.R. Wormald, D.J. Harvey, C.W. van den Berg, S.J. Davis, M.A.J. Ferguson and R.A. Dwek (1997) J. Biol. Chem., 272, 7229-7244. [Full text]
     
  252. Abberrant trafficking of hepatitis B virus glycoproteins in cells in which N-glycan processing is inhibited.
    X. Lu, A. Mehta, M. Dadmarz, R.A. Dwek, B.S. Blumberg and T.M. Block (1997) Proc. Natl. Acad. Sci. USA, 94, 2380-2385. [Full text]
     
  253. Prevention of lysosomal storage in Tay-Sachs mice treated with N-butyldeoxynojirmycin.
    F.M. Platt, G.R. Neises, G. Reinkensmeier, M.J. Townsend, V.H. Perry, R.L. Proia, B. Winchester, R.A. Dwek and T.D. Butters (1997) Science, 276, 428-431. [Full text]
     
  254. Letter to GlycoForum - Evolution of a family of receptors containing multiple c-type carbohydrate recognition domains.
    M.E. Taylor (1997) Glycobiology, 7, v-viii. [Full text]
     
  255. Structural determination of protein-bound oligosaccharides by mass spectrometry.
    D.J. Harvey (1997) in "Glycopeptides and related compounds: synthesis, analysis and applications", pp. 593-629, ed. E.G. Large and C.D. Warren (Marcel-Dekker, New York).
     
  256. Novel biologically active alkaloids from British plants.
    R.J. Nash, A.A. Watson, A.L. Winters, G.W.J. Fleet, M.R. Wormald, S. Dealler, E. Lees, N. Asano and H. Kizu (1997) in "Phytochemical Diversity", pp. 106-114, ed. S. Wrigley, M. Hayes, R. Thomas and E. Chrystal (The Royal Society of Chemistry). [Full text]
     
  257. Letter to GlycoForum - Ammonium containing buffers should be avoided during enzymatic release of glycans from glycoproteins when followed by reducing terminal derivatisation.
    B. Kuster and D.J. Harvey (1997) Glycobiology, 7, vii-ix. [Full text]
     
  258. Sequencing of N-linked oligosaccharides directly from protein gels: In-gel deglycosylation followed by matrix-assisted laser desorption/ionisation mass spectrometry and normal-phase high performance liquid chromatography.
    B. Kuster, S.F. Wheeler, A.P. Hunter, R.A. Dwek and D.J. Harvey (1997) Anal. Biochem., 250, 82-101. [Full text]
     
  259. The solution NMR structure of glucosylated N-glycans involved in the early stages of glycoprotein biosynthesis and folding.
    A.J. Petrescu, T.D. Butters, G. Reinkensmeier, S.M. Petrescu, F.M. Platt, R.A. Dwek and M.R. Wormald (1997) EMBO J., 16, 4302-4310. [Full text]
     
  260. Oligosaccharide sequencing technology.
    P.M. Rudd, G.R. Guile, B. Kuster, D.J. Harvey, G. Opdenakker and R.A. Dwek (1997) Nature, 388, 205-208. [Full text]
     
  261. Inhibition of N-glycan processing in B16 Melanoma cells results in inactivation of tyrosinase but does not prevent its transport to the melanosome.
    S.M. Petrescu, A.J. Petrescu, H.N. Titu, R.A. Dwek and F.M. Platt (1997) J. Biol. Chem., 272, 15796-15803. [Full text]
     
  262. Rapid sensitive sequencing of oligosaccharides from glycoproteins.
    P.M. Rudd and R.A. Dwek (1997) Curr. Op. Biotech., 8, 488-497. [Full text]
     
  263. Extensive glycosphingolipid depletion in the liver and lymphoid organs of mice treated with N-butyldeoxynojirimycin.
    F.M. Platt, G. Reinkensmeier, R.A. Dwek and T.D. Butters (1997) J. Biol. Chem., 272, 19365-19372. [Full text]
     
  264. HPLC strategies for profiling and sequencing oligosaccharides.
    G.R. Guile, P.M. Rudd, D.R. Wing and R.A. Dwek (1997) in "A Laboratory Guide to Glycoconjugate Analysis", pp. 199-234, ed. P. Jackson and J.T. Gallagher (Birkhauser).
     
  265. Myristoylated and nonmyristoylated pools of sea urchin sperm flagellar creatine kinase exist side by side:  myristoylation is necessary for efficient lipid association.
    A.F.G. Quest, D.J. Harvey and R.A.J. McIlhinney (1997) Biochemistry, 36, 6993-7002. [Full text]
     
  266. Fragmentation of complex carbohydrates following ionization by matrix-assisted laser desorption with an instrument fitted with time-lag focusing.
    T.J.P. Naven and D.J. Harvey (1997) Rapid Commun. Mass Spectrom., 11, 1681-1686. [Full text]
     
  267. Ultrastructural changes in the Golgi apparatus and secretory granules of HL-60 cells treated with the inimo sugar N-butyldeoxynojirimycin.
    G.R. Neises, P.G. Woodman, T.D. Butters, R.L. Ornberg and F.M. Platt (1997) Biology of the Cell, 89, 123-131. [Full text]
     
  268. Selective binding of N-acetylglucosamine to the chicken hepatic lectin.
    L. Burrows, S.T. Iobst and K. Drickamer (1997) Biochem. J., 324, 673-680. [Full text]
     
  269. Asymmetry adjacent to the collagen-like domain in rat liver mannose-binding protein.
    R. Wallis and K. Drickamer (1997) Biochem. J., 325, 391-400. [Full text]
     
  270. Minireview - Making a fitting choice: common aspects of sugar-binding sites in plant and animal lectins.
    K. Drickamer (1997) Structure, 5, 465-468. [Full text]
     
  271. Glycosidase-inhibiting pyrrolidine alkaloids from Hyacinthoides non-scripta.
    A.A. Watson, R.J. Nash, M.R. Wormald, D.J. Harvey, S. Dealler, E. Lees, N. Asano, H. Kizu, A. Kato, R.C. Griffiths, A.J. Cairns and G.W.J. Fleet (1997) Phytochemistry, 46, 255-259. [Full text]
     
  272. Characterization of oligosaccharide composition and structure by quadrupole  ion trap mass spectrometry.
    A.S. Weiskopf, P. Vouros and D.J. Harvey (1997) Rapid Commun. Mass Spectrom., 11, 1493-1504. [Full text]
     
  273. A strategy for anti-viral intervention: the use of a-glucosidase inhibitors to  prevent chaperone mediated folding of viral envelope glycoproteins.
    A. Mehta, P.M. Rudd, T.M. Block and R.A. Dwek (1997) Biochem. Soc. Trans., 25, 1188-1194. [Full text]
     
  274. Roles for glycosylation in the anti-inflammatory molecule, CD59.
    P.M. Rudd, B.P. Morgan, M.R. Wormald, D.J. Harvey, C.W. van den Berg, S.J. Davis, M.A.J. Ferguson and R.A. Dwek (1997) Biochem. Soc. Trans., 25, 1177-1184. [Full text]
     
  275. N-linked oligosaccharide expression in whole tissue and specific glycoproteins of rodent CNS.
    D.R. Wing, Y.J. Chen, R.A.C. Clark, R.A. Dwek and S.E. Zamze (1997) in "Neurochemistry", pp. 929-932, ed.Teelken and Korf (Plenum Press, New York).
     
  276. Editorial overview - Carbohydrates and glycoconjugates.
    J. Rini and K. Drickamer (1997) Curr. Op. Struc. Biol., 7, 615-616. [Full text]

    1998 - Top-Bottom

  277. Neutral N-glycans in adult rat brain tissue: complete characterisation reveals fucosylated hybrid and complex structures.
    Y.J. Chen, D.R. Wing, G.R. Guile, R.A. Dwek, D.J. Harvey and S. Zamze (1998) Eur. J. Biochem., 251, 691-703. [Full text]
     
  278. The glycosylation and structure of human serum IgA1, Fab and Fc regions and the role of N-glycosylation on Fca receptor interactions.
    T.S. Mattu, R.J. Pleass, A.C. Willis, M. Killian, M.R. Wormald, A.C. Lellouch, P.M. Rudd, J.M. Woof and R.A. Dwek (1998) J. Biol. Chem., 273, 2260-2272. [Full text]
     
  279. Genomic cloning and expression of three murine UDP-galactose: b-N-acetylglucosamine b-1,3-galactosyltransferase genes.
    T. Hennet, A. Dinter, P. Kuhnert, T.S. Mattu, P.M. Rudd and E.G. Berger (1998) J. Biol. Chem., 273, 58-65. [Full text]
     
  280. Inhibition of glycosphingolipid biosynthesis does not impair growth or morphogenesis of the postimplantation mouse embryo.
    J.V. Brigande, F.M. Platt and T.N. Seyfried (1998) J. Neurochem., 70, 871-882. [Full text]
     
  281. The C-type lectin superfamily in the immune system.
    W.I. Weis, M.E. Taylor and K. Drickamer (1998) Immunol. Rev., 163, 19-34. [Full text]
     
  282. Structural characterization of the N-linked oligosaccharides derived from HIVgp120 expressed in lepidoteran cells.
    T.D. Butters, B. Yudkin, G.S. Jacob and I.M. Jones (1998) Glycoconj. J., 15, 83-88. [Full text]
     
  283. Novel sequential solid-phase synthesis of N-linked glycopeptides from natural sources.
    E. Meinjohanns, M. Meldal, H. Paulsen, R.A. Dwek and K. Bock (1998) J. Chem. Soc. Perkin Trans. I, 549-560. [Full text]
     
  284. Cytokine and protease glycosylation as a regulatory mechanism in inflammation and autoimmunity.
    P. Van den Steen, P.M. Rudd, R.A. Dwek, J. van Damme and G. Opdenakker (1998) Adv. Exp. Med. Biol., 435, 133-143.
     
  285. The glycosylation of the complement regulatory protein, human erythrocyte CD59.
    P.M. Rudd, B.P. Morgan, M.R. Wormald, D.J. Harvey, C.W. van den Berg, S.J. Davis, M.A.J. Ferguson and R.A. Dwek (1998) Adv. Exp. Med. Biol., 435, 153-162. [Full text]
     
  286. The role of N-linked glycosylation in the secretion of Hepatitis B Virus.
    A. Mehta, T.M. Block and R.A. Dwek (1998) Adv. Exp. Med. Biol., 435, 195-204.
     
  287. Role of glycan processing in Hepatitis B virus envelope protein trafficking.
    T.M. Block, X. Lu, A. Mehta, J. Park, B.S. Blumberg and R.A. Dwek (1998) Adv. Exp. Med. Biol., 435, 207-216.
     
  288. Mechanism of ligand binding to E- and P-selectin analysed using selectin/mannose-binding protein chimeras.
    D. Torgersen, N.P. Mullin and K. Drickamer (1998) J. Biol. Chem., 273, 6254-6261. [Full text]
     
  289. The importance of sugars for the function of antibodies.
    P.M. Rudd and R.A. Dwek (1998) Immunology News, 5, 84-89.
     
  290. Perspectives in the glycosciences - Matrix-assisted laser desorption/ionisation (MALDI) mass spectrometry of carbohydrates.
    D.J. Harvey, B. Kuster and T.J.P. Naven (1998) Glycoconj. J., 15, 333-338. [Full text]
     
  291. Mutant analysis reveals an alternative pathway for N-linked glycosylation in Drosophila melanogaster.
    D.B. Roberts, W.J. Mulvany, R.A. Dwek and P.M. Rudd (1998) Eur. J. Biochem., 253, 494-498. [Full text]
     
  292. Spirodiketopiperazines of mannofuranose: carbopeptoid a-amino acid esters at the anomeric position of mannofuranose.
    J.C. Estevez, J.W. Burton, R.J. Estevez, H. Ardron, M.R. Wormald, R.A. Dwek, D. Brown and G.W.J. Fleet (1998) Tetrahedron: Asymmetry, 9, 2137-2154. [Full text]
     
  293. Treatment of chronic hepadnavirus infection in a woodchuck animal model with an inhibitor of protein folding and trafficking.
    T.M. Block, X.Y. Lu, A.S. Mehta, B.S. Blumberg, B. Tennant, M. Ebling, B. Korba, D.M. Lansky, G.S. Jacob and R.A. Dwek (1998) Nature Medicine, 4, 610-614. [Full text]
     
  294. Identification of lectin-purified neural glycoproteins, GPs 180, 116 and 110, with NMDA and AMPA receptor subunits: conservation of glycosylation at the synapse.
    R.A.C. Clark, J.W. Gurd, N. Bissoon, N. Tricaud, E. Molnar, S.E. Zamze, R.A. Dwek, R.A.J. McIlhinney and D.R. Wing (1998) J. Neurochem., 70, 2594-2605. [Full text]
     
  295. Glycosidase inhibitors in British plants as causes of livestock disorders.
    R.J. Nash, A.A. Watson, A.L. Winters, G.W.J. Fleet, M.R. Wormald, S. Dealler, E. Lees, N. Asano and R.J. Molyneux (1998) in “Toxic plants and other natural toxicants”, pp.276-284, ed. T. Garland and A.C. Barr (CAB International). [Full text]
     
  296. a-glucosidase inhibitors as potential broad based anti-viral agents.
    A. Mehta, N. Zitzmann, P.M. Rudd, T.M. Block and R.A. Dwek (1998) FEBS Letters, 430, 17-22. [Full text]
     
  297. Concepts and principles of O-linked glycosylation.
    P. Van den Steen, P.M. Rudd, R.A. Dwek and G. Opdenakker (1998) Crit. Rev. Biochem. Mol. Biol., 33, 151-208. [Full text]
     
  298. Orientation of sugars bound to the principal C-type carbohydrate-recognition domain of the macrophage mannose receptor.
    P.G. Hitchen, N.P. Mullin and M.E. Taylor (1998) Biochem. J., 333, 601-608. [Full text]
     
  299. Quantitation of the oligosaccharides of human serum IgG from patients with rheumatoid arthritis: a critical evaluation of different methods.
    F.H. Routier, E.F. Hounsell, P.M. Rudd, N. Takahashi, A. Bond, F.C. Hay, A. Alavi, J.S. Axford and R. Jefferis (1998) J. Immunol. Methods, 213, 113-130. [Full text]
     
  300. Commentary - New therapeutic prospects for the glycosphingolipid lysosomal storage disease.
    F.M. Platt and T.D. Butters (1998) Biochem. Pharmacology, 56, 421-430. [Full text]
     
  301. Configurational and conformational analysis of highly oxygenated pyrrolizidines : Definitive identification of some naturally occurring 7a-epi-alexines.
    M.R. Wormald, R.J. Nash, P. Hrnciar, J.D. White, R.J. Molyneux and G.W.J. Fleet (1998) Tetrahedron: Asymmetry, 9, 2549-2558. [Full text]
     
  302. Structural determination of N-linked carbohydrates by matrix-assisted laser desorption/ionization mass spectrometry following enzymatic release within sodium dodecyl sulphate polyacrylamide electrophoresis gels: Application to species-specific glycosylation of alpha(1)-acid glycoprotein.
    B. Kuster, A.P. Hunter, S.F. Wheeler, R.A. Dwek and D.J. Harvey (1998) Electrophoresis, 19, 1950-1959. [Full text]
     
  303. Short chain oligogalacturonides induce ethylene production and expression of the gene encoding aminocyclopropane 1-carboxylic acid oxidase in tomato plants.
    S.D. Simpson, D.A. Ashford, D.J. Harvey and D.J. Bowles (1998) Glycobiology, 8, 579-583. [Full text]
     
  304. Functional comparison of two human monocyte chemotactic protein 2 isoforms. Role of the amino-terminal pyroglutamic acid and processing by CD26/dipeptidyl peptidase IV.
    E. van Coillie, P. Proost, I. van Aelst, S. Struyf, M. Polfliet, I. De Meester, D.J. Harvey, J. van Damme and G. Opdenakker (1998) Biochemistry, 37, 12672-12680. [Full text]
     
  305. Evolving views of protein glycosylation.
    K. Drickamer and M.E. Taylor (1998) TIBS, 23, 321-324. [Full text]
     
  306. Use of a conventional point detector to record matrix-assisted laser desorption/ionization spectra from a magnetic sector instrument.
    D.J. Harvey and A.P. Hunter (1998) Rapid Commun. Mass Spectrom., 12, 1721-1726. [Full text]
     
  307. Partially glucose-capped oligosaccharides are found on the hemoglobins of the deep-sea tube worm Riftia pachyptila.
    F. Zal, B. Kuster, B.N. Green, D.J. Harvey and F.H. Lallier (1998) Glycobiology, 8, 663-673. [Full text]
     
  308. Biological importance of glycosylation.
    R.A. Dwek (1998) in “Molecular recognition and inclusion”, pp.1-6, ed. A.W. Coleman (Kluwer Academic Publishers, Netherlands).
     
  309. Sialylated N-glycans in adult rat brain tissue.
    S. Zamze, D.J. Harvey, Y.J. Chen, G.R. Guile, R.A. Dwek and D.R. Wing (1998) Eur. J. Biochem., 258, 243-270. [Full text]
     
  310. MALDI mass spectrometry of carbohydrates on a magnetic sector instrument.
    D.J. Harvey and A.P. Hunter (1998) in “Advances in mass spectrometry, Vol 14”, pp.1-6, ed. E.J. Karalainen, A.E. Hesso, J.E. Jalonen and U.P. Karjalainen (Elsevier).
     
  311. Electrospray ionization-ion trap mass spectrometry for structural analysis of complex N-linked glycoprotein oligosaccharides.
    A.S. Weiskopf, P. Vouros and D.J. Harvey (1998) Anal. Chem., 70, 4441-4447. [Full text]
     
  312. Structural analysis of the CD5 antigen. Expression, disulphide bond analysis and physical characterisation of CD5 scavenger receptor superfamily domain 1.
    M.S.B. McAlister, M.H. Brown, A.C. Willis, P.M. Rudd, D.J. Harvey, R. Aplin, D.M. Shotton, R.A. Dwek, A.N. Barclay and P.C. Driscoll (1998) Eur. J. Biochem., 257, 131-141. [Full text]
     
  313. Identification of highly fucosylated N-linked oligosaccharides from the human parotid gland.
    G.R. Guile, D.J. Harvey, N. O'Donnell, A.K. Powell, A.P. Hunter, S. Zamze, D.L. Fernandes, R.A. Dwek and D.R. Wing (1998) Eur. J. Biochem., 258, 623-656. [Full text]
     
  314. Mechanism of N-acetylgalactosamine binding to a C-type animal lectin carbohydrate-recognition domain.
    A.R. Kolatkar, A.K. Leung, R. Isecke, R. Brossmer, K. Drickamer and W.I. Weis (1998) J. Biol. Chem., 273, 19502-19508. [Full text]
     
  315. The high degree of internal flexibility observed for an oligomannose oligosaccharide is not reproduced in the overall topology of the molecule.
    R.J. Woods, A. Pathiaseril, M.R. Wormald, C.J. Edge and R.A. Dwek (1998) Eur. J. Biochem., 258, 372-386. [Full text]
     
  316. Oligosaccharides of recombinant mouse gelatinase B variants.
    P. Van den Steen, P.M. Rudd, P. Proost, E. Martens, L. Paemen, B. Kuster, J. van Damme, R.A. Dwek and G. Opdenakker (1998) Biochim. Biophys. Acta, 1425, 587-598. [Full text]
     
  317. Biological importance of glycosylation.
    R.A. Dwek (1998) Developments in Biological Standardization, 96, 43-47.
     
  318. A highly cytotoxic L-rhamnose analogue of the antitumour agent spicamycin.
    A. Martin, T.D. Butters and G.W.J. Fleet (1998) Chem. Commun., 19, 2119-2120. [Full text]
     
  319. Picolinyl esters for the structural determination of fatty acids by GC/MS.
    D.J. Harvey (1998) Molecular Biotechnology, 10, 251-260. [Full text]

    1999 - Top-Bottom

  320. Crystal structures of two H-2Db/glycopeptide complexes suggest a molecular basis for CTL cross-reactivity.
    A. Glithero, J. Tormo, J.S. Haurum, G. Arsequell, G. Valencia, J. Edwards, S. Springer, A. Townsend, Y.L. Pao, M.R. Wormald, R.A. Dwek, E.Y. Jones and T. Elliott (1999) Immunity, 10, 63-74. [Full text]
     
  321. Molecular determinants of oligomer formation and complement fixation in mannose-binding proteins.
    R. Wallis and K. Drickamer (1999) J. Biol. Chem., 274, 3580-3589. [Full text]
     
  322. Minireview - Glycosylation and the immune system.
    P.M. Rudd, M.R. Wormald and R.A. Dwek (1999) Trends in Glycoscience and Glycotechnology, 11, 1-21. [Full text]
     
  323. Delayed sympton onset and increased life expectancy in Sandhoff disease mice treated with N-butyldeoxynojirimycin.
    M. Jeyakumar, T.D. Butters, M. Cortina-Borja, V. Hunnam, R.L. Proia, V.H. Perry, R.A. Dwek and F.M. Platt (1999) Proc. Natl. Acad. Sci. USA, 96, 6388-6393. [Full text]
     
  324. A statistical analysis of N- and O-glycan linkage conformations from crystallographic data.
    A.J. Petrescu, S.M. Petrescu, R.A. Dwek and M.R. Wormald (1999) Glycobiology, 9, 343-352. [Full text]
     
  325. Relationship between in-source and post-source fragment ions in the matrix-assisted laser desorption (ionization) mass spectra of carbohydrates recorded with reflectron time-of-flight mass spectrometers.
    D.J. Harvey, A.P. Hunter, R.H. Bateman, J. Brown and G. Critchley (1999) Int. J. Mass Spectrom., 188, 131-146. [Full text]
     
  326. Oligosaccharide analysis and molecular modeling of soluble forms of glycoproteins belonging to the Ly-6, scavenger receptor and immunoglobulin superfamilies expressed in Chinese hamster ovary cells.
    P.M. Rudd, M.R. Wormald, D.J. Harvey, M. Devashayem, M.S.B. McAlister, M.H. Brown, S.J. Davis, A.N. Barclay and R.A. Dwek (1999) Glycobiology, 9, 443-458. [Full text]
     
  327. Absorption, distribution and biotransformation of the cannabinoids.
    D.J. Harvey (1999) in "Marihuana and Medicine", pp.91-103, ed. G.G. Nahas, K.M. Sutin, D.J. Harvey and S. Agurell (Humana Press, New York).
     
  328. Receptor and nonreceptor membrane-mediated effects of THC and cannabinoids.
    G.G. Nahas, D.J. Harvey, K.M. Sutin and S. Agurell (1999) in "Marihuana and Medicine", pp.781-805, ed. G.G. Nahas, K.M. Sutin, D.J. Harvey and S. Agurell (Humana Press, New York).
     
  329. Minireview - Glycoproteins: glycan presentation and protein-fold stability.
    M.R. Wormald and R.A. Dwek (1999) Structure, 7, R155-R160. [Full text]
     
  330. Glycoproteins: rapid sequencing technology for N-linked and GPI anchor glycans.
    P.M. Rudd, T.S. Mattu, N. Zitzmann, A. Mehta, C. Colominas, E. Hart, G. Opdenakker and R.A. Dwek (1999) Biotech. Genetic Eng. Rev., 16, 1-21. [Full text]
     
  331. Molecular analysis of sialoside binding to sialoadhesin by NMR and site-directed mutagenesis.
    P.R. Crocker, M. Vinson, S. Kelm and K. Drickamer (1999) Biochem. J., 341, 355-361. [Full text]
     
  332. Effects of N-butyldeoxynojirimycin and the Lec3.2.8.1 mutant phenotype on N-glycan processing in Chinese hamster ovary cells: Application to glycoprotein crystallization.
    T.D. Butters, L.M. Sparks, K. Harlo, S. Ikemizu, D.I. Stuart, E.Y. Jones and S.J. Davis (1999) Protein Science, 8, 1696-1701. [Full text]
     
  333. Piperidine analogues of D-galactose as potent inhibitors of a-galactosidase: Synthesis by stannane-mediated hydroxymethylation of 5-azido-1,4-lactones. Structural relationships between D-galactosidase and L-rhamnosidase inhibitors.
    J.P. Shilvock, R.J. Nash, A.A. Watson, A.L. Winters, T.D. Butters, R.A. Dwek, D.A. Winkler and G.W.J. Fleet (1999) J. Chem. Soc. Perkin Trans. I, 2747-2754. [Full text]
     
  334. Sugars including erythronic and threonic acids in human aqueous humour.
    J.J. Harding, P. Hassett, K.C. Rixon, A.J. Bron and D.J. Harvey (1999) Current Eye Research, 19, 131-136. [Full text]
     
  335. CD31 (PECAM-1) exists as a dimer and is heavily N-glycosylated.
    J.P. Newton, A.P. Hunter, D.L. Simmons, C.D. Buckley and D.J. Harvey (1999) Biochem. Biophys. Res. Commun., 261, 283-291. [Full text]
     
  336. Tyrosinase folding and copper loading in vivo: a crucial role for calnexin and alpha-glucosidase II.
    N. Branza-Nichita, A.J. Petrescu, R.A. Dwek, M.R. Wormald, F.M. Platt and S.M. Petrescu (1999) Biochem. Biophys. Res. Commun., 261, 720-725. [Full text]
     
  337. Synthesis of homorhamnojirimycins and related trihydroxypipecolic acid derivatives via divergent bicyclic amino lactone intermediates: Inhibition of naringinase (L-rhamnosidase) and dTDP-rhamnose biosynthesis.
    J.P. Shilvock, J.R. Wheatley, R.J. Nash, A.A. Watson, R.C. Griffiths, T.D. Butters, M. Müller, D.J. Watkin, D.A. Winkler and G.W.J. Fleet, (1999) J. Chem. Soc. Perkin Trans. I, 2735-2745. [Full text]
     
  338. Glycosylation of natural human neutrophil gelatinase B and neutrophil gelatinase B-associated lipocalin.
    P.M. Rudd, T.S. Mattu, S. Masure, T. Bratt, P.E. Van den Steen, M.R. Wormald, B. Kuster, D.J. Harvey, N. Borregaard, J. van Damme, R.A. Dwek and G. Opdenakker (1999) Biochemistry, 38, 13937-13950. [Full text]
     
  339. Synthesis and biological evaluation of enantiomeric rhamnose analogues of the antitumour agent spicamycin - is the mode of action by modification of N-linked glycoproteins?
    A. Martin, T.D. Butters and G.W.J. Fleet (1999) Tetrahedron: Asymmetry, 10, 2343-2360. [Full text]
     
  340. Imino sugars inhibit the formation and secretion of bovine viral diarrhea virus, a pestivirus model of hepatitis C virus: Implications for the development of broad spectrum anti-hepatitis virus agents.
    N. Zitzmann, A.S. Mehta, S. Carrouée, T.D. Butters, F.M. Platt, J. McCauley, B.S. Blumberg, R.A. Dwek and T.M. Block (1999) Proc. Natl. Acad. Sci. USA, 96, 11878-11882. [Full text]
     
  341. Editorial overview - Carbohydrates and glycoconjugates.
    A. Imberty and K. Drickamer (1999) Curr. Op. Struc. Biol., 9, 547-548. [Full text]
     
  342. C-type lectin-like domains.
    K. Drickamer (1999) Curr. Op. Struc. Biol., 9, 585-590. [Full text]
     
  343. Roles for glycosylation of cell surface receptors involved in cellular immune recognition.
    P.M. Rudd, M.R. Wormald, R.L. Stanfield, M. Huang, N. Mattson, J.A. Speir, J.A. DiGennaro, J.S. Fetrow, R.A. Dwek and I.A. Wilson (1999) J. Mol. Biol., 293, 351-366. [Full text]
     
  344. Molecular defects in variant forms of mannose-binding protein associated with immunodeficiency.
    R. Wallis and J.Y.T. Cheng (1999) J. Immunol., 163, 4953-4959. [Full text]
     
  345. Multiple interactions between pituitary hormones and the mannose receptor.
    D.Z. Simpson, P.G. Hitchen, E.L. Elmhirst and M.E. Taylor (1999) Biochem. J., 343, 403-411. [Full text]
     
  346. Glycosylation differences between the normal and pathogenic prion protein isoforms.
    P.M. Rudd, T. Endo, C. Colominas, D. Groth, S.F. Wheeler, D.J. Harvey, M.R. Wormald, H. Serban, S.B. Prusiner, A. Kobata and R.A. Dwek (1999) Proc. Natl. Acad. Sci. USA, 96, 13044-13049. [Full text]
     
  347. Sugar printing rheumatic diseases - A potential method for disease differentiation using immunoglobulin G oligosaccharides.
    M. Watson, P.M. Rudd, M. Bland, R.A. Dwek and J.S. Axford (1999) Arthritis and Rheumatism, 42, 1682-1690. [Full text]
     
  348. Glycosylation of a CNS-specific extracellular matrix glycoprotein, tenascin-R, is dominated by O-linked sialylated glycans and "brain-type" neutral glycans.
    S. Zamze, D.J. Harvey, P. Pesheva, T.S. Mattu, M. Schachner, R.A. Dwek and D.R. Wing (1999) Glycobiology, 9, 823-831. [Full text]
     
  349. Polyhydroxylated pyrrolidine and pyrrolizidine alkaloids from Hyacinthoides non-scripta and Scilla campanulata.
    A. Kato, I. Adachi, M. Miyauchi, K. Ikeda, T. Komae, H. Kizu, Y. Kameda, A.A. Watson, R.J. Nash, M.R. Wormald, G.W.J. Fleet and N. Asano (1999) Carbohydr. Res., 316, 95-103. [Full text]
     
  350. Identification of Amino Acid Residues That Determine pH Dependence of Ligand Binding to the Asialoglycoprotein Receptor during Endocytosis.
    S. Wragg and K. Drickamer (1999) J. Biol. Chem., 274, 35400-35406. [Full text]
     
  351. C-Type lectin-like domains in Caenorhabditis elegans: predictions from the complete genome sequence.
    K. Drickamer and R.B. Dodd (1999) Glycobiology, 9, 1357-1369. [Full text]
     
  352. Exploring functions for glycosylation in host defence using novel oligosaccharide sequencing technology.
    P.M. Rudd, M.R. Wormald and R.A. Dwek (1999) in “Proteome and protein analysis”, pp.321-339, ed. R.M. Kamp, D. Kyriakidis and T. Choli-Papadopoulou (Springer-Verlag). [Full text]
     
  353. Cell-specific Glycoforms of Sialoadhesin and CD45 Are Counter-receptors for the Cysteine-rich Domain of the Mannose Receptor.
    L. Martinez-Pomares, P.R. Crocker, R. Da Silva, N. Holmes, C. Colominas, P.M. Rudd, R.A. Dwek and S. Gordon (1999) J. Biol. Chem., 274, 35211-35218. [Full text]
     
  354. The glycan processing and site occupancy of recombinant Thy-1 is markedly affected by the presence of a glycosylphosphatidylinositol anchor.
    M. Devasahayam, P.D. Catalino, P.M. Rudd, R.A. Dwek and A.N. Barclay (1999) Glycobiology, 9, 1381-1387. [Full text]
     
  355. Matrix-assisted laser desorption/ionization mass spectrometry of carbohydrates.
    D.J. Harvey (1999) Mass Spectrom. Rev., 18, 349-451. [Full text]
     
  356. Protein specific N-glycosylation of tyrosinase and tyrosinase-related protein-1 in B16 mouse melanoma cells.
    G. Negroiu, N. Branza-Nichita, A.J. Petrescu, R.A. Dwek and S.M. Petrescu (1999) Biochem. J., 344, 659-665. [Full text]
     
  357. Synthesis of bis(1,3-Dihydroxy-isopropyl)amine by reductive amination of dihydroxyacetone: open chain equivalent of DMDP and a potential AB4 dendritic monomer.
    D.A. Scott, T.M. Krülle, M. Finn, R.J. Nash, A.L. Winters, N. Asano, T.D. Butters and G.W.J. Fleet (1999) Tetrahedron Letters, 40, 7581-7584. [Full text]
     
  358. Investigation of the intracellular transport of tyrosinase and tyrosinase related protein (TRP)-1. The effect of endoplasmic reticulum (ER)-glucosidases inhibition.
    G. Negroiu, N. Branza-Nichita, G.E. Costin, H. Titu, A.J. Petrescu, R.A. Dwek and S.M. Petrescu (1999) Cell. Mol. Biol., 45, 1001-1010. [Abstract]
     
  359. Characterisation of tissue-specific oligosaccharides from rat brain and kidney membrane preparations enriched in Na+,K+-ATPase.
    R.A.C. Clark, B. Kuster, M. Benallal, B.M. Anner, R.A. Dwek, D.J. Harvey and D.R. Wing (1999) Glycoconj. J., 16, 437-456. [Full text]
     
  360. Evolution of C-type lectin-like domains.
    K. Drickamer (1999) in "Perspectives in structural biology: a volume in honour of G.N. Ramachandran", pp. 380-391, ed. M. Vijayan, N. Yathindra and A.S. Kolaskar (Universities Press (India) Ltd., Hyderabad).
     
  361. Protein glycosylation.
    D.A. Ashford and F.M. Platt (1999) in "Post-translational processing - a practical approach", pp. 135-174, ed. S.J. Higgins and B.D. Hames (Oxford University Press).
     
  362. Analysis of the carbohydrate components of glycosylphosphatidylinositol structures using fluorescent labeling.
    N. Zitzmann and M.A.J. Ferguson (1999) in "Protein Lipidation Protocols", Methods in Molecular Biology, 116, pp. 73-89, ed. M.H. Gelb (Humana). [Full text]

    2000 - Top-Bottom

  363. Matrix-assisted laser desorption/ionization mass spectrometry of N-linked carbohydrates and related compounds.
    D.J. Harvey, B. Kuster, S.F. Wheeler, A.P. Hunter, R.H. Bateman and R.A. Dwek (2000) in "Mass Spectrometry in Biology and Medicine", pp.407-437, ed. A.L. Burlingame, S.A. Carr and M.A. Baldwin (Humana Press, Totowa, NJ).
     
  364. Hybrid and complex glycans are linked to the conserved N-glycosylation site of the third eight-cysteine domain of LTBP-1 in insect cells.
    P.M. Rudd, A.K. Downing, M. Cadene, D.J. Harvey, M.R. Wormald, I. Weir, R.A. Dwek, D.B. Rifkin and P.E. Gleizes (2000) Biochemistry, 39, 1596-1603. [Full text]
     
  365. Two edged role of mannose binding lectin in rheumatoid arthritis: a cross sectional study.
    P. Garred, H.O. Madsen, H. Marquart, T.M. Hansen, S.F. Sorensen, J. Petersen, B. Volck, A. Svejgaard, N.A. Graudal, P.M. Rudd, R.A. Dwek, R.B. Sim and V. Andersen (2000) J. Rheumatol., 27, 26-34. [Abstract]
     
  366. N-butyldeoxygalactonojirimycin: A more selective inhibitor of glycosphingolipid biosynthesis than N-butyldeoxynojirimycin, in vitro and in vivo.
    U. Andersson, T.D. Butters, R.A. Dwek and F.M. Platt (2000) Biochemical Pharmacology, 59, 821-829. [Full text]
     
  367. Protein structure controls the processing of the N-linked oligosaccharides and glycosylphosphatidylinositol glycans of variant surface glycoproteins expressed in bloodstream form Trypanosoma brucei.
    N. Zitzmann, A. Mehlert, S. Carrouée, P.M. Rudd and M.A.J. Ferguson (2000) Glycobiology, 10, 243-249. [Full text]
     
  368. Electrospray mass spectrometry and collision-induced fragmentation of 2-aminobenzamide-labeled neutral N-linked glycans.
    D.J. Harvey (2000) The Analyst, 125, 609-617. [Full text]
     
  369. Molecular requirements of imino sugars for the selective control of N-linked glycosylation and glycosphingolipid biosynthesis.
    T.D. Butters, L.A.G.M. van den Broek, G.W.J. Fleet, T.M. Krulle, M.R. Wormald, R.A. Dwek and F.M. Platt (2000) Tetrahedron: Asymmetry, 11, 113-124. [Full text]
     
  370. Mutations at critical N-glycosylation sites reduce tyrosinase activity by altering folding and quality control.
    N. Branza-Nichita, G. Negroiu, A.J. Petrescu, E.F. Garman, F.M. Platt, M.R. Wormald, R.A. Dwek and S.M. Petrescu (2000) J. Biol. Chem., 275, 8169-8175. [Full text]
     
  371. Substrate deprivation: A new therapeutic approach for the glycosphingolipid lysosomal storage diseases.
    F.M. Platt and T.D. Butters (2000) Exp. Rev. Mol. Med., 1 February, (00)00148-4a. [Full text]
     
  372. Post-source decay fragmentation of N-linked carbohydrates from ovalbumin and related glycoproteins.
    D.J. Harvey (2000) J. Am. Soc. Mass Spectrom., 11, 572-577. [Full text]
     
  373. Composition of N-linked carbohydrates from ovalbumin and co-purified glycoproteins.
    D.J. Harvey, D.R. Wing, B. Kuster and I.B.H. Wilson (2000) J. Am. Soc. Mass Spectrom., 11, 564-571. [Full text]
     
  374. Novel oral treatment of Gaucher's disease with N-butyldeoxynojirimycin (OGT 918) to decrease substrate biosynthesis.
    T. Cox, R. Lachmann, C. Hollak, J.M.F.G. Aerts, S. van Weely, M. Hrebícek, F.M. Platt, T.D. Butters, R.A. Dwek, C. Moyses, I. Gow, D. Elstein and A. Zimran (2000) Lancet, 355, 1481-1485. [Full text]
     
  375. N-2-(Diethylamino)ethyl-4-aminobenzamide derivatives for high sensitivity mass spectrometric detection and structure determination of N-linked carbohydrates.
    D.J. Harvey (2000) Rapid Commun. Mass Spectrom., 14, 862-871. [Full text]
     
  376. Tyrosinase and glycoprotein folding: Roles of chaperones that recognize glycans.
    S.M. Petrescu, N. Branza-Nichita, G. Negroiu, A.J. Petrescu and R.A. Dwek (2000) Biochemistry, 39, 5229-5237. [Full text]
     
  377. Letter to GlycoForum - Imino sugar therapy for type 1 Gaucher disease.
    D.A. Priestman, F.M. Platt, R.A. Dwek and T.D. Butters (2000) Glycobiology, 10, iv-vi.
     
  378. Hepatitis C virus glycoprotein E2 binding to CD81: The role of E1E2 cleavage and protein glycosylation in bioactivity.
    C. Chan-Fook, W-R. Jiang, B.E. Clarke, N. Zitzmann, C. Maidens, J.A. McKeating and I.M. Jones (2000) Virology, 273, 60-66. [Full text]
     
  379. Minireview - O-linked glycosylation in focus.
    P.E. Van den Steen, P.M. Rudd, M.R. Wormald, R.A. Dwek and G. Opdenakker (2000) Trends in Glycoscience and Glycotechnology, 12, 35-49. [Full text]
     
  380. High-performance cation-exchange chromatography and pulsed amperometric detection for the separation, detection, and quantitation of N-alkylated imino sugars in biological samples.
    H.R. Mellor, A. Adam, F.M. Platt, R.A. Dwek and T.D. Butters (2000) Anal. Biochem., 284, 136-142. [Full text]
     
  381. Influence of baculovirus-host cell interactions on complex N-linked glycosylation of a  recombinant human protein.
    L. Joshi, T.R. Davis, T.S. Mattu, P.M. Rudd, R.A. Dwek, M.L. Shuler and H.A. Wood (2000) Biotechnol. Prog., 16, 650-656. [Full text]
     
  382. Structure of a C-type carbohydrate recognition domain from the macrophage mannose receptor.
    H. Feinberg, S. Park-Snyder, A.R. Kolatkar, C.T. Heise, M.E. Taylor and W.I. Weis (2000) J. Biol. Chem., 275, 21539-21548. [Full text]
     
  383. Ionization and fragmentation of complex glycans with a Q-TOF mass spectrometer fitted with a MALDI ion source.
    D.J. Harvey, R.H. Bateman, R.S. Bordoli and R. Tyldesley (2000) Rapid Commun. Mass Spectrom., 14, 2135-2142. [Full text]
     
  384. Collision-induced fragmentation of underivatised N-linked carbohydrates ionized by electrospray.
    D.J. Harvey (2000) J. Mass Spectrom., 35, 1178-1190. [Full text]
     
  385. Negative ion mass spectrometry of sialylated carbohydrates: Discrimination of N-acetylneuraminic acid linkages by MALDI-TOF and ESI-TOF mass spectrometry.
    S.F. Wheeler and D.J. Harvey (2000) Anal. Chem., 72, 5027-5039. [Full text]
     
  386. Electrospray mass spectrometry and fragmentation of N-linked carbohydrates derivatised at the reducing terminus.
    D.J. Harvey (2000) J. Am. Soc. Mass Spectrom., 11, 900-915. [Full text]
     
  387. Folding and maturation of tyrosinase-related protein-1 are regulated by the post-translational formation of disulfide bonds and by N-glycan processing.
    G. Negroiu, R.A. Dwek and S.M. Petrescu (2000) J. Biol. Chem., 275, 32200-32207. [Full text]
     
  388. Assay for the transbilayer distribution of glycolipids: selective oxidation of glucosylceramide to glucuronylceramide by TEMPO nitroxyl radicals.
    D.J. Sillence, R.J. Raggers, D.C.A. Neville, D.J. Harvey and G. Van Meer (2000) J. Lipid Res., 41, 1252-1260. [Full text]
     
  389. Interaction of mannose-binding protein with associated serine proteases - Effects of naturally occurring mutations.
    R. Wallis and R.B. Dodd (2000) J. Biol. Chem., 275, 30962-30969. [Full text]
     
  390. Impaired secretion of rat mannose-binding protein resulting from mutations in the collagen-like domain
    C.T. Heise, J.R. Nicholls, C.E. Leamy and R. Wallis (2000) J. Immunol., 165, 1403-1409. [Full text]
     
  391. Sugar binding in innate immunity.
    K. Drickamer, M.E. Taylor and R. Wallis (2000) Wellcome Trust Rev., 9, 38-40. [Full text]
     
  392. Glycosylation and glycoprotein folding.
    S.M. Petrescu, A.J. Petrescu, F.M. Platt and R.A. Dwek (2000) Wellcome Trust Rev., 9, 41-42. [Full text]
     
  393. O-glycan analysis of natural human neutrophil gelatinase B using a combination of normal phase-HPLC and online tandem mass spectrometry: implications for the domain organization of the enzyme.
    T.S. Mattu, L. Royle, J. Langridge, M.R. Wormald, P.E. Van den Steen, J. Van Damme, G. Opdenakker, D.J. Harvey, R.A. Dwek and P.M. Rudd (2000) Biochemistry, 39, 15965-15704. [Full text]
     
  394. Inhibition of glycosphingolipid biosynthesis: application to lysosomal storage disorders.
    T.D. Butters, R.A. Dwek and F.M. Platt (2000) Chemical Reviews, 100, 4683-4696. [Full text]
     
  395. N-glycosylation processing and glycoprotein folding - lessons from the tyrosinase-related proteins.
    N. Branza-Nichita, A.J. Petrescu, G. Negroiu, R.A. Dwek and S.M. Petrescu (2000) Chemical Reviews, 100, 4697-4711. [Full text]
     
  396. Fluorescence labelling of carbohydrates with 2-aminobenzamide (2AB).
    R.R. France, I. Cumpstey, T.D. Butters, A.J. Fairbanks and M.R. Wormald (2000) Tetrahedron: Asymmetry, 11, 4985-4994. [Full text]
     
  397. Rapid sensitive HPLC based strategies for analysis of N- and O-linked oligosaccharides attached to 5-20 micrograms of glycoproteins.
    P.M. Rudd, T.S. Mattu, M.R. Wormald, D.J. Harvey and R.A. Dwek (2000) in "Pharmeuropa, Biologicals Beyond 2000", pp.103-118 (European Directorate for the Quality of Medicines). [Full text]
     
  398. Mechanism of pH-dependent N-acetylgalactosamine binding by a functional mimic of the hepatocyte asialoglycoprotein receptor.
    H. Feinberg, D. Torgersen, K. Drickamer and W.I. Weis (2000) J. Biol. Chem., 275, 35176-35184. [Full text]
     
  399. Determining the structure of oligosaccharides N- and O-linked to glycoproteins.
    P.M. Rudd and R.A. Dwek (2000) in "Current Protocols in Protein Science", pp.12.6.1-12.6.47 (John Wiley).
     
  400. Determining the structure of glycan moieties by mass spectrometry.
    D.J. Harvey, R.A. Dwek and P.M. Rudd (2000) in "Current Protocols in Protein Science", pp.12.7.1-12.7.15 (John Wiley).

    2001 - Top-Bottom

  401. Glycoproteomics: high-throughput sequencing of oligosaccharide modifications to proteins.
    P.M. Rudd, C. Colominas, L. Royle, N. Murphy, E. Hart, A.H. Merry, H.F. Hebestreit and R.A. Dwek (2001) in "Proteome Research: Mass Spectrometry", pp.207-228, ed. P. James (Springer, Heidelberg).
     
  402. Enhanced survival in Sandhoff disease mice receiving a combination of substrate deprivation therapy and bone marrow transplantation.
    M. Jeyakumar, F. Norflus, C.J. Tifft, M. Cortina-Borja, T.D. Butters, R.L. Proia, V.H. Perry, R.A. Dwek and F.M. Platt (2001) Blood, 97, 327-329. [Full text]
     
  403. Structure and function of the macrophage mannose receptor.
    M.E. Taylor (2001) in "Mammalian Carbohydrate Recognition Systems", Results and Problems in Cell Differentiation - Volume 33, pp.105-121, ed. P.R. Crocker (Springer, Berlin).
     
  404. Identification of protein-bound carbohydrates by mass spectrometry.
    D.J. Harvey (2001) Proteomics, 1, 311-328. [Full text]
     
  405. Glycosylation analysis of gel separated proteins.
    B. Kuster, T.N. Krogh, E. Mørtz and D.J. Harvey (2001) Proteomics, 1, 350-361. [Full text]
     
  406. Substrate reduction therapy for glycosphingolipid storage disorders.
    R.H. Lachmann and F.M. Platt (2001) Expert Opinion on Investigational Drugs, 10, 455-466. [Full text]
     
  407. Antiviral effect of N-butyldeoxynojirimycin against bovine viral diarrhea virus correlates with misfolding of E2 envelope proteins and impairment of their association into E1-E2 heterodimers.
    N. Branza-Nichita, D. Durantel, S. Carrouée-Durantel, R.A. Dwek and N. Zitzmann (2001) J. Virology, 75, 3527-3536. [Full text]
     
  408. Prion glycoprotein: structure, dynamics, and roles for the sugars.
    P.M. Rudd, M.R. Wormald, D.R. Wing, S.B. Prusiner and R.A. Dwek (2001) Biochemistry, 40, 3759-3766. [Full text]
     
  409. Glycosylation and the immune system.
    P.M. Rudd, T. Elliott, P. Cresswell, I.A. Wilson and R.A. Dwek (2001) Science, 291, 2370-2376. [Full text]
     
  410. A high-performance liquid chromatography based strategy for rapid, sensitive sequencing of N-linked oligosaccharide modifications to proteins in sodium dodecyl sulphate polyacrylamide electrophoresis gel bands.
    P.M. Rudd, C. Colominas, L. Royle, N. Murphy, E. Hart, A.H. Merry, H.F. Hebestreit and R.A. Dwek (2001) Proteomics, 1, 285-294. [Full text]
     
  411. Carbopeptoids: peptides and diketopiperazines incorporating the anomeric centre of mannopyranose.
    D.D. Long, R.J. Tennant-Eyles, J.C. Estevez, M.R. Wormald, R.A. Dwek, M.D. Smith and G.W.J. Fleet (2001) J. Chem. Soc. Perkin Trans. I, 807-813. [Full text]
     
  412. Inhibition of hepatitis B virus DNA replication by imino sugars without the inhibition of the DNA polymerase: Therapeutic implications.
    A. Mehta, S. Carrouée, B. Conyers, R. Jordan, T.D. Butters, R.A. Dwek and T.M. Block (2001) Hepatology, 33, 1488-1495. [Full text]
     
  413. An extended conformation of the macrophage mannose receptor.
    C.E. Napper, M.H. Dyson and M.E. Taylor (2001) J. Biol. Chem., 276, 14759-14766. [Full text]
     
  414. Inhibition of substrate synthesis as a strategy for glycolipid lysosomal storage disease therapy.
    F.M. Platt, M. Jeyakumar, U. Andersson, D.A. Priestman, R.A. Dwek, T.D. Butters, T.M. Cox, R.H. Lachmann, C. Hollak, J.M.F.G. Aerts, S. Van Weely, M. Hrebicek, C. Moyses, I. Gow, D. Elstein and A. Zimran (2001) J. Inherit. Metab. Dis., 24, 275-290. [Full text]
     
  415. Crystal structure of a neutralizing human IgG against HIV-1: a template for vaccine design.
    E.O. Saphire, P.W.H.I. Parren, R. Pantophlet, M.B. Zwick, G.M. Morris, P.M. Rudd, R.A. Dwek, R.L. Stanfield, D.R. Burton and I.A. Wilson (2001) Science, 293, 1155-1159. [Full text]
     
  416. Antibodies inhibit prion propagation and clear cell cultures of prion infectivity.
    D. Peretz, R.A. Williamson, K. Kaneko, J. Vergara, E. Leclerc, G. Schmitt-Uims, I.R. Mehlhorn, G. Legname, M.R. Wormald, P.M. Rudd, R.A. Dwek, D.R. Burton and S.B. Prusiner (2001) Nature, 412, 739-743. [Full text]
     
  417. A family of novel, acidic N-glycans in Bowes melanoma tissue plasminogen activator have L2/HNK-1-bearing antennae, many with sulfation of the fucosylated chitobiose core.
    S. Zamze, D.R. Wing, M.R. Wormald, A.P. Hunter, R.A. Dwek and D.J. Harvey (2001) Eur. J. Biochem., 268, 4063-4078. [Full text]
     
  418. Carbohydrate receptor depletion as an antimicrobial strategy for prevention of urinary tract infection.
    M. Svensson, F.M. Platt, B. Frendeus, T.D. Butters, R.A. Dwek and C. Svanborg (2001) J. Infectious Diseases, 183, S70-S73. [Full text]
     
  419. Structural elucidation of the N- and O-glycans of human apolipoprotein(a) - Role of O-glycans in conferring protease resistance.
    B. Garner, A.H. Merry, L. Royle, D.J. Harvey, P.M. Rudd and J. Thillet (2001) J. Biol. Chem., 22200-22208. [Full text]
     
  420. Minireview - Lectin-like proteins in model organisms: implications for evolution of carbohydrate-binding activity.
    R.B. Dodd and K. Drickamer (2001) Glycobiology, 11, 71R-79R. [Full text]
     
  421. N-butyldeoxynojirimycin reduces growth and ganglioside content of experimental mouse brain tumours.
    M.K. Ranes, M. El-Abbadi, M.G. Manfredi, P. Mukherjee, F.M. Platt and T.N. Seyfried (2001) Brit. J. Cancer, 84, 1107-1114. [Full text]
     
  422. Study of the mechanism of antiviral action of iminosugar derivatives against Bovine Viral Diarrhea Virus.
    D. Durantel, N. Branza-Nichita, S. Carrouée-Durantel, T.D. Butters, R.A. Dwek and N. Zitzmann (2001) J. Virology, 75, 8987-8998. [Full text]
     
  423. Extension of the in-gel release method for structural analysis of neutral and sialylated N-linked glycans to the analysis of sulfated glycans: Application to the glycans from bovine thyroid-stimulating hormone.
    S.F. Wheeler and D.J. Harvey (2001) Anal. Biochem., 296, 92-100. [Full text]
     
  424. Ionization and collision-induced fragmentation of N-linked and related carbohydrates using divalent cations.
    D.J. Harvey (2001) J. Am. Soc. Mass Spectrom., 12, 926-937. [Full text]
     
  425. Proteomics: an holistic analysis of nature's proteins.
    H.F. Hebestreit (2001) Curr. Op. Pharmacol., 1, 513-520. [Full text]
     
  426. Hepatitis B virus MHBs antigen is selectively sensitive to glucosidase-mediated processing in the endoplasmic reticulum.
    X.Y. Lu, Y.F. Lu, R. Geschwindt, R.A. Dwek and T.M. Block (2001) DNA Cell Biol., 20, 647-656. [Full text]
     
  427. RNA replication kinetics, genetic polymorphism and selection in the case of the hepatitis C virus.
    M.P.H. Stumpf and N. Zitzmann (2001) Proc. R. Soc. Lond. B., 268, 1993-1999. [Full text]
     
  428. Effect of reducing-terminal derivatization on the fragmentation of N-linked carbohydrates.
    D.J. Harvey and L. Royle (2001) in "Advances in Mass Spectrometry, vol. 15", pp.553-554, ed. E. Gelpi (John Wiley).
     
  429. A novel mechanism of carbohydrate recognition by the C-type lectins DC-SIGN and DC-SIGNR - Subunit organization and binding to multivalent ligands.
    D.A. Mitchell, A.J. Fadden and K. Drickamer (2001) J. Biol. Chem., 276, 28939-28945. [Full text]
     
  430. News and Views - Holistic approaches to glycobiology.
    P.M. Rudd, G. Opdenakker and R.A. Dwek (2001) Nature Biotechnology, 19, 531-532. [Full text]
     
  431. Matrix remodelling enzymes, the protease cascade and glycosylation.
    P.E. Van den Steen, G. Opdenakker, M.R. Wormald, R.A. Dwek and P.M. Rudd (2001) Biochim. Biophys. Acta, 1528, 61-73. [Full text]
     
  432. High-performance liquid chromatography anlysis of ganglioside carbohydrates at the picomole level after ceramide glycanase digestion and fluorescent labeling with 2-aminobenzamide.
    D.R. Wing, B. Garner, V. Hunnam, G. Reinkensmeier, U. Andersson, D.J. Harvey, R.A. Dwek, F.M. Platt and T.D. Butters (2001) Anal. Biochem., 298, 207-217. [Full text]
     
  433. Characterization of human apolipoprotein B100 oligosaccharides in LDL subfractions derived from normal and hyperlipidemic plasma: deficiency of alpha-N-acetylneuraminyllactosyl-ceramide in light and small dense LDL particles.
    B. Garner, D.J. Harvey, L. Royle, M. Frischmann, F. Nigon, M.J. Chapman and P.M. Rudd (2001) Glycobiology, 11, 791-802. [Full text]
     
  434. Ionization and fragmentation of neutral and acidic glycosphingolipids with a Q-TOF mass spectrometer fitted with a MALDI ion source.
    V. Hunnam, D.J. Harvey, D.A. Priestman, R.H. Bateman, R.S. Bordoli and R. Tyldesley (2001) J. Am. Soc. Mass Spectrom., 12, 1220-1225. [Full text]
     
  435. Synovial stimulatory protein fragments copurify with woodchuck hepatitis virus: Implications for the etiology of arthritis in chronic hepatitis B virus infection.
    A.S. Mehta, X.Y. Lu, T.M. Block, A.C. Willis, R.A. Dwek, B. Tennant and B.S. Blumberg (2001) Arthritis and Rheumatism, 44, 468-489. [Full text]
     
  436. Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O-2-regulated prolyl hydroxylation.
    P. Jaakkola, D.R. Mole, Y.M. Tian, M.I. Wilson, J. Gielbert, S.J. Gaskell, A. von Kriegsheim, H.F. Hebestreit, M. Mukherji, C.J. Schofield, P.H. Maxwell, C.W. Pugh and P.J. Ratcliffe (2001) Science, 292, 468-472. [Full text]
     
  437. Proteomics: A new concept for pharmaceutical research?
    H.F. Hebestreit and R.A. Dwek (2001) Eur. Pharmaceutical Rev., 2, 23-33.
     
  438. Stoichiometry of complexes between mannose-binding protein and its associated serine proteases.
    C.B. Chen and R. Wallis (2001) J. Biol. Chem., 276, 25894-25902. [Full text]
     
  439. A proteomic approach for the discovery of early detection markers of hepatocellular carcinoma.
    L.F. Steel, T.S. Mattu, A. Mehta, H.F. Hebestreit, R.A. Dwek, A.A. Evans, W.T. London and T. Block (2001) Disease Markers, 17, 179-189. [Full text]
     
  440. Structural basis for selective recognition of oligosaccharides by DC-SIGN and DC-SIGNR.
    H. Feinberg, D.A. Mitchell, K. Drickamer and W.I. Weis (2001) Science, 294, 2163-2166. [Full text]
     
  441. Minimal requirements for the binding of selectin ligands to a C-type carbohydrate-recognition domain.
    S. Bouyain, S. Rushton and K. Drickamer (2001) Glycobiology, 11, 989-996. [Full text]
     
  442. Nucleoside diphosphate kinase III is localized to the inter-membrane space in plant mitochondria.
    L.J. Sweetlove, B. Mowday, H.F. Hebestreit, C.J. Leaver and A.H. Millar (2001) FEBS Letters, 508, 272-276. [Full text]
     
  443. Complex encounters at the macrophage-mycobacterium interface: Studies on the role of the mannose receptor and CD14 in experimental infection models with Mycobacterium avium.
    N. Reiling, K. Klug, U. Krallmann-Wenzel, R. Laves, S. Goyert, M.E. Taylor, T.K. Lindhorst and S. Ehlers (2001) Immunobiology, 204, 558-571. [Full text]
     
  444. The chemical and enzymatic hydrolysis of archaeological wood cellulose and monosaccharide purification by high pH anion exchange chromatography for compound-specific radiocarbon dating.
    G.W.L. Hodgins, T.D. Butters, C.B. Ramsey and R.E.M. Hedges (2001) Radiocarbon, 43, 209-215. [Full text]
     
  445. Apoptosis and signalling in acid sphingomyelinase deficient cells.
    D.J. Sillence (2001) BMC Cell Biol., 2: art. no. 24. [Full text]

    2002 - Top-Bottom

  446. Targeting glycosylation as a therapeutic approach.
    R.A. Dwek, T.D. Butters, F.M. Platt and N. Zitzmann (2002) Nature Reviews Drug Discovery, 1, 65-75. [Full text]
     
  447. Localization and characterization of polysialic acid-containing N-linked glycans from bovine N-CAM.
    M. von der Ohe, S.F. Wheeler, M. Wuhrer, D.J. Harvey, S. Liedke, R. Gerardy-Schahn, H. Geyer, R. Geyer, R.A. Dwek, D.R. Wing and M. Schachner (2002) Glycobiology, 12, 47-63. [Full text]
     
  448. Editorial - Introduction: Glycobiology-Understanding the Language and Meaning of Carbohydrates.
    R.A. Dwek and T.D. Butters (2002) Chemical Reviews, 102, 283-284. [Full text]
     
  449. Glycosylation and the complement system.
    G.E. Ritchie, B.E. Moffatt, R.B. Sim, B.P. Morgan, R.A. Dwek and P.M. Rudd (2002) Chemical Reviews, 102, 305-319. [Full text]
     
  450. Conformational studies of oligosaccharides and glycopeptides: Complementarity of NMR, X-ray crystallography, and molecular modelling.
    M.R. Wormald, A.J. Petrescu, Y.L. Pao, A. Glithero, T. Elliott and R.A. Dwek (2002) Chemical Reviews, 102, 371-386. [Full text]
     
  451. Identifying protein production in wound healing: current techniques.
    J.M. Pleat, H.F. Hebestreit and R.A. Dwek (2002) J. Wound Care, 11, 63-66. [Full text]
     
  452. The carbohydrate moiety of serum IgM from Atlantic cod (Gadus morhua L.).
    B. Magnadottir, M. Crispin, L. Royle, C. Colominas, D.J. Harvey, R.A. Dwek and P.M. Rudd (2002) Fish Shellfish Immunol., 12, 209-227. [Full text]
     
  453. "Internal residue loss": Rearrangements occurring during the fragmentation of carbohydrates derivatized at the reducing terminus.
    D.J. Harvey, T.S. Mattu, M.R. Wormald, L. Royle, R.A. Dwek and P.M. Rudd (2002) Anal. Chem., 74, 734-740. [Full text]
     
  454. Capillary electrophoresis/electrospray ion trap mass spectrometry for the analysis of negatively charged derivatized and underivatized glycans.
    L.A. Gennaro, J. Delaney, P. Vouros, D.J. Harvey and B. Domon (2002) Rapid Commun. Mass Spectrom., 16, 192-200. [Full text]
     
  455. Structural analysis of oligosaccharides by atmospheric pressure matrix assisted laser desorption/ionization-quadrupole ion trap mass spectrometry.
    C.S. Creaser, J.C. Reynolds and D.J. Harvey (2002) Rapid Commun. Mass Spectrom., 16, 176-184. [Full text]
     
  456. Modulation of THP-1 macrophage and cholesterol-loaded foam cell apolipoprotein E levels by glycosphingolipids.
    B. Garner, H.R. Mellor, T.D. Butters, R.A. Dwek and F.M. Platt (2002) Biochem. Biophys. Res. Commun., 290, 1361-1367. [Full text]
     
  457. An analytical and structural database provides a strategy for sequencing O-glycans from microgram quantities of glycoproteins.
    L. Royle, T.S. Mattu, E. Hart, J.I. Langridge, A.H. Merry, N. Murphy, D.J. Harvey, R.A. Dwek and P.M. Rudd (2002) Anal. Biochem., 304, 70-90. [Full text]
     
  458. Recovery of intact 2-aminobenzamide-labeled O-glycans released from glycoproteins by hydrazinolysis.
    A.H. Merry, D.C.A. Neville, L. Royle, B. Matthews, D.J. Harvey, R.A. Dwek and P.M. Rudd (2002) Anal. Biochem., 304, 91-99. [Full text]
     
  459. Increased glycosphingolipid levels in serum and aortae of apolipoprotein E gene knockout mice.
    B. Garner, D.A. Priestman, R. Stocker, D.J. Harvey, T.D. Butters and F.M. Platt (2002) J. Lipid Res., 43, 205-214. [Full text]
     
  460. Towards complete analysis of the platelet proteome.
    E.E. O'Neill, C.J. Brock, A.F. von Kriegsheim, A.C. Pearce, R.A. Dwek, S.P. Watson and H.F. Hebestreit (2002) Proteomics, 2, 288-305. [Full text]
     
  461. Antiviral effects of an iminosugar derivative on flavivirus infections.
    S.F. Wu, C.J. Lee, C.L. Liao, R.A. Dwek, N. Zitzmann and Y.L. Lin (2002) J. Virology, 76, 3596-3604. [Full text]
     
  462. Dominant effects of mutations in the collagenous domain of mannose-binding protein.
    R. Wallis (2002) J. Immunol., 168, 4553-4558. [Full text]
     
  463. The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of a1-2 mannose residues on the outer face of gp120.
    C.N. Scanlan, R. Pantophlet, M.R. Wormald, E.O. Saphire, R.L. Stanfield, I.A. Wilson, H. Katinger, R.A. Dwek, P.M. Rudd and D.R. Burton (2002) J. Virology, 76, 7306-7321. [Full text]
     
  464. pH-sensitive liposomes are efficient carriers for endoplasmic reticulum-targeted drugs in mouse melanoma cells.
    G.E. Costin, M. Trif, N. Nichita, R.A. Dwek and S.M. Petrescu (2002) Biochem. Biophys. Res. Commun., 293, 918-923. [Full text]
     
  465. Comparison of the N-linked glycans from soluble and GPI-anchored CD59 expressed in CHO cells.
    S.F. Wheeler, P.M. Rudd, S.J. Davis, R.A. Dwek and D.J. Harvey (2002) Glycobiology, 12 261-271. [Full text]
     
  466. Orientation of bound ligands in mannose-binding proteins - Implications for multivalent ligand recognition.
    K.K.S. Ng, A.R. Kolatkar, S. Park-Snyder, H. Feinberg, D.A. Clark, K. Drickamer and W.I. Weis (2002) J. Biol. Chem., 277, 16088-16095. [Full text]
     
  467. An endogenous Drosophila receptor for glycans bearing 1,3-linked core fucose residues.
    S. Bouyain, N.J. Silk, G. Fabini and K. Drickamer (2002) J. Biol. Chem., 277, 22566-22572. [Full text]
     
  468. Inhibition of host ER glucosidase activity prevents Golgi processing of virion-associated bovine viral diarrhea virus E2 glycoproteins and reduces infectivity of secreted virions.
    R. Jordan, O.V. Nikolaeva, L.J. Wang, B. Conyers, A. Mehta, R.A. Dwek and T.M. Block (2002) Virology, 295, 10-19. [Full text]
     
  469. Preparation, biochemical characterization and biological properties of radiolabelled N-alkylated deoxynojirimycins.
    H.R. Mellor, J. Nolan, L. Pickering, M.R. Wormald, F.M. Platt, R.A. Dwek, G.W.J. Fleet and T.D. Butters (2002) Biochem. J., 366, p225-233. [Full text]
     
  470. Contrasting IgG structures reveal extreme asymmetry and flexibility.
    E.O. Saphire, R.L. Stanfield, M.D.M. Crispin, P.W.H.I. Parren, P.M. Rudd, R.A. Dwek, D.R. Burton and I.A. Wilson (2002) J. Mol. Biol., 319, 9-18. [Full text]
     
  471. A molecular basis of the therapeutic and psychoactive properties of cannabis (D9-tetrahydrocannabinol).
    G. Nahas, D.J. Harvey, K. Sutin, H. Turndorf and R. Cancro (2002) Progress in Neuro-Psychopharmacy and Biological Psychiatry, 26, 721-730. [Full text]
     
  472. Editorial overview - Hot roles for glycosylation : signal transduction, control of cell development and differentiation, and innate immunity.
    M.R. Wormald and N. Sharon (2002) Curr. Op. Struc. Biol., 12, 567-568. [Full text]
     
  473. Glycosylation and prion protein.
    P.M. Rudd, A.H. Merry, M.R. Wormald and R.A. Dwek (2002) Curr. Op. Struc. Biol., 12, 578-586. [Full text]
     
  474. Role of disulfide bond formation in the folding and assembly of the envelope glycoproteins of a pestivirus.
    N. Branza-Nichita, C. Lazar, D. Durantel, R.A. Dwek and N. Zitzmann (2002) Biochem. Biophys. Res. Commun., 296, 470-476. [Full text]
     
  475. Structural and functional aspects of complement activation by mannose-binding protein.
    R. Wallis (2002) Immunobiology, 205, 433-445. [Full text]
     
  476. An inducible mouse model of late onset Tay-Sachs disease.
    M. Jeyakumar, D. Smith, E. Eliott-Smith, M. Cortina-Borja, G. Reinkensmeier, T.D. Butters, T. Lemm, K. Sandhoff, V.H. Perry, R.A. Dwek and F.M. Platt (2002) Neurobiology of Disease, 10, 201-210. [Full text]
     
  477. Glycosphingolipid lysosomal storage diseases: therapy and pathogenesis.
    M. Jeyakumar, T.D. Butters, R.A. Dwek and F.M. Platt (2002) Neuropathology and Applied Neurobiology, 28, 343-357. [Full text]
     
  478. Total synthesis of the Glc3Man N-glycan tetrasaccharide.
    S.C. Ennis, I. Cumpstey, A.J. Fairbanks, T.D. Butters, M. Mackeen and M.R. Wormald (2002) Tetrahedron, 58, 9403-9411. [Full text]
     
  479. Minireview - Glycan arrays for functional genomics.
    K. Drickamer and M.E. Taylor (2002) Genome Biology, 3, 1034.1-1034.4. [Full text]
     
  480. Monitoring endoplasmic reticulum-to-golgi traffic of a plant calreticulin by protein glycosylation analysis.
    L. Navazio, M. Miuzzo, L. Royle, B. Baldan, S. Varotto, A.H. Merry, D.J. Harvey, R.A. Dwek, P.M. Rudd and P. Mariani (2002) Biochemistry, 41, 14141-14149. [Full text]
     
  481. The combination of interferon alpha-2b and N-butyl deoxynojirimycin has a greater than additive antiviral effect upon production of infectious bovine viral diarrhea virus (BVDV) in vitro: implications for hepatitis C virus (HCV) therapy.
    S. Ouzounov, A. Mehta, R.A. Dwek, T.M. Block and R. Jordan (2002) Antiviral Res., 55, 425-435. [Full text]
     
  482. Structure-activity relationship of a new class of anti-hepatitis B virus agents.
    A. Mehta, B. Conyers, D.L.J. Tyrrell, K.A. Walters, G.A. Tipples, R.A. Dwek and T.M. Block (2002) Antimicrobial Agents and Chemotherapy, 46, 4004-4008. [Full text]
     
  483. Glucosylceramide modulates membrane traffic along the endocytic pathway.
    D.J. Sillence, V. Puri, D.L. Marks, T.D. Butters, R.A. Dwek, R.E. Pagano and F.M. Platt (2002) J. Lipid Res., 43, 1837-1845. [Full text]
     
  484. Identification of specific glycoforms of major histocompatibility complex class I heavy chains suggests that class I peptide loading is an adaptation of the quality control pathway involving calreticulin and ERp57.
    C.M. Radcliffe, G. Diedrich, D.J. Harvey, R.A. Dwek, P. Cresswell and P.M. Rudd (2002) J. Biol. Chem., 277, 46415-46423. [Full text]
     
  485. Genomic analysis of C-type lectins.
    K. Drickamer and A.J. Fadden (2002) Biochem. Soc. Symp., 69, 59-72. [Full text]
     
  486. Reversible infertility in male mice after oral administration of alkylated imino sugars: A nonhormonal approach to male contraception.
    A.C. van der Spoel, M. Jeyakumar, T.D. Butters, H.M. Charlton, H.D. Moore, R.A. Dwek and F.M. Platt (2002) Proc. Natl. Acad. Sci. USA, 99, 17173-17178. [Full text]
     
  487. Characterization of sugar binding by the mannose receptor family member, Endo180.
    L. East, S. Rushton, M.E. Taylor and C.M. Isacke (2002) J. Biol. Chem., 277, 50469-50475. [Full text]
     
  488. Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9).
    P.E. Van den Steen, B. Dubois, I. Nelissen, P.M. Rudd, R.A. Dwek and G. Opdenakker (2002) Crit. Rev. Biochem. Mol. Biol., 37, 375-536. [Full text]
     
  489. Control in the N-linked glycoprotein biosynthesis pathway.
    T.D. Butters (2002) Chemistry and Biology, 9, 1266-1268. [Full text]
     
  490. Deregulation of membrane and receptor mediated signalling by THC - therapeutic implications.
    G.G. Nahas, D.J. Harvey, K.M. Sutin, H. Turndorf and R. Cancro (2002) in "Biology of Marijuana: From Genes to Behavior", pp.431-448, ed. E.S. Onaivi (Taylor and Francis, New York).
     
  491. Imino sugars that are less toxic but more potent as antivirals, in vitro, compared with N-n-nonyl DNJ.
    A. Mehta, S. Ouzounov, R. Jordan, E. Simsek, X. Lu, R.M. Moriarty, G.S. Jacob, R.A. Dwek and T.M. Block (2002) Antiviral Chemistry and Chemotherapy, 13, 299-304. [Full text]

    2003 - Top-Bottom

  492. Enzymatic preparation and isolation of glycopeptides.
    D.J. Harvey (2003) in "Protein sequencing protocols", 2nd edition, pp.83-89, ed. B.J. Smith (Humana Press, Totowa, NJ).
     
  493. Identification of sites of glycosylation.
    D.J. Harvey (2003) in "Protein sequencing protocols", 2nd edition, pp.371-383, ed. B.J. Smith (Humana Press, Totowa, NJ).
     
  494. Australine and related alkaloids: easy structural confirmation by C-13 NMR spectral data and biological activities.
    A. Kato, E. Kano, I. Adachi, R.J. Molyneux, A.A. Watson, R.J. Nash, G.W.J. Fleet, M.R. Wormald, H. Kizu, K. Ikeda and N. Asano (2003) Tetrahedron: Asymmetry, 14, 325-331. [Full text]
     
  495. Matrix-assisted laser desorption/ionization mass spectrometry of carbohydrates and glycoconjugates.
    D.J. Harvey (2003) Int. J. Mass Spectrom., 226, 1-35. [Full text]
     
  496. Central nervous system inflammation is a hallmark of pathogenesis in mouse models of GM1 and GM2 gangliosidosis.
    M. Jeyakumar, R. Thomas, E. Elliot-Smith, D.A. Smith, A.C. van der Spoel, A. d’Azzo, V.H. Perry, T.D. Butters, R.A. Dwek and F.M. Platt (2003) Brain, 126, 974-987. [Full text]
     
  497. The hepatitis C virus p7 protein forms an ion channel that is inhibited by long-alkyl-chain iminosugar derivatives.
    D. Pavlovic, D.C.A. Neville, O. Argaud, B.S. Blumberg, R.A. Dwek, W.B. Fischer and N. Zitzmann (2003) Proc. Natl. Acad. Sci. USA, 100, 6104-6108. [Full text]
     
  498. Structural determination of the N-glycans of a lepidopteran arylphorin reveals the presence of a monoglucosylated oligosaccharide in the storage protein.
    S. Kim, S.K. Hwang, R.A. Dwek, P.M. Rudd, Y.H. Ahn, E.H. Kim, C. Cheong, S.I. Kim, N.S. Parks and S.M. Lees (2003) Glycobiology, 13, 147-157. [Full text]
     
  499. Characterization of carbohydrate recognition by langerin, a C-type lectin of Langerhans cells.
    N.S. Stambach and M.E. Taylor (2003) Glycobiology, 13, 401-410. [Full text]
     
  500. Therapeutic applications of imino sugars in lysosomal storage disorders.
    T.D. Butters, R.A. Dwek and F.M. Platt (2003) Curr. Top. Med. Chem., 3, 561-574. [Full text]
     
  501. A strategy for the comparative analysis of serum proteomes for the discovery of biomarkers for hepatocellular carcinoma.
    L.F. Steel, D. Shumpert, M. Trotter, S.H. Seeholzer, A.A. Evans, W.T. London, R.A. Dwek and T.M. Block (2003) Proteomics, 3, 601-609. [Full text]
     
  502. Glycosylation of human pancreatic ribonuclease: differences between normal and tumor states.
    R. Peracaula, L. Royle, G. Tabarés, G. Mallorquí-Fernández, S. Barrabés, D.J. Harvey, R.A. Dwek, P.M. Rudd and R. de Llorens (2003) Glycobiology, 13, 227-244. [Full text]
     
  503. Altered glycosylation pattern allows the distinction between prostate-specific antigen (PSA) from normal and tumor origins.
    R. Peracaula, G. Tabares, L. Royle, D.J. Harvey, R.A. Dwek, P.M. Rudd and R. de Llorens (2003) Glycobiology, 13, 457-470. [Full text]
     
  504. Introduction - Glycolipids in cell biology and medicine.
    R.A. Dwek, T.D. Butters, F.M. Platt and T.M. Cox (2003) Phil. Trans. Roy. Soc. B, 358, 845-846. [Full text]
     
  505. Small-molecule therapeutics for the treatment of glycolipid lysosomal storage disorders.
    T.D. Butters, H.R. Mellor, K. Narita, R.A. Dwek and F.M. Platt (2003) Phil. Trans. Roy. Soc. B, 358, 927-945. [Full text]
     
  506. Substrate reduction therapy in mouse models of the glycosphingolipidoses.
    F.M. Platt, M. Jeyakumar, U. Andersson, T. Heare, R.A. Dwek and T.D. Butters (2003) Phil. Trans. Roy. Soc. B, 358, 947-954. [Full text]
     
  507. Crystal structure of the CUB1-EGF-CUB2 region of mannose-binding protein associated serine protease-2.
    H. Feinberg, J.C.M. Uitdehaag, J.M. Davies, R. Wallis, K. Drickamer and W.I. Weis (2003) EMBO J., 22, 2348-235. [Full text]
     
  508. Secretory IgA N- and O-glycans provide a link between the innate and adaptive immune systems.
    L. Royle, A. Roos, D.J. Harvey, M.R. Wormald, D.J. van Gijlswijk-Janssen, E.R.M. Redwan, I.A. Wilson, M.R. Daha, R.A. Dwek and P.M. Rudd (2003) J. Biol. Chem., 278, 20140-20153. [Full text]
     
  509. Antibody domain exchange is an immunological solution to carbohydrate cluster recognition.
    D.A. Calarese, C.N. Scanlan, M.B. Zwick, S. Deechongkit, Y. Mimura, R. Kunert, P. Zhu, M.R. Wormald, R.L. Stanfield, K.H. Roux, J.W. Kelly, P.M. Rudd, R.A. Dwek, H. Katinger, D.R. Burton and I.A. Wilson (2003) Science, 300, 2065-2071. [Full text]
     
  510. Function and glycosylation of plant-derived antiviral monoclonal antibody.
    K. Ko, Y. Tekoah, P.M. Rudd, D.J. Harvey, R.A. Dwek, S. Spitsin, C.A. Hanlon, C. Rupprecht, B. Dietzschold, M. Golovkin and H. Koprowski (2003) Proc. Natl. Acad. Sci. USA, 100, 8013-8018. [Full text]
     
  511. Oligolysine-based oligosaccharide clusters: selective recognition and endocytosis by the mannose receptor and DC-SIGN.
    S. Frison, M.E. Taylor, E. Soilleux, M.T. Bousser, R. Mayer, M. Monsigny, K. Drickamer and A.C. Roche (2003) J. Biol. Chem. 278, 23922-23929. [Full text]
     
  512. Reversed-phase ion pairing HPLC coupled to ion trap MS for the analysis of negatively charged ANTS derivatised glycans.
    L.A. Gennaro, D.J. Harvey and P. Vouros (2003) Rapid Commun. Mass Spectrom., 17, 1528-1534. [Full text]
     
  513. Storage diseases: new insights into sphingolipid functions.
    D.J. Sillence and F.M. Platt (2003) Trends in Cell Biology, 13, 195-203. [Full text]
     
  514. Letter - Plastic surgery beyond the human genome.
    J. Pleat, C. Dunkin and N. Zitzmann (2003) Plastic and Reconstructive Surgery, 111, 2479-2480. [Full text]
     
  515. The inhibition of early N-glycan processing targets TRP-2 to degradation in B16 melanoma cells.
    G. Negroiu, R.A. Dwek and S.M. Petrescu (2003) J. Biol. Chem., 278, 27035-27042. [Full text]
     
  516. O-glycan sialylation and the structure of the stalk-like region of the T cell coreceptor CD8.
    A.H. Merry, R.J.C. Gilbert, D.A. Shore, L. Royle, O. Miroshnychenko, M. Vuong, M.R. Wormald, D.J. Harvey, R.A. Dwek, B.J. Classon, P.M. Rudd and S.J. Davis (2003) J. Biol. Chem., 278, 27119-27128. [Full text]
     
  517. Inhibition of calcium uptake via the sarco/endoplasmic reticulum Ca2+-ATPase in a mouse model of Sandhoff disease and prevention by treatment with N-butyldeoxynojirimycin.
    D. Pelled, E. Lloyd-Evans, C. Riebeling, M. Jeyakumar, F.M. Platt and A.H. Futerman (2003) J. Biol. Chem., 278, 29496-29501. [Full text]
     
  518. Molecular characterization of the rat Kupffer cell glycoprotein receptor.
    A.J. Fadden, O.J. Holt and K. Drickamer (2003) Glycobiology, 13, 529-537. [Full text]
     
  519. Synthesis of fluorescence-labelled disaccharide substrates of glucosidase II.
    I. Cumpstey, T.D. Butters, R.J. Tennant-Eyles, A.J. Fairbanks, R.R. France and M.R. Wormald (2003) Carbohydr. Res., 338, 1937-1949. [Full text]
     
  520. Detailed glycan analysis of serum glycoproteins of patients with congenital disorders of glycosylation indicates the specific defective glycan processing step and provides an insight into pathogenesis.
    M. Butler, D. Quelhas, A.J. Critchley, H. Carchon, H.F. Hebestreit, R.G. Hibbert, L. Vilarinho, E. Teles, G. Matthijs, E. Schollen, P. Argibay, D.J. Harvey, R.A. Dwek, J. Jaeken and P.M. Rudd (2003) Glycobiology, 13, 601-622. [Full text]
     
  521. Membrane disruption and cytotoxicity of hydrophobic N-alkylated imino sugars is independent of the inhibition of protein and lipid glycosylation.
    H.R. Mellor, F.M. Platt, R.A. Dwek and T.D. Butters (2003) Biochem. J., 374, 307-314. [Full text]
     
  522. Identification of lectins from genomic sequence data.
    K. Drickamer and M.E. Taylor (2003) in "Recognition of Carbohydrates in Biological Systems, Part A : General Procedures", Methods in Enzymology, 362, pp.560-567, ed. Y. Lee and R. Lee (Academic Press Inc, San Diego). [Full text]
     
  523. Structure-function analysis of C-type animal lectins.
    M.E. Taylor and K. Drickamer (2003) in "Recognition of Carbohydrates in Biological Systems, Part B : Specific Applications", Methods in Enzymology, 363, pp.3-16, ed. Y. Lee and R. Lee (Academic Press Inc, San Diego). [Full text]
     
  524. The pestivirus E-rns glycoprotein interacts with E2 in both infected cells and mature virions.
    C. Lazar, N. Zitzmann, R.A. Dwek and N. Branza-Nichita (2003) Virology, 314, 696-705. [Full text]
     
  525. Crystal structure of an intact human IgG: Antibody asymmetry, flexibility, and a guide for HIV-1 vaccine design.
    E.O. Saphire, R.L. Stanfield, M.D.M. Crispin, G. Morris, M.B. Zwick, R.A. Pantophlet, P.W.H.I. Parren, P.M. Rudd, R.A. Dwek, D.R. Burton and I.A. Wilson (2003) Adv. Exp. Med. Biol., 535, 55-66.
     
  526. The carbohydrate epitope of the neutralizing anti-HIV-1 antibody 2G12.
    C.N. Scanlan, R.A. Pantophlet, M.R. Wormald, E.O. Saphire, D. Calarese, R.L. Stanfield, I.A. Wilson, H. Katinger, R.A. Dwek, D.R. Burton and P.M. Rudd (2003) Adv. Exp. Med. Biol., 535, 205-218. [Full text]
     
  527. New therapeutics for the treatment of glycosphingolipid lysosomal storage diseases.
    T.D. Butters, R.A. Dwek and F.M. Platt (2003) Adv. Exp. Med. Biol., 535, 219-226.
     
  528. The glycosylation of tyrosinase in melanoma cells and the effect on antigen presentation.
    S.M. Petrescu, C.I. Popescu, A.J. Petrescu and R.A. Dwek (2003) Adv. Exp. Med. Biol., 535, 257-269.
     
  529. Structural basis for mannose-binding protein function in innate immunity.
    R. Wallis (2003) in "Immunobiology of Carbohydrates", pp.34-45, ed. S.Y.C. Wong and G. Arsequell (Kluwer Academic). [Full text]
     
  530. Glycolipid depletion in antimicrobial therapy.
    M. Svensson, B. Frendeus, T.D. Butters, F.M. Platt, R.A. Dwek and C. Svanborg (2003) Mol. Microbiol., 47, 453-461. [Full text]

    2004 - Top-Bottom

  531. Statistical analysis of the protein environment of N-glycosylation sites: implications for occupancy, structure and folding.
    A.J. Petrescu, A.L. Milac, S.M. Petrescu, R.A. Dwek and M.R. Wormald (2004) Glycobiology, 14, 103-114. [Full text]
     
  532. Inhibition of glycogen breakdown by imino sugars in vitro and in vivo.
    U. Andersson, G. Reinkensmeier, T.D. Butters, R.A. Dwek and F.M. Platt (2004) Biochem. Pharmacology, 67, 697-705. [Full text]
     
  533. Complement regulation at the molecular level: the structure of decay-accelerating factor.
    P. Lukacik, P. Roversi, J. White, D. Esser, G.P. Smith, J. Billington, P.A. Williams, P.M. Rudd, M.R. Wormald, D.J. Harvey, M.D.M. Crispin, C.M. Radcliffe, R.A. Dwek, D.J. Evans, B.P. Morgan, R.A.G. Smith and S.M. Lea (2004) Proc. Natl. Acad. Sci. USA, 101, 1279-1284. [Full text]
     
  534. Effects of interferon, ribavirin, and iminosugar derivatives on cells persistently infected with noncytopathic bovine viral diarrhea virus.
    D. Durantel, S. Carrouée-Durantel, N. Branza-Nichita, R.A. Dwek and N. Zitzmann (2004) Antimicrobial Agents and Chemotherapy, 48, 497-504. [Full text]
     
  535. Lysosomal defects and storage.
    F.M. Platt and S.U. Walkley (2004) in "Lysosomal Disorders of the Brain", pp.32-49, ed. F.M. Platt and S.U. Walkley (Oxford University Press).
     
  536. Inhibition of substrate synthesis: a pharmacological approach for glycosphingolipid storage disease therapy.
    F.M. Platt and T.D. Butters (2004) in "Lysosomal Disorders of the Brain", pp.381-408, ed. F.M. Platt and S.U. Walkley (Oxford University Press).
     
  537. Localization of the serine protease-binding sites in the collagen-like domain of mannose-binding protein: indirect effects of naturally occuring mutations on protease binding and activation.
    R. Wallis, J.M. Shaw, J. Uitdehaag, C.B. Chen, D. Torgersen and K. Drickamer (2004) J. Biol. Chem., 279, 14065-14073. [Full text]
     
  538. Structure, dynamics and interactions of p47, a major adaptor of the AAA ATPase, p97.
    X. Yuan, P. Simpson, C. McKeown, H. Kondo, K. Uchiyama, R. Wallis, I. Dreveny, C. Keetch, X. Zhang, C. Robinson, P. Freemont and S. Matthews (2004) EMBO J., 23, 1463-1473. [Full text]
     
  539. Extensive analysis of the human platelet proteome by two-dimensional gel electrophoresis and mass spectrometry.
    A. Garcia, S. Prabhakar, C.J. Brock, A.C. Pearce, R.A. Dwek, S.P. Watson, H.F. Hebestreit and N. Zitzmann (2004) Proteomics, 4, 656-668. [Full text]
     
  540. Differential proteome analysis of TRAP-activated platelets: involvement of DOK-2 and phosphorylation of RGS proteins.
    A. Garcia, S. Prabhakar, S. Hughan, T.W. Anderson, C.J. Brock, A.C. Pearce, R.A. Dwek, S.P. Watson, H.F. Hebestreit and N. Zitzmann (2004) Blood, 103, 2088-2095. [Full text]
     
  541. Reactivity-based one-pot synthesis of oligomannoses: Defining antigens recognized by 2G12, a broadly neutralizing anti-HIV-1 antibody.
    H.K. Lee, C.N. Scanlan, C.Y. Huang, A.Y. Chang, D.A. Calarese, R.A. Dwek, P.M. Rudd, D.R. Burton, I.A. Wilson and C.H. Wong (2004) Angew. Chem. Int. Ed., 43, 1000-1003. [Full text]
     
  542. Maternally expressed gene1 is a novel maize endosperm transfer cell-specific gene with a maternal parent-of-origin pattern of expression.
    J.F. Gutierrez-Marcos, L.M. Costa, C. Biderre-Petit, B. Khbaya, D. O'Sullivan, M.R. Wormald, P. Perez and H.G. Dickinson (2004) Plant Cell, 16, p.1288-1301. [Full text]
     
  543. N-butyldeoxygalactonojirimycin reduces neonatal brain ganglioside content in a mouse model of GM1 gangliosidosis.
    J.L. Kasperzyk, M.M. El-Abbadi, E.C. Hauser, A. d'Azzo, F.M. Platt and T.N. Seyfried (2004) J. Neurochem., 89, 645-653. [Full text]
     
  544. Controlled glycosylation of therapeutic antibodies in plants.
    Y. Tekoah, K. Ko, H. Koprowski, D.J. Harvey, M.R. Wormald, R.A. Dwek and P.M. Rudd (2004) Archives of Biochemistry and Biophysics, 426, 266-278. [Full text]
     
  545. Monoglucosylated glycans in the secreted human complement component C3: implications for protein biosynthesis and structure.
    M.D.M. Crispin, G.E. Ritchie, A.J. Critchley, B.P. Morgan, I.A. Wilson, R.A. Dwek, R.B. Sim and P.M. Rudd (2004) FEBS Letters, 566, 270-274. [Full text]
     
  546. Two mechanisms for mannose-binding protein modulation of the activity of its associated serine proteases.
    C.B. Chen and R. Wallis (2004) J. Biol. Chem., 279, 26058-26065. [Full text]
     
  547. Major histocompatibility complex class I molecules expressed with monoglucosylated N-linked glycans bind calreticulin independently of their assembly status.
    P.A. Wearsch, C.A. Jakob, A. Vallin, R.A. Dwek, P.M. Rudd and P. Cresswell (2004) J. Biol. Chem., 279, 25112-25121. [Full text]
     
  548. Accumulation of glycosphingolipids in Niemann-Pick C disease disrupts endosomal transport.
    D.T. Vruchte, E. Lloyd-Evans, R.J. Veldman, D.C.A. Neville, R.A. Dwek, F.M. Platt, W.J. van Blitterswijk and D.J. Sillence (2004) J. Biol. Chem., 279, 26167-26175. [Full text]
     
  549. alpha-galactosylceramide and novel synthetic glycolipids directly induce the innate host defense pathway and have direct activity against hepatitis B and C viruses.
    A.S. Mehta, B.H. Gu, B. Conyers, S. Ouzounov, L.J. Wang, R.M. Moriarty, R.A. Dwek and T.M. Block (2004) Antimicrobial Agents and Chemotherapy, 48, 2085-2090. [Full text]
     
  550. Role of N-glycan trimming in the folding and secretion of the pestivirus protein E-rns.
    N. Branza-Nichita, C. Lazar, R.A. Dwek and N. Zitzmann (2004) Biochem. Biophys. Res. Commun., 319, 655-662. [Full text]
     
  551. Phylogenetic analysis of the vertebrate galectin family.
    D. Houzelstein, I.R. Goncalves, A.J. Fadden, S.S. Sidhu, D.N.W. Cooper, K. Drickamer, H. Leffler and F. Poirier (2004) Molecular Biology and Evolution, 21, 1177-1187. [Full text]
     
  552. Structural basis for distinct ligand-binding and targeting properties of the receptors DC-SIGN and DC-SIGNR.
    Y. Guo, H. Feinberg, E. Conroy, D.A. Mitchell, R. Alvarez, O. Blixt, M.E. Taylor, W.I. Weis and K. Drickamer (2004) Nat. Struct. Mol. Biol., 11, 591-598. [Full text]
     
  553. Editorial - Introduction: glycosphingolipids in cell biology and disease
    D.J. Sillence and F.M. Platt (2004) Semin. Cell Dev. Biol., 15, 371-373. [Full text]
     
  554. Glycosphingolipids in endocytic membrane transport
    D.J. Sillence and F.M. Platt (2004) Semin. Cell Dev. Biol., 15, 409-416. [Full text]
     
  555. Analysis of fluorescently labeled glycosphingolipid-derived oligosaccharides following ceramide glycanase digestion and anthranilic acid labeling.
    D.C.A. Neville, V. Coquard, D.A. Priestman, D.J.M. te Vruchte, D.J. Sillence, R.A. Dwek, F.M. Platt and T.D. Butters (2004) Anal. Biochem., 331, 275-282. [Full text]
     
  556. Improved outcome of N-butyldeoxygalactonojirimycin-mediated substrate reduction therapy in a mouse model of Sandhoff disease.
    U. Andersson, D. Smith, M. Jeyakumar, T.D. Butters, M. Cortina-Borja, R.A. Dwek and F.M. Platt (2004) Neurobiology of Disease, 16, 506-515. [Full text]
     
  557. Treatment with miglustat reverses the lipid-trafficking defect in Niemann-Pick disease type C.
    R.H. Lachmann, D.J.M. te Vruchte, E. Lloyd-Evans, G. Reinkensmeier, D.J. Sillence, L. Fernandez-Guillen, R.A. Dwek, T.D. Butters, T.M. Cox and F.M. Platt (2004) Neurobiology of Disease, 16, 654-658. [Full text]
     
  558. Differential effects of alpha-subunit asparagine 56 oligosaccharide structure on equine lutropin and follitropin hybrid conformation and receptor-binding activity.
    G.R. Bousfield, V.Y. Butnev, V.Y. Butnev, V.T. Nguyen, C.M. Gray, J.A. Dias, R. MacColl, L. Eisel and D.J. Harvey (2004) Biochemistry, 43, 10817-10833. [Full text]
     
  559. Looking glass inhibitors: L-DMDP, a more potent and inhibitor of a-glucosidases than the enantiomeric natural product DMDP.
    C.Y. Yu, N. Asano, K. Ikeda, M.X. Wang, T.D. Butters, M.R. Wormald, R.A. Dwek, A.L. Winters, R.J. Nash and G.W.J. Fleet (2004) Chem. Commun., 17, 1936-1937. [Full text]
     
  560. The mannose receptor fails to enhance processing and presentation of a glycoprotein antigen in transfected fibroblasts.
    C.E. Napper and M.E. Taylor (2004) Glycobiology, 14, 7C-12C. [Full text]
     
  561. Letter - Artefacts formed by addition of urea to N-linked glycans released with peptide-N-glycosidase F for analysis by mass spectrometry.
    L.A. Omtvedt, L. Royle, G. Husby, K. Sletten, C.M. Radcliffe, D.J. Harvey, R.A. Dwek and P.M. Rudd (2004) Rapid Commun. Mass Spectrom., 18, 2357-2359. [Full text]
     
  562. Sugar-mediated ligand-receptor interactions in the immune system.
    P.M. Rudd, M.R. Wormald and R.A. Dwek (2004) Trends in Biotechnology, 22, 524-530. [Full text]
     
  563. Inhibition of alpha-glucosidases I and II increases the cell surface expression of functional class a macrophage scavenger receptor (SR-A) by extending its half-life.
    G. Tian, D. Wilcockson, V.H. Perry, P.M. Rudd, R.A. Dwek, F.M. Platt and N. Platt (2004) J. Biol. Chem., 279, 39303-39309. [Full text]
     
  564. Inhibition of glucosylceramide synthase does not reverse drug resistance in cancer cells.
    E. Norris-Cervetto, R. Callaghan, F.M. Platt, R.A. Dwek and T.D. Butters (2004) J. Biol. Chem., 279, 40412-40418. [Full text]
     
  565. Characterization of the oligosaccharide component of microsomal beta-glucuronidase from rat liver.
    D. Hoja-Lukowicz, T.D. Butters and A. Litynska (2004) Biochimie, 86, 363-372. [Full text]
     
  566. Cellular effects of deoxynojirimycin analogues: uptake, retention and inhibition of glycosphingolipid biosynthesis.
    H.R. Mellor, D.C.A. Neville, D.J. Harvey, F.M. Platt, R.A. Dwek and T.D. Butters (2004) Biochem. J., 381, 861-866. [Full text]
     
  567. Cellular effects of deoxynojirimycin analogues: inhibition of N-linked oligosaccharide processing and generation of free glucosylated oligosaccharides.
    H.R. Mellor, D.C.A. Neville, D.J. Harvey, F.M. Platt, R.A. Dwek and T.D. Butters (2004) Biochem. J., 381, 867-875. [Full text]
     
  568. Structural characterization of the N-glycan moiety and site of glycosylation in vitellogenin from the decapod crustacean Cherax quadricarinatus.
    I. Khalaila, J. Peter-Katalinic, C. Tsang, C.M. Radcliffe, E.D. Aflalo, D.J. Harvey, R.A. Dwek, P.M. Rudd and A. Sagi (2004) Glycobiology, 14, 767-774. [Full text]
     
  569. Editorial Overview - Progress in non-mammalian glycosylation, glycosyltransferases, invertebrate lectins and carbohydrate-carbohydrate interactions.
    M.R. Wormald and N. Sharon (2004) Curr. Op. Struc. Biol., 14, 591-592. [Full text]
     
  570. Infantile-onset symptomatic epilepsy syndrome caused by a homozygous loss-of-function mutation of GM3 synthase.
    M.A. Simpson, H. Cross, C. Proukakis, D.A. Priestman, D.C.A. Neville, G. Reinkensmeier, H. Wang, M. Wiznitzer, K. Gurtz, A. Verganelaki, A. Pryde, M.A. Patton, R.A. Dwek, T.D. Butters, F.M. Platt and A.H. Crosby (2004) Nature Genetics, 36, 1225-1229. [Full text]
     
  571. Analyzing the platelet proteome.
    A. Garcia, N. Zitzmann and S.P. Watson (2004) Semin. Thromb. Hemost., 30, 485-489. [Full text]
     
  572. NSAIDs increase survival in the Sandhoff disease mouse: Synergy with N-butyldeoxynojirimycin.
    M. Jeyakumar, D.A. Smith, I.M. Williams, M. Cortina-Borja, D.C.A. Neville, T.D. Butters, R.A. Dwek and F.M. Platt (2004) Annals of Neurology, 56, 642-649. [Full text] [Correction]
     
  573. Therapy of Niemann-Pick disease, type C.
    M.C. Patterson and F.M. Platt (2004) Biochim. Biophys. Acta, 1685, 77-82. [Full text]
     
  574. Sustained therapeutic effects of oral miglustat (Zavesca, N-butyldeoxynojirimycin, OGT 918) in type I Gaucher disease.
    D. Elstein, C. Hollak, J.M.F.G. Aerts, S. van Weely, M. Maas, T.M. Cox, R.H. Lachmann, M. Hrebicek, F.M. Platt, T.D. Butters, R.A. Dwek and A. Zimran (2004) J. Inherit. Metab. Dis., 27, 757-766. [Full text]
     
  575. A statistical comparison of silver and SYPRO Ruby staining for proteomic analysis.
    I.R. White, R. Pickford, J. Wood, J.M. Skehel, B. Gangadharan and P. Cutler (2004) Electrophoresis, 25,3048-3054. [Full text]
     
  576. Abnormal cell cycle regulation in primary human uveal melanoma cultures.
    M. Pardo, A. Pineiro, M. de la Fuente, A. Garcia, S. Prabhakar, N. Zitzmann, R.A. Dwek, M. Sanchez-Salorio, F. Dominguez and C. Capeans (2004) J. Cell. Biochem., 93, 708-720. [Full text]
     
  577. Global analysis of predicted proteomes: functional adaptation of physical properties.
    C.G. Knight, R. Kassen, H.F. Hebestreit and P.B. Rainey (2004) Proc. Natl. Acad. Sci. U.S.A., 101, 8390-8395. [Full text]
     
  578. Fragmentation of N-linked glycans with a matrix-assisted laser desorption/ionization ion trap time-of-flight mass spectrometer.
    D.J. Harvey, R.L. Martin, K.A. Jackson and C.W. Sutton (2004) Rapid Commun. Mass Spectrom., 18, 2997-3007. [Full text]
     
  579. The glycosylation of human serum IgD and IgE and the accessibility of identified oligomannose structures for interaction with mannan binding lectin.
    J.N. Arnold, C.M. Radcliffe, M.R. Wormald, L. Royle, D.J. Harvey, M.D.M. Crispin, R.A. Dwek, R.B. Sim and P.M. Rudd (2004) J. Immunol., 173, 6831-6840. [Full text]
     
  580. Identification and removal of O-linked and non-covalently linked sugars from recombinant protein produced using Pichia pastoris.
    J.M. O'Leary, C.M. Radcliffe, A.C. Willis, R.A. Dwek, P.M. Rudd and A.K. Downing (2004) Protein Expression and Purification, 38, 217-227. [Full text]
     
  581. Rôle de la glycosylation des protéines d'enveloppe dans la morphogenčse des Flaviviridae et son inhibition par.
    C. Chapel, I. Vuillermoz, N. Zitzmann, C. Trépo, F. Zoulim and D. Durantel (2004) Virologie, 8, 95-111. [Full text]

    2005 - Top-Bottom

  582. Chromatography: Mass spectrometry.
    D.J. Harvey (2005) in "Encyclopedia of Analytical Science", 2nd edition, vol. 4, pp.106-115, ed. P.J. Worsfold, A. Townshend and C. Poole (Elsevier, Oxford).
     
  583. Mass spectrometry: Ionization methods overview.
    D.J. Harvey (2005) in "Encyclopedia of Analytical Science", 2nd edition, vol. 5, pp.350-358, ed. P.J. Worsfold, A. Townshend and C. Poole (Elsevier, Oxford).
     
  584. Mass spectrometry: Matrix-assisted laser desorption/ionization.
    D.J. Harvey (2005) in "Encyclopedia of Analytical Science", 2nd edition, vol. 5, pp.386-396, ed. P.J. Worsfold, A. Townshend and C. Poole (Elsevier, Oxford).
     
  585. Alkali metals and carbohydrates.
    D.J. Harvey (2005) in "Encyclopedia of Mass Spectrometry", vol. 4, pp. 584-592 (Elsevier, Amsterdam).
     
  586. Letter - Differentiation between sulphated and phosphated carbohydrates in low resolution MALDI mass spectra.
    D.J. Harvey and G.R. Bousfield (2005) Rapid Commun. Mass Spectrom., 19, 287-288. [Full text]
     
  587. Halogeno-substituted 2-aminobenzoic acid derivatives for negative ion fragmentation studies of N-linked carbohydrates.
    D.J. Harvey (2005) Rapid Commun. Mass Spectrom., 19, 397-400. [Full text]
     
  588. Ionization and fragmentation of N-linked glycans as silver adducts by electrospray mass spectrometry.
    D.J. Harvey (2005) Rapid Commun. Mass Spectrom., 19, 484-492. [Full text]
     
  589. A new charge-associated mechanism to account for the production of fragment ions in the high-energy CID spectra of fatty acids.
    D.J. Harvey (2005) J. Am. Soc. Mass Spectrom., 16, 280-290. [Full text]
     
  590. Proteomic analysis of glycosylation: Structural determination of N- and O-linked glycans by mass spectrometry.
    D.J. Harvey (2005) Expert Rev. Proteomics, 2, 87-101. [Full text]
     
  591. Extended neck regions stabilize tetramers of the receptors DC-SIGN and DC-SIGNR.
    H. Feinberg, Y. Guo, D.A. Mitchell, K. Drickamer and W.I. Weis (2005) J. Biol. Chem., 280, 1327-1335. [Full text]
     
  592. Use of targeted glycoproteomics to identify serum glycoproteins that correlate with liver cancer in woodchucks and humans.
    T.M. Block, M.A. Comunale, M. Lowman, L.F. Steel, P.R. Romano, C. Fimmel, B.C. Tennant, W.T. London, A.A. Evans, B.S. Blumberg, R.A. Dwek, T.S. Mattu and A.S. Mehta (2005) Proc. Natl. Acad. Sci. USA, 102, 779-784. [Full text]
     
  593. Molecular mechanism of lipopeptide presentation by CD1a.
    D.M. Zajonc, M.D.M. Crispin, T.A. Bowden, D.C. Young, T.Y. Cheng, J.D. Hu, C.E. Costello, P.M. Rudd, R.A. Dwek, M.J. Miller, M.B. Brenner, D.B. Moody and I.A. Wilson (2005) Immunity, 22, 209-219. [Full text]
     
  594. Epitope recognition of antibodies that define the sialomucin, endolyn (CD164), a negative regulator of haematopoiesis.
    B. Jorgensen-Tye, J.P. Levesque, L. Royle, R. Doyonnas, J.Y.H. Chan, R.A. Dwek, P.M. Rudd, D.J. Harvey, P.J. Simmons and S.M. Watt (2005) Tissue Antigens, 65, 220-239. [Full text]
     
  595. Tyrosinase-related protein-2 and-1 are trafficked on distinct routes in B16 melanoma cells.
    G. Negroiu, R.A. Dwek and S.M. Petrescu (2005) Biochem. Biophys. Res. Commun., 328, 914-921. [Full text]
     
  596. Alkylated imino sugars, reversible male infertility-inducing agents, do not affect genetic integrity of male mouse germ cells during short-term treatment despite induction of sperm deformities.
    R. Suganuma, C.M. Walden, T.D. Butters, F.M. Platt, R.A. Dwek, R. Yanagimachi and A.C. van der Spoel (2005) Biology of Reproduction, 72, 805-813. [Full text]
     
  597. 2-Acetamido-N-benzyl-1,4-imino-1,2,4-trideoxy-L-ribitol.
    C.C. Harding, D.J. Watkin, J.S.S. Rountree, T.D. Butters, M.R. Wormald, R.A. Dwek and G.W.J. Fleet (2005), Acta Cryst., E61, o930-o932. [Full text]
     
  598. Structural determination of N-linked glycans by matrix-assisted laser desorption/ionization and electrospray ionization mass spectrometry.
    D.J. Harvey (2005) Proteomics, 5, 1774-1786. [Full text]
     
  599. Collision-induced fragmentation of negative ions from N-linked glycans derivatized with 2-aminobenzoic acid.
    D.J. Harvey (2005) J. Mass Spectrom., 40, 642-653. [Full text]
     
  600. Fragmentation of negative ions from carbohydrates: Part 1. Use of nitrate and other anionic adducts for the production of negative ion electrospray spectra from N-linked carbohydrates.
    D.J. Harvey (2005) J. Am. Soc. Mass Spectrom., 16, 622-630. [Full text]
     
  601. Fragmentation of negative ions from carbohydrates: Part 2. Fragmentation of high-mannose N-linked glycans.
    D.J. Harvey (2005) J. Am. Soc. Mass Spectrom., 16, 631-646. [Full text]
     
  602. Fragmentation of negative ions from carbohydrates: Part 3. Fragmentation of hybrid and complex N-linked glycans.
    D.J. Harvey (2005) J. Am. Soc. Mass Spectrom., 16, 647-659. [Full text]
     
  603. Design and synthesis of iminosugar-based inhibitors of glucosylceramide synthase: the search for new therapeutic agents against Gaucher disease.
    C. Boucheron, V. Desvergnes, P. Compain, O.R. Martin, A. Lavi, M. Mackeen, M.R. Wormald, R.A. Dwek and T.D. Butters (2005) Tetrahedron: Asymmetry, 16, 1747-1756. [Full text]
     
  604. 2-Acetamido-N-benzyl-1,4-imino-1,2,4-trideoxy-L-arabinitol 0.33-hydrate.
    C.C. Harding, J.S.S. Rountree, D.J. Watkin, A.R. Cowley, T.D. Butters, M.R. Wormald, R.A. Dwek and G.W.J. Fleet (2005) Acta Cryst., E61, o1683-o1685. [Full text]
     
  605. Soluble tyrosinase is an endoplasmic reticulum (ER)-associated degradation substrate retained in the ER by calreticulin and BiP/GRP78 and not calnexin.
    C.I. Popescu, C. Paduraru, R.A. Dwek and S.M. Petrescu (2005) J. Biol. Chem., 280, 13833-13840. [Full text]
     
  606. Substrate reduction reduces gangliosides in postnatal cerebrum-brainstem and cerebellum in GM1 gangliosidosis mice.
    J.L. Kasperzyk, A. d'Azzo, F.M. Platt, J. Alroy and T.N. Seyfried (2005) J. Lipid Res., 46, 744-751. [Full text]
     
  607. 1,2:3,4-Di-O-isopropylidene-a-D-tagatofuranose.
    D.J. Watkin, A.F.G. Glawar, R. Soengas, U.P. Skytte, M.R. Wormald, R.A. Dwek and G.W.J. Fleet (2005) Acta Cryst., E61, o2891-o2893. [Full text]
     
  608. Human serum IgM glycosylation: identification of glycoforms which can bind to mannan binding lectin.
    J.N. Arnold, M.R. Wormald, D.M. Suter, C.M. Radcliffe, D.J. Harvey, R.A. Dwek, P.M. Rudd and R.B. Sim (2005) J. Biol. Chem., 280, 29080-29087. [Full text]
     
  609. 1,2:3,4-Di-O-isopropylidene-b-D-psicofuranose.
    D.J. Watkin, A.F.G. Glawar, R. Soengas, K. Izumori, M.R. Wormald, R.A. Dwek and G.W.J. Fleet (2005) Acta Cryst., E61, o2949-o2951. [Full text]
     
  610. Afamin is a novel human vitamin E-binding glycoprotein: characterization and in vitro expression.
    L. Jerkovic, A.F. Voegele, S. Chwatal, F. Kronenberg, C.M. Radcliffe, M.R. Wormald, E.M. Lobentanz, B. Ezeh, P. Eller, N. Dejori, B. Dieplinger, F. Lottspeich, W. Sattler, M. Uhr, K. Mechtler, R.A. Dwek, P.M. Rudd, G. Baier and H. Dieplinger (2005) J. Proteome Res., 4, 889-899. [Full text]
     
  611. Selective binding of the scavenger receptor C-type lectin to Lewis(x) trisaccharide and related glycan ligands.
    P.J. Coombs, S.A. Graham, K. Drickamer and M.E. Taylor (2005) J. Biol. Chem., 280, 22993-22999. [Full text]
     
  612. Storage solutions: treating Lysosomal disorders of the brain.
    M. Jeyakumar, R.A. Dwek, T.D. Butters and F.M. Platt (2005) Nature Reviews Neuroscience, 6, 713-725. [Full text]
     
  613. Glycosylation influences the lectin activities of the macrophage mannose receptor.
    Y. Su, T. Bakker, J. Harris, C. Tsang, G.D. Brown, M.R. Wormald, S. Gordon, R.A. Dwek, P.M. Rudd and L. Martinez-Pomares (2005) J. Biol. Chem., 280, 32811-32820. [Full text]
     
  614. Mass Spectrometry.
    D.J. Harvey (2005) in "Encyclopedia of Genomics, Proteomics and Bioinformatics, Vol. 6", pp.2322-2331 (J. Wiley and Sons Ltd., Chichester). [Full text]
     
  615. Hepatitis B virus large and middle glycoproteins are degraded by a proteasome pathway in glucosidase-inhibited cells but not in cells with functional glucosidase enzyme.
    E. Simsek, A. Mehta, T.L. Zhou, R.A. Dwek and T. Block (2005) J. Virology, 79, 12914-12920. [Full text]
     
  616. Imino sugar inhibitors for treating the lysosomal glycosphingolipidoses.
    T.D. Butters, R.A. Dwek and F.M. Platt (2005) Glycobiology, 15, 43R-52R. [Full text]
     
  617. Applying proteomics technology to platelet research.
    A. Garcia, S.P. Watson, R.A. Dwek and N. Zitzmann (2005) Mass Spectrom. Rev., 24, 918-930. [Full text]
     
  618. Nef-mediated lipid raft exclusion of UbcH7 inhibits Cbl activity in T Cells to positively regulate signaling.
    A. Simmons, B. Gangadharan, A. Hodges, K. Sharrocks, S. Prabhakar, A. Garcia, R.A. Dwek, N. Zitzmann and A.J. McMichael (2005) Immunity, 23, 621-634. [Full text] [Supplementary data]
     
  619. Looking glass inhibitors: efficient synthesis and biological evaluation of D-deoxyfuconojirimycin.
    Y. Bleriot, D. Gretzke, T.M. Krulle, T.D. Butters, R.A. Dwek, R.J. Nash, N. Asano and G.W.J. Fleet (2005) Carbohydr. Res., 340, 2713-2718. [Full text]
     
  620. MRS reveals additional hexose N-acetyl resonances in the brain of a mouse model for Sandhoff disease.
    J.P. Lowe, D.J. Stuckey, F.R. Awan, M. Jeyakumar, D.C.A. Neville, F.M. Platt, J.L. Griffin, P. Styles, A.M. Blamire and N.R. Sibson (2005) NMR in Biomedicine, 18, 517-526. [Full text]
     
  621. Proteome analysis of a human uveal melanoma primary cell culture by 2-DE and MS.
    M. Pardo, A. Garcia, B. Thomas, A. Pineiro, A. Akoulitchev, R.A. Dwek and N. Zitzmann (2005) Proteomics, 5, 4980-4993. [Full text]
     
  622. Glycosylation: disease targets and therapy.
    N. Zitzmann, T. Block, A. Methta, P.M. Rudd, D. Burton, I.A. Wilson, F.M. Platt, T.D. Butters and R.A. Dwek (2005) Adv. Exp. Med. Biol., 564, 1-2. [Full text]
     
  623. Long alkylchain iminosugars block the HCV p7 ion channel.
    D. Pavlovic, W. Fischer, M. Hussey, D. Durantel, S. Durantel, N. Branza-Nichita, S.D. Woodhouse, R.A. Dwek and N. Zitzmann (2005) Adv. Exp. Med. Biol., 564, 3-4. [Full text]
     
  624. The bovine viral diarrhoea virus: a model for the study of antiviral molecules interfering with N-glycosylation and folding of envelope glycoprotein.
    D. Durantel, N. Branza-Nichita, S. Durantel, R.A. Dwek and N. Zitzmann (2005) Adv. Exp. Med. Biol., 564, 5-6. [Full text]
     
  625. Antibody recognition of a carbohydrate epitope: a template for HIV vaccine design.
    C.N. Scanlan, D. Calarese, H.K. Lee, O. Blixt, C.H. Wong, I.A. Wilson, D. Burton, R.A. Dwek and P.M. Rudd (2005) Adv. Exp. Med. Biol., 564, 7-8. [Full text]
     
  626. Glycosylation influences the ligand binding activities of mannose receptor.
    Y.R. Su, C. Tsang, T. Bakker, J. Harris, S. Gordon, R.A. Dwek, L. Martinez-Pomares and P.M. Rudd (2005) Adv. Exp. Med. Biol., 564, 25-26. [Full text]
     
  627. Human immunoglobulin glycosylation and the lectin pathway of complement activation.
    J.N. Arnold, L. Royle, R.A. Dwek, P.M. Rudd and R.B. Sim (2005) Adv. Exp. Med. Biol., 564, 27-43. [Full text]
     
  628. Glycosylation and the function of the T cell co-receptor CD8.
    D.A. Shore, I.A. Wilson, R.A. Dwek and P.M. Rudd (2005) Adv. Exp. Med. Biol., 564, 71-84. [Full text]
     
  629. Immunogenicity of calreticulin-bound murine leukemia virus glycoprotein gp90.
    Y. Mimura, D. Golgher, Y. Mimura-Kimura, R.A. Dwek, P.M. Rudd and T. Elliott (2005) Adv. Exp. Med. Biol., 564, 85-94. [Full text]
     
  630. Differential glycosylation of gelatinase B from neutrophils and breast cancer cells.
    S.A. Fry, P.E. Van den Steen, L. Royle, M.R. Wormald, A.J. Leathem, G. Opdenakker, P.M. Rudd and R.A. Dwek (2005) Adv. Exp. Med. Biol., 564, 103-112. [Full text]
     
  631. New developments in treating glycosphingolipid storage diseases.
    F.M. Platt, M. Jeyakumar, U. Andersson, R.A. Dwek and T.D. Butters (2005) Adv. Exp. Med. Biol., 564, 117-126. [Full text]
     
  632. Analysis of N- and O-linked glycans of glycoproteins.
    A.H. Merry, L. Royle, C.M. Radcliffe, S.A. Astrautsova, R.A. Dwek and P.M. Rudd (2005) in "Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics, Vol 6", pp. 2333-2345, ed. L. Jorde, P. Little, M. Dunn and S. Subramaniam (J. Wiley and Sons Ltd, Chichester).

    2006 - Top-Bottom

  633. A novel Syk-dependent mechanism of platelet activation by the C-type lectin receptor CLEC-2.
    K. Suzuki-Inoue, G.L.J. Fuller, A. Garcia, J.A. Eble, S. Pohlmann, O. Inoue, T.K. Gartner, S.C. Hughan, A.C. Pearce, G.D. Laing, R.D.G. Theakston, E. Schweighoffer, N. Zitzmann, T. Morita, V.L.J. Tybulewicz, Y. Ozaki and S.P. Watson (2006) Blood, 107, 542-549. [Full text]
     
  634. Different glycan structures in prostate-specific antigen from prostate cancer sera in relation to seminal plasma PSA.
    G. Tabares, C.M. Radcliffe, S. Barrabes, M. Ramirez, R.N. Aleixandre, W. Hoesel, R.A. Dwek, P.M. Rudd, R. Peracaula, R. de Llorens (2006) Glycobiology, 16, 132-145. [Full text]
     
  635. 3,7,7a-Tri-epi-casuarine pentaacetate.
    F. Punzo, D.J. Watkin, J. Van Ameijde, G. Horne, G.W.J. Fleet, M.R. Wormald and R.J. Nash (2006) Acta Cryst., E62, o928-o930. [Full text]
     
  636. Protein-protein interactions: modeling the hepatitis C virus ion channel p7.
    G. Patargias, N. Zitzmann, R.A. Dwek and W.B. Fischer (2006) J. Med. Chem., 49, 648-655. [Full text]
     
  637. The identification and characterization of xenoantigenic nonhuman carbohydrate sequences in membrane proteins from porcine kidney.
    Y.G. Kim, S.Y. Kim, Y.M. Hur, H.S. Joo, J. Chung, D.S. Lee, L. Royle, P.M. Rudd, R.A. Dwek, D.J. Harvey and B.G. Kim (2006) Proteomics, 6, 1133-1142. [Full text]
     
  638. GC/MS of derivatised carbohydrates.
    D.J. Harvey (2006) in "Encyclopedia of Mass Spectrometry", vol. 3, pp. 129-144, ed. M.L. Gross and R.M. Caprioli (Elsevier, Oxford).
     
  639. MALDI MS of carbohydrates.
    D.J. Harvey (2006) in "Encyclopedia of Mass Spectrometry", vol. 3, pp. 148-171, ed. M.L. Gross and R.M. Caprioli (Elsevier, Oxford).
     
  640. Can P-glycoprotein influence the bioavailability of iminosugar-based glucosylceramide synthase inhibitors?
    E. Norris-Cervetto, T.D. Butters, C. Martin, S. Modok, R.A. Dwek and R. Callaghan (2006) Eur. J. Pharmacol., 530, 195-204. [Full text]
     
  641. The association of shiga-like toxin with detergent-resistant membranes is modulated by glucosylceramide and is an essential requirement in the endoplasmic reticulum for a cytotoxic effect.
    D.C. Smith, D.J. Sillence, T. Falguičres, R.M. Jarvis, L. Johannnes, J.M. Lord, F.M. Platt and L.M. Roberts (2006) Mol. Biol. Cell, 17, 1375-1387. [Full text]
     
  642. Interaction of mannan binding lectin with alpha-2 macroglobulin via exposed oligomannose glycans: A conserved feature of the thiol-ester protein family?
    J.N. Arnold, R. Wallis, A.C. Willis, D.J. Harvey, L. Royle, R.A. Dwek, P.M. Rudd and R.B. Sim (2006) J. Biol. Chem., 281, 6955-6963. [Full text]
     
  643. Variable region heavy chain glycosylation determines the anticoagulant activity of a factor VIII antibody.
    M. Jacquemin, C.M. Radcliffe, R. Lavend'homme, M.R. Wormald, L. VanderElst, G. Wallays, J. Dewaele, D. Collen, J. Vermylen, R.A. Dwek, J.M. Saint-Remy, P.M. Rudd and M. Dewerchin (2006) J. Thromb. Haemost., 4, 1047-1055. [Full text]
     
  644. Substrate reduction therapy in the infantile form of Tay-Sachs disease.
    B. Bembi, F. Marchetti, V.I. Guerci, G. Ciana, R. Addobbati, D. Grasso, R. Barone, R. Cariati, L. Fernandez-Guillen, T.D. Butters and M.G. Pittis (2006) Neurology, 66, 278-80. [Full text]
     
  645. Does rapid oligomerization of hepatitis B envelope proteins play a role in resistance to proteasome degradation and enhance chronicity?
    T.M. Block, A.S. Mehta, B.S. Blumberg and R.A. Dwek (2006) DNA Cell Biol., 25, 165-170. [Full text]
     
  646. Antiviral effect of alpha-glucosidase inhibitors on viral morphogenesis and binding properties of hepatitis C virus-like particles.
    C. Chapel, C. Garcia, P. Roingeard, N. Zitzmann, J. Dubuisson, R.A. Dwek, C. Trepo, F. Zoulim and D. Durantel (2006) J. Gen. Virol., 87, 861-871. [Full text]
     
  647. Direct deprotected glycosyl-asparagine ligation.
    K.J. Doores, Y. Mimura, R.A. Dwek, P.M. Rudd, T. Elliott and B.G. Davis (2006) Chem. Commun., 13, 1401-3. [Full text]
     
  648. Long-term non-hormonal male contraception in mice using N-butyldeoxynojirimycin.
    C.M. Walden, T.D. Butters, R.A. Dwek, F.M. Platt and A.C. van der Spoel (2006) Hum. Reprod., 21, 1309-1315. [Full text]
     
  649. Detailed structural analysis of N-glycans released from glycoproteins in SDS-PAGE gel bands using HPLC combined with exoglycosidase array digestions.
    L. Royle, C.M. Radcliffe, R.A. Dwek and P.M. Rudd (2006) in "Glycobiology Protocols", Methods in Molecular Biology, 347, pp. 125-144, ed. I. Brockhausen-Schutzbach (Humana Press).
     
  650. Remnant epitopes, autoimmunity and glycosylation.
    G. Opdenakker, C. Dillen, P. Fiten, E. Martens, I. Van Aelst, P.E. Van den Steen, I. Nelissen, S. Starckx, F.J. Descamps, J. Hu, H. Piccard, J. Van Damme, M.R. Wormald, P.M. Rudd and R.A. Dwek (2006) Biochem. Biophys. Acta, 1760, 610-615. [Full text]
     
  651. The importance of including local correlation times in the calculation of inter-proton distances from NMR measurements: ignoring local correlation times leads to significant errors in the conformational analysis of the Glca1-2Glca linkage by NMR spectroscopy.
    M. Mackeen, A. Almond, I. Cumpstey, S.C. Enis, E. Kupce, T.D. Butters, A.J. Fairbanks, R.A. Dwek and M.R. Wormald (2006) Org. Biomol. Chem. 4, 2241-2246. [Full text]
     
  652. Sialylation of urinary prothrombin fragment 1 is implicated as a contributory factor in the risk of calcium oxalate kidney stone formation.
    D. Webber, C.M. Radcliffe, L. Royle, G. Tobiasen, A.H. Merry, A.L. Rodgers, E.D. Sturrock, M.R. Wormald, D.J. Harvey, R.A. Dwek and P.M. Rudd (2006) FEBS Letters, 273, 3024-3037. [Full text]
     
  653. The hemopexin and O-glycosylated domains tune gelatinase B/MMP-9 bio-availability via inhibition and binding to cargo receptors.
    P.E. Van den Steen, I. Van Aelst, V. Hvidberg, H. Piccard, P. Fiten, C. Jacobsen, S.K. Moestrup, S. Fry, L. Royle, M.R. Wormald, R. Wallis, P.M. Rudd, R.A. Dwek and G. Opdenakker (2006) J. Biol. Chem., 281, 18626-18637. [Full text]
     
  654. Brefeldin A inhibits pestivirus release from infected cells, without affecting its assembly and infectivity.
    A. Macovei, N. Zitzmann, C. Lazar, R.A. Dwek and N. Branza-Nichita (2006) Biochem. Biophys. Res. Commun., 346, 1083-1090. [Full text]
     
  655. The characterization of the invasion phenotype of uveal melanoma tumour cells shows the presence of MUC18 and HMG-1 metastasis markers and leads to the identification of DJ-1 as a potential serum biomarker.
    M. Pardo, A. Garcia, B. Thomas, A. Pineiro, A. Akoulitchev, R.A. Dwek and N. Zitzmann (2006) Int. J. Cancer, 119, 1014-1022. [Full text]
     
  656. Crystal structure of the TCR co-receptor CD8aa in complex with monoclonal antibody YTS 105.18 Fab fragment at 2.88A resolution.
    D.A. Shore, L. Teyton, R.A. Dwek, P.M. Rudd and I.A. Wilson (2006) J. Mol. Biol., 358, 347-354. [Full text]
     
  657. Minireview - Glycolipid receptor depletion as an approach to specific antimicrobial therapy.
    M. Svensson, F.M. Platt and C. Svanborg (2006) FEMS Microbiol. Lett., 258, 1-8. [Full text]
     
  658. Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: An update covering the period 1999-2000.
    D.J. Harvey (2006) Mass Spectrom. Rev., 25, 595-662. [Full text]
     
  659. Isolation and characterization of cotiaractivase, a novel low molecular weight prothrombin activator from the venom of Bothrops cotiara.
    Y.A. Senis, P.Y. Kim, G.L.J. Fuller, Á. García, S. Prabhakar, M.C. Wilkinson, H. Brittan, N. Zitzmann, R. Wait, D.A. Warrell, S.P. Watson, A.S. Kamiguti, R.D.G. Theakston, M.E. Nesheim and G.D. Laing (2006) Biochim. Biophys. Acta, 1764, 863-871. [Full text]
     
  660. Inhibition of hybrid and complex-type glycosylation reveals the presence of the GlcNAc transferase I-independent fucosylation pathway.
    M. Crispin, D.J. Harvey, V.T. Chang, C. Yu, A.R. Aricescu, E.Y. Jones, S.J. Davis, R.A. Dwek and P.M. Rudd (2006) Glycobiology, 16, 748-756. [Full text]
     
  661. Productive folding of tyrosinase ectodomain is controlled by the transmembrane anchor.
    C.I. Popescu, A. Mares, L. Zdrentu, N. Zitzmann, R.A. Dwek and S.M. Petrescu (2006) J. Biol. Chem., 281, 21682-21689. [Full text]
     
  662. Abnormal glycosylation with hypersialylated O-glycans in patients with Sialuria.
    S. Wopereis, U.M. Abd Hamid, A.J. Critchley, L. Royle, R.A. Dwek, E. Morava, J.G. Leroy, B. Wilcken, A.J. Lagerwerf, K.M. Huijben, D.J. Lefeber, P.M. Rudd and R.A. Wevers (2006) Biochim. Biophys. Acta, 1762, 598-607. [Full text]
     
  663. Sugar determines antibody activity.
    D.R. Burton and R.A. Dwek (2006) Science, 313, 627-628. [Full text]
     
  664. Chromophore structures in the photocycle of the cyanobacterial phytochrome Cph1.
    J.J. van Thor, M. Mackeen, I. Kuprov, R.A. Dwek and M.R. Wormald (2006) Biophys. J., 91, 1811-1822. [Full text]
     
  665. Sugar amino acids at the anomeric position of carbohydrates: synthesis of spirocyclic amino acids of 6-deoxy-L-lyxofuranose.
    Y. Bleriot, M.I. Simone, M.R. Wormald, R.A. Dwek, D.J. Watkin and G.W.J. Fleet (2006) Tetrahedron: Asymmetry, 17, 2276-2286. [Full text]
     
  666. Mannan binding lectin and its interaction with immunoglobulins in health and in disease.
    J.N. Arnold, R.A. Dwek, P.M. Rudd and R.B. Sim (2006) Immunol. Lett., 106, 103-110. [Full text]
     
  667. Editorial Overview - Structural glycobiology in medicine: Carbohydrates and glycoconjugates.
    P.M. Rudd and R.A. Dwek (2006) Curr. Op. Struc. Biol., 16, 559-560. [Full text]
     
  668. Analytical strategies to investigate plant N-glycan profiles in the context of plant-made pharmaceuticals.
    M. Bardor, G. Cabrera, P.M. Rudd, R.A. Dwek, J.A. Cremata and P. Lerouge (2006) Curr. Op. Struc. Biol., 16, 576-583. [Full text]
     
  669. Structural aspects of glycomes with a focus on N-glycosylation and glycoprotein folding.
    A.J. Petrescu, M.R. Wormald and R.A. Dwek (2006) Curr. Op. Struc. Biol., 16, 600-607. [Full text]
     
  670. A global proteomics approach identifies novel phosphorylated signaling proteins in GPVI-activated platelets: Involvement of G6f, a novel platelet Grb2-binding membrane adapter.
    A. Garcia, Y.A. Senis, R. Antrobus, C.E. Hughes, R.A. Dwek, S.P. Watson and N. Zitzmann (2006) Proteomics, 6, 5332-5343. [Full text]
     
  671. Oligosaccharides modulate the apoptotic activity of glycodelin.
    R. Jayachandran, C.M. Radcliffe, L. Royle, D.J. Harvey, R.A. Dwek, P.M. Rudd and A.A. Karande (2006) Glycobiology, 16, 1052-1063. [Full text]
     
  672. Glycobiology at Oxford - a personal view.
    R.A. Dwek (2006) The Biochemist, 28(3), 4-7. [Full text]
     
  673. Glycobiology and medicine.
    P.M. Rudd and R.A. Dwek (2006) The Biochemist, 28(3), 18-21. [Full text]
     
  674. Glycobiology against viruses.
    N. Zitzmann, J.M. O'Leary and R.A. Dwek (2006) The Biochemist, 28(3), 23-26. [Full text]
     
  675. Unraveling adaptive evolution: how a single point mutation affects the protein coregulation network.
    C.G. Knight, N. Zitzmann, S. Prabhakar, R. Antrobus, R.A. Dwek, H.F. Hebestreit and P.B. Rainey (2006) Nature Genetics, 38, 1015-1022. [Full text]
     
  676. Impaired selection of invariant natural killer T cells in diverse mouse models of glycosphingolipid lysosomal storage diseases.
    S.D. Gadola, J.D. Silk, A. Jeans, P.A. Illarionov, M. Salio, G.S. Besra, R.A. Dwek, T.D. Butters, F.M. Platt and V. Cerundolo (2006) J. Exp. Med., 203, 2293-2303. [Full text]
     
  677. The glycan analysis of monoclonal antibodies secreted in deposition disorders indicates that subsets of plasma cells differentially process IgG glycans.
    L.A. Omtvedt, L. Royle, G. Husby, K. Sletten, C.M. Radcliffe, D.J. Harvey, R.A. Dwek and P.M. Rudd (2006) Arthritis and Rheumatism, 54, 3433-3440. [Full text]
     
  678. Isolation, synthesis and glycosidase inhibition profile of 3-epi-casuarine.
    J. Van Ameijde, G. Horne, M.R. Wormald, R.A. Dwek, R.J. Nash, P. Wyn Jones, E.L. Evinson and G.W.J. Fleet (2006) Tetrahedron: Asymmetry, 17, 2702-2712. [Full text]
     
  679. Structural comparison of differentially glycosylated forms of acid-beta-glucosidase, the defective enzyme in Gaucher disease.
    B. Brumshtein, M.R. Wormald, I. Silman, A.H. Futerman and J.L. Sussman (2006) Acta Cryst., D62, 1458-1465. [Full text]
     
  680. Determining the structure of glycan moieties by mass spectrometry.
    D.J. Harvey, R.A. Dwek and P.M. Rudd (2006) in "Current Protocols in Protein Science", Unit 12, pp. 12.7.1-12.7.18, ed. J.E. Coligan, B.M. Dunn, D.W. Speicher and P.T. Wingfield (John Wiley and Sons, New York). [Full text]
     
  681. Cancer associated glycoforms of gelatinase B exhibit decreased binding to galectin-3.
    S.A. Fry, P.E. Van den Steen, L. Royle, M.R. Wormald, A.J. Leathem, G. Opdenakker, J.M. McDonnell, R.A. Dwek and P.M. Rudd (2006) Biochemistry, 45, 15249-15258. [Full text]
     
  682. Human complement factor I glycosylation: Structural and functional characterisation of the N-linked oligosaccharides.
    S.A. Tsiftsoglou, J.N. Arnold, P. Roversi, M.D.M. Crispin, C.M. Radcliffe, S.M. Lea, R.A. Dwek, P.M. Rudd and R.B. Sim (2006) Biochim. Biophys. Acta, 1764, 1757-1766. [Full text]
     
  683. Differential glycosylation of polymeric and monomeric IgA: A possible role in glomerular inflammation in IgA nephropathy.
    B.D. Oortwijn, A. Roos, L. Royle, D.J. van Gijlswijk-Janssen, M.C. Faber-Krol, J.W. Eijgenraam, R.A. Dwek, M.R. Daha, P.M. Rudd and C. van Kooten (2006) J. Am. Soc. Nephrol., 17, 3529-3539. [Full text]
     
  684. Gangliosides play an important role in the organisation of CD82-enriched microdomains.
    E. Odintsova, T.D. Butters, E. Monti, H. Sprong, G. van Meer and F. Berditchevski (2006) Biochem. J., 400, 315-325. [Full text]
     
  685. Virus morphogenesis and viral entry as alternative targets for novel hepatitis C antivirals.
    C. Chapel, N. Zitzmann, F. Zoulim and D. Durantel (2006) Future Virology, 1, 197-209. [Full text]

    2007 - Top-Bottom

  686. All-or-none N-glycosylation in primate follicle-stimulating hormone beta-subunits.
    G.R. Bousfield, V.Y. Butnev, W.J. Walton, V.T. Nguyen, J. Huneidi, V. Singh, V.S.K. Kolli, D.J. Harvey and N.E. Rance (2007) Mol. Cell. Endocrinol., 260-262, 40-48. [Full text]
     
  687. Targeted identification of a unique glycan epitope of Schistosoma mansoni egg antigens using a diagnostic antibody.
    M.L.M. Robijn, C.A.M. Koeleman, M. Wuhrer, L. Royle, R. Geyer, R.A. Dwek, P.M. Rudd, A.M. Deelder and C.H. Hokke (2007) Mol. Biochem. Parasitol., 151, 148-161. [Full text]
     
  688. Severe endothelial dysfunction in the aorta of a mouse model of Fabry disease; partial prevention by N-butyldeoxynojirimycin treatment.
    T. Heare, N.J. Alp, D.A. Priestman, A.B. Kulkarni, P. Qasba, T.D. Butters, R.A. Dwek, K. Clarke, K.M. Channon and F.M. Platt (2007) J. Inherit. Metab. Dis., 30, 79-87. [Full text]
     
  689. Human follicular lymphoma cells contain oligomannose glycans in the antigen-binding site of the B cell receptor.
    C.M. Radcliffe, J.N. Arnold, D.M. Suter, M.R. Wormald, D.J. Harvey, L. Royle, Y. Mimura, Y. Kimura, R.B. Sim, S. Inogčs, M. Rodriguez-Calvillo, N. Zabalegui, A. López-Díaz de Cerio, K.N. Potter, C.I. Mockridge, R.A. Dwek, M. Bendandi, P.M. Rudd and F.K. Stevenson (2007) J. Biol. Chem., 282, 7405-7415. [Full text]
     
  690. Glycosylation of serum ribonuclease 1 indicates a major endothelial origin and reveals an increase in core fucosylation in pancreatic cancer.
    S. Barrabes, L. Pages-Pons, C.M. Radcliffe, G. Tabares, E. Fort, L. Royle, D.J. Harvey, M. Moenner, R.A. Dwek, P.M. Rudd, R. De Llorens and R. Peracaula (2007) Glycobiology, 17, 388-400. [Full text]
     
  691. Comparison of the methods for profiling glycoprotein glycans: HUPO Human Disease Glycomics/Proteome Initiative multi-institutional study.
    Y. Wada, P. Azadi, C.E. Costello, A. Dell, R.A. Dwek, H. Geyer, R. Geyer, K. Kakehi, N.G. Karlsson, K. Kato, N. Kawasaki, K.H. Khoo, S. Kim, A. Kondo, E. Lattova, Y. Mechref, E. Miyoshi, K. Nakamura, H. Narimatsu, M.V. Novotny, N.H. Packer, H. Perreault, J. Peter-Katalinic, G. Pohlentz, V.N. Reinhold, P.M. Rudd, A. Suzuki and N. Taniguchi (2007) Glycobiology, 17, 411-422. [Full text]
     
  692. The impact of glycosylation on the biological function and structure of human immunoglobulins.
    J.N. Arnold, M.R. Wormald, R.B. Sim, P.M. Rudd and R.A. Dwek (2007) Ann. Rev. Immunol., 25, 21-50. [Full text] [Supplementary data]
     
  693. Glycobiology - discovery, diagnostics and drugs.
    T.M. Block, A.S. Mehta, P.M. Rudd, M.R. Wormald, D.R. Burton, I.A. Wilson, S.M. Petrescu, F.M. Platt, N. Zitzmann, T.D. Butters and R.A. Dwek (2007) in "Glycobiology", pp.8-11, ed. C. Sansom and O. Markman (Scion Publishing Ltd, UK). [Full text]
     
  694. Structural determination of N-linked glycans by matrix-assisted laser desorption/ionization and electrospray ionization mass spectrometry.
    D.J. Harvey (2007) in "Glycobiology", pp.62-77, ed. C. Sansom and O. Markman (Scion Publishing Ltd, UK). [Full text]
     
  695. Proteomics in uveal melanoma research: opportunities and challenges in biomarker discovery.
    M. Pardo, R.A. Dwek and N. Zitzmann (2007) Expert Rev. Proteomics, 4, 273-286. [Full text]
     
  696. Crystallographic, thermodynamic, and molecular modelling studies of the mode of binding of oligosaccharides to the potent antiviral protein griffithsin.
    N.E. Ziolkowska, S.R. Shenoy, B.R. O'Keefe, J.B. McMahon, K.E. Palmer, R.A. Dwek, M.R. Wormald and A. Wlodawer (2007) Proteins, 67, 661-670. [Full text]
     
  697. Synthesis of and NMR studies on the four diastereomeric 1-deoxy-D-ketohexoses.
    N.A. Jones, S.F. Jenkinson, R. Soengas, M. Fanefjord, M.R. Wormald, R.A. Dwek, G.P. Kiran, R. Devendar, G. Takata, K. Morimoto, K. Izumori and G.W.J. Fleet (2007) Tetrahedron: Asymmetry, 18, 774-786. [Full text]
     
  698. Reduction of the infectivity of hepatitis C virus pseudoparticles by incorporation of misfolded glycoproteins induced by glucosidase inhibitors.
    C. Chapel, C. Garcia, B. Bartosch, P. Roingeard, N. Zitzmann, F.L. Cosset, J. Dubuisson, R.A. Dwek, C. Trépo, F. Zoulim and D. Durantel (2007) J. Gen. Virol., 88, 1133-1143. [Full text]
     
  699. Implications for invariant natural killer T cell ligands due to the restricted presence of isoglobotrihexosylceramide in mammals.
    A.O. Speak, M. Salio, D.C.A. Neville, J. Fontaine, D.A. Priestman, N. Platt, T. Heare, T.D. Butters, R.A. Dwek, F. Trottein, M.A. Exley, V. Cerundolo and F.M. Platt (2007) Proc. Natl. Acad. Sci. USA, 104, 5971-5976. [Full text]
     
  700. Folding of an MHC class II-restricted tumor antigen controls its antigenicity via MHC-guided processing.
    Y. Mimura, Y. Mimura-Kimura, K.J. Doores, D. Golgher, B.G. Davis, R.A. Dwek, P.M. Rudd and T. Elliott (2007) Proc. Natl. Acad. Sci. USA, 104, 5983-5988. [Full text]
     
  701. Stem cells act through multiple mechanisms to benefit mice with neurodegenerative metabolic disease.
    J.P. Lee, M. Jeyakumar, R. Gonzalez, H. Takahashi, P.J. Lee, R.C. Baek, D. Clark, H. Rose, G. Fu, J. Clarke, S. McKercher, J. Meerloo, F.J. Muller, K.I. Park, T.D. Butters, R.A. Dwek, P. Schwartz, G. Tong, D. Wenger, S.A. Lipton, T.N. Seyfried, F.M. Platt and E.Y. Snyder (2007) Nature Medicine, 13, 439-447. [Full text]
     
  702. Glycoprotein structural genomics: solving the glycosylation problem.
    V.T. Chang, M. Crispin, A.R. Aricescu, D.J. Harvey, J.E. Nettleship, J.A. Fennelly, C. Yu, K.S. Boles, E.J. Evans, D.I. Stuart, R.A. Dwek, E.Y. Jones, R.J. Owens and S.J. Davis (2007) Structure, 15, 267-273. [Full text]
     
  703. Pharmacotherapeutic strategies using small molecules for the treatment of glycolipid lysosomal storage disorders.
    T.D. Butters (2007) Expert Opin. Pharmacother., 8, 427-435. [Full text]
     
  704. A comprehensive proteomics and genomics analysis reveals novel transmembrane proteins in human platelets and mouse megakaryocytes including G6b-B, a novel immunoreceptor tyrosine-based inhibitory motif protein.
    Y.A. Senis, M.G. Tomlinson, A. Garcia, S. Dumon, V.L. Heath, J. Herbert, S.P. Cobbold, J.C. Spalton, S. Ayman, R. Antrobus, N. Zitzmann, R. Bicknell, J. Frampton, K. Authi, A. Martin, M.J. Wakelam and S.P. Watson (2007) Mol. Cell Proteomics, 6, 548-564. [Full text]
     
  705. Disruption of alpha-mannosidase processing induces non-canonical hybrid-type glycosylation.
    M. Crispin, A.R. Aricescu, V.T. Chang, E.Y. Jones, D.I. Stuart, R.A. Dwek, S.J. Davis and D.J. Harvey (2007) FEBS Letters, 581, 1963-1968. [Full text]
     
  706. Review - Exploiting the defensive sugars of HIV-1 for drug and vaccine design.
    C.N. Scanlan, J. Offer, N. Zitzmann and R.A. Dwek (2007) Nature, 446, 1038-1045. [Full text]
     
  707. Efficient synthesis from D-lyxonolactone of 2-acetamido-1,4-imino-1,2,4-trideoxy-L-arabinitol LABNAc, a potent pyrrolidine inhibitor of hexosaminidases.
    J.S.S. Rountree, T.D. Butters, M.R. Wormald, R.A. Dwek, N. Asano, K. Ikeda, E.L. Evinson, R.J. Nash and G.W.J. Fleet (2007) Tetrahedron Letters, 48, 4287-4291. [Full text]
     
  708. The sensitivity of murine spermiogenesis to miglustat is a quantitative trait: a pharmacogenetic study.
    W. Bone, C.M. Walden, M. Fritsch, U. Voigtmann, E. Leifke, U. Gottwald, S.D. Boomkamp, F.M. Platt and A.C. van der Spoel (2007) Reprod. Biol. Endocrinol., 5:1. [Full text]
     
  709. Biomarker discovery from uveal melanoma secretomes: Identification of gp100 and cathepsin D in patient serum.
    M. Pardo, A. Garcia, R. Antrobus, M.J. Blanco, R.A. Dwek and N. Zitzmann (2007) J. Proteome Res., 6, 2802-2811. [Full text]
     
  710. Synthesis 2-C-branched derivatives of D-mannose: 2-C-aminomethyl-D-mannose binds to the human C-type lectin DC-SIGN with affinity greater than an order of magnitude compared to that of D-mannose.
    D.A. Mitchell, N.A. Jones, S.J. Hunter, J.M.D. Cook, S.F. Jenkinson, M.R. Wormald, R.A. Dwek and G.W.J. Fleet (2007) Tetrahedron: Asymmetry, 18, 1502-1510. [Full text]
     
  711. The goat mammary glandular epithelial (GMGE) cell line promotes polyfucosylation and N,N'-diacetyllactosediaminylation of N-glycans linked to recombinant human erythropoietin.
    O. Sanchez, R. Montesino, J.R. Toledo, E. Rodriguez, D. Diaz, L. Royle, P.M. Rudd, R.A. Dwek, G.J. Gerwig, J.P. Kamerling, D.J. Harvey and J.A. Cremata (2007) Arch. Biochem. Biophys., 464, 322-334. [Full text]
     
  712. Inhibition of mammalian glycan biosynthesis produces non-self antigens for a broadly neutralising, HIV-1 specific antibody.
    C.N. Scanlan, G.E. Ritchie, K. Baruah, M. Crispin, D.J. Harvey, B.B. Singer, L. Lucka, M.R. Wormald, P. Wentworth Jr, N. Zitzmann, P.M. Rudd, D.R. Burton and R.A. Dwek (2007) J. Mol. Biol., 372, 16-22. [Full text]
     
  713. Antiviral effects of amantadine and iminosugar derivatives against hepatitis C virus.
    E. Steinmann, T. Whitfield, S. Kallis, R.A. Dwek, N. Zitzmann, T. Pietschmann and R. Bartenschlager (2007) Hepatology, 46, 330-338. [Full text]
     
  714. Treatment of hepatitis B virus-infected cells with alpha-glucosidase inhibitors results in production of virions with altered molecular composition and infectivity.
    C. Lazar, D. Durantel, A. Macovei, N. Zitzmann, F. Zoulim, R.A. Dwek and N. Branza-Nichita (2007) Antiviral Res., 76, 30-37. [Full text]
     
  715. Gaucher disease.
    T.D. Butters (2007) Curr. Op. Chem. Biol., 11, 412-418. [Full text]
     
  716. Novel serum biomarker candidates for liver fibrosis in Hepatitis C patients.
    B. Gangadharan, R. Antrobus, R.A. Dwek and N. Zitzmann (2007) Clin.Chem., 53, 1792-1799. [Full text]
     
  717. Contrasting glycosylation profiles between Fab and Fc of a human IgG protein studied by electrospray ionization mass spectrometry.
    Y. Mimura, P.R. Ashton, N. Takahashi, D.J. Harvey and R. Jefferis (2007) J. Immunol. Meth., 326, 116-126. [Full text]
     
  718. Changes of serum glycans during sepsis and acute pancreatitis.
    O. Gornik, L. Royle, D.J. Harvey, C.M. Radcliffe, R. Saldova, R.A. Dwek, P.M. Rudd and G. Lauc (2007) Glycobiology, 17, 1321-1332. [Full text]
     
  719. Ovarian cancer is associated with changes in glycosylation in both acute-phase proteins and IgG.
    R. Saldova, L. Royle, C.M. Radcliffe, U.M. Abd Hamid, R. Evans, J.N. Arnold, R.E. Banks, R. Hutson, D.J. Harvey, R. Antrobus, S.M. Petrescu, R.A. Dwek and P.M. Rudd (2007) Glycobiology, 17, 1344-1356. [Full text]
     
  720. Separation-based glycoprofiling approaches using fluorescent labels.
    P.J. Domann, A.C. Pardos-Pardos, D.L. Fernandes, D.I.R. Spencer, C.M. Radcliffe, L. Royle, R.A. Dwek and P.M. Rudd (2007) Proteomics, 7(S1), 70-76. [Full text]
     
  721. Crystal structures of complexes of N-butyl- and N-nonyl-deoxynojirimycin bound to acid-beta-glucosidase: Insights into the mechanism of chemical chaperone action in gaucher disease.
    B. Brumshtein, H.M. Greenblatt, T.D. Butters, Y. Shaaltiel, D. Aviezer, I. Silman, A.H. Futerman and J.L. Sussman (2007) J. Biol. Chem., 282, 29052-29058. [Full text]
     
  722. Accumulation of glucosylceramide in murine testis, caused by inhibition of beta-glucosidase 2: implications for spermatogenesis.
    C.M. Walden, R. Sandhof, C.C. Chuang, Y. Yildiz, T.D. Butters, R.A. Dwek, F.M. Platt and A.C. van der Spoel (2007) J. Biol. Chem., 282, 32655-32664. [Full text]
     
  723. Imino sugar inhibitors for treating the lysosomal glycosphingolipidoses.
    T.D. Butters (2007) in "Iminosugars: from synthesis to therapeutic applications", pp. 249-268, ed. O. Compain and P. Martin (John Wiley & Sons Ltd., Chichester, UK).
     
  724. Substrate reduction therapy.
    F.M. Platt and T.D. Butters (2007) in "Lysosomal storage disorders", pp. 153-168, ed. J.A. Barranger and M.A. Cabrera-Salazar (Springer-Verlag, London Ltd., Guildford, UK).
     
  725. Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity.
    S.S. Ng, K.L. Kavanagh, M.A. McDonough, D. Butler, E.S. Pilka, B.M.R. Lienard, J.E. Bray, P. Savitsky, O. Gileadi, F. von Delft, N.R. Rose, J. Offer, J.C. Scheinost, T. Borowski, M. Sundstrom, C.J. Schofield and U. Oppermann (2007) Nature, 448, 87-92. [Full text]
     
  726. Cyclin B and cyclin A confer different substrate recognition properties on CDK2.
    N.R. Brown, E.D. Lowe, E. Petri, V. Skamnaki, R. Antrobus and L.N. Johnson (2007) Cell Cycle, 6, 1350-1359. [Full text] [Supplementary data]
     
  727. Two-dimensional gel electrophoresis in platelet proteomics research.
    A. Garcia (2007) Methods Mol. Med., 139, 339-353. [Full text]
     
  728. Platelet genomics and proteomics.
    A. Garcia, Y. Senis, M.G. Tomlinson and S.P. Watson (2007) in "Platelets", 2nd edition, pp. 99-116, ed A.D. Michelson (Elsevier/Academic Press, USA). [Full text]

    2008 - Top-Bottom

  729. Synthesis of the naringinase inhibitors L-swainsonine and related 6-C-methyl-L-swainsonine analogues: (6R)-C-methyl-L-swainsonine is a more potent inhibitor of L-rhamnosidase by an order of magnitude than L-swainsonine.
    A.E. Hakansson, J. van Ameijde, G. Horne, R.J. Nash, M.R. Wormald, A. Kato, G.S. Besra, S. Gurchad and G.W.J. Fleet (2008) Tetrahedron Letters, 49, 179-184. [Full text]
     
  730. Glucosylated free oligosaccharides are biomarkers of endoplasmic reticulum alpha-glucosidase inhibition.
    D.S. Alonzi, D.C.A. Neville, R.H. Lachmann, R.A. Dwek and T.D. Butters (2008) Biochem. J., 409, 571-580. [Full text]
     
  731. Monosialylated biantennary N-glycoforms containing GalNAc-GlcNAc antennae predominate when human EPO is expressed in goat milk.
    R. Montesino, J.R. Toledo, O. Sanchez, A. Sanchez, D.J. Harvey, L. Royle, R.A. Dwek, P.M. Rudd, G.J. Gerwig, J.P. Kamerling and J.A. Cremata (2008) Arch. Biochem. Biophys., 470, 163-175. [Full text]
     
  732. Increased levels of galactose-deficient anti-gal Immunoglobulin G in the sera of Hepatitis C virus-infected individuals with fibrosis and cirrhosis.
    A.S. Mehta, R.E. Long, M.A. Comunale, L. Rodemich, J. Krakover, R. Philip, J.A. Marrero, R.A. Dwek and T.M. Block (2008) J. Virol., 82, 1259-1270. [Full text]
     
  733. New synthetic seven-membered 1-azasugars displaying potent inhibition towards glycosidases and glucosylceramide transferase.
    H. Li, T. Liu, Y. Zhang, S. Favre, C. Bello, P. Vogel, T.D. Butters, N.G. Oikonomakos, J. Marrot and Y. Blériot (2008) ChemBioChem, 9, 253-60. [Full text]
     
  734. Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: An update covering the period 2001-2002.
    D.J. Harvey (2008) Mass Spectrom. Rev., 27, 125-201. [Full text]
     
  735. The mannose receptor mediates dengue virus infection of macrophages.
    J.L. Miller, B.J.M. deWet, L. Martinez-Pomares, C.M. Radcliffe, R.A. Dwek, P.M. Rudd and S. Gordon (2008) PLoS Pathogens, 4, e17. [Full text]
     
  736. Remarkable selective glycosylation of the immunoglobulin variable region in follicular lymphoma.
    K.J. McCann, C.H. Ottensmeier, A. Callard, C.M. Radcliffe, D.J. Harvey, R.A. Dwek, P.M. Rudd, B.J. Sutton, P. Hobby and F.K. Stevenson (2008) Mol. Immunol., 45, 1567-1572. [Full text]
     
  737. High-throughput screening of glycan-binding proteins using miniature pig kidney N-glycan-immobilized beads.
    Y.G. Kim, D.S. Shin, Y.H. Yang, G.C. Gil, C.G. Park, Y. Mimura, D.K.C. Cooper, P.M. Rudd, R.A. Dwek, Y.S. Lee and B.G. Kim (2008) Chemistry and Biology, 15, 215-223. [Full text]
     
  738. Differentiation between isomeric triantennary N-linked glycans by negative ion tandem mass spectrometry and confirmation of glycans containing galactose attached to the bisecting (b1-4-GlcNAc) residue in N-glycans from IgG.
    D.J. Harvey, M. Crispin, C.N. Scanlan, B.B. Singer, L. Lucka, V.T. Chang, C.M. Radcliffe, S. Thobhani, C.T. Yuen and P.M. Rudd (2008) Rapid Commun. Mass Spectrom., 22, 1047-1052. [Full text]
     
  739. Commentary - Making autoantibodies safe.
    C.N. Scanlan, D.R. Burton and R.A. Dwek (2008) Proc. Natl. Acad. Sci. USA, 105, 4081-4082. [Full text]
     
  740. Oxford University’s first spin-off company - Oxford GlycoSystems.
    R.A. Dwek (2008) The Biochemist, 30(2), 4-7. [Full text]
     
  741. The Oxford model - the threats and opportunities of commercializing university research.
    T. Cook, R.A. Dwek, T. Hockaday and B.S. Blumberg (2008) The Biochemist, 30(2), 18-23. [Full text]
     
  742. Isomerization of deoxyhexoses: green bioproduction of 1-deoxy-D-tagatose from L-fucose and of 6-deoxy-D-tagatose from D-fucose using Enterobacter agglomerans strain 221e.
    A. Yoshihara, S. Haraguchi, P. Gullapalli, D. Rao, K. Morimoto, G. Takata, N. Jones, S.F. Jenkinson, M.R. Wormald, R.A. Dwek, G.W.J. Fleet and K. Izumori (2008) Tetrahedron: Asymmetry, 19, 739-745. [Full text]
     
  743. HPLC-based analysis of serum N-glycans on a 96 well plate platform with dedicated database software.
    L. Royle, M.P. Campbell, C.M. Radcliffe, D.M. White, D.J. Harvey, J.L. Abrahams, Y.G. Kim, G.W. Henry, N.A. Shadick, M.E. Weinblatt, D.M. Lee, P.M. Rudd and R.A. Dwek (2008) Anal. Biochem., 376, 1-12. [Full text]
     
  744. Structural and quantitative analysis of N-linked glycans by matrix-assisted laser desorption ionization and negative ion nanospray mass spectrometry.
    D.J. Harvey, L. Royle, C.M. Radcliffe, P.M. Rudd and R.A. Dwek (2008) Anal. Biochem., 376, 44-60. [Full text]
     
  745. Towards the biotechnological isomerization of branched sugars: D-Tagatose-3-epimerase equilibrates both enantiomers of 4-C-methyl-ribulose with both enantiomers of 4-C-methyl-xylulose.
    D. Rao, A. Yoshihara, P. Gullapalli, K. Morimoto, G. Takata, F.P. da Cruz, S.F. Jenkinson, M.R. Wormald, R.A. Dwek, G.W.J. Fleet and K. Izumori (2008) Tetrahedron Letters, 49, 3316-3321. [Full text]
     
  746. Altered glycosylation of proteins in cancer: What is the potential for new anti-tumour strategies?
    S.A. Brooks, T.M. Carter, L. Royle, D.J. Harvey, S.A. Fry, C. Kinch, R.A. Dwek and P.M. Rudd (2008) Anti-Cancer Agents Med. Chem., 8, 2-21. [Full text]
     
  747. Iminosugars in combination with interferon and ribavirin permanently eradicate non-cytopathic bovine viral diarrhoea virus from persistently infected cells.
    S.D. Woodhouse, C. Smith, M. Michelet, N. Branza-Nichita, M. Hussey, R.A. Dwek and N. Zitzmann (2008) Antimicrobial Agents and Chemotherapy, 52, 1820-1828. [Full text]
     
  748. A microtubule interactome: Complexes with roles in cell cycle and mitosis.
    J.R. Hughes, A.M. Meireles, K.H. Fisher, A. Garcia, P.R. Antrobus, A. Wainman, N. Zitzmann, C. Deane, H. Ohkura and J.G. Wakefield (2008) PLoS Biol., 6, e98. [Full text]
     
  749. Plant N-glycan profiling of minute amounts of material.
    M. Séveno, G. Cabrera, A. Triguero, C. Burel, J. Leprince, C. Rihouey, L.P. Vézina, M.A. D'Aoust, P.M. Rudd, L. Royle, R.A. Dwek, D.J. Harvey, P. Lerouge, J.A. Cremata and M. Bardor (2008) Anal. Biochem., 379, 66-72. [Full text]
     
  750. Genes contributing to prion pathogenesis.
    G. Tamgüney, K. Giles, D.V. Glidden, P. Lessard, H. Wille, P. Tremblay, D.F. Groth, F. Yehiely, C. Korth, R.C. Moore, J. Tatzelt, E. Rubenstein, C. Boucheix, X. Yang, P. Stanley, M.P. Lisanti, R.A. Dwek, P.M. Rudd, J. Moskovitz, C.J. Epstein, T.C. Dawson Cruz, W.A. Kuziel, N. Maeda, J. Sap, K. Hsiao Ashe, G.A. Carlson, I. Tesseur, T. Wyss-Coray, L. Mucke, K.H. Weisgraber, R.W. Mahley, F.E. Cohen and S.B. Prusiner (2008) J. Gen. Virol., 89, 1777-1788. [Full text]
     
  751. N-butyldeoxynojirimycin causes weight loss as a result of appetite suppression in lean and obese mice.
    D.A. Priestman, A.C. van der Spoel, T.D. Butters, R.A. Dwek and F.M. Platt (2008) Diabetes Obesity Metab., 10, 159-166. [Full text]
     
  752. GlycoBase and autoGU: tools for HPLC-based glycan analysis.
    M.P. Campbell, L. Royle, C.M. Radcliffe, R.A. Dwek and P.M. Rudd (2008) Bioinformatics, 24, 1214-1216. [Full text]
     
  753. A glycoconjugate antigen based on the recognition motif of a broadly neutralizing human immunodeficiency virus antibody, 2G12, is immunogenic but elicits antibodies unable to bind to the self glycans of gp120.
    R.D. Astronomo, H.K. Lee, C.N. Scanlan, R. Pantophlet, C.Y. Huang, I.A. Wilson, O. Blixt, R.A. Dwek, C.H. Wong and D.R. Burton (2008) J. Virol., 82, 6359-6368. [Full text]
     
  754. Beneficial effects of substrate reduction therapy in a mouse model of GM1 gangliosidosis.
    E. Elliot-Smith, A.O. Speak, E. Lloyd-Evans, D.A. Smith, A.C. van der Spoel, M. Jeyakumar, T.D. Butters, R.A. Dwek, A. d'Azzo and F.M. Platt (2008) Molecular Genetics and Metabolism, 94, 204-211. [Full text]
     
  755. The O-linked glycosylation of secretory/shed MUC1 from advanced breast cancer patient serum.
    S.J. Storr, L. Royle, C.J. Chapman, U.M. Abd Hamid, J.F. Robertson, A. Murray, R.A. Dwek and P.M. Rudd (2008) Glycobiology, 18, 456-462. [Full text]
     
  756. Commercialising university research: Threats and opportunities - the Oxford model
    T. Cook, R.A. Dwek, B.S. Blumberg and T. Hockaday (2008) Capitalism and Society, 3(1), article 4. [Full text]
     
  757. Structural analysis of alpha-Gal and new non-Gal carbohydrate epitopes from specific pathogen-free miniature pig kidney.
    Y.G. Kim, G.C. Gil, D.J. Harvey and B.G. Kim (2008) Proteomics, 8, 2596-2610. [Full text]
     
  758. Green syntheses of new 2-C-methyl aldohexoses and 5-C-methyl ketohexoses: D-tagatose-3-epimerase (DTE) - a promiscuous enzyme.
    N.A. Jones, D. Rao, A. Yoshihara, P. Gullapalli, K. Morimoto, G. Takata, S.J. Hunter, M.R. Wormald, R.A. Dwek, K. Izumori and G.W.J. Fleet (2008) Tetrahedron: Asymmetry, 19, 1904-1918. [Full text]
     
  759. Editorial - A stronger voice for biology.
    R.A. Dwek (2008) Biologist, 55, 131. [Full text]
     
  760. Growing together.
    N. Rothwell, R.A. Dwek, A. Malcolm and R. Dyer (2008) Biologist, 55, 172. [Full text]
     
  761. N-butyldeoxynojirimycin is a broadly effective anti-HIV therapy significantly enhanced by targeted liposome delivery.
    S. Pollock, R.A. Dwek, D.R. Burton and N. Zitzmann (2008) AIDS, 22, 1961-1969. [Full text]
     
  762. Human invariant NKT cells display alloreactivity instructed by invariant TCR-CD1d interaction and killer Ig receptors.
    S. Patterson, A. Chaidos, D.C.A. Neville, A. Poggi, T.D. Butters, I.A. Roberts and A. Karadimitris (2008) J. Immunol., 181, 3268-3276. [Full text]
     
  763. Cholesterol seco-sterol-induced aggregation of methylated amyloid-beta peptides - Insights into aldehyde-initiated fibrillization of amyloid-beta.
    J.C. Scheinost, H. Wang, G.E. Boldt, J. Offer and P. Wentworth Jr (2008) Angew. Chem. Int. Ed., 47, 3919-3922. [Full text]
     
  764. Evaluation of the serum N-linked glycome for the diagnosis of cancer and chronic inflammation.
    J.N. Arnold, R. Saldova, U.M.A. Hamid and P.M. Rudd (2008) Proteomics, 8, 3284-3293. [Full text]
     
  765. Anti body-catalyzed water-oxidation pathway.
    P. Wentworth Jr and D.P. Witter (2008) Pure Appl. Chem., 80, 1849-1858. [Full text]
     
  766. Malectin: a novel carbohydrate-binding protein of the endoplasmic reticulum and a candidate player in the early steps of protein N-glycosylation.
    T. Schallus, C. Jaeckh, K. Fehér, A.S. Palma, Y. Liu, J.C. Simpson, M. Mackeen, G. Stier, T.J. Gibson, T. Feizi, T. Pieler and C. Muhle-Goll (2008) Mol. Biol. Cell, 19, 3404-3414. [Full text]
     
  767. A peptide inhibitor of HIV-1 neutralizing antibody 2G12 is not a structural mimic of the natural carbohydrate epitope on gp120.
    A. Menendez, D.A. Calarese, R.L. Stanfield, K.C. Chow, C.N. Scanlan, R. Kunert, H. Katinger, D.R. Burton, I.A. Wilson and J.K. Scott (2008) FASEB J., 22, 1380-1392. [Full text]
     
  768. Antigenic mimicry of the HIV envelope by AIDS-associated pathogens.
    D.C. Dunlop, A. Ulrich, B.J. Appelmelk, D.R. Burton, R.A. Dwek, N. Zitzmann and C.N. Scanlan (2008) AIDS, 22, 2214-2217. [Full text]
     
  769. Glycosphingolipid disorders of the brain.
    S.D. Boomkamp and T.D. Butters (2008) in "Subcellular Biochemistry: Vol. 49, Lipids in Health and Disease", pp.441-467, ed. P.J. Quinn and X. Wang (Springer).
     
  770. Glycoprotein Analysis.
    T.D. Butters and D.C.A. Neville (2008) in "Molecular Biomethods Handbook", pp.495-513, ed. J.M. Walker and R. Rapley (Humana Press Inc., Totowa, NJ).
     
  771. Structural characterization of the 1918 influenza H1N1 neuraminidase.
    X. Xu, X. Zhu, R.A. Dwek, J. Stevens and I.A. Wilson (2008) J. Virol., 82, 10493-10501. [Full text]
     
  772. Crystal structure and carbohydrate analysis of Nipah Virus attachment alycoprotein: A template for antiviral and vaccine design.
    T.A. Bowden, M. Crispin, D.J. Harvey, A.R. Aricescu, J.M. Grimes, E.Y. Jones and D.I. Stuart (2008) J. Virol., 82, 11628-11636. [Full text]
     
  773. A strategy to reveal potential glycan markers and glycoforms of serum glycoproteins associated with breast cancer progression.
    U.M. Abd Hamid, L. Royle, R. Saldova, C.M. Radcliffe, D.J. Harvey, S.J. Storr, M. Pardo, R. Antrobus, C.J. Chapman, N. Zitzmann, J.F. Robertson, R.A. Dwek, P.M. Rudd (2008) Glycobiology, 18, 1105-1118. [Full text]
     
  774. Glycosylation changes on serum glycoproteins in ovarian cancer may contribute to disease pathogenesis.
    R. Saldova, M.R. Wormald, R.A. Dwek and P.M. Rudd (2008) Disease Markers, 25, 219-232. [Full text]
     
  775. Glycan structures of ocular surface mucins in man, rabbit and dog display species differences.
    L. Royle, E. Matthews, A. Corfield, M. Berry, P.M. Rudd, R.A. Dwek and S.D. Carrington (2008) Glycoconj. J., 25, 763-773. [Full text]
     
  776. Identification of a novel higher molecular weight isoform of USP7/HAUSP that interacts with the Herpes simplex virus type-1 immediate early protein ICP0.
    R. Antrobus and C. Boutell (2008) Virus Res., 137, 64-71. [Full text] [Supplementary data]
     
  777. Plk1 activation by Ste20-like kinase (Slk) phosphorylation and polo-box phosphopeptide binding assayed with the substrate translationally controlled tumor protein (TCTP).
    T.M. Johnson, R. Antrobus and L.N. Johnson (2008) Biochemistry, 47, 3688-3696. [Full text]

    2009 - Top-Bottom

  778. Derivatization of sialic acids for stabilization in matrix-assisted laser desorption/ionization mass spectrometry and concomitant differentiation of alpha(2-3) and alpha(2-6) isomers.
    S.F. Wheeler, P. Domann and D.J. Harvey (2009) Rapid Commun. Mass Spectrom., 23, 303-312. [Full text]
     
  779. Proteomic analysis of HepaRG cells: a novel cell line that supports Hepatitis B virus infection.
    R. Narayan, B. Gangadharan, O. Hantz, R. Antrobus, Á. García, R.A. Dwek and N. Zitzmann (2009) J. Proteome Res., 8, 118-122. [Full text]
     
  780. Application of negative ionMS/MS to the identification of N-glycans released from carcinoembryonic antigen cell adhesion molecule 1 (CEACAM1).
    D.J. Harvey, K. Baruah and C.N. Scanlan (2009) J. Mass. Spectrom., 44, 50-60. [Full text]
     
  781. Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: An update for 2003-2004.
    D.J. Harvey (2009) Mass Spectrom. Rev., 28, 273-361. [Full text]
     
  782. Determination of pore-lining residues in the Hepatitis C virus p7 protein.
    C.F. Chew, R. Vijayan, J. Chang, N. Zitzmann and P.C. Biggin (2009) Biophys. J., 96, L10-L12. [Full text]
     
  783. N-Glycosylation pattern of E2 glycoprotein from classical swine fever virus.
    R. Montesino, J.R. Toledo, O. Sanchez, Y. Zamora, M. Barrera, L. Royle, P.M. Rudd, R.A. Dwek, D.J. Harvey, J.A. Cremata (2009) J. Proteome Res., 8, 546-555. [Full text]
     
  784. Development of a single column method for the separation of lipid- and protein-derived oligosaccharides.
    D.C.A. Neville, R.A. Dwek and T.D. Butters (2009) J. Proteome Res., 8, 681-687. [Full text]
     
  785. Carbasugar-thioether pseudodisaccharides related to N-glycan biosynthesis.
    I. Cumpstey, D.S. Alonzi and T.D. Butters (2009) Carbohydr. Res., 344, 454-459. [Full text]
     
  786. The conformational properties of the Glc3Man unit suggest conformational biasing within the chaperone-assisted glycoprotein folding pathway.
    M.M. Mackeen, A. Almond, M. Deschamps, I. Cumpstey, A.J. Fairbanks, C. Tsang, P.M. Rudd, T.D. Butters, R.A. Dwek and M.R. Wormald (2009) J. Mol. Biol., 387, 335-347. [Full text] [Supplementary data]
     
  787. Antibodies and antigens: It’s all about the numbers game.
    R.A. Dwek (2009) Proc. Natl. Acad. Sci. USA, 106, 2087-2088. [Full text]
     
  788. Probing replacement of pyrophosphate via click chemistry; synthesis of UDP-sugar analogues as potential glycosyl transferase inhibitors.
    K.K. Yeoh, T.D. Butters, B.L. Wilkinson and A.J. Fairbanks (2009) Carbohydr. Res., 344, 586-591. [Full text]
     
  789. Design, synthesis, and biological evaluation of enantiomeric b-N-acetylhexosaminidase inhibitors LABNAc and DABNAc as potential agents against Tay-Sachs and Sandhoff disease.
    J.S.S. Rountree, T.D. Butters, M.R. Wormald, S.D. Boomkamp, R.A. Dwek, N. Asano, K. Ikeda, E.L. Evinson, R.J. Nash and G.W.J. Fleet (2009) ChemMedChem, 4, 378-392. [Full text]
     
  790. Improved cellular inhibitors for glycoprotein processing a-glucosidases: biological characterisation of alkyl- and arylalkyl-N-substituted deoxynojirimycins.
    D.S. Alonzi, R.A. Dwek and T.D. Butters (2009) Tetrahedron: Asymmetry, 20, 897-901. [Full text]
     
  791. A concise approach to the synthesis of all twelve 5-deoxyhexoses: D-Tagatose-3-epimerase - a reagent that is both specific and general.
    D. Rao, D. Best, A. Yoshihara, P. Gullapalli, K. Morimoto, M.R. Wormald, F.X. Wilson, K. Izumori and G.W.J. Fleet (2009) Tetrahedron Letters, 50, p.3559-3563. [Full text]
     
  792. Synthesis and biological characterisation of novel N-alkyl-deoxynojirimycin alpha-glucosidase inhibitors.
    A.J. Rawlings, H. Lomas, A.W. Pilling, M.J. Lee, D.S. Alonzi, J.S.S. Rountree, S.F. Jenkinson, G.W.J. Fleet, R.A. Dwek, J.H. Jones and T.D. Butters (2009) ChemBioChem, 10, 1101-1105. [Full text]
     
  793. A chemical approach to immunoprotein engineering: chemoselective functionalization of thioester proteins in their native state.
    M.A. Cole, S.E. Tully, A.W. Dodds, J.N. Arnold, G.E. Boldt, R.B. Sim, J. Offer and P. Wentworth Jr (2009) ChemBioChem, 10, 1340-1343. [Full text]
     
  794. The natural products beauveriolide I and III: a new class of beta-amyloid lowering compounds.
    D.P. Witter, Y. Chen, J.K. Rogel, G.E. Boldt and P. Wentworth Jr (2009) ChemBioChem, 10, 1344-1347. [Full text]
     
  795. Detailed N-glycan analysis of mannose receptor purified from murine spleen indicates tissue specific sialylation.
    Y. Su, L. Royle, C.M. Radcliffe, D.J. Harvey, R.A. Dwek, L. Martinez-Pomares, P.M. Rudd (2009) Biochem. Biophys. Res. Commun., 384, 436-443. [Full text]
     
  796. Carbohydrate and domain architecture of an immature antibody glycoform exhibiting enhanced effector functions.
    M. Crispin, T.A. Bowden, C.H. Coles, K. Harlos, A.R. Aricescu, D.J. Harvey, D.I. Stuart and E.Y. Jones (2009) J. Mol. Biol., 387, 1061-1066. [Full text]
     
  797. Book review - Glycobiology: Moving into the Mainstream (Essentials of Glycobiology: Second Edition)
    R.A. Dwek (2009) Cell, 137, 1175-1176. [Full text]
     
  798. Design and synthesis of acetamido tri- and tetra-hydroxyazepanes: Potent and selective beta-N-acetylhexosaminidase inhibitors.
    H. Li, F. Marcelo, C. Bello, P. Vogel, T.D. Butters, A.P. Rauter, Y. Zhang, M. Sollogoub and Y. Blériot (2009) Bioorg. Med. Chem., 17, 5598-5604. [Full text]
     
  799. Glucosylceramide synthase inhibitors sensitise CLL cells to cytotoxic agents without reversing P-gp functional activity.
    G. Gerrard, T.D. Butters, K. Ganeshaguru and A.B. Mehta (2009) Eur. J. Pharmacol., 609, 34-39. [Full text]
     
  800. Rational design and synthesis of highly potent pharmacological chaperones for treatment of N370S mutant Gaucher disease.
    G.N. Wang, G. Reinkensmeier, S.W. Zhang, J. Zhou, L.R. Zhang, L.H. Zhang, T.D. Butters and X.S. Ye (2009) J. Med. Chem., 52, 3146-3149. [Full text]
     
  801. Doubly carbon-branched pentoses: synthesis of both enantiomers of 2,4-di-C-methyl arabinose and 2-deoxy-2,4-di-C-methyl arabinose using only acetonide protection.
    K.V. Booth, S.F. Jenkinson, D. Best, F.F. Nieto, R.J. Estevez, M.R. Wormald, A.C. Weymouth-Wilson and G.W.J. Fleet (2009) Tetrahedron Letters, 50, 5088-5093. [Full text]
     
  802. Conservation of hydrophobicity within viral envelope glycoproteins reveals a putative hepatitis C virus fusion peptide.
    A. Taylor, J.M. O'Leary, S. Pollock and N. Zitzmann (2009) Protein Pept. Lett., 16, 815-822. [Full text]
     
  803. Qualitative and quantitative comparison of N-glycans between pig endothelial and islet cells by high-performance liquid chromatography and mass spectrometry-based strategy.
    Y.G. Kim, G.C. Gil, K.S. Jang, S. Lee, H.I. Kim, J.S. Kim, J. Chung, C.G. Park, D.J. Harvey and B.G. Kim (2009) J. Mass Spectrom., 44, 1087-1104. [Full text]
     
  804. A human embryonic kidney 293T cell line mutated at the Golgi alpha-mannosidase II locus.
    M. Crispin, V.T. Chang, D.J. Harvey, R.A. Dwek, E.J. Evans, D.I. Stuart, E.Y. Jones, J.M. Lord, R.A. Spooner and S.J. Davis (2009) J. Biol. Chem., 284, 21684-21695. [Full text]
     
  805. Unusual molecular architecture of the Machupo virus attachment glycoprotein.
    T.A. Bowden, M. Crispin, S.C. Graham, D.J. Harvey, J.M. Grimes, E.Y. Jones and D.I. Stuart (2009) J. Virol., 83, 8259-8265. [Full text] [Supplementary data]
     
  806. Proposal for a standard system for drawing structural diagrams of N- and O-linked carbohydrates and related compounds.
    D.J. Harvey, A.H. Merry, L. Royle, M.P. Campbell, R.A. Dwek and P.M. Rudd (2009) Proteomics, 9, 3796-3801. [Full text]
     
  807. Quality control of glycoproteins bearing truncated glycans in an ALG9-defective (CDG-IL) patient.
    W. Vleugels, L. Keldermans, J. Jaeken, T.D. Butters, J.C. Michalski, G. Matthijs and F. Foulquier (2009) Glycobiology, 19, 910-917. [Full text]
     
  808. Proteomic analysis of cells in the early stages of Herpes Simplex Virus Type-1 infection reveals widespread changes in the host cell proteome.
    R. Antrobus, K. Grant, B. Gangadharan, D. Chittenden, R.D. Everett, N. Zitzmann and C. Boutell (2009) Proteomics, 9, 3913-3927. [Full text] [Supplementary data]
     
  809. The three-dimensional structure of a hepatitis C virus p7 ion channel by electron microscopy.
    P. Luik, C. Chew, J. Aittoniemi, J. Chang, P. Wentworth Jr, R.A. Dwek, P.C. Biggin, C. Vénien-Bryan and N. Zitzmann (2009) Proc. Natl. Acad. Sci. USA, 106, 12712-12716. [Full text] [Supplementary data]
     
  810. Mechanism for the hydrolysis of a sulfur-sulfur bond based on the crystal structure of the thiosulfohydrolase SoxB.
    V. Sauve, P. Roversi, K.J. Leath, E.F. Garman, R. Antrobus, S.M. Lea and B.C. Berks (2009) J. Biol. Chem., 284, 21707-21718. [Full text] [Supplementary data]
     
  811. Proteomic analysis of integrin alphaIIbbeta3 outside-in signalling reveals Src-kinase-independent phosphorylation of Dok-1 and Dok-3 leading to SHIP-1 interactions.
    Y.A. Senis, R. Antrobus, S. Severin, A.F. Parguińa, I. Rosa, N. Zitzmann, S.P. Watson and Á. García (2009) J. Thromb. Haemost., 7, 1718-1726. [Full text] [Supplementary data]
     
  812. The hepatitis C virus E2p7 localization and topology in a recombinant system.
    C.I. Popescu, A.S. Grigorescu, R.A. Dwek and N. Zitzmann (2009) Rom. J. Biochem., 46, 149-163. [Full text]
     
  813. Identification of high-mannose and multiantennary complex-type N-linked glycans containing a-galactose epitopes from Nurse shark IgM heavy chain.
    D.J. Harvey, M. Crispin, B.E. Moffatt, S.L. Smith, R.B. Sim, P.M. Rudd and R.A. Dwek (2009) Glycoconj. J., 26, 1055-1064. [Full text]
     
  814. Novel mannosidase inhibitors probe glycoprotein degradation pathways in cells.
    T.D. Butters, D.S. Alonzi, N.V. Kukushkin, Y. Ren and Y. Blériot (2009) Glycoconj. J., 26, 1109-1116. [Full text]
     
  815. Soluble CD36 ectodomain binds negatively charged diacylglycerol ligands and acts as a co-receptor for TLR2.
    M.J. Jimenez-Dalmaroni, N. Xiao, A.L. Corper, P. Verdino, G.D. Ainge, D.S. Larsen, G.F. Painter, P.M. Rudd, R.A. Dwek, K. Hoebe, B. Beutler and I.A. Wilson (2009) PLoS One, 4, e7411. [Full text]
     
  816. Mass spectrometric analysis of the glycosphingolipid-derived glycans from miniature pig endothelial cells and islets: identification of NeuGc epitope in pig islets.
    Y.G. Kim, D.J. Harvey, Y.H. Yang, C.G. Park and B.G. Kim (2009) J. Mass Spectrom., 44, 1489-1499. [Full text]
     
  817. Oxidative stress in NPC1 deficient cells: Protective effect of allopregnanolone.
    S. Zampieri, S.H. Mellon, T.D. Butters, M. Nevyjel, D.F. Covey, B. Bembi and A. Dardis (2009) J. Cell. Mol. Med., 13, 3786-3796. [Full text]
     
  818. In-gel enzymatic release of N-glycans.
    D.J. Harvey (2009) in "The Protein Protocols Handbook", 3rd edition, pp.1357-1364 (Humana Press).
     
  819. Analysis of N-linked glycans by mass spectrometry.
    D.J. Harvey (2009) in "The Protein Protocols Handbook", 3rd edition, pp.1365-1380 (Humana Press).

    2010 - Top-Bottom

  820. Hepatitis B virus requires intact caveolin-1 function for productive infection in HepaRG cells.
    A. Macovei, C. Radulescu, C. Lazar, S.M. Petrescu, D. Durantel, R.A. Dwek, N. Zitzmann and N. Branza-Nichita (2010) J. Virology, 84, 243-253. [Full text]
     
  821. Analysis of CD161 expression on human CD8+ T cells defines a functional subset with tissue-homing properties.
    E. Billberbeck, Y. Kang, L. Walker, H. Lockstone, S. Grafmueller, V. Fleming, J. Flint, C.B. Willberg, B. Bengsch, B. Siegel, N. Ramamurthy, N. Zitzmann, E.J. Barnes, J. Thevanayagam, A. Bhagwanani, A. Leslie, Y.H. Oo, S. Kollnberger, P. Bowness, O. Dorgnitz, D.H. Adams, H.E. Blum, R. Thimme and P. Klenerman (2010) Proc. Natl. Acad. Sci. USA., 107, 3006-3011. [Full text] [Supplementary data]
     
  822. Activation state and intracellular trafficking contribute to the repertoire of endogenous glycosphingolipids presented by CD1d.
    K. Muindi, M. Cernadas, G.F.M. Watts, L. Royle, D.C.A. Neville, R.A. Dwek, G.S. Besra, P.M. Rudd, T.D. Butters and M.B. Brenner (2010) Proc. Natl. Acad. Sci. USA., 107, 3052-3057. [Full text] [Supplementary data]
     
  823. Identification of N-glycans from Ebola virus glycoproteins by matrix-assisted laser desorption/ionisation time-of-flight and negative ion electrospray tandem mass spectrometry.
    G. Ritchie, D.J. Harvey, U. Stroeher, F. Feldmann, H. Feldmann, V. Wahl-Jensen, L. Royle, R.A. Dwek and P.M. Rudd (2010) Rapid Commun. Mass Spectrom., 24, 571-585. [Full text]
     
  824. Identification of N-linked carbohydrates from severe acute respiratory syndrome (SARS) spike glycoprotein.
    G. Ritchie, D.J. Harvey, F. Feldmann, U. Stroeher, H. Feldmann, L. Royle, R.A. Dwek and P.M. Rudd (2010) Virology, 399, 257-269. [Full text]
     
  825. Chemical and enzymatic N-glycan release comparison for N-glycan profiling of monoclonal antibodies expressed in plants.
    A. Triguero, G. Cabrera, L. Royle, D.J. Harvey, P.M. Rudd, R.A. Dwek, M. Bardor, P. Lerouge and J.A. Cremata (2010) Anal. Biochem., 400, 173-183. [Full text]
     
  826. Glycosylation of liver acute-phase proteins in pancreatic cancer and chronic pancreatitis.
    A. Sarrats, R. Saldova, E. Pla, E. Fort, D.J. Harvey, W.B. Struwe, R. de Llorens, P.M. Rudd and R. Peracaula (2010) Proteomics Clin. Appl., 4, 432-448. [Full text]
     
  827. Fragmentation of negative ions from N-linked carbohydrates, Part 4. Fragmentation of complex glycans lacking substitution on the 6-antenna.
    D.J. Harvey, J. Jaeken, M. Butler, A.J. Armitage, P.M. Rudd and R.A. Dwek (2010) J. Mass Spectrom., 45, 528-535. [Full text]
     
  828. Lysosomal storage of oligosaccharide and glycosphingolipid in imino sugar treated cells.
    S.D. Boomkamp, J.S.S. Rountree, D.C.A. Neville, R.A. Dwek, G.W.J. Fleet and T.D. Butters (2010) Glycoconj. J., 27, 297-308. [Full text]
     
  829. Testing temperature induced proteomic changes in the plant associated bacterium Pseudomonas fluorescens SBW25.
    C.G. Knight, X.X. Zhang, A. Gunn, T. Brenner, R.W. Jackson, S.R. Giddens, S. Prabhakar, N. Zitzmann and P.B. Rainey (2010) Environ. Microbiol. Rep., 2. 396-402. [Full text] [Supplementary data] [Supplementary data table]
     
  830. Dimeric architecture of the hendra virus attachment glycoprotein: evidence for a conserved mode of assembly.
    T.A. Bowden, M. Crispin, D.J. Harvey, E.Y. Jones and D.I. Stuart (2010) J. Virol., 84, 6208-6217. [Full text]
     
  831. Carbohydrate analysis by ESI and MALDI.
    D.J. Harvey (2010) in "Electrospray and MALDI Mass Spectrometry: Fundamentals, Instrumentation, Practicalities, and Biological Applications", pp.723-769, ed. R.B. Cole (John Wiley and Sons Inc, USA). [Full text]
     
  832. Synthesis and solution phase conformation of the RG1 fragment of the plant polysaccharide pectin reveals a modification-modulated assembly mechanism.
    E.M. Scanlan, M.M. Mackeen, M.R. Wormald and B.G. Davis (2010) J. Am. Chem. Soc., 132, 7238-7239. [Full text] [Supplementary data]
     
  833. Polysaccharide mimicry of the epitope of the broadly neutralising anti-HIV antibody, 2G12, induces enhanced antibody responses to self oligomannose glycans.
    D.C. Dunlop, C. Bonomelli, F. Mansab, S. Vasiljevic, K.J. Doores, M.R. Wormald, A.S. Palma, T. Feizi, D.J. Harvey, R.A. Dwek, M. Crispin and C.N. Scanlan (2010) Glycobiology, 20, 812-823. [Full text]
     
  834. Uptake and trafficking of liposomes to the endoplasmic reticulum.
    S. Pollock, R. Antrobus, L. Newton, B. Kampa, J. Rossa, S. Latham, N. Branza-Nichita, R.A. Dwek and N. Zitzmann (2010) FASEB J., 24, 1866-1878. [Full text] [Supplementary data]
     
  835. Targeting a host process as an antiviral approach against dengue virus.
    A.C. Sayce, J.L. Miller and N. Zitzmann (2010) Trends Microbiol., 18, 323-330. [Full text]
     
  836. Cystic fibrosis and diabetes: isoLAB and isoDAB, enantiomeric carbon-branched pyrrolidine iminosugars.
    D. Best, S.F. Jenkinson, A.W. Saville, D.S. Alonzi, M.R. Wormald, T.D. Butters, C. Norez, F. Becq, Y. Blériot, I. Adachi, A. Kato and G.W.J. Fleet (2010) Tetrahedron Letters, 51, 4170-4174. [Full text]
     
  837. Letter - Identification of by-products formed during the release of N-glycans with protein N-glycosidase F in the presence of dithiothreitol.
    D.J. Harvey and P.M. Rudd (2010) J. Mass Spectrom., 45, 815-819. [Full text]
     
  838. The N-glycosylation of classical swine fever virus E2 glycoprotein extracellular domain expressed in the milk of goat.
    R. Montesino, J. Gil, L.J. González, Y. Zamora, L. Royle, P.M. Rudd, R.A. Dwek, D.J. Harvey and J.A. Cremata (2010) Arch. Biochem. Biophys., 500, 169-180. [Full text]
     
  839. Restricted ketogenic diet enhances the therapeutic action of N-butyldeoxynojirimycin towards brain GM2 accumulation in adult Sandhoff disease mice.
    C.A. Denny, K.A. Heinecke, Y.P. Kim, R.C. Baek, K.S. Loh, T.D. Butters, R.T. Bronson, F.M. Platt and T.N. Seyfried (2010) J. Neurochem., 113, 1525-1535. [Full text]
     
  840. Transcriptome sequencing, microarray, and proteomic analyses reveal cellular and metabolic impact of hepatitis C virus infection in vitro.
    S.D. Woodhouse, R. Narayan, S. Latham, S. Lee, R. Antrobus, B. Gangadharan, S. Luo, G.P. Schroth, P. Klenerman and N. Zitzmann (2010) Hepatology, 52, 443-453. [Full text] [Supplementary data]
     
  841. Envelope glycans of immunodeficiency virions are almost entirely oligomannose antigens.
    K.J. Doores, C. Bonomelli, D.J. Harvey, S. Vasiljevic, R.A. Dwek, D.R. Burton, M. Crispin and C.N. Scanlan (2010) Proc. Natl. Acad. Sci. USA., 107, 13800-13805. [Full text] [Supplementary data]
     
  842. A 'non-self' sugar mimic of the HIV 'glycan shield' shows enhanced antigenicity.
    K.J. Doores, Z. Fulton, V. Hong, M.K. Patel, C.N. Scanlan, M.R. Wormald, M.G. Finn, D.R. Burton, I.A. Wilson and B.G. Davis (2010) Proc. Natl. Acad. Sci. USA, 107, 17107-17112. [Full text] [Supplementary data]
     
  843. Polyunsaturated liposomes are antiviral against hepatitis B and C viruses and HIV by decreasing cholesterol levels in infected cells.
    S. Pollock, N. Branza-Nichita, A. Böhmer, C. Radulescu, R.A. Dwek and N. Zitzmann (2010) Proc. Natl. Acad. Sci. USA, 107, 17176-17181. [Full text] [Supplementary data]
     
  844. Expression system-dependent modulation of HIV-1 envelope glycoprotein antigenicity and immunogenicity.
    L. Kong, N.C. Sheppard, G.B.E. Stewart-Jones, C.L. Robson, H. Chen, X. Xu, G. Krashias, C. Bonomelli, C.N. Scanlan, P.D. Kwong, S.A. Jeffs, I.M. Jones and Q.J. Sattentau (2010) J. Mol. Biol., 403, 131-147. [Full text] [Supplementary data]
     
  845. Shared paramyxoviral glycoprotein architecture is adapted for diverse attachment strategies.
    T.A. Bowden, M. Crispin, E.Y. Jones and D.I. Stuart (2010) Biochem. Soc. Trans., 38, 1349-1355. [Full text]
     
  846. Characterization of simple isomeric oligosaccharides and the rapid separation of glycan mixtures by ion mobility mass spectrometry.
    J.P. Williams, M. Grabenauer, R.J. Holland, C.J. Carpenter, M.R. Wormald, K. Giles, D.J. Harvey, R.H. Bateman, J.H. Scrivens and M.T. Bowers (2010) Int. J. Mass Spectrom., 298, 119-127. [Full text]
     
  847. Multifaceted approaches including neoglycolipid oligosaccharide microarrays to ligand discovery for malectin.
    A.S. Palma, Y. Liu, C. Muhle-Goll, T.D. Butters, Y. Zhang, R. Childs, W. Chai and T. Feizi (2010) in "Glycomics", Methods in Enzymology, 478, pp. 265-286, ed. M. Fukuda (Academic Press Inc). [Full text]
     
  848. Synthesis of 2-acetamido-1,2-dideoxy-D-galacto-nojirimycin (DGJNAc) from D-glucuronolactone: the first sub-micromolar inhibitor of alpha-N-acetylgalactosaminidases.
    D. Best, P. Chairatana, A.F.G. Glawar, E. Crabtree, T.D. Butters, F.X. Wilson, C.Y. Yu, W.B. Wang, Y.M. Jia, I. Adachi, A. Kato and G.W.J. Fleet (2010) Tetrahedron Letters, 51, 2222-2224. [Full text]

    2011 - Top-Bottom

  849. 4-C-Me-DAB and 4-C-Me-LAB - enantiomeric alkyl-branched pyrrolidine iminosugars - are specific and potent a-glucosidase inhibitors; acetone as the sole protecting group.
    F.P. da Cruz, S. Newberry, S.F. Jenkinson, M.R. Wormald, T.D. Butters, D.S. Alonzi, S. Nakagawa, F. Becq, C. Norez, R.J. Nash, A. Kato and G.W.J. Fleet (2011) Tetrahedron Letters, 52, 219-223. [Full text]
     
  850. Solutions to the glycosylation problem for low- and high-throughput structural glycoproteomics.
    S.J. Davis and M. Crispin (2011) in "Functional and Structural Proteomics of Glycoproteins", pp.127-158, ed. R. Owens and J. Nettleship (Springer). [Full text]
     
  851. Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: An update covering the period 2005-2006.
    D.J. Harvey (2011) Mass Spectrom. Rev., 30, 1-100. [Full text]
     
  852. Review - Urinary glycan markers for disease.
    D.S. Alonzi, Y.H. Su and T.D. Butters (2011) Biochem. Soc. Trans., 39, 393-398. [Full text]
     
  853. Synthesis of N-alkylated noeurostegines and evaluation of their potential as treatment for Gaucher's disease.
    T.S. Rasmussen, S.A. Allman, G. Twigg, T.D. Butters and H.H. Jensen (2011) Bioorg. Med. Chem. Lett., 21, 1519-1522. [Full text]
     
  854. Enantiomeric 2-acetamido-1,4-dideoxy-1,4-iminoribitols as potential pyrrolidine hexosaminidase inhibitors.
    J.S.S. Rountree, T.D. Butters, R.A. Dwek and G.W.J. Fleet (2011) C. R. Chimie, 14, 126-133. [Full text]
     
  855. Ion mobility mass spectrometry for extracting spectra of N-glycans directly from incubation mixtures following glycan release: Application to glycans from engineered glycoforms of intact, folded HIV gp120.
    D.J. Harvey, F. Sobott, M. Crispin, A. Wrobel, C. Bonomelli, S. Vasiljevic, C.N. Scanlan, C. Scarff, K. Thalassinos and J.H. Scrivens, (2011) J. Am. Soc. Mass Spectrom., 22, 568-581. [Full text]
     
  856. Erythropoietin produced in a human cell line (Dynepo®) has significant differences in glycosylation compared with erythropoietins produced in CHO cell lines.
    Z. Shahrokh, L. Royle, R. Saldova, J. Bones, J.L. Abrahams, N. Artemenko, S. Flatman, M. Davies, A. Baycroft, S. Sehgal, M.W. Heartlein, D.J. Harvey and P.M. Rudd (2011) Molecular Pharmaceutics, 8, 286-296. [Full text]
     
  857. Tuning the cavity of cyclodextrins: altered sugar adaptors in protein pores.
    W.W. Li, T.D.W. Claridge, Q. Li, M.R. Wormald, B.G. Davis and H. Bayley (2011) J. Am. Chem. Soc., 133, 1987-2001. [Full text] [Supplementary data]
     
  858. Novel glycan biomarkers for the detection of lung cancer.
    J.N. Arnold, R. Saldova, M.C. Galligan, T.B. Murphy, Y. Mimura-Kimura, J.E. Telford, A.K. Godwin and P.M. Rudd (2011) J. Proteome Res., 10, 1755-1764. [Full text] [Supplementary data]
     
  859. New approaches for biomarker discovery: The search for liver fibrosis markers in hepatitis C patients.
    B. Gangadharan, R. Antrobus, D. Chittenden, J. Rossa, M. Bapat, P. Klenerman, E. Barnes, R.A. Dwek and N. Zitzmann (2011) J. Proteome Res., 10, 2643-2650. [Full text] [Supplementary data]
     
  860. Combination of a-glucosidase inhibitor and ribavirin for the treatment of dengue virus infection in vitro and in vivo.
    J. Chang, W. Schul, T.D. Butters, A. Yip, B. Liu, A. Goh, S.B. Lakshminarayana, D.S. Alonzi, G. Reinkensmeier, X. Pan, X. Qu, J.M. Weidner, L. Wang, W. Yu, N. Borune, M.A. Kinch, J.E. Rayahin, R. Moriarty, X. Xu, P.Y. Shi, J.T. Guo and T.M. Block (2011) Antiviral Res., 89, 26-34. [Full text]
     
  861. Inhibitors of endoplasmic reticulum alpha-glucosidases potently suppress hepatitis C virus virion assembly and release.
    X. Qu, X. Pan, J. Weidner, W. Yu, D.S. Alonzi, X. Xu, T.D. Butters, T. Block, J.T. Guo and J. Chang (2011) Antimicrobial Agents and Chemotherapy, 55, 1036-1044. [Full text]
     
  862. Adduction of cholesterol 5,6-secosterol aldehyde to membrane-bound myelin basic protein exposes an immunodominant epitope.
    N.K. Cygan, J.C. Scheinost, T.D. Butters and P. Wentworth Jr (2011) Biochemistry, 50, 2092-2100. [Full text] [Supplementary data]
     
  863. Polyhydroxylated bicyclic isoureas and guanidines are potent glucocerebrosidase inhibitors and nanomolar enzyme activity enhancers in Gaucher cells.
    A. Trapero, I. Alfonso, T.D. Butters and A. Llebaria (2011) J. Am. Chem. Soc., 133, 5474-5484. [Full text] [Supplementary data]
     
  864. Therapeutic targets for inhibitors of glycosylation.
    D.S. Alonzi and T.D. Butters (2011) Chimia (Aarau), 65, 35-39. [Full text]
     
  865. EUROCarbDB: An open-access platform for glycoinformatics.
    C.W. von der Lieth, A.A. Freire, D. Blank, M.P. Campbell, A. Ceroni, D.D. Damerell, A. Dell, R.A. Dwek, B. Ernst, M. Frank, H. Geyer, R. Geyer, M.J. Harrison, K. Henrick, S. Herget, W.E. Hull, J. Ionides, H.J. Joshi, J.P. Kamerling, B.R. Leeflang, T. Lütteke, M. Lundborg, K. Maass, A. Merry, R. Ranzinger, J. Rosen, L. Royle, P.M. Rudd, S. Schloissnig, R. Stenutz, W.F. Vrancken, G. Widmalm and S.M. Haslam (2011) Glycobiology, 21, 493-502. [Full text]
     
  866. Derivatization of carbohydrates for analysis by chromatography, electrophoresis and mass spectrometry.
    D.J. Harvey (2011) J. Chromatogr. B, 879, 1196-1225. [Full text]
     
  867. Unique N-glycan moieties in 66-kDa glycoprotein of the cell-wall glycoprotein of the red microalga Porphyridium sp.
    O. Levy-Ontman, S. Arad, D.J. Harvey and Y. Tekoah (2011) J. Biol. Chem., 286, 21340-21352. [Full text] [Supplementary data]
     
  868. Thiazolides as novel antiviral agents. 1. Inhibition of hepatitis B virus replication.
    A.V. Stachulski, C. Pidathala, E.C. Row, R. Sharma, N.G. Berry, M. Iqbal, J. Bentley, S.A. Allman, G. Edwards, A. Helm, J. Hellier, B.E. Korba, J.E. Semple and J.F. Rossignol (2011) J. Med. Chem., 54, 4119-4132. [Full text]
     
  869. The Biochemical Basis | Structure and biosynthesis of glycoprotein carbohydrates.
    M. Crispin, C.N. Scanlan and T.A. Bowden (2011) in "Comprehensive Biotechnology", 2nd edition, 1, pp. 73-90, ed. M. Moo-Young (Elsevier). [Full text]
     
  870. Systems Biology | Glycomics.
    E.F.J. Cosgrave, W.B. Struwe, J.J. Kattla, M.P. Campbell, M.R. Wormald and P.M. Rudd (2011) in "Comprehensive Biotechnology", 2nd edition, 1, pp. 427-446, ed. M. Moo-Young (Elsevier). [Full text]
     
  871. Selection of the biological activity of DNJ neoglycoconjugates through click length variation of the side chain.
    N. Ardes-Guisot, D.S. Alonzi, G. Reinkensmeier, T.D. Butters, C. Norez, F. Becq, Y. Shimada, S. Nakagawa, A. Kato, Y. Blériot, M. Sollogoub and B. Vauzeilles (2011) Org. Biomol. Chem., 9, 5373-5388. [Full text]
     
  872. Fragmentation of negative ions from N-linked carbohydrates: Part 5: Anionic N-linked glycans.
    D.J. Harvey and P.M. Rudd (2011) Int. J. Mass Spectrom., 305, 120-130. [Full text]
     
  873. Use of the a-mannosidase I inhibitor kifunensine allows the crystallization of apo CTLA-4 homodimer produced in long-term cultures of chinese hamster ovary cells.
    C. Yu, M. Crispin, A.F. Sonnen, D.J. Harvey, V.T. Chang, E.J. Evans, C.N. Scanlan, D.I. Stuart, R.J.C. Gilbert and S.J. Davis (2011) Acta Cryst., F67, 785-789. [Full text] [Supplementary data]
     
  874. The influence of different lipid environments on the structure and function of the hepatitis C virus p7 ion channel protein.
    T. Whitfield, A.J. Miles, J.C. Scheinost, J. Offer, P. Wentworth Jr, R.A. Dwek, B.A. Wallace, P.C. Biggin and N. Zitzmann (2011) Mol. Membr. Biol., 28, 254-264. [Full text]
     
  875. Demonstration that endoplasmic reticulum-associated degradation of glycoproteins can occur downstream of processing by endomannosidase.
    N.V. Kukushkin, D.S. Alonzi, R.A. Dwek and T.D. Butters (2011) Biochem. J., 438, 133-142. [Full text]
     
  876. Synthesis and a-Glucosidase II inhibitory activity of valienamine pseudodisaccharides relevant to N-glycan biosynthesis.
    I. Cumpstey, C. Ramstadius, K. Eszter Borbas, D.S. Alonzi and T.D. Butters (2011) Bioorg. Med. Chem. Lett., 21, 5219-5223. [Full text] [Supplementary data]
     
  877. The glycan shield of HIV is predominantly oligomannose independently of production system or viral clade.
    C. Bonomelli, K.J. Doores, D.C. Dunlop, V. Thaney, R.A. Dwek, D.R. Burton, M. Crispin and C.N. Scanlan (2011) PLoS One, 6, e23521. [Full text]
     
  878. Amine-linked diglycosides: Synthesis facilitated by the enhanced reactivity of allylic electrophiles, and glycosidase inhibition assays.
    I. Cumpstey, J. Frigell, E. Pershagen, T. Akhtar, E. Moreno-Clavijo, I. Robina, D.S. Alonzi and T.D. Butters (2011) Beilstein J. Org. Chem., 7, 1115-1123. [Full text] [Supplementary data]
     
  879. Method for milk oligosaccharide profiling by 2-aminobenzamide labeling and hydrophilic interaction chromatography.
    K. Marińo, J.A. Lane, J.L. Abrahams, W.B. Struwe, D.J. Harvey, M. Marotta, R.M. Hickey and P.M. Rudd (2011) Glycobiology, 21, 1317-1330. [Full text]
     
  880. Measurement of type I interferon production.
    R.E. Seeds and J.L. Miller (2011) in "Current Protocols in Immunology, Supplement 92", pp. 14.21.1-14.21.11 (John Wiley). [Full text]
     
  881. Two dimensional gel electrophoresis using narrow pH 3-5.6 immobilised pH gradient strips identifies potential novel disease biomarkers in plasma or serum.
    B. Gangadharan and N. Zitzmann (2011) Nature Protocol Exchange, doi:10.1038/protex.2011.261. [Full text] [Supplementary data]
     
  882. Cholesterol depletion of hepatoma cells impairs Hepatitis B virus envelopment by altering the topology of the large envelope protein.
    C. Dorobantu, A. Macovei, C. Lazar, R.A. Dwek, N. Zitzmann and N. Branza-Nichita (2011) J. Virol., 85, 13373-13383. [Full text]
     
  883. 5-AZA-dC induced demethylation influences N-glycosylation of secreted glycoproteins in ovarian cancer.
    R. Saldova, E. Dempsey, M. Perez-Garay, K. Marino, J.A. Watson, A. Blanco-Fernández, W.B. Struwe, D.J. Harvey, S.F. Madden, R. Peracaula, A.H. McCann and P.M. Rudd (2011) Epigenetics, 2011, 6, 1362-1372. [Full text]
     
  884. Viewpoint - UniCarbKB: putting the pieces together for glycomics research.
    M.P. Campbell, C.A. Hayes, W.B. Struwe, M.R. Wilkins, K.F. Aoki-Kinoshita, D.J. Harvey, P.M. Rudd, D. Kolarich, F. Lisacek, N.G. Karlsson and N.H. Packer (2011) Proteomics, 11, 4117-4121. [Full text]
     
  885. Viewpoint - Symbol nomenclature for representing glycan structures: Extension to cover different carbohydrate types.
    D.J. Harvey, A.H. Merry, L. Royle, M.P. Campbell and P.M. Rudd (2011) Proteomics, 11, 4291-4295. [Full text]
     
  886. Endoplasmic reticulum-associated degradation (ERAD) and free oligosaccharide generation in Saccharomyces cerevisiae.
    I. Chantret, V.P. Kodali, C. Lahmouich, D.J. Harvey and S.E.H. Moore (2011) J. Biol. Chem., 286, 41786-41800. [Full text]
     
  887. Amphiphilic 1-deoxynojirimycin derivatives through click strategies for chemical chaperoning in N370S Gaucher cells.
    J.D. Diot, I.G. Moreno, G. Twigg, C.O. Mellet, K. Haupt, T.D. Butters, J. Kovensky and S.G. Gouin (2011) J. Org. Chem., 76, 7757-7768. [Full text] [Supplementary data]
     
  888. A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield.
    R. Pejchal, K.J. Doores, L.M. Walker, R. Khayat, P.S. Huang, S.K. Wang, R.L. Stanfield, J.P. Julien, A. Ramos, M. Crispin, R. Depetris, U. Katpally, A. Marozsan, A. Cupo, S. Maloveste, Y. Liu, R. McBride, Y. Ito, R.W. Sanders, C. Ogohara, J.C. Paulson, T. Feizi, C.N. Scanlan, C.H. Wong, J.P. Moore, W.C. Olson, A.B. Ward, P. Poignard, W.R. Schief, D.R. Burton and I.A. Wilson (2011) Science, 334, 1097-1103. [Full text]
     
  889. Differential N-glycosylation of a monoclonal antibody expressed in tobacco leaves with and without Endoplasmic Reticulum retention signal apparently induces similar in vivo stability in mice.
    A. Triguero, G. Cabrera, M. Rodríguez, J. Soto, Y. Zamora, M. Pérez, M.R. Wormald and J.A. Cremata (2011) Plant Biotechnol. J., 9, 1120-1130. [Full text]
     
  890. High throughput isolation and glycosylation analysis of IgG - variability and heritability of the IgG glycome in three isolated human populations.
    M. Pucic, A. Knezevic, J. Vidic, B. Adamczyk, M. Novokmet, O. Polasek, O. Gornik, S. Supraha-Goreta, M.R. Wormald, I. Redzic, H. Campbell, A. Wright, N.D. Hastie, J.F. Wilson, I. Rudan, M. Wuhrer, P.M. Rudd, D. Josic and G. Lauc (2011) Mol. Cell. Proteomics, 10, M111.010090, p.1-15. [Full text] [Supplementary data]
     
  891. Thiazolides as novel antiviral agents. 2. Inhibition of Hepatitis C virus replication.
    A.V. Stachulski, C. Pidathala, E.C. Row, R. Sharma, N.G. Berry, A.S. Lawrenson, S.L. Moores, M. Iqbal, J. Bentley, S.A. Allman, G. Edwards, A. Helm, J. Hellier, B.E. Korba, J.E. Semple and J.F. Rossignol (2011) J. Med. Chem., 54, 8670-8680. [Full text] [Supplementary data]
     
  892. Baruch Blumberg - The Oxford-Romanain connection.
    R.A. Dwek (2011) Rom. J. Biochem., 48, 5-12. [Full text]

    2012 - Top-Bottom

  893. Towards a stable noeuromycin analog with a d-manno configuration: Synthesis and glycosidase inhibition of d-manno-like tri- and tetrahydroxylated azepanes.
    J. Deschamp, M. Mondon, S. Nakagawa, A. Kato, D.S. Alonzi, T.D. Butters, Y. Zhang, M. Sollogoub and Y. Blériot (2012) Bioorg. Med. Chem., 20, 641-649. [Full text]
     
  894. Structural and mechanistic insight into N-glycan processing by endo-alpha-mannosidase.
    A.J. Thompson, R.J. Williams, Z. Hakki, D.S. Alonzi, T. Wennekes, T.M. Gloster, K. Songsrirote, J.E. Thomas-Oates, T.M. Wrodnigg, J. Spreitz, A.E. Stütz, T.D. Butters, S.J. Williams and G.J. Davies (2012) Proc. Natl. Acad. Sci. USA, 109, 781-786. [Full text] [Supplementary data] [Movie]
     
  895. Production and fragmentation of negative ions from neutral N-linked carbohydrates ionized by matrix-assisted laser desorption/ionization.
    P. Domann, D.I.R. Spencer and D.J. Harvey (2012) Rapid Commun. Mass Spectrom., 26, 469-479. [Full text]
     
  896. Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: An update covering the period 2007-2008.
    D.J. Harvey (2012) Mass Spectrom. Rev., 31, 183-311. [Full text]
     
  897. Hydrophilic interaction liquid chromatography of anthranilic acid-labelled oligosaccharides with a 4-aminobenzoic acid ethyl ester-labelled dextran hydrolysate internal standard.
    D.C.A. Neville, D.S. Alonzi, T.D. Butters (2012) J. Chromatogr. A, 1233, 66-70. [Full text]
     
  898. Modeling of the N-glycosylated transferrin receptor suggests how transferrin binding can occur within the surface coat of Trypanosoma brucei.
    A. Mehlert, M.R. Wormald and M.A.J. Ferguson (2012) PLoS Pathogens, 8, e1002618. [Full text]
     
  899. Synthesis of N-substituted e-hexonolactams as pharmacological chaperones for the treatment of N370S mutant Gaucher disease.
    G.N. Wang, G. Twigg, T.D. Butters, S. Zhang, L. Zhang, L.H. Zhang and X.S. Ye (2012) Org. Biomol. Chem., 10, 2923-2927. [Full text]
     
  900. Eight stereoisomers of homonojirimycin from D-mannose.
    G.M.J. Lenagh-Snow, S.F. Jenkinson, S.J. Newberry, A. Kato, S. Nakagawa, I. Adachi, M.R. Wormald, A. Yoshihara, K. Morimoto, K. Akimitsu, K. Izumori and G.W.J. Fleet (2012) Organic Letters, 14, 2050-2053. [Full text] [Supplementary data]
     
  901. An endoglycosidase with alternative glycan specificity allows broadened glycoprotein remodelling.
    J.J. Goodfellow, K. Baruah, K. Yamamoto, C. Bonomelli, B.A. Krishna, D.J. Harvey, M. Crispin, C.N. Scanlan and B.G. Davis (2012) J. Am. Chem. Soc., 134, 8030-8033. [Full text] [Supplementary data]
     
  902. Selective deactivation of serum IgG: a general strategy for the enhancement of monoclonal antibody receptor interactions.
    K. Baruah, T.A. Bowden, B.A. Krishna, R.A. Dwek, M. Crispin and C.N. Scanlan (2012) J. Mol. Biol., 420, 1-7. [Full text] [Supplementary data]
     
  903. Potent aminocyclitol glucocerebrosidase inhibitors are subnanomolar pharmacological chaperones for treating Gaucher disease.
    A. Trapero, P. González-Bulnes, T.D. Butters and A. Llebaria (2012) J. Med. Chem., 55, 4479-4488. [Full text] [Supplementary data]
     
  904. Discovery of novel biomarker candidates for liver fibrosis in hepatitis C patients: a preliminary study.
    B. Gangadharan, M. Bapat, J. Rossa, R. Antrobus, D. Chittenden, B. Kampa, E. Barnes, P. Klenerman, R.A. Dwek and N. Zitzmann (2012) PLoS One, 7, e39603. [Full text] [Supplementary data]
     
  905. Structural characterization of N-linked oligosaccharides on monoclonal antibody Nimotuzumab through process development.
    R. Montesino, L. Calvo, A. Vallin, P.M. Rudd, D.J. Harvey and J.A. Cremata (2012) Biologicals, 40, 288-298. [Full text]
     
  906. Fleetamine (3-O-a-D-glucopyranosyl-swainsonine): the synthesis of a hypothetical inhibitor of endo-a-mannosidase.
    T. Quach, S. Tsegay, A.J. Thompson, N.V. Kukushkin, D.S. Alonzi, T.D. Butters, G.J. Davies and S.J. Williams (2012) Tetrahedron: Asymmetry, 23, 992-997. [Full text]
     
  907. Synthesis from D-altrose of (5R,6R,7R,8S)-5,7-dihydroxy-8-hydroxymethylconidine and 2,4-dideoxy-2,4-imino-D-glucitol, azetidine analogues of swainsonine and 1,4-dideoxy-1,4-imino-D-mannitol.
    N. Araujo, S.F. Jenkinson, R.F. Martínez, A.F.G. Glawar, M.R. Wormald, T.D. Butters, S. Nakagawa, I. Adachi, A. Kato, A. Yoshihara, K. Akimitsu, K. Izumori and G.W.J. Fleet (2012) Organic Letters, 14, 4174-4177. [Full text] [Supplementary data]
     
  908. Scalable syntheses of both enantiomers of DNJNAc and DGJNAc from glucuronolactone: the effect of N-alkylation on hexosaminidase inhibition.
    A.F.G. Glawar, D. Best, B.J. Ayers, S. Miyauchi, S. Nakagawa, M. Aguilar-Moncayo, J.M. García Fernández, C. Ortiz Mellet, E.V. Crabtree, T.D. Butters, F.X. Wilson, A. Kato and G.W.J. Fleet (2012) Chem. Eur. J., 18, 9341-9359. [Full text] [Supplementary data]
     
  909. Restricted processing of glycans by endomannosidase in mammalian cells.
    N.V. Kukushkin, I.S. Easthope, D.S. Alonzi and T.D. Butters (2012) Glycobiology, 22, 1282-1288. [Full text] [Supplementary data]
     
  910. MALDI-MS/MS with traveling wave ion mobility for the structural analysis of N-Linked glycans.
    D.J. Harvey, C.A. Scarff, M. Crispin, C.N. Scanlan, C. Bonomelli and J.H. Scrivens (2012) J. Am. Soc. Mass Spectrom., 23, 1955-1966. [Full text] [Supplementary data]
     
  911. Chemical and structural analysis of an antibody folding intermediate trapped during glycan biosynthesis.
    T.A. Bowden, K. Baruah, C.H. Coles, D.J. Harvey, X. Yu, B.D. Song, D.I. Stuart, A.R. Aricescu, C.N. Scanlan, E.Y. Jones and M. Crispin (2012) J. Am. Chem. Soc., 134, 17554-17563. [Full text] [Supplementary data]
     
  912. Liposome mediated delivery of iminosugars enhances efficacy against dengue virus in vivo.
    J.L. Miller, R. Lachica, A.C. Sayce, J.P. Williams, M. Bapat, R.A. Dwek, P.R. Beatty, E. Harris and N. Zitzmann (2012) Antimicrobial Agents and Chemotherapy, 56, 6379-6386. [Full text] [Supplementary data]
     
  913. Perspectives - A blueprint for HIV vaccine discovery.
    D.R. Burton, R. Ahmed, D.H. Barouch, S.T. Butera, S. Crotty, A. Godzik, D.E. Kaufmann, M.J. McElrath, M.C. Nussenzweig, B. Pulendran, C.N. Scanlan, W.R. Schief, G. Silvestri, H. Streeck, B.D. Walker, L.M. Walker, A.B. Ward, I.A. Wilson and R. Wyatt (2012) Cell Host Microbe, 18, 396-407. [Full text]
     
  914. Macrophages from human pluripotent stem cells.
    S.A. Cowley, K.R. Karlsson, B. van Wilgenburg, G.C. Carter, C. Browne, J. Vowles, F.M. Estrada, A. Pelchen-Matthews, J.L. Miller, M.D. Moore and W. James (2012) in "Handbook of Macrophages: Life Cycle, Functions and Diseases", pp. 83-120, ed. R. Takahashi and H Kai (Nova Science Publishers, Inc., NY). [Full text]

    2013 - Top-Bottom

  915. Mass spectrometry of N-linked carbohydrates and glycoproteins.
    D.J. Harvey (2013) in "Encyclopedia of Biophysics", pp. 1405-1416, ed. G.C.K. Roberts (Springer). [Full text]
     
  916. An iminosugar with potent inhibition of dengue virus infection in vivo.
    S.T. Perry, M.D. Buck, E.M. Plummer, R.A. Penmasta, H. Batra, E.J. Stavale, K.L. Warfield, R.A. Dwek, T.D. Butters, D.S. Alonzi, S.M. Lada, K. King, B. Klose, U. Ramstedt and S. Shresta (2013) Antiviral Res., 98, 35-43. [Full text] [Supplementary data]
     
  917. Letter - Glucocorticosteroids as dengue therapeutics: resolving clinical observations with a primary human macrophage model.
    A.C. Sayce, J.L. Miller and N. Zitzmann (2013) Clin. Infect. Dis., 56, 901-903. [Full text]
     
  918. Dissecting the molecular mechanism of IVIg therapy: The interaction between serum IgG and DC-SIGN is independent of antibody glycoform or Fc domain.
    X. Yu, S. Vasiljevic, M. Crispin and C.N. Scanlan (2013) J. Mol. Biol., 425, 1253-1258. [Full text] [Supplementary data]
     
  919. 3-hydroxyazetidine carboxylic acids: non-proteinogenic amino acids for medicinal chemists.
    A.F.G. Glawar, S.F. Jenkinson, A.L. Thompson, S. Nakagawa, A. Kato, T.D. Butters and G.W.J. Fleet (2013) ChemMedChem, 8, 658-666. [Full text] [Supplementary data]
     
  920. Impact of immune complex size and glycosylation on IgG binding to human FcgammaRs.
    A. Lux, X. Yu, C.N. Scanlan and F. Nimmerjahn (2013) J. Immunol., 190, 4315-4323. [Full text] [Supplementary data]
     
  921. Ion mobility mass spectrometry of complex carbohydrates - collision cross sections of sodiated N-linked glycans.
    K. Pagel and D.J. Harvey (2013) Anal. Chem., 85, 5138-5145. [Full text] [Supplementary data]
     
  922. Natural variation in Fc glycosylation of HIV-specific antibodies impacts antiviral activity.
    M.E. Ackerman, M. Crispin, X. Yu, K. Baruah, A.W. Boesch, D.J. Harvey, A.S. Dugast, E.L. Heizen, A. Ercan, I. Choi, H. Streeck, P.A. Nigrovic, C. Bailey-Kellogg, C.N. Scanlan and G. Alter (2013) J. Clin. Invest., 123, 2183-2192. [Full text] [Supplementary data]
     
  923. Small molecule inhibitors of ER a-glucosidases are active against multiple hemorrhagic fever viruses.
    J. Chang, T.K. Warren, X. Zhao, T. Gill, F. Guo, L. Wang, M.A. Comunale, Y. Du, D.S. Alonzi, W. Yu, H. Ye, F. Liu, J.T. Guo, A. Mehta, A. Cuconati, T.D. Butters, S. Bavari, X. Xu and T.M. Block (2013) Antiviral Res., 98, 432-440. [Full text]
     
  924. Commentary - Therapeutic potential of deglycosylated antibodies.
    M. Crispin (2013) Proc. Natl. Acad. Sci. USA, 110, 10059-10060. [Full text]
     
  925. Glycoprotein misfolding in the endoplasmic reticulum: identification of released oligosaccharides reveals a second ER-associated degradation pathway for Golgi-retrieved proteins.
    D.S. Alonzi, N.V. Kukushkin, S.A. Allman, Z. Hakki, S.J. Williams, L. Pierce, R.A. Dwek and T.D. Butters (2013) Cell Mol. Life Sci., 70, 2799-2814. [Full text] [Supplementary data]
     
  926. Novel imino sugar a-glucosidase inhibitors as antiviral compounds.
    J.D. Howe, N. Smith, M.J. Lee, N. Ardes-Guisot, B. Vauzeilles, J. Désiré, A. Baron, Y. Blériot, M. Sollogoub, D.S. Alonzi and T.D. Butters (2013) Bioorg. Med. Chem., 21, 4831-4838. [Full text]
     
  927. Engineering hydrophobic protein–carbohydrate interactions to fine-tune monoclonal antibodies.
    X. Yu, K. Baruah, D.J. Harvey, S. Vasiljevic, D.S. Alonzi, B.D. Song, M.K. Higgins, T.A. Bowden, C.N. Scanlan and M. Crispin (2013) J. Am. Chem. Soc., 135, 9723-9732. [Full text] [Supplementary data]
     
  928. News and views - Antibodies expose multiple weaknesses in the glycan shield of HIV.
    M. Crispin and T.A. Bowden (2013) Nat. Struct. Mol. Biol., 20, 771-772. [Full text]
     
  929. The presence of outer arm fucose residues on the N-glycans of tissue inhibitor of metalloproteinases-1 reduces its activity.
    H.I. Kim, R. Saldova, J.H. Park, Y.H. Lee, D.J. Harvey, M.R. Wormald, K. Wynne, G. Elia, H.-J. Kim, P.M. Rudd and S.-T. Lee (2013) J. Proteome Res., 12, 3547-3560. [Full text] [Supplementary data]
     
  930. N-linked glycan structures of the human Fc gamma receptors produced in NS0 cells.
    E.F.J. Cosgrave, W.B. Struwe, J.M. Hayes, D.J. Harvey, M.R. Wormald and P.M. Rudd (2013) J. Proteome Res., 12, 3721-3737. [Full text]
     
  931. C-Branched iminosugars: a-glucosidase inhibition by enantiomers of isoDMDP, isoDGDP, and isoDAB-l-isoDMDP compared to Miglitol and Miglustat.
    S.F. Jenkinson, D. Best, A.W. Saville, J. Mui, R.F. Martínez, S. Nakagawa, T. Kunimatsu, D.S. Alonzi, T.D. Butters, C. Norez, F. Becq, Y. Blériot, F.X. Wilson, A.C. Weymouth-Wilson, A. Kato and G.W.J. Fleet (2013) J. Org. Chem., 78, 7380-7397. [Full text] [Supplementary data]
     
  932. Travelling wave ion mobility and negative ion fragmentation for the structural determination of N-linked glycans.
    D.J. Harvey, C.A. Scarff, M. Edgeworth, M. Crispin, C.N. Scanlan, F. Sobott, S. Allman, K. Barauh, L.K. Pritchard and J.H. Scrivens (2013) Electrophoresis, 34, 2368-2378. [Full text]
     
  933. Solution NMR analyses of the C-type carbohydrate recognition domain of DC-SIGNR reveal different binding modes for HIV-derived oligosaccharides and smaller glycan fragments.
    F. Probert, S.B. Whittaker, M. Crispin, D.A. Mitchell and A.M. Dixon (2013) J. Biol. Chem., 288, 22745-22757. [Full text] [Supplementary data]
     
  934. Increase in sialylation and branching in the mouse serum N-glycome correlates with inflammation and ovarian tumour progression.
    R. Saldova, H. Piccard, M. Pérez-Garay, D.J. Harvey, W.B. Struwe, M.C. Galligan, N. Berghmans,S.F. Madden, R. Peracaula, G. Opdenakker and P.M. Rudd (2013) PLoS One, 8, e71159. [Full text] [Supplementary data]
     
  935. Differential effect of p7 inhibitors on hepatitis C virus cell-to-cell transmission.
    L.W. Meredith, N. Zitzmann and J.A. McKeating (2013) Antiviral Res., 100, 636-639. [Full text]
     
  936. Crystal structure of sialylated IgG Fc: Implications for the mechanism of IVIg therapy.
    M. Crispin, X. Yu and T.A. Bowden (2013) Proc. Natl. Acad. Sci. USA., 110, e3544-e3546. [Full text]
     
  937. An approach to 8 stereoisomers of homonojirimycin from d-glucose via kinetic & thermodynamic azido-gamma-lactones.
    A.F.G. Glawar, S.F. Jenkinson, S.J. Newberry, A.L. Thompson, S. Nakagawa, A. Yoshihara, K. Akimitsu, K. Izumori, T.D. Butters, A. Kato and G.W.J. Fleet (2013) Org. Biomol. Chem., 11, 6886-6899. [Full text] [Supplementary data]
     
  938. Commentary - Directing stem cell differentiation with antibodies.
    M. Dalziel, M. Crispin and R.A. Dwek (2013) Proc. Natl. Acad. Sci. USA., 110, 17608-17609. [Full text]
     
  939. Gas chromatography/mass spectrometry.
    D.J. Harvey (2013) in "Chemistry, Molecular Sciences and Engineering", on line publication, article MS 00215 (Elsevier). [Full text]
     
  940. Ionization methods overview.
    D.J. Harvey (2013) in "Chemistry, Molecular Sciences and Engineering", on line publication, article MS 00320 (Elsevier). [Full text]
     
  941. MALDI.
    D.J. Harvey (2013) in "Chemistry, Molecular Sciences and Engineering", on line publication, article MS 00323 (Elsevier). [Full text]
     
  942. Rescue of functional CFTR channels in Cystic Fibrosis: A dramatic multivalent effect using iminosugar clusters-based correctors.
    P. Compain, C. Decroocq, A. Joosten, J. de Sousa, D. Rodríguez-Lucena, T.D. Butters, J. Bertrand, F. Becq and C. Norez (2013) ChemBioChem, 14, 2050-2058. [Full text]
     
  943. Heart failure in a woman with SLE, anti-phospholipid syndrome and Fabry’s disease.
    A. Nandagudi, E.C. Jury, D.S. Alonzi, T.D. Butters, S. Hughes and D.A. Isenberg (2013) Lupus, 22, 1070-1076. [Full text]

    2014 - Top-Bottom

  944. Antibody glycosylation.
    X. Yu, K. Baruah, C.N. Scanlan and M. Crispin (2014) in "Antibody Fc: linking adaptive and innate immunity", pp. 179-194, ed. M.E. Ackerman and F. Nimmerjahn (Academic Press). [Full text]
     
  945. HIV glycomics and glycoproteomics.
    C. Bonomelli, M. Crispin, C.N. Scanlan and K.J. Doores (2014) in "HIV glycans in infection and immunity", pp.1-25, ed. R. Pantophlet (Springer, New York). [Full text]
     
  946. Emerging principles for the therapeutic exploitation of glycosylation.
    M. Dalziel, M. Crispin, C.N. Scanlan, N. Zitzmann, R.A. Dwek (2014) Science, 343, 1235681. [Full text] [Supplementary data]
     
  947. A systematic investigation of iminosugar click clusters as pharmacological chaperones for the treatment of Gaucher disease.
    A. Joosten, C. Decroocq, J. de Sousa, J.P. Schneider, E. Etamé, A. Bodlenner, T.D. Butters and P. Compain (2014) ChemBioChem, 15, 309-319. [Full text] [Supplementary data]
     
  948. Normalizing glycosphingolipids restores function in CD4+ T cells from lupus patients.
    G. McDonald, S. Deepak, L. Miguel, C.J. Hall, D.A. Isenberg, A.I. Magee, T.D. Butters and E.C. Jury (2014) J. Clin. Invest., 124, 712-724. [Full text] [Supplementary data]
     
  949. Hypo-glycosylated human follicle-stimulating hormone (hFSH21/18) is much more active in vitro than fully-glycosylated hFSH (hFSH24).
    G.R. Bousfield, V.Y. Butnev, V.Y. Butnev, Y. Hiromasa, D.J. Harvey and J.V. May (2014) Moll. Cell. Endocrinol., 382, 989-997. [Full text] [Supplementary data]
     
  950. Nine of 16 stereoisomeric polyhydroxylated proline amides are potent b-N-acetylhexosaminidase inhibitors.
    B.J. Ayers, A.F.G. Glawar, R.F. Martínez, N. Ngo, Z. Liu, G.W.J. Fleet, T.D. Butters, R.J. Nash, C.-Y. Yu, M.R. Wormald, S. Nakagawa, I. Adachi, A. Kato and S.F. Jenkinson (2014) J. Org. Chem., 79, 3398-3409. [Full text] [Supplementary data]
     
  951. Non-specific accumulation of glycosphingolipids in GNE myopathy.
    K.A. Patzel, T. Yardeni, E. Le Poëc-Celic, P. Leoyklang, H. Dorward, D.S. Alonzi, N.V. Kukushkin, B. Xu, Y. Zhang, M. Sollogoub, Y. Blériot, W.A. Gahl, M. Huizing and T.D. Butters (2014) J. Inherit. Metab. Dis., 37, 297-308. [Full text] [Supplementary data]
     
  952. Journeys in Science: Glycobiology and other paths.
    R.A. Dwek (2014) Ann. Rev. Biochem., 83, 1-44. [Full text]
     
  953. Structural plasticity of the Semliki Forest virus glycome upon interspecies transmission.
    M. Crispin, D.J. Harvey, D. Bitto, C. Bonomelli, M. Edgeworth, J.H. Scrivens, J.T. Huiskonen and T.A. Bowden (2014) J. Proteome Res., 13, 1702-1712. [Full text]
     
  954. Synthesis of the enantiomers of XYLNAc and LYXNAc: comparison of ß-N-acetylhexosaminidase inhibition by the 8 stereoisomers of 2-N-acetylamino-1,2,4-trideoxy-1,4-iminopentitols.
    E.V. Crabtree, R.F. Martínez, S. Nakagawa, I. Adachi, T.D. Butters, A. Kato, G.W.J. Fleet and A.F.G. Glawar (2014) Org. Biomol. Chem., 12, 3932-3943. [Full text] [Supplementary data]
     
  955. Fragments of bacterial endoglycosidase S and immunoglobulin G reveal subdomains of each that contribute to deglycosylation.
    E.V. Dixon, J.K. Claridge, D.J. Harvey, K. Baruah, X. Yu, S. Vasiljevic, S. Mattick, L.K. Pritchard, B. Krishna, C.N. Scanlan, J.R. Schnell, M.K. Higgins, N. Zitzmann and M. Crispin (2014) J. Biol. Chem., 289, 13876-13889. [Full text]
     
  956. The role and importance of glycosylation of acute phase proteins with focus on alpha-1 antitrypsin in acute and chronic inflammatory conditions.
    C. McCarthy, R. Saldova, M.R. Wormald, P.M. Rudd, N.G. McElvaney and E.P. Reeves (2014) J. Proteome Res., 13, 3131-3143. [Full text]
     
  957. Groove-type recognition of Chlamydiaceae-specific lipopolysaccharide antigen by a family of antibodies possessing an unusual variable heavy chain N-linked glycan.
    O. Haji-Ghassemi, S. Müller-Loennies, R. Saldova, M. Muniyappa, L. Brade, P.M. Rudd, D.J. Harvey, P. Kosma, H. Brade and S.V. Evans (2014) J. Biol. Chem., 289, 16644-16661. [Full text]
     
  958. Fragmentation of negative ions from N-linked carbohydrates: Part 6. Glycans containing one N-acetylglucosamine in the core.
    D.J. Harvey, M. Edgeworth, B.A. Krishna, C. Bonomelli, S.A. Allman, M. Crispin and J.H. Scrivens (2014) Rapid Commun. Mass Spectrom., 30, 2008-2018. [Full text]
     
  959. Uukuniemi phlebovirus assembly and secretion leaves a functional imprint on the virion glycome.
    M. Crispin, D.J. Harvey, D. Bitto, S. Halldorsson, C. Bonomelli, M. Edgeworth, J.H. Scrivens, J.T. Huiskonen and T.A. Bowden (2014) J. Virol., 88, 10244-10251. [Full text]
     
  960. Nitazoxanide, an antiviral thiazolide, depletes ATP-sensitive intracellular Ca2+ stores.
    O. Ashiru, J.D. Howe and T.D. Butters (2014) Virology, 462-463, 135-148. [Full text] [Supplementary data]
     
  961. Glycosylation and Fc receptors.
    J.M. Hayes, E.F.J. Cosgrave, W.B. Struwe, M.R. Wormald, G.P. Davey, R. Jefferis and P.M. Rudd (2014) in “Fc Receptors”, Current Topics in Microbiology and Immunology, vol. 382, pp.165-199, ed. M. Daeron and F. Nimmerjahn (Springer). [Full text]
     
  962. Estimating collision cross sections of negatively charged N-glycans using travelling wave ion mobility-mass spectrometry.
    J. Hofmann, W.B. Struwe, C.A. Scarff, J.H. Scrivens, D.J. Harvey and K. Pagel (2014) Anal. Chem., 86, 10789-10795. [Full text] [Supplementary data]
     
  963. N- and C-alkylation of seven-membered iminosugars generates potent glucocerebrosidase inhibitors and F508del-CFTR correctors.
    J. Desire, M. Mondon, N. Fontelle, S. Nakagawa, Y. Hirokami, I. Adachi, R. Iwaki, G.W.J. Fleet, D.S. Alonzi, G. Twigg, T.D. Butters, J. Bertrand, V. Cendret, F. Becq, C. Norez, J. Marrot, A. Kato and Y. Bleriot (2014) Org. Biomol. Chem., 12, 8977-8996. [Full text] [Supplementary data]
     
  964. L-Fucose from vitamin C with only acetonide protection.
    Z. Liu, A. Yoshihara, M.R. Wormald, S.F. Jenkinson, V. Gibson, K. Izumori and G.W.J. Fleet (2014) Organic Letters, 16, 5663-5665. [Full text] [Supplementary data]
     
  965. Synthetic 1-deoxynojirimycin N-substituted peptides offer prolonged disruption to N-linked glycan processing.
    A.L. Aguilar, J. Escribano, P. Wentworth Jr and T.D. Butters (2014) ChemMedChem, 9, 2809-2813. [Full text] [Supplementary data]
     
  966. Identification of antibody glycosylation structures that predict monoclonal antibody Fc-effector function.
    A.W. Chung, M. Crispin, L.K. Pritchard, H. Robinson, M.K. Gorny, X. Yu, C. Bailey-Kellogg, M.E. Ackerman, C.N. Scanlan, S. Zolla-Pazner and G. Alter (2014) AIDS, 28, 2523-2530. [Full text]
     
  967. Macro- and micro-heterogeneity in pituitary and urinary follicle-stimulating hormone glycosylation.
    G.R. Bousfield, V.Y. Butnev, M.A. Rueda-Santos, A. Brown, A.S. Hall and D.J. Harvey (2014) J. Glycomics Lipidomics, 4:125, doi: 10.4172/2153-0637.1000125. [Full text]
     
  968. "Three sources and three component parts" of free oligosaccharides.
    I.U. Pismenetskaya and T.D. Butters (2014) Ukr. Biochem. J., 86, 5-17. [Full text]

    2015 - Top-Bottom

  969. Strain-specific antiviral activity of iminosugars against human influenza A viruses.
    S. Hussain, J.L. Miller, D.J. Harvey, Y. Gu, P.B. Rosenthal, N. Zitzmann and J.W. McCauley (2015) J. Antimicrob. Chemother., 70, 136-152. [Full text] [Supplementary data]
     
  970. Soluble human TLR2 ectodomain binds diacylglycerol from microbial lipopeptides and glycolipids.
    M.J. Jimenez-Dalmaroni, C.M. Radcliffe, D.J. Harvey, M.R. Wormald, P. Verdino, G.D. Ainge, D.S. Larsen, G.F. Painter, R. Ulevitch, B. Beutler, P.M. Rudd, R.A. Dwek and I.A. Wilson (2015) Innate Immunity, 21, 175-193. [Full text]
     
  971. Isolation and SAR studies of bicyclic iminosugars from Castanospermum australe as glycosidase inhibitors.
    A. Kato, Y. Hirokami, K. Kinami, Y. Tsuji, S. Miyawaki, I. Adachi, J. Hollinshead, R.J. Nash, J.L. Kiappes, N. Zitzmann, J.K. Cha, R.J. Molyneux, G.W.J. Fleet and N. Asano (2015) Phytochemistry, 111, 124-131. [Full text]
     
  972. A method for high-throughput, sensitive analysis of IgG Fc and Fab glycosylation by capillary electrophoresis.
    A.E. Mahan, J. Tedesco, K. Dionne, K. Baruah, H.D. Cheng, P.L. De Jager, D.H. Barouch, T. Suscovich, M. Ackerman, M. Crispin and G. Alter (2015) J. Immunol. Meth., 417, 34-44. [Full text]
     
  973. Targeting host-derived glycans on enveloped viruses for antibody-based vaccine design.
    M. Crispin and K.J. Doores (2015) Curr. Op. Virol., 11, 63–69. [Full text]
     
  974. Production, purification, and characterization of recombinant hFSH glycoforms for functional studies.
    V.Y. Butnev, V.Y. Butnev, J.V. May, B. Shuai, P. Tran, W.K. White, A. Brown, A.S. Hall, D.J. Harvey and G.R. Bousfield (2015) Mol. Cell. Endocrinol., 405, 42-51. [Full text] [Supplementary data]
     
  975. Insights - Breaking the allergic response by disrupting antibody glycosylation.
    M. Crispin (2015) J. Exp. Med., 212, 433. [Full text]
     
  976. 3-Fluoro-azetidine carboxylic acids and trans,trans-3,4-difluoroproline as peptide scaffolds: Inhibition of pancreatic cancer cell growth by a fluoroazetidine iminosugar.
    Z. Liu, S.F. Jenkinson, T. Vermass, I. Adachi, M.R. Wormald, Y. Hata, Y. Kurashima, A. Kaji, C.-Y. Yu, A. Kato and G.W.J. Fleet (2015) J. Org. Chem., 80, 4244-4258. [Full text] [Supplementary data]
     
  977. Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: An update covering the period 2009-2010.
    D.J. Harvey (2015) Mass Spectrom. Rev., 34, 268-422. [Full text]
     
  978. Comparison of follicle-stimulating hormone glycosylation microheterogenity by quantitative negative mode nano-electrospray mass spectrometry of peptide-N-glycanase-released oligosaccharides.
    G.R. Bousfield, V.Y. Butnev, W.K. White, A.S. Hall and D.J. Harvey (2015) J. Glycomics Lipidomics, 5:1, doi: 10.4172/2153-0637.1000129. [Full text]
     
  979. A novel iminosugar UV-12 with activity against the diverse viruses Influenza and Dengue (novel iminosugar antiviral for Influenza and Dengue).
    K.L. Warfield, E. Plummer, D.S. Alonzi, G.W. Wolfe, A. Sampath, T. Nguyen, T.D. Butters, S.G. Enterlein, E.J. Stavale, S. Shresta and U. Ramstedt (2015) Viruses, 7, 2404-2407. [Full text]
     
  980. Eliminating antibody polyreactivity through addition of N-linked glycosylation.
    G.Y. Chuang, B. Zhang, K. McKee, S. O'Dell, Y.D. Kwon, T. Zhou, J. Blinn, K. Lloyd, R. Parks, T. Von Holle, S.Y. Ko, W.P. Kong, A. Pegu, K. Wang, K. Baruah, M. Crispin, J.R. Mascola, M.A. Moody, B.F. Haynes, I.S. Georgiev and P.D. Kwong (2015) Protein Science, 24, 1019-1030. [Full text] [Supplementary data]
     
  981. Glycosphingolipid synthesis inhibition limits osteoclast activation and myeloma bone disease.
    A. Ersek, K. Xu, A. Antonopoulos, T.D. Butters, A.E. Santo, Y. Vattakuzhi, L.M. Williams, K. Goudevenou, L. Danks, A. Freidin, E. Spanoudakis, S. Parry, M. Papaioannou, E. Hatjiharissi, A. Chaidos, D.S. Alonzi, G. Twigg, M. Hu, R.A. Dwek, S.M. Haslam, I. Roberts, A. Dell, A. Rahemtulla, N.J. Horwood and A. Karadimitris (2015) J. Clin. Invest., 125, 2279-2292. [Full text] [Supplementary data]
     
  982. Glycan microheterogeneity at the PGT135 antibody recognition site on HIV-1 gp120 reveals a molecular mechanism for neutralization resistance.
    L.K. Pritchard, D.I.R. Spencer, L. Royle, S. Vasiljevic, S.A. Krumm, K.J. Doores and M. Crispin (2015) J. Virol., 89, 6952-6959. [Full text]
     
  983. A monoclonal antibody with anti-D–like activity in murine immune thrombocytopenia requires Fc domain function for immune thrombocytopenia ameliorative effects.
    X. Yu, M. Menard, G.E. Seabright, M. Crispin and A.H. Lazarus (2015) Transfusion, 55, 1501-1511. [Full text] [Supplementary data]
     
  984. Structural constraints determine the glycosylation of HIV-1 envelope trimers.
    L.K. Pritchard, S. Vasiljevic, G. Ozorowski, G.E. Seabright, A. Cupo, R. Ringe, H.J. Kim, R.W. Sanders, K.J. Doores, D.R. Burton, I.A. Wilson, A.B. Ward, J.P. Moore and M. Crispin (2015) Cell Reports, 11, 1604-1613. [Full text] [Supplementary data]
     
  985. Glycan remodeling with processing inhibitors and lectin-resistant eukaryotic cells.
    V.T. Chang, R.A. Spooner, M. Crispin and S.J. Davis (2015) in "Glyco-Engineering: Methods and Protocols", Methods in Molecular Biology, 1321, pp. 307-322, ed. A. Castilho (Springer, New York). [Full text]
     
  986. Glycan clustering stabilizes the mannose patch of HIV-1 and preserves vulnerability to broadly neutralizing antibodies.
    L.K. Pritchard, D.I. Spencer, L. Royle, C. Bonomelli, G.E. Seabright, A.-J. Behrens, D.W. Kulp, S. Menis, S.A. Krumm, D.C. Dunlop, D.J. Crispin, T.A. Bowden, C.N. Scanlan, A.B. Ward, W.R. Schief, K.J. Doores and M. Crispin (2015) Nat. Commun., 6:7479. [Full text]
     
  987. Determination of N-linked glycosylation in viral glycoproteins by negative ion mass spectrometry and ion mobility.
    D. Bitto, D.J. Harvey, S. Halldorsson, K.J. Doores, L.K. Pritchard, J.T. Huiskonen, T.A. Bowden and M. Crispin (2015) in "Carbohydrate-Based Vaccines", Methods in Molecular Biology, 1331, pp. 93-121, ed. B. Lepenies (Springer, New York). [Full text]
     
  988. Cell- and protein-directed glycosylation of native cleaved HIV-1 envelope.
    L.K. Pritchard, D.J. Harvey, C. Bonomelli, M. Crispin and K.J. Doores (2015) J. Virol., 89, 8932-8944. [Full text] [Supplementary data]
     
  989. Ion mobility mass spectrometry for ion recovery and clean-up of MS and MS/MS spectra obtained from low abundance viral samples.
    D.J. Harvey, M. Crispin, C. Bonomelli and J.H. Scrivens (2015) J. Am. Soc. Mass Spectrom., 26, 1754-1767. [Full text]
     
  990. Collision cross sections of high-mannose N-glycans in commonly observed adduct states - identification of gas-phase conformers unique to [M - H]- ions.
    W.B. Struwe, J.L. Benesch, D.J. Harvey and K. Pagel (2015) Analyst, 140, 6799-6803. [Full text] [Supplementary data]
     
  991. The BLT1 inhibitory function of alpha-1 antitrypsin augmentation therapy disrupts leukotriene B4 neutrophil signaling.
    C.A. O’Dwyer, M.E. O’Brien, M.R. Wormald, M.M. White, N. Banville, K. Hurley, C. McCarthy, N.G. McElvaney and E.P. Reeves (2015) J. Immunol., 195, 3628-3641. [Full text] [Supplementary data]
     
  992. Redirecting adenoviruses to tumour cells using therapeutic antibodies: Generation of a versatile human bispecific adaptor.
    S. Vasiljevic, E.V. Beale, C. Bonomelli, I.S. Easthope, L.K. Pritchard, G.E. Seabright, A.T. Caputo, C.N. Scanlan, M. Dalziel and M. Crispin (2015) Mol. Immunol., 68, 234-243. [Full text]
     
  993. Engineering and characterization of a fluorescent native-like HIV-1 envelope glycoprotein trimer.
    K. Sliepen, T. van Montfort, G. Ozorowski, L.K. Pritchard, M. Crispin, A.B. Ward and R.W. Sanders (2015) Biomolecules, 5, 2919-2934. [Full text]
     
  994. Influences on the design and purification of soluble, recombinant native-like HIV-1 envelope glycoprotein trimers.
    R.P. Ringe, A. Yasmeen, G. Ozorowski, E.P. Go, L.K. Pritchard, M. Guttman, T.A. Ketas, C.A. Cottrell, I.A. Wilson, R.W. Sanders, A. Cupo, M. Crispin, K.K. Lee, H. Desaire, A.B. Ward, P.J. Klasse and J.P. Moore (2015) J. Virol., 89, 12189-12210. [Full text]
     
  995. Immunogenicity of stabilized HIV-1 envelope trimers with reduced exposure of non-neutralizing epitopes.
    S.W. de Taeye, G. Ozorowski, A. Torrents de la Peńa, M. Guttman, J.P. Julien, T.L. van den Kerkhof, J.A. Burger, L.K. Pritchard, P. Pugach, A. Yasmeen, J. Crampton, J. Hu, I. Bontjer, J.L. Torres, H. Arendt, J. DeStefano, W.C. Koff, H. Schuitemaker, D. Eggink, B. Berkhout, H. Dean, C. LaBranche, S. Crotty, M. Crispin, D.C. Montefiori, P.J. Klasse, K.K. Lee, J.P. Moore, I.A. Wilson, A.B. Ward and R.W. Sanders (2015) Cell, 163, 1702-1715. [Full text] [Supplementary data]

    2016 - Top-Bottom

  996. Fragmentation and ion mobility properties of negative ions from N-linked carbohydrates: Part 7: Reduced glycans.
    D.J. Harvey and J.L. Abrahams (2016) Rapid Commun. Mass Spectrom., 30, 627-634. [Full text]
     
  997. Structural characterization and biological implications of sulfated N-glycans in a serine protease from the neotropical moth Hylesia metabus (Cramer [1775]) (Lepidoptera: Saturniidae).
    G. Cabrera, V. Salazar, R. Montesino, Y. Tambara, W.B. Struwe, E.L. Lugo, D.J. Harvey, L. Antoine, M. Rincon, B. Domon, M.D. Mendez Martinez, M. Portela, A. Gonzalez-Hernandez, A. Triguero, R. Duran, U. Lundberg, E. Vonasek and L.J. Gonzalez (2016) Glycobiology, 26, 230-250. [Full text] [Supplementary data]
     
  998. Mechanisms of escape from the PGT128 family of anti-HIV broadly neutralizing antibodies.
    S.A. Krumm, H. Mohammed, K.M. Le, M. Crispin, T. Wrin, P. Poignard, D.R. Burton and K.J. Doores (2016) Retrovirology, 13:8, doi: 10.1186/s12977-016-0241-5. [Full text] [Supplementary data]
     
  999. At least two Fc Neu5Gc residues of monoclonal antibodies are required for binding to anti-Neu5Gc antibody.
    C. Yu, K. Gao, L. Zhu, W. Wang, L. Wang, F. Zhang, C. Liu, M. Li, M.R. Wormald, P.M. Rudd and J. Wang (2016) Scientific Reports, 7:20029, doi:10.1038/srep20029. [Full text] [Supplementary data]
     
  1000. Travelling-wave ion mobility and negative ion fragmentation of high mannose N-glycans.
    D.J. Harvey, C.A. Scarff, M. Edgeworth, W.B. Struwe, K. Pagel, K. Thalassinos, M. Crispin and J.H. Scrivens (2016) J. Mass Spectrom., 51, 219-235. [Full text]
     
  1001. Iminosugars inhibit dengue virus production via inhibition of ER alpha-glucosidases – not glycolipid processing enzymes.
    A.C. Sayce, D.S. Alonzi, S.S. Killingbeck, B.E. Tyrrell, M.L. Hill, A.T. Caputo, R. Iwaki, K. Kinami, D. Ide, J.L. Kiappes, P.R. Beatty, A. Kato, E. Harris, R.A. Dwek, J.L. Miller and N. Zitzmann (2016) PLoS Negl. Trop. Dis., 10, e0004524. [Full text] [Supplementary data]
     
  1002. Inhibition of endoplasmic reticulum glucosidases is required for in vitro and in vivo dengue antiviral activity by the iminosugar UV-4.
    K.L. Warfield, E.M. Plummer, A.C. Sayce, D.S. Alonzi, W. Tang, B.E. Tyrrell, M.L. Hill, A.T. Caputo, S.S. Killingbeck, P.R. Beatty, E. Harris, R. Iwaki, K. Kinami, D. Ide, J.L. Kiappes, A. Kato, M.D. Buck, K. King, W. Eddy, M. Khaliq, A. Sampath, A.M. Treston, R.A. Dwek, S.G. Enterlein, J.L. Miller, N. Zitzmann, U. Ramstedt and S. Shresta (2016) Antiviral Res., 129, 93-98. [Full text] [Supplementary data]
     
  1003. Composition and antigenic effects of individual glycan sites of a trimeric HIV-1 envelope glycoprotein.
    A.-J. Behrens, S. Vasiljevic, L.K. Pritchard, D.J. Harvey, R.S. Andev, S.A. Krumm, W.B. Struwe, A. Cupo, A. Kumar, N. Zitzmann, G.E. Seabright, H.B. Kramer, D.I.R. Spencer, L. Royle, J.H. Lee, P.J. Klasse, D.R. Burton, I.A. Wilson, A.B. Ward, R.W. Sanders, J.P. Moore, K.J. Doores and M. Crispin (2016) Cell Reports, 14, 2695-2706. [Full text] [Supplementary data]
     
  1004. Native functionality and therapeutic targeting of arenaviral glycoproteins.
    M. Crispin, A. Zeltina, N. Zitzmann and T.A. Bowden (2016) Curr. Opin. Virol., 18, 70-75. [Full text]
     
  1005. Trimeric HIV-1-Env structures define glycan shields from clades A, B, and G.
    G.B.E. Stewart-Jones, C. Soto, T. Lemmin, G.-Y. Chuang, A. Druz, R. Kong, P.V. Thomas, K. Wagh, T. Zhou, A.-J. Behrens, T. Bylund, C.W. Choi, J.R. Davison, I.S. Georgiev, M.G. Joyce, Y.D. Kwon, M. Pancera, J. Taft, Y. Yang, B. Zhang, S.S. Shivatare, V.S. Shivatare, C.-C.D. Lee, C.-Y. Wu, C.A. Bewley, D.R. Burton, W.C. Koff, M. Connors, M. Crispin, U. Baxa, B.T. Korber, C.-H. Wong, J.R. Mascola and P.D. Kwong (2016) Cell, 165, 813-826. [Full text] [Supplementary data]
     
  1006. Ion-channel function and cross-species determinants in viral assembly of nonprimate hepacivirus p7.
    S. Walter, A. Bollenbach, J. Doerrbecker, S. Pfaender, R.J.P. Brown, G. Vieyres, C. Scott, R. Foster, A. Kumar, N. Zitzmann, S. Griffin, F. Penin, T. Pietschmann and E. Steinmann (2016) J. Virol., 90, 5075-5089. [Full text]
     
  1007. Challenges of glycosylation analysis and control: an integrated approach to producing optimal and consistent therapeutic drugs.
    P. Zhang, S. Woen, T. Wang, B. Liau, S. Zhao, C. Chen, Y. Yang, Z. Song, M.R. Wormald, C. Yu and P.M. Rudd (2016) Drug Discovery Today, 21, 740-765. [Full text]
     
  1008. GlycoMob: an ion mobility-mass spectrometry collision cross section database for glycomics.
    W.B. Struwe, K. Pagel, J.L. Benesch, D.J. Harvey and M.P. Campbell (2016) Glycoconj. J., 33, 399-404. [Full text]
     
  1009. Immune recruitment or suppression by glycan engineering of endogenous and therapeutic antibodies.
    N.P.L. Le, T.A. Bowden, W.B. Struwe and M. Crispin (2016) Biochim. Biophys. Acta, 1860, 1655-1668. [Full text]
     
  1010. Structure of a phleboviral envelope glycoprotein reveals a consolidated model of membrane fusion.
    S. Halldorsson, A.-J. Behrens, K. Harlos, J.T. Huiskonen, R.M. Elliott, M. Crispin, B. Brennan and T.A. Bowden (2016) Proc. Natl. Acad. Sci. USA., 113, 7154-7159. [Full text] [Supplementary data]
     
  1011. Comprehensive N-glycan profiling of avian Immunoglobulin Y.
    S. Gilgunn, S. Millan Martín, M.R. Wormald, J. Zapatero-Rodriguez, P.J. Conroy, R.J. O'Kennedy, P.M. Rudd and R. Saldova (2016) PLoS One, 11, e0159859. [Full text] [Supplementary data]
     
  1012. MAIT cells are activated during human viral infections.
    B. van Wilgenburg, I. Scherwitzl, E.C. Hutchinson, T. Leng, A. Kurioka, C. Kulicke, C. de Lara, S. Cole, S. Vasanawathana, W. Limpitikul, P. Malasit, D. Young, L. Denney, STOP-HCV consortium (E. Barnes, J. Ball, G. Burgess, G. Cooke, J. Dillon, C. Gore, G. Foster, N. Guha, R. Halford, C. Herath, C. Holmes, A. Howe, E. Hudson, W. Irving, S. Khakoo, D. Koletzki, N. Martin, T. Mbisa, J. McKeating, J. McLauchlan, A. Miners, A. Murray, P. Shaw, P. Simmonds, C. Spencer, P. Targett-Adams, E. Thomson, P. Vickerman, N. Zitzmann), M.D. Moore, P. Fabris, M.T. Giordani, Y.H. Oo, S.M. Laidlaw, L.B. Dustin, L.P. Ho, F.M. Thompson, N. Ramamurthy, J. Mongkolsapaya, C.B. Willberg, G.R. Screaton and P. Klenerman (2016) Nat. Commun., 7:11653. [Full text] [Supplementary data]
     
  1013. Structures of mammalian ER a-glucosidase II capture the binding modes of broad-spectrum iminosugar antivirals.
    A.T. Caputo, D.S. Alonzi, L. Marti, I.-B. Reca, J.L. Kiappes, W.B. Struwe, A. Cross, S. Basu, E.D. Lowe, B. Darlot, A. Santino, P. Roversi and N. Zitzmann (2016) Proc. Natl. Acad. Sci. USA, 113, E4630-E4638. [Full text] [Supplementary data]
     
  1014. 6-deoxyhexoses from L-rhamnose in the search for inducers of the rhamnose operon: synergy of chemistry and biotechnology.
    Z. Liu, A. Yoshihara, C. Kelly, J.T. Heap, M.H.S. Marqvorsen, S.F. Jenkinson, M.R. Wormald, J.M. Otero, A. Estévez, A. Kato, G.W.J. Fleet, R.J. Estévez and K. Izumori (2016) Chem. Eur. J., 22, 12557-12565. [Full text] [Supplementary data]
     
  1015. Triacetonide of glucoheptonic acid in the scalable syntheses of D-gulose, 6-deoxy-D-gulose, L-glucose, 6-deoxy-L-glucose, and related sugars.
    Z. Liu, A. Yoshihara, S.F. Jenkinson, M.R. Wormald, R.J. Estevez, G.W.J. Fleet and K. Izumori (2016) Org. Lett., 18, 4112-4115. [Full text] [Supplementary data]
     
  1016. 3-azidoazetidines as the first scaffolds for ß-amino azetidine carboxylic acid peptidomimetics: azetidine iminosugars containing an acetamido group do not inhibit ß-N-acetylhexosaminidases.
    Z. Liu, S.F. Jenkinson, A. Kato, S. Nakagawa, M.R. Wormald, C.-Y. Yu and G.W.J. Fleet (2016) Tetrahedron: Asymmetry, 27, 872-881. [Full text]
     
  1017. Multiple reaction monitoring and multiple reaction monitoring cubed based assay for the quantitation of apolipoprotein F.
    A. Kumar, B. Gangadharan and N. Zitzmann (2016) J. Chromatogr. B., 1033, 278-286. [Full text] [Supplementary data]
     
  1018. Travelling-wave ion mobility and negative ion fragmentation of hybrid and complex N-glycans.
    D.J. Harvey, C.A. Scarff, M. Edgeworth, K. Pagel, K. Thalassinos, W.B. Struwe, M. Crispin and J.H. Scrivens (2016) J. Mass Spectrom., 51, 1064-1079. [Full text] [Supplementary data]
     
  1019. Technical note - The minimum information required for a glycomics experiment (MIRAGE) project: sample preparation guidelines for reliable reporting of glycomics datasets.
    W.B. Struwe, S. Agravat, K.F. Aoki-Kinoshita, M.P. Campbell, C.E. Costello, A. Dell, T. Feizi, S.M. Haslam, N.G. Karlsson, K.H. Khoo, D. Kolarich, Y. Liu, R. McBride, M.V. Novotny, N.H. Packer, J.C. Paulson, E. Rapp, R. Ranzinger, P.M. Rudd, D.F. Smith, M. Tiemeyer, L. Wells, W.S. York, J. Zaia and C. Kettner (2016) Glycobiology, 26, 907-910. [Full text]
     
  1020. Synthetic chemical inducers and genetic decoupling enable orthogonal control of the rhaBAD promoter.
    C.L. Kelly, Z. Liu, A. Yoshihara, S.F. Jenkinson, M.R. Wormald, J. Otero, A. Estévez, A. Kato, M.H.S. Marqvorsen, G.W.J. Fleet, R.J. Estévez, K. Izumori and J.T. Heap (2016) ACS Synth. Biol., 5, 1136-1145. [Full text] [Supplementary data]
     
  1021. Antibody production using a ciliate generates unusual antibody glycoforms displaying enhanced cell-killing activity.
    J. Calow, A.-J. Behrens, S. Mader, U. Bockau, W.B. Struwe, D.J. Harvey, K.U. Cormann, M.M. Nowaczyk, K. Loser, D. Schinor, M.W.W. Hartmann and M. Crispin (2016) mAbs, 8, 1498-1511. [Full text] [Supplementary data]
     
  1022. Analysis of protein glycosylation by mass spectrometry.
    D.J. Harvey (2016) in "The analysis of post-translational modifications using mass spectrometry", pp.89-159, ed. J.R. Griffiths and R. Unwin (Wiley, USA). [Full text]
     
  1023. An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability.
    M.J. van Gils, T.L.G M. van den Kerkhof, G. Ozorowski, C.A. Cottrell, D. Sok, M. Pauthner, J. Pallesen, N. de Val, A. Yasmeen, S.W. de Taeye, A. Schorcht, S. Gumbs, I. Johanna, K. Saye-Francisco, C.-H. Liang, E. Landais, X. Nie, L.K. Pritchard, M. Crispin, G. Kelsoe, I.A. Wilson, H. Schuitemaker, P.J. Klasse, J.P. Moore, D.R. Burton, A.B. Ward and R.W. Sanders (2016) Nature Microbiology, 2, 16199. [Full text] [Supplementary data]
     
  1024. Fc gamma receptors: glycobiology and therapeutic prospects.
    J.M. Hayes, M.R. Wormald, P.M. Rudd and G.P. Davey (2016) J. Inflamm. Res., 9, 209-219. [Full text]
     
  1025. Minimal in vivo efficacy of iminosugars in a lethal ebola virus guinea pig model.
    J.L. Miller, S.G. Spiro, S.D. Dowall, I. Taylor, A. Rule, D.S. Alonzi, A.C. Sayce, E. Wright, E.M. Bentley, R. Thom, G. Hall, R.A. Dwek, R. Hewson and N. Zitzmann (2016) PLoS One, 11, e0167018. [Full text] [Supplementary data]
     
  1026. HIV-1 glycan density drives the persistence of the mannose patch within an infected individual.
    K. Coss, S. Vasiljevic, L.K. Pritchard, S. Krumm, M. Glaze, S. Madzorera, P.L. Moore, M. Crispin and K.J. Doores (2016) J. Virol., 90, 11132-11144. [Full text] [Supplementary data]

    2017 - Top-Bottom

  1027. Molecular architecture of the cleavage-dependent mannose patch on a soluble HIV-1 envelope glycoprotein trimer.
    A.-J. Behrens, D.J. Harvey, E. Milne, A. Cupo, A. Kumar, N. Zitzmann, W.B. Struwe, J. Moore and M. Crispin (2017) J. Virol., 91, e01894-16. [Full text] [Supplementary data]
     
  1028. Global N-glycan site occupancy of HIV-1 gp120 by metabolic engineering and high-resolution intact mass spectrometry.
    W.B. Struwe, A. Stuckmann, A.-J. Behrens, K. Pagel and M. Crispin (2017) ACS Chem. Biol., 12, 357-361. [Full text] [Supplementary data]
     
  1029. Identification of Lewis and blood group carbohydrate epitopes by ion mobility-tandem-mass spectrometry fingerprinting.
    J. Hofmann, A. Stuckmann, M. Crispin, D.J. Harvey, K. Pagel and W.B. Struwe (2017) Anal. Chem., 89, 2318-2325. [Full text] [Supplementary data]
     
  1030. Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: An update covering the period 2011-2012.
    D.J. Harvey (2017) Mass Spectrom. Rev., 36, 255-422. [Full text]
     
  1031. Iminosugar antivirals: the therapeutic sweet spot.
    D.S. Alonzi, K.A. Scott, R.A. Dwek and N. Zitzmann (2017) Biochem. Soc. Trans., 45, 571-582. [Full text]
     
  1032. On the charge density refinement of odd-order multipoles invariant under crystal point group symmetry.
    P. Roversi and R. Destro (2017) Symmetry, 9, 63. [Full text]
     
  1033. Iminosugars: promising therapeutics for influenza infection.
    B. Tyrrell, A.C. Sayce, K. Warfield, J.L. Miller and N. Zitzmann (2017) Crit. Rev. Microbiol., 43, 521-545. [Full text]
     
  1034. Improving antibody-based cancer therapeutics through glycan engineering.
    X. Yu, M.J.E. Marshall, M.S. Cragg and M. Crispin (2017) BioDrugs, 31, 151-166. [Full text]
     
  1035. The tetrameric plant lectin BanLec neutralizes HIV through bidentate binding to specific viral glycans.
    J.T.S. Hopper, S. Ambrose, O.C. Grant, S.A. Krumm, T.M. Allison, M.T. Degiacomi, M.D. Tully, L.K. Pritchard, G. Ozorowski, A.B. Ward, M. Crispin, K.J. Doores, R.J. Woods, J.L.P. Benesch, C.V. Robinson and W.B. Struwe (2017) Structure, 25, 773-782. [Full text] [Supplementary data]
     
  1036. Genome-to-genome analysis highlights the effect of the human innate and adaptive immune systems on the hepatitis C virus.
    M.A. Ansari, V. Pedergnana, C.L.C. Ip, A. Magri, A. Von Delft, D. Bonsall, N. Chaturvedi, I. Bartha, D. Smith, G. Nicholson, G. McVean, A. Trebes, P. Piazza, J. Fellay, G. Cooke, G.R. Foster, STOP-HCV Consortium (E. Barnes, J. Ball, D. Brainard, G. Burgess, G. Cooke, J. Dillon, G.R. Foster, C. Gore, N. Guha, R. Halford, C. Herath, C. Holmes, A. Howe, E. Hudson, W. Irving, S. Khakoo, P. Klenerman, D. Koletzki, N. Martin, B. Massetto, T. Mbisa, J. McHutchison, J. McKeating, J. McLauchlan, A. Miners, A. Murray, P. Shaw, P. Simmonds, C.C.A. Spencer, P. Targett-Adams, E. Thomson, P. Vickerman, N. Zitzmann), E. Hudson, J. McLauchlan, P. Simmonds, R. Bowden, P. Klenerman, E. Barnes and C.C.A. Spencer (2017) Nat. Genet., 49, 666-673. [Full text] [Supplementary data]
     
  1037. Identification and characterization of a heterotrimeric archaeal DNA polymerase holoenzyme.
    J. Yan, T.R. Beattie, A.L. Rojas, K. Schermerhorn, T. Gristwood, J.C. Trinidad, S.V. Albers, P. Roversi, A.F. Gardner, N.G.A. Abrescia and S.D. Bell (2017) Nat. Commun., 8:15075. [Full text] [Supplementary data]
     
  1038. Anharmonic motions versus dynamic disorder at the Mg ion from the charge densities in pyrope (Mg3Al2Si3O12) crystals at 30 K: six of one, half a dozen of the other.
    R. Destro, R. Ruffo, P. Roversi, R. Soave, L. Loconte and L. Lo Presti (2017) Acta Cryst., B73, 722-736. [Full text] [Supplementary data]
     
  1039. Convergent immunological solutions to Argentine hemorrhagic fever virus neutralization.
    A. Zeltina, S.A. Krumm, M. Sahin, W.B. Struwe, K. Harlos, J.H. Nunberg, M. Crispin, D.D. Pinschewer, K.J. Doores and T.A. Bowden (2017) Proc. Natl. Acad. Sci. USA, 114, 7031-7036. [Full text] [Supplementary data]
     
  1040. Interdomain conformational flexibility underpins the activity of UGGT, the eukaryotic glycoprotein secretion checkpoint.
    P. Roversi, L. Marti, A.T. Caputo, D.S. Alonzi, J.C. Hill, K.C. Dent, A. Kumar, M.D. Levasseur, A. Lia, T. Waksman, S. Basu, Y. Soto Albrecht, K. Qian, J.P. McIvor, C.B. Lipp, D. Siliqi, S. Vasiljevic, S. Mohammed, P. Lukacik, M.A. Walsh, A. Santino and N. Zitzmann (2017) Proc. Natl. Acad. Sci. USA, 114, 8544-8549. [Full text] [Supplementary data]
     
  1041. Cadherin 26 is an alpha integrin-binding epithelial immunomodulatory receptor regulated during allergic inflammation.
    J.M. Caldwell, M.H. Collins, K.A. Kemme, J.D. Sherrill, T. Wen, M. Rochman, E.M. Stucke, L. Amin, H. Tai, P.E. Putnam, M.J. Jimenez-Dalmaroni, M.R. Wormald, A. Porollo, J.P. Abonia and M.E. Rothenberg (2017) Mucosal Immunology, 10, 1190-1201. [Full text] [Supplementary data]
     
  1042. Structural principles controlling HIV envelope glycosylation.
    A.-J. Behrens and M. Crispin (2017) Curr. Opin. Struct. Biol., 44, 125-133. [Full text]
     
  1043. Glycan fingerprinting via cold-ion infrared spectroscopy.
    E. Mucha, A.I. González Flórez, M. Marianski, D.A. Thomas, W. Hoffmann, W.B. Struwe, H.S. Hahm, S. Gewinner, W. Schöllkopf, P.H. Seeberger, G. von Helden and K. Pagel (2017) Angew. Chem. Int. Ed., 56, 11248-11251. [Full text] [Supplementary data]
     
  1044. Enzymatic inactivation of endogenous IgG by IdeS enhances therapeutic antibody efficacy.
    S. Järnum, A. Runström, R. Bockermann, L. Winstedt, M. Crispin and C. Kjellman (2017) Mol. Cancer Ther., 16, 1887-1897. [Full text] [Supplementary data]
     
  1045. Reducing V3 antigenicity and immunogenicity on soluble, native-like HIV-1 Env SOSIP trimers.
    R.P. Ringe, G. Ozorowski, K. Rantalainen, W.B. Struwe, K. Matthews, J.L. Torres, A. Yasmeen, C.A. Cottrell, T.J. Ketas, C.C. LaBranche, D.C. Montefiori, A. Cupo, M. Crispin, I.A. Wilson, A.B. Ward, R.W. Sanders, P.J. Klasse and J.P. Moore (2017) J. Virol., 91, e00677-17. [Full text]
     
  1046. Improving the immunogenicity of native-like HIV-1 envelope trimers by hyperstabilization.
    A. Torrents de la Peńa, J.P. Julien, S.W. de Taeye, F. Garces, M. Guttman, G. Ozorowski, L.K. Pritchard, A.-J. Behrens, E.P. Go, J.A. Burger, E.E. Schermer, K. Sliepen, T.J. Ketas, P. Pugach, A. Yasmeen, C.A. Cottrell, J.L. Torres, C.D. Vavourakis, M.J. van Gils, C. LaBranche, D.C. Montefiori, H. Desaire, M. Crispin, P.J. Klasse, K.K. Lee, J.P. Moore, A.B. Ward, I.A. Wilson and R.W. Sanders (2017) Cell Reports, 20, 1805-1817. [Full text] [Supplementary data]
     
  1047. Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo.
    M. Medina-Ramírez, F. Garces, A. Escolano, P. Skog, S.W. de Taeye, I. Del Moral-Sanchez, A.T. McGuire, A. Yasmeen, A.-J. Behrens, G. Ozorowski, T.L.G.M. van den Kerkhof, N.T. Freund, P. Dosenovic, Y. Hua, A.D. Gitlin, A. Cupo, P. van der Woude, M. Golabek, K. Sliepen, T. Blane, N. Kootstra, M.J. van Breemen, L.K. Pritchard, R.L. Stanfield, M. Crispin, A.B. Ward, L. Stamatatos, P.J. Klasse, J.P. Moore, D. Nemazee, M.C. Nussenzweig, I.A. Wilson and R.W. Sanders (2017) J. Exp. Med., 214, 2573-2590. [Full text] [Supplementary data]
     
  1048. Absolute quantitation of disease protein biomarkers in a single LC-MS acquisition using apolipoprotein F as an example.
    A. Kumar, B. Gangadharan, J. Cobbold, M. Thursz and N. Zitzmann (2017) Scientific Reports, 7:12072. [Full text] [Supplementary data]
     
  1049. Glycosylation profiling to evaluate glycoprotein immunogens against HIV-1.
    A.-J. Behrens, W.B. Struwe and M. Crispin (2017) Expert Rev. Proteomics, 14, 881-890. [Full text]
     
  1050. Technical note - The minimum information required for a glycomics experiment (MIRAGE) project: improving the standards for reporting glycan microarray-based data.
    Y. Liu, R. McBride, M. Stoll, A.S. Palma, L. Silva, S. Agravat, K.F. Aoki-Kinoshita, M.P. Campbell, C.E. Costello, A. Dell, S.M. Haslam, N.G. Karlsson, K.H. Khoo, D. Kolarich, M.V. Novotny, N.H. Packer, R. Ranzinger, E. Rapp, P.M. Rudd, W.B. Struwe, M. Tiemeyer, L. Wells, W.S. York, J. Zaia, C. Kettner, J.C. Paulson, T. Feizi and D.F. Smith (2017) Glycobiology, 27, 280-284. [Full text] [Supplementary data]
     
  1051. Manipulation of cytokine secretion in human dendritic cells using glycopolymers with picomolar affinity for DC-SIGN.
    D.A. Mitchell, Q. Zhang, L. Voorhaar, D.M. Haddleton, S. Herath, A.S. Gleinich, H.S. Randeva, M. Crispin, H. Lehnert, R. Wallis, S. Patterson and C.R. Becer (2017) Chem. Sci., 8, 6974-6980. [Full text] [Supplementary data]
     
  1052. Elicitation of neutralizing antibodies targeting the V2 apex of the HIV envelope trimer in a wild-type animal model.
    J.E. Voss, R. Andrabi, L.E. McCoy, N. de Val, R.P. Fuller, T. Messmer, C.Y. Su, D. Sok, S.N. Khan, F. Garces, L.K. Pritchard, R.T. Wyatt, A.B. Ward, M. Crispin, I.A. Wilson and D.R. Burton (2017) Cell Rep., 21, 222-235. [Full text] [Supplementary data]
     
  1053. Fluorescence and evaporative light scattering hplc profiling of intracellular asparagine (N)-linked oligosaccharides from Saccharomyces cerevisiae using the alg8 mutant.
    I. Jalaludin, A.H. Sudin, I.M. Said, K.A. Azizan, S.N. Baharum, A.M.A. Murad, F.Di.A. Bakar, N.M. Mahadi, M.R. Wormald, D.S. Alonzi and M.M. Mackeen (2017) Malaysian Journal of Analytical Sciences, 21, 1210-1218. [Full text]
     
  1054. Letter - Immunoglobulin G Fc glycans are not essential for antibody-mediated immune suppression to murine erythrocytes.
    D. Marjoram, Y. Cruz-Leal, L. Bernardo, N.P.L. Le, M. Crispin, X. Yu, M. Uchikawa and A.H. Lazarus (2017) Blood, 130, 2902-2905. [Full text]
     
  1055. The role of the unfolded protein response in dengue virus pathogenesis.
    N. Perera, J. Miller and N. Zitzmann (2017) Cell Microbiol., 19, e12734. [Full text]
     
  1056. Targeting glycans of HIV envelope glycoproteins for vaccine design.
    A.-J. Behrens, G.E. Seabright and M. Crispin (2017) in "Chemical Biology of Glycoproteins", pp.300-357, ed. Z. Tan and L.X. Wang (Royal Soc. Chemistry, UK).
     
  1057. Essential chemistry for biochemists.
    A.L. Jonsson, M.A.J. Roberts, J.L. Kiappes and K.A. Scott (2017) Essays in Biochemistry, 61, 401-427. [Full text]

    2018 - Top-Bottom

  1058. ToP-DNJ, a selective inhibitor of endoplasmic reticulum a-glucosidase II exhibiting anti-flaviviral activity.
    J.L. Kiappes, M.L. Hill, D.S. Alonzi, J.L. Miller, R. Iwaki, A.C. Sayce, A.T. Caputo, A. Kato and N. Zitzmann (2018) ACS Chem. Biol., 13, 60-65. [Full text] [Supplementary data]
     
  1059. Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016).
    A. Kryshtafovych, R. Albrecht, A. Baslé, P. Bule, A.T. Caputo, A.L. Carvalho, K.L. Chao, R. Diskin, K. Fidelis, C.M.G.A. Fontes, F. Fredslund, H.J. Gilbert, C.W. Goulding, M.D. Hartmann, C.S. Hayes, O. Herzberg, J.C. Hill, A. Joachimiak, G.W. Kohring, R.I. Koning, L. Lo Leggio, M. Mangiagalli, K. Michalska, J. Moult, S. Najmudin, M. Nardini, V. Nardone, D. Ndeh, T.H. Nguyen, G. Pintacuda, S. Postel, M.J. van Raaij, P. Roversi, A. Shimon, A.K. Singh, E.J. Sundberg, K. Tars, N. Zitzmann and T. Schwede (2018) Proteins, 86, 27-50. [Full text]
     
  1060. cGMP production and analysis of BG505 SOSIP.664, an extensively glycosylated, trimeric HIV-1 envelope glycoprotein vaccine candidate.
    A.K. Dey, A. Cupo, G. Ozorowski, V.K. Sharma, A.-J. Behrens, E.P. Go, T.J. Ketas, A. Yasmeen, P.J. Klasse, E. Sayeed, H. Desaire, M. Crispin, I.A. Wilson, R.W. Sanders, T. Hassell, A.B. Ward and J.P. Moore (2018) Biotechnol. Bioeng., 115, 885-899. [Full text] [Supplementary data]
     
  1061. Integrity of glycosylation processing of a glycan-depleted trimeric HIV-1 immunogen targeting key B-cell lineages.
    A.-J. Behrens, A. Kumar, M. Medina-Ramirez, A. Cupo, K. Marshall, V.M. Cruz Portillo, D.J. Harvey, G. Ozorowski, N. Zitzmann, I.A. Wilson, A.B. Ward, W.B. Struwe, J.P. Moore, R.W. Sanders and M. Crispin (2018) J. Proteome Res., 17, 987-999. [Full text] [Supplementary data]
     
  1062. Perturbations of native membrane protein structure in alkyl phosphocholine detergents: A critical assessment of NMR and biophysical studies.
    C. Chipot, F. Dehez, J.R. Schnell, N. Zitzmann, E. Pebay-Peyroula, L.J. Catoire, B. Miroux, E.R.S. Kunji, G. Veglia, T.A. Cross and P. Schanda (2018) Chem. Rev., 118, 3559-3607. [Full text] [Supplementary data]
     
  1063. Glycosylation of human IgA directly inhibits influenza A and other sialic-acid-binding viruses.
    M.A. Maurer, L. Meyer, M. Bianchi, H.L. Turner, N.P.L. Le, M. Steck, A. Wyrzucki, V. Orlowski, A.B. Ward, M. Crispin and L. Hangartner (2018) Cell Rep., 23, 90-99. [Full text] [Supplementary data]
     
  1064. Quantitative mass imaging of single biological macromolecules.
    G. Young, N. Hund., D. Cole, A. Fineberg, J. Andrecka, A. Tyler, A. Olerinyova, A. Ansari, E.G. Marklund, M.P. Collier, S.A. Chandler, O. Tkachenko, J. Allen, M. Crispin, N. Billington, Y. Takagi, J.R. Sellers, C. Eichmann, P. Selenko, L. Frey, R. Riek, M.R. Galpin, W.B. Struwe, J.L.P. Benesch and P. Kukura (2018) Science, 360, 423-427. [Full text] [Supplementary data]
     
  1065. Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer.
    A. Sarkar, S. Bale, A.-J. Behrens, S. Kumar, S.K. Sharma, N. de Val, J. Pallesen, A. Irimia, D.C. Diwanji, R.L. Stanfield, A.B. Ward, M. Crispin, R.T. Wyatt and I.A. Wilson (2018) Nat. Commun., 9:1956. [Full text] [Supplementary data]
     
  1066. Structural insights into the broad-spectrum antiviral target endoplasmic reticulum alpha-glucosidase II.
    A.T. Caputo, D.S. Alonzi, J.L. Kiappes, W.B. Struwe, A. Cross, S. Basu, B. Darlot, P. Roversi and N. Zitzmann (2018) Adv. Exp. Med. Biol., 1062, 265-276.
     
  1067. Mechanisms of antiviral activity of iminosugars against dengue virus.
    J.L. Miller, B.E. Tyrrell and N. Zitzmann (2018) Adv. Exp. Med. Biol., 1062, 277-301.
     
  1068. Cleavage-independent HIV-1 trimers from CHO cell lines elicit robust autologous tier 2 neutralizing antibodies.
    S. Bale, A. Martiné, R. Wilson, A.-J. Behrens, V. Le Fourn, N. de Val, S.K. Sharma, K. Tran, J.L. Torres, P.A. Girod, A.B. Ward, M. Crispin and R.T. Wyatt (2018) Front. Immunol., 9:1116. [Full text] [Supplementary data]
     
  1069. Signature of antibody domain exchange by native mass spectrometry and collision-induced unfolding.
    Y. Watanabe, S. Vasiljevic, J.D. Allen, G.E. Seabright, H.M.E. Duyvesteyn, K.J. Doores, M. Crispin and W.B. Struwe (2018) Anal. Chem., 90, 7325-7331. [Full text] [Supplementary data]
     
  1070. Fucose migration in intact protonated glycan ions: a universal phenomenon in mass spectrometry.
    E. Mucha, M. Lettow, M. Marianski, D.A. Thomas, W.B. Struwe, D.J. Harvey, G. Meijer, P.H. Seeberger, G. von Helden and K. Pagel (2018) Angew. Chem. Int. Ed., 57, 7440-7443. [Full text] [Supplementary data]
     
  1071. Isomer information from ion mobility separation of high-mannose glycan fragments.
    D.J. Harvey, G.E. Seabright, S. Vasiljevic, M. Crispin and W.B. Struwe (2018) J. Am. Soc. Mass Spectrom., 29, 972-988. [Full text] [Supplementary data]
     
  1072. Structural studies of fucosylated N-glycans by ion mobility mass spectrometry and collision-induced fragmentation of negative ions.
    D.J. Harvey and W.B. Struwe (2018) J. Am. Soc. Mass Spectrom., 29, 1179-1193. [Full text]
     
  1073. Collision cross sections and ion mobility separation of fragment ions from complex N-glycans.
    D.J. Harvey, Y. Watanabe, J.D. Allen, P.M. Rudd, K. Pagel, M. Crispin and W.B. Struwe (2018) J. Am. Soc. Mass Spectrom., 29, 1250-1261. [Full text]
     
  1074. Structure of the Lassa virus glycan shield provides a model for immunological resistance.
    Y. Watanabe, J. Raghwani, J.D. Allen, G.E. Seabright, S. Li, F. Moser, J.T. Huiskonen, T. Strecker, T.A. Bowden and M. Crispin (2018) Proc. Natl. Acad. Sci. USA, 115, 7320-7325. [Full text] [Supplementary data]
     
  1075. Structural basis of pyrrole polymerization in human porphobilinogen deaminase.
    P. Pluta, P. Roversi, G. Bernardo-Seisdedos, A.L. Rojas, J.B. Cooper, S. Gu, R.W. Pickersgill and O. Millet (2018) Biochim. Biophys. Acta., 1862, 1948-1955. [Full text] [Supplementary data]
     
  1076. In planta preliminary screening of ER glycoprotein folding quality control (ERQC) modulators.
    L. Marti, A. Lia, I.B. Reca, P. Roversi, A. Santino and N. Zitzmann (2018) Int. J. Mol. Sci., 19, e2135. [Full text]
     
  1077. Through the barricades: overcoming the barriers to effective antibody-based cancer therapeutics.
    M. Dalziel, S.A. Beers, M.S. Cragg and M. Crispin (2018) Glycobiology, 28, 697-712. [Full text]
     
  1078. Structure-guided redesign improves NFL HIV Env trimer integrity and identifies an inter-protomer disulfide permitting post-expression cleavage.
    L. Yang, S.K. Sharma, C. Cottrell, J. Guenaga, K. Tran, R. Wilson, A.J. Behrens, M. Crispin, N. de Val and R.T. Wyatt (2018) Front. Immunol., 9:1631. [Full text]
     
  1079. N-glycan microheterogeneity regulates interactions of plasma proteins.
    D. Wu, W.B. Struwe, D.J. Harvey, M.A.J. Ferguson and C.V. Robinson (2018) Proc. Natl. Acad. Sci. USA, 115, 8763-8768. [Full text] [Supplementary data]
     
  1080. Site-specific glycosylation of virion-derived HIV-1 Env is mimicked by a soluble trimeric immunogen.
    W.B. Struwe, E. Chertova, J.D. Allen, G.E. Seabright, Y. Watanabe, D.J. Harvey, M. Medina-Ramirez, J.D. Roser, R. Smith, D. Westcott, B.F. Keele, J.W. Bess Jr, R.W. Sanders, J.D. Lifson, J.P. Moore and M. Crispin (2018) Cell Rep., 24, 1958-1966. [Full text] [Supplementary data]
     
  1081. Rational design of DNA-expressed stabilized native-like HIV-1 envelope trimers.
    Y. Aldon, P.F. McKay, J.D. Allen, G. Ozorowski, R. Felfödiné Lévai, M. Tolazzi, P. Rogers, L. He, N. de Val, K. Fábián, G. Scarlatti, J. Zhu, A.B. Ward, M. Crispin and R.J. Shattock (2018) Cell Rep., 24, 3324-3338. [Full text] [Supplementary data]
     
  1082. Re-evaluating the p7 viroporin structure.
    B.P. Oestringer, J.H. Bolivar, M. Hensen, J.K. Claridge, C. Chipot, F. Dehez, N. Holzmann, N. Zitzmann and J.R. Schnell (2018) Nature, 562, E8-E18. [Full text]
     
  1083. Optimization of Zika virus envelope protein production for ELISA and correlation of antibody titers with virus neutralization in Mexican patients from an arbovirus endemic region.
    Y.C. Kim, C. Lopez-Camacho, J.E. Nettleship, N. Rahman, M.L. Hill, L. Silva-Reyes, G. Ortiz-Martinez, G. Figueroa-Aguilar, M.A. Mar, H. Vivanco-Cid, C.S. Rollier, N. Zitzmann, M.E. Viveros-Sandoval, R.J. Owens and A. Reyes-Sandoval (2018) Virol. J., 15:193. [Full text]
     
  1084. Ataluren, a new therapeutic for alpha-1 antitrypsin deficient individuals with nonsense mutations.
    E.P. Reeves, C.A. O'Dwyer, D.M. Dunlea, M.R. Wormald, P. Hawkins, M. Alfares, D.N. Kotton, S.M. Rowe, A.A. Wilson and N.G. McElvaney (2018) Am. J. Respir. Crit. Care Med., 198, 1099-1102. [Full text]
     
  1085. Cryo-EM structures of eastern equine encephalitis virus reveal mechanisms of virus disassembly and antibody neutralization.
    S.S. Hasan, C. Sun, A.S. Kim, Y. Watanabe, C.L. Chen, T. Klose, G. Buda, M. Crispin, M.S. Diamond, W.B. Klimstra and M.G. Rossmann (2018) Cell Rep., 25, 3136-3147. [Full text] [Supplementary data]

    2019 - Top-Bottom

  1086. The circadian clock components BMAL1 and REV-ERBa regulate flavivirus replication.
    X. Zhuang, A. Magri, M. Hill, A.G. Lai, A. Kumar, S.B. Rambhatla, C.L. Donald, A.F. Lopez-Clavijo, S. Rudge, K. Pinnick, W.H. Chang, P.A.C. Wing, R. Brown, X. Qin, P. Simmonds, T.F. Baumert, D. Ray, A. Loudon, P. Balfe, M. Wakelam, S. Butterworth, A. Kohl, C.L. Jopling, N. Zitzmann and J.A. McKeating (2019) Nat. Commun., 10:377. [Full text] [Supplementary data]
     
  1087. In-depth structural analysis of glycans in the gas phase.
    E. Mucha, A. Stuckmann, M. Marianski, W.B. Struwe, G. Meijer and K. Pagel (2019) Chem. Sci., 10, 1272-1284. [Full text]
     
  1088. Technical note: The minimum information required for a glycomics experiment (MIRAGE) project: LC guidelines.
    M.P. Campbell, J.L. Abrahams, E. Rapp, W.B. Struwe, C.E. Costello, M. Novotny, R. Ranzinger, W.S. York, D. Kolarich, P.M. Rudd and C. Kettner (2019) Glycobiology, 29, 2349-354. [Full text] [Supplementary data]
     
  1089. Circulating truncated alpha-1 antitrypsin glycoprotein in patient plasma retains anti-inflammatory capacity.
    E.P. Reeves, D.M. Dunlea, K. McQuillan, C.A. O'Dwyer, T.P. Carroll, R. Saldova, P.R. Akepati, M.R. Wormald, O.J. McElvaney, V. Shutchaidat, M. Henry, P. Meleady, J. Keenan, D.C. Liberti, D.N. Kotton, P.M. Rudd, A.A. Wilson and N.G. McElvaney (2019) J. Immunol., 202, 2240-2253. [Full text] [Supplementary data]
     
  1090. Protein and glycan mimicry in HIV vaccine design.
    G.E. Seabright, K.J. Doores, D.R. Burton and M. Crispin (2019) J. Mol. Biol., 432, 2223-2247. [Full text]
     
  1091. Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence.
    K. Sliepen, B.W. Han, I. Bontjer, P. Mooij, F. Garces, A.-J. Behrens, K. Rantalainen, S. Kumar, A. Sarkar, P.J.M. Brouwer,Y. Hua, M. Tolazzi, E. Schermer, J.L. Torres, G. Ozorowski, P. van der Woude, A.T. de la Peńa, M.J. van Breemen, J.M. Camacho-Sánchez, J.A. Burger, M. Medina-Ramírez, N. González, J. Alcami, C. LaBranche, G. Scarlatti, M.J. van Gils, M. Crispin, D.C. Montefiori, A.B. Ward, G. Koopman, J.P. Moore, R.J. Shattock, W.M. Bogers, I.A. Wilson and R.W. Sanders (2019) Nat. Commun., 10:2355. [Full text] [Supplementary data]
     
  1092. Hepatitis C virus sequence divergence preserves p7 viroporin structural and dynamic features.
    B. Oestringer, J.H. Bolivar, J.K. Claridge, L. Almanea, C. Chipot, F. Dehez, N. Holzmann, J.R. Schnell and N. Zitzmann (2019) Scientific Reports, 9:8383. [Full text] [Supplementary data]
     
  1093. Isolation from Stevia rebaudiana of DMDP acetic acid, a new class of iminosugar amino acid: synthesis and glycosidase inhibition profile of glycine and ß-alanine pyrrolidine amino acids.
    R.F. Martinez, S.F. Jenkinson, S. Nakagawa, A. Kato, M.R. Wormald, G.W.J. Fleet, J. Hollinshead and R.J. Nash (2019) Amino Acids, 51, 991-998. [Full text] [Supplementary data]
     
  1094. A cost-effectiveness analysis of shortened direct-acting antiviral treatment in genotype 1 noncirrhotic treatment-naive patients with chronic hepatitis C virus.
    C.G. Fawsitt, P. Vickerman, G. Cooke, N.J. Welton and STOP-HCV Consortium (E. Barnes, J. Ball, D. Brainard, G. Burgess, G. Cooke, J. Dillon, G.R. Foster, C. Gore, N. Guha, R. Halford, K. Whitby, C. Holmes, A. Howe, E. Hudson, S. Hutchinson, W. Irving, S. Khakoo, P. Klenerman, N. Martin, B. Massetto, T. Mbisa, J. McHutchison, J. McKeating, J. McLauchlan, A. Miners, A. Murray, P. Shaw, P. Simmonds, C.C.A. Spencer, E. Thomson, P. Vickerman, N. Zitzmann) (2019) Value Health, 22, 693-703. [Full text] [Supplementary data]
     
  1095. Exploitation of glycosylation in enveloped virus pathobiology.
    Y. Watanabe, T.A. Bowden, I.A. Wilson and M. Crispin (2019) Biochim. Biophys. Acta, 1863, 1480-1497. [Full text]
     
  1096. a-Glucosidase inhibition of lactone intermediates of the iminosugar deoxynojirimycin.
    Y.W. Haan, H. Al-Bajalan, E.E. Sage, D. Elangovan, N.L.M. Yajit, N.M. Sarizan, N. Zitzmann, J.L. Kiappes, S.A. Hasbullah, N.H. Ismail and M.M. Mackeen (2019) Jurnal Teknologi, 81, 121-128. [Full text]
     
  1097. Interferon lambda 4 impacts the genetic diversity of hepatitis C virus.
    M.A. Ansari, E. Aranday-Cortes, C.L. Ip, A. da Silva Filipe, S.H. Lau, C. Bamford, D. Bonsall, A. Trebes, P. Piazza, V. Sreenu, V.M. Cowto, STOP-HCV Consortium (J. Ball, E. Barnes, G. Burgess, G. Cooke, J. Dillon, G. Foster, C. Gore, N. Guha, R. Halford, C. Holmes, E. Hudson, S. Hutchinson, W. Irving, S. Khakoo, P. Klenerman, N. Martin, T. Mbisa, J. McKeating, J. McLauchlan, A. Miners, A. Murray, P. Shaw, P. Simmonds, S. Smith, C. Spencer, E. Thomson, P. Troke, P. Vickerman, N. Zitzmann), E. Hudson, R. Bowden, A.H. Patel, G.R. Foster, W.L Irving, K. Agarwal, E.C. Thomson, P. Simmonds, P. Klenerman, C. Holmes, E. Barnes, C.C. Spencer, J. McLauchlan and V. Pedergnana (2019) Elife, 8:e42463. [Full text] [Supplementary data]
     
  1098. Separation of isomeric O-glycans by ion mobility and liquid chromatography-mass spectrometry.
    C. Jin, D.J. Harvey, W.B. Struwe and N.G. Karlsson (2019) Anal. Chem., 91, 10604-10613. [Full text] [Supplementary data]
     
  1099. Separation of isomeric glycans by ion mobility spectrometry - the impact of fluorescent labelling.
    C. Manz, M. Grabarics, F. Hoberg, M. Pugini, A. Stuckmann, W.B. Struwe and K. Pagel (2019) Analyst, 144, 5292-5298. [Full text] [Supplementary data]
     
  1100. Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle.
    P.J.M. Brouwer, A. Antanasijevic, Z. Berndsen, A. Yasmeen, B. Fiala, T.P.L. Bijl, I. Bontjer, J.B. Bale, W. Sheffler, J.D. Allen, A. Schorcht, J.A. Burger, M. Camacho, D. Ellis, C.A. Cottrell, A.J. Behrens, M. Catalano, I. Del Moral-Sánchez, T.J. Ketas, C. LaBranche, M.J. van Gils, K. Sliepen, L.J. Stewart, M. Crispin, D.C. Montefiori, D. Baker, J.P. Moore, P.J. Klasse, A.B. Ward, N.P. King and R.W. Sanders (2019) Nat. Commun., 10:4272. [Full text] [Supplementary data]
     
  1101. Iminosugars counteract the downregulation of the interferon gamma receptor by dengue virus.
    J.L. Miller, M.L. Hill, J. Brun, A. Pountain, A.C. Sayce and N. Zitzmann (2019) Antiviral Res., 170, 104551. [Full text] [Supplementary data]
     
  1102. Use of modified Clostridium perfringens enterotoxin fragments for claudin targeting in liver and skin cells.
    L. Beier, J. Rossa, S. Woodhouse, S. Bergmann, H. Kramer, J. Protze, M. Eichner, A. Piontek, S. Vidal-y-Sy, J. Brandner, G. Krause, N. Zitzmann and J. Piontek (2019) Int. J. Mol. Sci., 20, 4774. [Full text] [Supplementary data]
     
  1103. D-Idose, D-iduronic acid and D-idonic acid from D-glucose via seven carbon sugars.
    Z. Liu, S.F. Jenkinson, A. Yoshihara, M.R. Wormald, K. Izumori and G.W.J. Fleet (2019) Molecules, 24, e3758. [Full text]
     
  1104. Mass spectrometry-based proteomic techniques to identify cerebrospinal fluid biomarkers for diagnosing suspected central nervous system infections. A systematic review.
    T. Bharucha, B. Gangadharan, A. Kumar, X. de Lamballerie, P. Newton, M. Winterberg, A. Dubot-Pérčs and N. Zitzmann (2019) J. Infection, 79, 407-418. [Full text] [Supplementary data]
     
  1105. Scientific Fundamentals of Biotechnology | Glycomics.
    E.F.J. Cosgrave, J.J. Kattla, M.P. Campbell, W.B. Struwe, M.R. Wormald and P.M. Rudd (2019) in "Comprehensive Biotechnology", 3rd edition, vol 1, p.413-434, ed. M. Moo-Young, pub. Elsevier.

    2020 - Top-Bottom

  1106. Hanessian-Hullar reaction in the synthesis of highly substituted trans-3,4-dihydroxypyrrolidines: rhamnulose iminosugar mimics inhibit alpha-glucosidase.
    Z. Liu, A. Yoshihara, S.F. Jenkinson, M.R. Wormald, C. Kelly, J.T. Heap, M.H.S. Marqvorsen, R.J. Estévez, G.W.J. Fleet, S. Nakagawa, K. Izumori, R.J Nash and A. Kato (2020) Tetrahedron, 76, 130758. [Full text] [Supplementary data]
     
  1107. Ion mobility-mass spectrometry of glycoconjugates.
    W.B. Struwe and D.J. Harvey (2020) Methods Mol. Biol., 2084, 203-219. [Full text]
     
  1108. Cost-effectiveness analysis of baseline testing for resistance-associated polymorphisms to optimize treatment outcome in genotype 1 noncirrhotic treatment-naďve patients with chronic hepatitis C virus.
    C.G. Fawsitt, P. Vickerman, G.S. Cooke and STOP-HCV Consortium (E. Barnes, J. Ball, D. Brainard, G. Burgess, G.S. Cooke, J. Dillon, G. Foster, C. Gore, N. Guha, R. Halford, K. Whitby, C. Holmes, A. Howe, E. Hudson, S. Hutchinson, W. Irving, S. Khakoo, P. Klenerman, N. Martin, B. Massetto, T. Mbisa, J. McHutchison, J. McKeating, J. McLauchlan, A. Miners, A. Murray, P. Shaw, P. Simmonds, C. Spencer, E. Thomson, P. Vickerman, N. Zitzmann) (2019) Value Health, 23, 180-190. [Full text] [Supplementary data]
     
  1109. Analysis of free oligosaccharides (fOS) from wild-type Saccharomyces cerevisiae (baker’s yeast) using two different extraction methods.
    I. Jalaludin, A.H. Sudin, D. Elangovan, H.M. Al-Bajalan, N.M. Sarizan, N.L.M. Yajit, K.A. Azizan, A.M.A. Murad, F.D.A. Bakar, D.S. Alonzi and M.M. Mackeen (2020) Sains Malaysiana, 49, 85-92. [Full text]
     
  1110. Targeting ER a-glucosidase I with a single-dose iminosugar treatment protects against lethal influenza and dengue virus infections.
    K. Warfield, D. Alonzi, J. Hill, A. Caputo, P. Roversi, J.L. Kiappes, N. Sheets, M. Duchars, R. Dwek, J. Biggins, D.L. Barnard, S. Shresta, A. Treston and N. Zitzmann (2020) J. Med. Chem., 63, 4205-4214. [Full text] [Supplementary data]
     
  1111. A need to raise the bar - A systematic review of temporal trends in diagnostics for Japanese encephalitis virus infection, and perspectives for future research.
    T. Bharucha, F.M. Shearer, M. Vongsouvath, M. Mayxay, X. de Lamballerie, P.N. Newton, N. Zitzmann, E. Gould and A. Dubot-Pérčs, (2020), Int. J. Infect. Dis., 95, 444-456. [Full text] [Supplementary data]
     
  1112. STROBE-metagenomics: a STROBE extension statement to guide the reporting of metagenomics studies.
    T. Bharucha, C. Oeser, F. Balloux, J.R. Brown, E.C. Carbo, A. Charlett, C.Y. Chiu, E.C.J. Claas, M.C. de Goffau, J.J.C. de Vries, M. Eloit, S. Hopkins, J.F. Huggett, D. MacCannell, S. Morfopoulou, A. Nath, D.M. O’Sullivan, L.B. Reoma, L.P. Shaw, I. Sidorov, P.J. Simner, L. Van Tan, E.C. Thomson, L. van Dorp, M.R. Wilson, J. Breuer and N. Field (2020) Lancet - Infectious Diseases, S1473-3099(20)30199-7. [Full text] [Supplementary data]
     
  1113. Site-specific glycan analysis of the SARS-CoV-2 spike.
    Y. Watanabe, J.D. Allen, D. Wrapp, J.S. McLellan and M. Crispin (2020) Science, 369, 330-333. [Full text] [Supplementary data]
     
  1114. The benefits of simulations as remote exercises during the Covid-19 pandemic: An enzyme kinetics case study.
    A.F. Worrall, P.E. Bergstrom Mann, D. Young, M.R. Wormald, S.T. Cahill and M.I. Stewart (2020) J. Chem. Ed., 97, 2733-2737. [Full text]
     
  1115. Networks of HIV-1 envelope glycans maintain antibody epitopes in the face of glycan additions and deletions.
    G.E. Seabright, C.A. Cottrell, M.J. van Gils, A. D'addabbo, D.J. Harvey, A.J. Behrens, J.D. Allen, Y. Watanabe, N. Scaringi, T.M. Polveroni, A. Maker, S. Vasiljevic, N. de Val, R.W. Sanders, A.B. Ward and M. Crispin (2020) Structure, 28, 897-909. [Full text] [Supplementary data]
     
  1116. Vulnerabilities in coronavirus glycan shields despite extensive glycosylation.
    Y. Watanabe, Z.T. Berndsen, J. Raghwani, G.E. Seabright, J.D. Allen, O.G. Pybus, J.S. McLellan, I.A. Wilson, T.A. Bowden, A.B. Ward and M. Crispin (2020) Nat. Commun., 11:2688. [Full text] [Supplementary data]
     
  1117. Allosteric inhibition of the SARS-CoV-2 main protease - insights from mass spectrometry-based assays.
    T.J. El-Baba, C.A. Lutomski, A.L. Kantsadi, T.R. Malla, T. John, V. Mikhailov, J.R. Bolla, C.J. Schofield, N. Zitzmann, I. Vakonakis and C.V. Robinson (2020), Angew. Chem. Int. Ed. Engl., 59, 23544-23548. [Full text] [Supplementary data]
     
  1118. Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target.
    L.F. Sobala, P.Z. Fernandes, Z. Hakki, A.J. Thompson, J.D. Howe, M. Hill, N. Zitzmann, S. Davis, Z. Stamataki, T.D. Butters, D.S. Alonzi, S.J. Williams and G.J. Davies (2020) Proc. Natl. Acad. Sci. USA, 117, 29595-29601. [Full text] [Supplementary data]
     
  1119. SARS-CoV-2 seroprevalence and asymptomatic viral carriage in healthcare workers: a cross-sectional study.
    A. Shields, S.E. Faustini, M. Perez-Toledo, S. Jossi, E. Aldera, J.D. Allen, S. Al-Taei, C. Backhouse, A. Bosworth, L.A. Dunbar, D. Ebanks, B. Emmanuel, M. Garvey, J. Gray, I.M. Kidd, G. McGinnell, D.E. McLoughlin, G. Morley, J. O'Neill, D. Papakonstantinou, O. Pickles, C. Poxon, M. Richter, E.M. Walker, K. Wanigasooriya, Y. Watanabe, C. Whalley, A.E. Zielinska, M. Crispin, D.C. Wraith, A.D. Beggs, A.F. Cunningham, M.T. Drayson and A.G. Richter (2020) Thorax, 75, 1089-1094. [Full text]

    2021 - Top-Bottom

  1120. In vivo modification of the goat mammary gland glycosylation pathway.
    M.J. Leiva-Carrasco, S. Jiménez-Chávez, D.J. Harvey, N.C. Parra, K.C. Tavares, F. Camacho, A. González, O. Sánchez, R. Montesino and J.R. Toledo (2021) N. Biotechnol., 61, 11-21. [Full text]
     
  1121. Subtle influence of ACE2 glycan processing on SARS-CoV-2 recognition.
    J.D. Allen, Y. Watanabe, H. Chawla, M.L. Newby and M. Crispin (2021) J. Mol. Biol., 433, 166762. [Full text] [Supplementary data]
     
  1122. Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection.
    P.J.M. Brouwer, M. Brinkkemper, P. Maisonnasse, N. Dereuddre-Bosquet, M. Grobben, M. Claireaux, M. de Gast, R. Marlin, V. Chesnais, S. Diry, J.D. Allen, Y. Watanabe, J.M. Giezen, G. Kerster, H.L. Turner, K. van der Straten, C.A. van der Linden, Y. Aldon, T. Naninck, I. Bontjer, J.A. Burger, M. Poniman, A.Z. Mykytyn, N.M.A. Okba, E.E. Schermer, M.J. van Breemen, R. Ravichandran, T.G. Caniels, J. van Schooten, N. Kahlaoui, V. Contreras, J. Lemaître, C. Chapon, R.H.T. Fang, J. Villaudy, K. Sliepen, Y.U. van der Velden, B.L. Haagmans, G.J. de Bree, E. Ginoux, A.B. Ward, M. Crispin, N.P. King, S. van der Werf, M.J. van Gils, R. Le Grand and R.W. Sanders (2021) Cell, 184, 1188-1200. [Full text] [Supplementary data]
     
  1123. Assessing antigen structural integrity through glycosylation analysis of the SARS-CoV-2 viral spike.
    J. Brun, S. Vasiljevic, B. Gangadharan, M. Hensen, A.V. Chandran, M.L. Hill, J.L. Kiappes, R.A. Dwek, D.S. Alonzi, W.B. Struwe and N. Zitzmann (2021) ACS Central Science, 7, 586-593. [Full text] [Supplementary data] [Movie 1] [Movie 2]
     
  1124. Native-like SARS-CoV-2 Spike Glycoprotein Expressed by ChAdOx1 nCoV-19/AZD1222 Vaccine.
    Y. Watanabe, L. Mendonça, E.R. Allen, A.Howe, M. Lee, J.D. Allen, H. Chawla, D. Pulido, F. Donnellan, H. Davies, M. Ulaszewska, S. Belij-Rammerstorfer, S. Morris, A.S. Krebs, W. Dejnirattisai, J. Mongkolsapaya, P. Supasa, G.R. Screaton, C.M. Green, T. Lambe, P. Zhang, S.C. Gilbert and M. Crispin (2021) ACS Central Science, 7, 594-602. [Full text] [Supplementary data] [Movie 1]
     
  1125. A cross-neutralizing antibody between HIV-1 and influenza virus.
    C.-C.D. Lee, Y. Watanabe, N.C. Wu, J. Han, S. Kumar, T. Pholcharee, G.E. Seabright, J.D. Allen, C.-W. Lin, J.-R. Yang, M.-T. Liu, C.-Y. Wu, A.B. Ward, M. Crispin and I.A. Wilson (2021) PLoS Pathog., 17, e1009407. [Full text]
     
  1126. Enhancing glycan occupancy of soluble HIV-1 envelope trimers to mimic the native viral spike.
    R. Derking, J.D. Allen, C.A. Cottrell, K. Sliepen, G.E. Seabright, W.H. Lee, Y. Aldon, K. Rantalainen, A. Antanasijevic, J. Copps, A. Yasmeen, A. Cupo, V.M. Cruz Portillo, M. Poniman, N. Bol, P. van der Woude, S.W. de Taeye, T.L.G.M. van den Kerkhof, P.J. Klasse, G. Ozorowski, M.J. van Gils, J.P. Moore, A.B. Ward, M. Crispin and R.W. Sanders (2021) Cell Rep., 35, 108933. [Full text] [Supplementary data]
     
  1127. Clamping, bending, and twisting inter-domain motions in the misfold-recognising portion of UDP-glucose:glycoprotein glucosyl-transferase.
    C.P. Modenutti, J.I. Blanco Capurro, R. Ibba, S. Vasiljevic, M. Hensen, D.S. Alonzi, A.V. Chandran, J.C. Hill, J. Rushton, A. Kumar, S. Rubichi, A. Lia, G. Tax, L. Marti, A. Santino, M.A. Martí, N. Zitzmann and P. Roversi (2020) Structure, 29, 357-370. [Full text] [Supplementary data] [Movie 1] [Movie 2] [Movie 3] [Movie 4]
     
  1128. Letter to the editor - SARS-CoV-2-specific IgG1/IgG3 but not IgM in children with Pediatric Inflammatory Multi-System Syndrome.
    M. Perez-Toledo, S.E. Faustini, S.E. Jossi, A.M. Shields, E. Marcial-Juarez, H.K. Kanthimathinathan, J.D. Allen, Y. Watanabe, M. Goodall, B.E. Willcox, C.R. Willcox, M. Salim, D.C. Wraith, T.V. Veenith, E. Syrimi, M.T. Drayson, D. Jyothish, E. Al-Abadi, A. Chikermane, S.B. Welch, K. Masilamani, S. Hackett, M. Crispin, B.R. Scholefield, A.F. Cunningham and A.G. Richter (2021) Pediatr. Allergy Immunol., 32, 1125-1129. [Full text]
     
  1129. Development of a high-sensitivity ELISA detecting IgG, IgA and IgM antibodies to the SARS-CoV-2 spike glycoprotein in serum and saliva.
    S.E. Faustini, S.E. Jossi, M. Perez-Toledo, A.M. Shields, J.D. Allen, Y. Watanabe, M.L. Newby, A. Cook, C.R. Willcox, M. Salim, M. Goodall, J.L Heaney, E. Marcial-Juarez, G.L. Morley, B. Torlinska, D.C. Wraith, T.V. Veenith, S. Harding, S. Jolles, M.J. Ponsford, T. Plant, A. Huissoon, M.K. O'Shea, B.E. Willcox, M.T. Drayson, M. Crispin, A.F. Cunningham and A.G. Richter (2021) Immunology, 164, 135-147. [Full text] [Supplementary data]
     
  1130. Hepatitis C virus E2 envelope glycoprotein produced in Nicotiana benthamiana triggers humoral response with virus-neutralizing activity in vaccinated mice.
    M.O. Dobrica, A. van Eerde, C. Tucureanu, A. Onu, L. Paruch, I. Caras, E. Vlase, H. Steen, S. Haugslien, D. Alonzi, N. Zitzmann, R. Bock, J. Dubuisson, C.I. Popescu, C. Stavaru, J.L. Clarke and N. Branza-Nichita (2021) Plant Biotechnol. J., 19, 2027-2039. [Full text] [Supplementary data]
     
  1131. Iminosugar C-glycosides work as pharmacological chaperones of NAGLU, a glycosidase involved in MPS IIIB rare disease.
    S. Zhu, Y. Jagadeesh, A.T. Tran, S. Imaeda, A. Boraston, D.S. Alonzi, A. Poveda, Y. Zhang, J. Désiré, J. Charollais-Thoenig, S. Demotz, A. Kato, T.D. Butters, J. Jiménez-Barbero, M. Sollogoub and Y. Blériot (2021) Chem. Eur. J., 27, 11291-11297. [Full text] [Supplementary data]
     
  1132. Pathogen-induced inflammation is attenuated by the iminosugar MON-DNJ via modulation of the unfolded protein response.
    A.C. Sayce, F.O. Martinez, B.E. Tyrrell, N. Perera, M.L. Hill, R.A. Dwek, J.L. Miller and N. Zitzmann (2021) Immunology, 164, 587-601. [Full text] [Supplementary data]
     
  1133. Identification of N-glycans with GalNAc-containing antennae from recombinant HIV trimers by ion mobility and negative ion fragmentation.
    D.J. Harvey, A.-J. Behrens, M. Crispin and W.B. Struwe (2021) Anal. Bioanal. Chem., 413, 7229-7240. [Full text]
     
  1134. Formation and fragmentation of doubly and triply charged ions in the negative ion spectra of neutral N-glycans from viral and other glycoproteins.
    D.J. Harvey, W.B. Struwe, A.-J. Behrens, S. Vasiljevic and M. Crispin (2021) Anal. Bioanal. Chem., 413, 7277-7294. [Full text]
     
  1135. Human basigin (CD147) does not directly interact with SARS-CoV-2 spike glycoprotein.
    R.J. Ragotte, D. Pulido, F.R. Donnellan, M.L. Hill, G. Gorini, H. Davies, J. Brun, K. McHugh, L.D.W. King, K. Skinner, K. Miura, C.A. Long, N. Zitzmann and S.J. Draper (2021) mSphere, 6, e00647-21. [Full text] [Supplementary data]
     
  1136. Insertion of atypical glycans into the tumor antigen-binding site identifies DLBCLs with distinct origin and behavior.
    G. Chiodin, J.D. Allen, D.J. Bryant, P. Rock, E.A. Martino, B. Valle-Argos, P.J. Duriez, Y. Watanabe, I. Henderson, J.S. Blachly, K.J. McCann, J.C. Strefford, G. Packham, T.B.H. Geijtenbeek, C.G. Figdor, G.W. Wright, L.M. Staudt, R. Burack, T.A. Bowden, M. Crispin, F.K. Stevenson and F. Forconi (2021) Blood, 138, 1570-1582. [Full text] [Supplementary data]
     
  1137. Serological responses to SARS-CoV-2 following non-hospitalised infection: clinical and ethnodemographic features associated with the magnitude of the antibody response.
    A.M. Shields, S.E. Faustini, M. Perez-Toledo, S. Jossi, J.D. Allen, S. Al-Taei, C. Backhouse, L.A. Dunbar, D. Ebanks, B. Emmanuel, A.A. Faniyi, M. Garvey, A. Grinbergs, G. McGinnell, J. O'Neill, Y. Watanabe, M. Crispin, D.C. Wraith, A.F. Cunningham, M.T. Drayson and A.G. Richter (2021) BMJ Open Respir. Res., 8, e000872. [Full text] [Supplementary data]
     
  1138. Glycosylation and serological reactivity of an expression-enhanced SARS-CoV-2 viral spike mimetic.
    H. Chawla, S.E. Jossi, S.E. Faustini, F. Samsudin, J.D. Allen, Y. Watanabe, M.L. Newby, E. Marcial-Juárez, R.E. Lamerton, J.S. McLellan, P.J. Bond, A.G. Richter, A.F. Cunningham and M. Crispin (2021) J. Mol. Biol., 434, 167332. [Full text] [Supplementary data]
     
  1139. N-Substituted valiolamine derivatives as potent inhibitors of endoplasmic reticulum a-glucosidases I and II with antiviral activity.
    S.S. Karade, M.L. Hill, J.L. Kiappes, R. Manne, B. Aakula, N. Zitzmann, K.L. Warfield, A.M. Treston and R.A. Mariuzza (2021) J. Med. Chem., 64, 18010-18024. [Full text] [Supplementary data]

    2022 - Top-Bottom

  1140. Neutralizing antibodies to SARS-CoV-2 selected from a human antibody library constructed decades ago.
    M. Qiang, P. Ma, Y. Li, H. Liu, A. Harding, C. Min, F. Wang, L. Liu, M. Yuan, Q. Ji, P. Tao, S. Shi, Z. Li, T. Li, X. Wang, Y. Zhang, N.C. Wu, C.D. Lee, X. Zhu, J. Gilbert-Jaramillo, C. Zhang, A. Saxena, X. Huang, H. Wang, W. James, R.A. Dwek, I.A. Wilson, G. Yang and R.A. Lerner (2022) Adv. Sci., 9, e2102181. [Full text] [Supplementary data]
     
  1141. Mouse models of Japanese encephalitis virus infection: A systematic review and meta-analysis using a meta-regression approach.
    T. Bharucha, B. Cleary, A. Farmiloe, E. Sutton, H. Hayati, P. Kirkwood, L. Al Hamed, N. van Ginneken, K.S. Subramaniam, N. Zitzmann, G. Davies and L. Turtle (2022) PLoS Negl. Trop. Dis., 16, e0010116. [Full text] [Supplementary data]
     
  1142. Antiviral effects of deoxynojirimycin (DNJ)-based iminosugars in dengue virus-infected primary dendritic cells.
    N.Perera, J. Brun, D.S. Alonzi, B.E. Tyrrell, J.L. Miller and N. Zitzmann (2022) Antiviral Res., 199, 105269. [Full text]
     
  1143. Flavivirus cross-reactivity would explain the apparent findings of Japanese encephalitis virus infection in Nigeria.
    T. Bharucha, N. Zitzmann, P. Newton, A. Dubot-Pérčs and Lance Turtle (2022) J. Immunoassay Immunochem., 43, 463-465. [Full text]
     
  1144. A review of alpha-1 antitrypsin binding partners for immune regulation and potential therapeutic application.
    M.E. O'Brien, G. Murray, D. Gogoi, A. Yusuf, C. McCarthy, M.R. Wormald, M. Casey, C. Gabillard-Lefort, N.G. McElvaney and E.P. Reeves (2022) Int. J. Mol. Sci., 23, 2441. [Full text]
     
  1145. Correspondance - Host-targeting oral antiviral drugs to prevent pandemics.
    R.A. Dwek, J.I. Bell, M. Feldmann and N. Zitzmann (2022) Lancet, 399, 1381-1382. [Full text]
     
  1146. COVID-19 therapeutics: Challenges and directions for the future.
    P.C. Robinson, D.F.L. Liew, H.L. Tanner, J.R. Grainger, R.A. Dwek, R.B. Reisler, L. Steinman, M. Feldmann, L.-P. Ho, T. Hussell, P. Moss, D. Richards and N. Zitzmann (2022) Proc. Natl. Acad. Sci. USA, 119, e2119893119. [Full text]
     
  1147. Molecular basis of MHC I quality control in the peptide loading complex.
    A. Domnick, C. Winter, L. Sušac, L. Hennecke, M. Hensen, N. Zitzmann, S. Trowitzsch, C. Thomas and R. Tampé (2022) Nat. Commun., 13, 4701. [Full text] [Supplementary data]
     
     

    In press - Top-Bottom

  1148. Immunoglobulin M seroneutralization for improved confirmation of Japanese encephalitis virus infection in a flavivirus-endemic area.
    T. Bharucha, N. Ayhan, B. Pastorino, S. Rattanavong, M. Vongsouvath, M. Mayxay, A. Changthongthip, O. Sengvilaipaseuth, O. Phonemixay, J.-D. Pommier, C. Gorman, N. Zitzmann, P.N. Newton, X. de Lamballerie and A. Dubot-Pérčs (2022) Trans. R. Soc. Trop. Med. Hyg.
     
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