Department of Biochemistry University of Oxford Department of Biochemistry
University of Oxford
South Parks Road
Oxford OX1 3QU

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  1. Interaction between the Caenorhabditis elegans centriolar protein SAS-5 and microtubules facilitates organelle assembly.
    Bianchi S, Rogala KB, Dynes NJ, Hilbert M, Leidel SA, Steinmetz MO, Gönczy P, Vakonakis I.
    Mol Biol Cell 2018, 29, 722-735.
  2. Structural analysis of P. falciparum KAHRP and PfEMP1 complexes with host erythrocyte spectrin suggests a model for cytoadherent knob protrusions.
    Cutts EE, Laasch N, Reiter DM, Trenker R, Slater LM, Stansfeld PJ, Vakonakis I.
    PLoS Pathog. 2017, 13, e1006552.
  3. Coupling Form and Function: How the Oligomerisation Symmetry of the SAS-6 Protein Contributes to the Architecture of Centriole Organelles.
    Ford JE, Stansfeld PJ, Vakonakis I.
    Symmetry 2017, 9, 74.
  4. Plasmodium Helical Interspersed Subtelomeric (PHIST) Proteins, at the Center of Host Cell Remodeling.
    Warncke JD, Vakonakis I, Beck HP.
    Microbiol Mol Biol Rev. 2016, 80, 905-27.
  5. Plasmodium falciparum PHIST proteins contribute to cytoadherence and anchor PfEMP1 to the host cell cytoskeleton.
    Oberli A, Zurbrügg L, Rusch S, Brand F, Butler ME, Day JL, Cutts EE, Lavstsen T, Vakonakis I, Beck HP.
    Cell Microbiol 2016, 18, 1415-28.
  6. A spiral scaffold underlies cytoadherent knobs in Plasmodium falciparum-infected erythrocytes.
    Watermeyer JM, Hale VL, Hackett F, Clare DK, Cutts EE, Vakonakis I, Fleck RA, Blackman MJ, Saibil HR.
    Blood 2016, 21, 343-51.
  7. The centriolar protein CPAP G-box: an amyloid fibril in a single domain.
    Cutts EE, Inglis A, Stansfeld PJ, Vakonakis I, Hatzopoulos GN.
    Biochem Soc Trans 2015, 43, 838-43.
  8. The Caenorhabditis elegans protein SAS-5 forms large oligomeric assemblies critical for centriole formation.
    Rogala KB, Dynes NJ, Hatzopoulos GN, Yan J, Pong SK, Robinson CV, Deane CM, Gönczy P, Vakonakis I.
    Elife 2015, 4, doi: 10.7554/eLife.07410.
  9. A Plasmodium falciparum PHIST protein binds the virulence factor PfEMP1 and comigrates to knobs on the host cell surface.
    Oberli A, Slater LM, Cutts E, Brand F, Mundwiler-Pachlatko E, Rusch S, Masik MFG, Erat MC, Beck HP, Vakonakis I.
    FASEB J 2014, 28, 4420-33.
  10. Structural Analysis of the G-Box Domain of the Microcephaly Protein CPAP Suggests a Role in Centriole Architecture.
    Hatzopoulos GN, Erat MC, Cutts E, Rogala KB, Slater LM, Stansfeld PJ,Vakonakis I.
    Structure 2013, 21, 2069-77.
  11. Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry.
    Hilbert M, Erat MC, Hachet V, Guichard P, Blank ID, Flückiger I, Slater L, Lowe ED, Hatzopoulos GN, Steinmetz MO, Gönczy P, Vakonakis I.
    Proc Natl Acad Sci U S A. 2013, 110, 11373-8.
  12. Characterization of 14-3-3-ζ Interactions with Integrin Tails.
    Bonet R, Vakonakis I, Campbell ID.
    J Mol Biol. 2013, 425, 3060-72.
  13. Structural analysis of collagen type I interactions with human fibronectin reveals a cooperative binding mode.
    Erat MC, Sladek B, Campbell ID, Vakonakis I.
    J Biol Chem. 2013, 288, 17441-50.
  14. The GPS motif is a molecular switch for bimodal activities of adhesion class G protein-coupled receptors.
    Prömel S, Frickenhaus M, Hughes S, Mestek L, Staunton D, Woollard A, Vakonakis I, Schöneberg T, Schnabel R, Russ AP, Langenhan T.
    Cell Rep. 2012, 2, 321-31.
  15. Structural analysis of the Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) intracellular domain reveals a conserved interaction epitope.
    Mayer C, Slater L, Erat MC, Konrat R, Vakonakis I.
    J Biol Chem. 2012, 287, 7182-9.
  16. Structural basis of the 9-fold symmetry of centrioles.
    Kitagawa D, Vakonakis I, Olieric N, Hilbert M, Keller D, Olieric V, Bortfeld M, Erat MC, Flückiger I, Gönczy P, Steinmetz MO.
    Cell. 2011, 144, 364-75.
  17. The streptococcal binding site in the gelatin-binding domain of fibronectin is consistent with a non-linear arrangement of modules.
    Atkin KE, Brentnall AS, Harris G, Bingham RJ, Erat MC, Millard CJ, Schwarz-Linek U, Staunton D, Vakonakis I, Campbell ID, Potts JR.
    J Biol Chem. 2010, 285, 36977-83.
  18. Implications for collagen binding from the crystallographic structure of fibronectin 6FnI1-2FnII7FnI.
    Erat MC, Schwarz-Linek U, Pickford AR, Farndale RW, Campbell ID, Vakonakis I.
    J Biol Chem. 2010, 285, 33764-70.
  19. Multi-factorial modulation of IGD motogenic potential in MSF (migration stimulating factor).
    Ellis IR, Jones SJ, Staunton D, Vakonakis I, Norman DG, Potts JR, Milner CM, Meenan NA, Raibaud S, Ohea G, Schor AM, Schor SL.
    Exp Cell Res. 2010, 316, 2465-76.
  20. Latrophilin signaling links anterior-posterior tissue polarity and oriented cell divisions in the C. elegans embryo.
    Langenhan T, Prömel S, Mestek L, Esmaeili B, Waller-Evans H, Hennig C, Kohara Y, Avery L, Vakonakis I, Schnabel R, Russ AP.
    Dev Cell. 2009, 17, 494-504.
  21. The structure of an integrin/talin complex reveals the basis of inside-out signal transduction.
    Anthis NJ, Wegener KL, Ye F, Kim C, Goult BT, Lowe ED, Vakonakis I, Bate N, Critchley DR, Ginsberg MH, Campbell ID.
    EMBO J. 2009, 28, 3623-32.
  22. Motogenic sites in human fibronectin are masked by long range interactions.
    Vakonakis I, Staunton D, Ellis IR, Sarkies P, Flanagan A, Schor AM, Schor SL, Campbell ID.
    J Biol Chem. 2009, 284, 15668-75.
  23. Identification and structural analysis of type I collagen sites in complex with fibronectin fragments.
    Erat MC, Slatter DA, Lowe ED, Millard CJ, Farndale RW, Campbell ID, Vakonakis I.
    Proc Natl Acad Sci U S A. 2009, 106, 4195-200.
  24. Structural analysis of the interactions between paxillin LD motifs and alpha-parvin.
    Lorenz S, Vakonakis I, Lowe ED, Campbell ID, Noble ME, Hoellerer MK.
    Structure. 2008, 16, 1521-31.
  25. Solution structure and sugar-binding mechanism of mouse latrophilin-1 RBL: a 7TM receptor-attached lectin-like domain.
    Vakonakis I, Langenhan T, Prömel S, Russ A, Campbell ID.
    Structure. 2008, 16, 944-53.

Link to all Vakonakis papers on PubMed





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