Department of Biochemistry University of Oxford Department of Biochemistry
University of Oxford
South Parks Road
Oxford OX1 3QU

Tel: +44 (0)1865 613200
Fax: +44 (0)1865 613201
Image showing the global movement of lipids in a model planar membrane
Matthieu Chavent, Sansom lab
Anaphase bridges in fission yeast cells
Whitby lab
Lactose permease represented using bending cylinders in Bendix software
Caroline Dahl, Sansom lab
Epithelial cells in C. elegans showing a seam cell that failed to undergo cytokinesis
Serena Ding, Woollard lab
Collage of Drosophila third instar larva optic lobe
Lu Yang, Davis lab
First year Biochemistry students at a practical class
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Benoit Kornmann
How mitochondria integrate with the rest of cellular activity

Co-workers: Qian Feng, Arun T John Peter, Agnès Michel, Martin Peterka,
Carmelina Petrungaro, Sabine van Schie

The Kornmann Lab studies interorganelle communication. The Kornmann Laboratory studies the ultrastructural organization of the cell and the biology of organelles. Organelles are separate yet interdependent units of the eukaryotic cells. They provide an appropriate milieu for the catalysis of specific biochemical reactions. On the other hand, the compartimentalization of the cell also creates the need for ultrastructural organization of the cell and communication routes that allow the exchange of metabolites and information across the cell.

Our lab focuses mainly on mitochondria and on how mitochondria communicate with their neighboring environment in an integrated fashion. We study in particular how mitochondria integrate with the rest of cellular activity

Publications

  1. 1: Helle SCJ, Feng Q, Aebersold MJ, Hirt L, Grüter RR, Vahid A, Sirianni A,Mostowy S, Snedeker JG, Šaric A, Idema T, Zambelli T, Kornmann B. Mechanicalforce induces mitochondrial fission. Elife. 2017 Nov 9;6. pii: e30292.
     
  2. John Peter AT, Herrmann B, Antunes D, Rapaport D, Dimmer KS, Kornmann B.Vps13-Mcp1 interact at vacuole-mitochondria interfaces and bypass ER-mitochondriacontact sites. J Cell Biol. 2017 Oct 2;216(10):3219-3229.
     
  3. Michel AH, Hatakeyama R, Kimmig P, Arter M, Peter M, Matos J, De Virgilio C,Kornmann B. Functional mapping of yeast genomes by saturated transposition.Elife. 2017 May 8;6. pii: e23570.
     
  4. Lang AB, John Peter AT, Walter P, Kornmann B. ER-mitochondrial junctions canbe bypassed by dominant mutations in the endosomal protein Vps13. J Cell Biol.2015 Sep 14;210(6):883-90.
     
  5. Kanfer G, Courthéoux T, Peterka M, Meier S, Soste M, Melnik A, Reis K,Aspenström P, Peter M, Picotti P, Kornmann B. Mitotic redistribution of themitochondrial network by Miro and Cenp-F. Nat Commun. 2015 Aug 11;6:8015.
     
  6. Helle SC, Kanfer G, Kolar K, Lang A, Michel AH, Kornmann B. Organization andfunction of membrane contact sites. Biochim Biophys Acta. 2013Nov;1833(11):2526-41.
     
  7. Kornmann B, Currie E, Collins SR, Schuldiner M, Nunnari J, Weissman JS, WalterP. An ER-mitochondria tethering complex revealed by a synthetic biology screen.Science. 2009 Jul 24;325(5939):477-81.
More Publications...

Contact: benoit.kornmann@bioch.ox.ac.uk
Graduate Student and Postdoctoral Positions: Enquiries for DPhil and Postdocs are welcome.
Website: http://www.kornmann.group