Use of the Novel Plk1 Inhibitor ZK-Thiazolidinone to Elucidate Functions of Plk1 in Early and Late Stages of Mitosis

Santamaria A, Neef R, Eberspächer U, Eis K, Husemann M, Mumberg D, Prechtl S, Schulze V, Siemeister G, Wortmann L, Barr FA, Nigg EA

October 2007

Journal article

Journal:

Molecular Biology of the Cell

Volume:

Issue:

American Society for Cell Biology (ASCB)

pp.

4024 - 4036

No abstract available

Keywords:

3101 Biochemistry and Cell Biology

31 Biological Sciences

Genetics

Cancer

1.1 Normal biological development and functioning

Cancer

Generic health relevance

Anaphase

Aniline Compounds

Animals

Cell Cycle Proteins

Cell Line, Tumor

Centrosome

Chromatids

Cytokinesis

DNA Helicases

Enzyme Activation

Humans

Mice

Mitosis

Mitotic Index

Protein Kinase Inhibitors

Protein Serine-Threonine Kinases

Proto-Oncogene Proteins

Spindle Apparatus

Thiazolidines

Polo-Like Kinase 1

DOI