Micron Imaging Facility

The Micron Imaging Facility will enable you to apply the latest imaging technologies to your biological question through its state-of-the-art microscopes and expert advice and training.

The Micron Imaging Facility will enable you to apply the latest imaging technologies to your biological question through its state-of-the-art microscopes and expert advice and training.

The Micron Imaging Facility will enable you to apply the latest imaging technologies to your biological question through its state-of-the-art microscopes and expert advice and training.

The Micron Imaging Facility will enable you to apply the latest imaging technologies to your biological question through its state-of-the-art microscopes and expert advice and training.

The Micron Imaging Facility will enable you to apply the latest imaging technologies to your biological question through its state-of-the-art microscopes and expert advice and training.

In Micron we offer a full suite of facilities and services to enable biological researchers to access the latest microscope technologies. The facility team provide training and support on a wide range of microscopes ranging from super-resolution to cryo-correlative microscopy. We are happy to advise users on what system is most appropriate for their experiment and to offer help with sample preparation and experimental design. Micron also provides access to the latest image analysis, data storage and visualisation methods including super-resolution quality control, de-noising and machine learning-based image analysis. The facility in Biochemistry is partnered with many imaging facilities in other departments across Oxford through the Oxford Bioimaging Network, so users have access to the full range of the microscopes that biologists need, from wide-field deconvolution, confocal, light-sheet and 4Pi to 3DSIM, STED, dSTORM, TIRF, FCS and CLEM.

For more information, please visit https://micronoxford.com or contact us on micron@bioch.ox.ac.uk

Dr Deirdre Kavanagh

Micron Bioimaging Facility Manager

Dr Niloufer Irani

Micron Bioimaging Facility Assistant Manager

Dr Carina Monico

Micron Bioimaging Facility Assistant Manager

Prof Lothar Schermelleh

Micron Director

Advanced Proteomics Facility

The Advanced Proteomics Facility provides access to the latest proteomics technologies. It’s equipped with a wide range of mass spectrometry instrumentation, HPLC fractionation systems, sample preparation technologies and data analysis software. We provide protein, protein complex, proteome identification as routine services.

NMR Spectroscopy

Solution-state Nuclear Magnetic Resonance (NMR) spectroscopy is a method that provides detailed information about the structure, dynamics and interactions of biological macromolecules under conditions that can mimic the cellular environment.

Molecular Biophysics

We offer a range of techniques to study macromolecules and macromolecular complexes. These include analytical ultracentrifugation, differential scanning calorimetry, electrospray ionization mass spectrometry, isothermal titration calorimetry and surface plasmon resonance. All users must be registered with Dr David Staunton and receive any necessary training.

Crystallography

The Crystallography Facility enables you to apply the methods of X-ray crystallography to your biological questions. We can offer both state of the art equipment and expert advice and training in the use of crystallography for structural biology.

Scientists Discover Enzyme That Turns Air Into Electricity, Providing A New Clean Source Of Energy

A team of scientists have discovered an enzyme that converts air into energy

Research reveals the first molecular understanding of BIRC6 – an essential regulator of cell death

Latest research from the group of Paul Elliott has uncovered how BIRC6 (a giant ubiquitin ligase) protects cells...

Latest research from the group of Paul Elliott has uncovered how BIRC6 (a giant ubiquitin ligase) protects cells from death and how this can be antagonised

New Publication: "GPR97 triggers inflammatory processes in human neutrophils via a macromolecular complex upstream of PAR2 activation"

Neutrophils are a type of white blood cell that are part of our innate immune system. Their activities require...

Neutrophils are a type of white blood cell that are part of our innate immune system. Their activities require tight regulation to avoid unwanted inflammation and autoimmune diseas...

Neutrophils are a type of white blood cell that are part of our innate immune system. Their activities require tight regulation to avoid unwanted inflammation and autoimmune diseases.

Bacterial armour plating has implications for antibiotics

A new study published in the journal Science Advances sheds light on how Gram-negative bacteria like E. coli construct...

A new study published in the journal Science Advances sheds light on how Gram-negative bacteria like E. coli construct their outer membrane to resemble body armour, which has far-reaching...

A new study published in the journal Science Advances sheds light on how Gram-negative bacteria like E. coli construct their outer membrane to resemble body armour, which has far-reaching implications for the development...

A new study published in the journal Science Advances sheds light on how Gram-negative bacteria like E. coli construct their outer membrane to resemble body armour, which has far-reaching implications for the development of antibiotics

A collaborative study between Oxford, Glasgow and UKHSA discovers unexpected differences in the replication of SARS-CoV-2 variants of concern

A new study reveals differences in replication rates of SARS-CoV-2 variants of concern using single molecule RNA...

A new study reveals differences in replication rates of SARS-CoV-2 variants of concern using single molecule RNA detection

One cell, two genomes? Coordination between mitochondria and the nucleus in cancer

New paper from the Peter Sarkies research group

New therapeutic possibilities at the ‘heart’ of SARS-CoV-2 life cycle

A team led by researchers at the University of Oxford, University of Glasgow, and University of Heidelberg, uncovers...

A team led by researchers at the University of Oxford, University of Glasgow, and University of Heidelberg, uncovers the interactions that SARS-CoV-2 RNA establishes with the host cell,...

A team led by researchers at the University of Oxford, University of Glasgow, and University of Heidelberg, uncovers the interactions that SARS-CoV-2 RNA establishes with the host cell, paving the way for the development...

A team led by researchers at the University of Oxford, University of Glasgow, and University of Heidelberg, uncovers the interactions that SARS-CoV-2 RNA establishes with the host cell, paving the way for the development of new therapeutic strategies

Structure of the folate transporter paves the way for improved anticancer drugs

A new study from the Newstead group, published in Nature, reveals the structure of the folate transporter, laying...

A new study from the Newstead group, published in Nature, reveals the structure of the folate transporter, laying the foundation for developing targeted anticancer drugs

Reproducibility, transparency and access to biomedical research

The Cohn group recently developed a new method for the purification of large DNA repair protein complexes from...

The Cohn group recently developed a new method for the purification of large DNA repair protein complexes from human cells.

Compound screening for anti-viral activity

Prof. Zitzmann and her team in collaboration with other virologists from the University and support of volunteers...

Prof. Zitzmann and her team in collaboration with other virologists from the University and support of volunteers from SGC have set up an initiative for compound/biologics cellular...

Prof. Zitzmann and her team in collaboration with other virologists from the University and support of volunteers from SGC have set up an initiative for compound/biologics cellular screenings

SARS-CoV-2 Spike protein glycosylation: a vaccine quality control method

The Zitzmann lab have been working on the characterisation of the site-specific glycosylation of SARS-CoV-2 spike...

The Zitzmann lab have been working on the characterisation of the site-specific glycosylation of SARS-CoV-2 spike proteins derived from the virus and spike proteins derived from a viral...

The Zitzmann lab have been working on the characterisation of the site-specific glycosylation of SARS-CoV-2 spike proteins derived from the virus and spike proteins derived from a viral vectored SARS-CoV-2 vaccine...

The Zitzmann lab have been working on the characterisation of the site-specific glycosylation of SARS-CoV-2 spike proteins derived from the virus and spike proteins derived from a viral vectored SARS-CoV-2 vaccine candidate

Breakthrough for Optogenetics

The structure of a protein used in over 1000 labs worldwide has been resolved for the first time by an international...

The structure of a protein used in over 1000 labs worldwide has been resolved for the first time by an international team lead by the Watts lab

Micron Imaging Facility